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Search term: YML068W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ITT1
SGD link S000004533
Alternative ID YML068W
Description Protein that modulates the efficiency of translation termination, interacts with translation release factors eRF1 (Sup45p) and eRF3 (Sup35p) in vitro, contains a zinc finger domain characteristic of the TRIAD class of proteins
Synonyms YML068W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1814 AC-HYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Predicted E3 ubiquitin ligase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g32340 GI:15223171
Caenorhabditis elegans (Cel) CE11228
(WBGene00018964)		 GI:17553680 Q20874
Caenorhabditis elegans (Cel) CE11232
(WBGene00018966)		 GI:17553686 Q20871
Homo sapiens (Hsa) Hs20540967 GI:20540967
Homo sapiens (Hsa) Hs4757762
(RNF14)		 GI:4757762 Q9UBS8
Saccharomyces cerevisiae (Sce) YML068w
(S000004533)		 GI:6323572 Q04638
Schizosaccharomyces pombe (Spo) SPAC1002.14 GI:19114414 Q9US46


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
SceS000004533
GO:0005634 nucleus C
IDA
HsaRNF14
SpoSPAC1002.14
GO:0005737 cytoplasm C
IDA
HsaRNF14
GO:0005829 cytosol C
IDA
SpoSPAC1002.14
GO:0003674 molecular_function F
ND
SceS000004533
GO:0003713 transcription coactivator activity F
NAS
HsaRNF14
TAS
HsaRNF14
GO:0004842 ubiquitin-protein ligase activity F
ISS
SpoSPAC1002.14
GO:0005515 protein binding F
IPI
HsaRNF14
GO:0008270 zinc ion binding F
ISS
SpoSPAC1002.14
GO:0016563 transcription activator activity F
IDA
HsaRNF14
GO:0019787 small conjugating protein ligase
activity		 F
IDA
HsaRNF14
GO:0050681 androgen receptor binding F
IPI
HsaRNF14
GO:0000003 reproduction P
IMP
CelWBGene00018964
GO:0002119 nematode larval development P
IMP
CelWBGene00018964
GO:0006357 regulation of transcription from RNA polymerase II
promoter		 P
TAS
HsaRNF14
GO:0006449 regulation of translational termination P
IMP
SceS000004533
ISS
SpoSPAC1002.14
GO:0007165 signal transduction P
TAS
HsaRNF14
GO:0008150 biological_process P
ND
AthAt1g32340
GO:0016567 protein ubiquitination P
IEP
HsaRNF14
ISS
SpoSPAC1002.14
GO:0030521 androgen receptor signaling pathway P
NAS
HsaRNF14
GO:0032355 response to estradiol stimulus P
IDA
HsaRNF14
GO:0032583 regulation of gene-specific transcription P
IDA
HsaRNF14
GO:0040007 growth P
IMP
CelWBGene00018964
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00018964
GO:0045893 positive regulation of transcription,
DNA-dependent		 P
NAS
HsaRNF14
GO:0060765 regulation of androgen receptor signaling
pathway		 P
IDA
HsaRNF14

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2869

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Arabidopsis thaliana (Ath) ath3382 At1g32340.1
Caenorhabditis elegans (Cel) cel10598 F56D2.5
(CE11232;
WBGene00018966)
Candida glabrata (Cgl) cgl4569 CAGL0L11330g
Cryptococcus neoformans (Cne) cne5795 179.m00669
Dictyostelium discoideum (Ddi) ddi2556 DDB0190829
Dictyostelium discoideum (Ddi) ddi7074 DDB0218731
Debaryomyces hansenii (Dha) dha1069 DEHA0B08789g
Danio rerio (Dre) dre10267 ENSDARP00000005471
Danio rerio (Dre) dre10268 ENSDARP00000017558
(rnf14)		 Q6IQ68
Danio rerio (Dre) dre10269 ENSDARP00000042579
Takifugu rubripes (Fru) fru2206 SINFRUP00000162293
Takifugu rubripes (Fru) fru2207 SINFRUP00000175245
Gallus gallus (Gga) gga6087 ENSGALP00000011795
(RNF14)		 Q5ZLY7
Homo sapiens (Hsa) hsa25916 ENSP00000261809
Homo sapiens (Hsa) hsa25917 ENSP00000324956
(RNF14)		 Q9UBS8
Homo sapiens (Hsa) hsa25918 ENSP00000340531
Homo sapiens (Hsa) hsa25914 ENSP00000348462
(RNF14)		 Q9UBS8
Homo sapiens (Hsa) hsa25915 ENSP00000355174
Mus musculus (Mmu) mmu12605 ENSMUSP00000072212
(MGI:1929668)		 Q7TPR0
Neurospora crassa (Ncr) ncr3610 NCU03719.2
Oryza sativa (Osa) osa44926 5365.m00211
Oryza sativa (Osa) osa44927 5365.m00212
Oryza sativa (Osa) osa44929 5365.m00214
Oryza sativa (Osa) osa43111 5442.m00080
Oryza sativa (Osa) osa43113 5442.m00082
Saccharomyces cerevisiae (Sce) sce4672 YML068W
(S000004533)
Schizosaccharomyces pombe (Spo) spo1765 SPAC1002.14 Q9US46
Yarrowia lipolytica (Yli) yli2545 YALI0C20889g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
SceS000004533
GO:0005634 nucleus C
IDA
SpoSPAC1002.14
ISS
MmuMGI:1929668
GO:0005737 cytoplasm C
ISS
MmuMGI:1929668
GO:0005829 cytosol C
IDA
SpoSPAC1002.14
GO:0003674 molecular_function F
ND
SceS000004533
GO:0004842 ubiquitin-protein ligase activity F
ISS
SpoSPAC1002.14
GO:0008270 zinc ion binding F
ISS
SpoSPAC1002.14
GO:0019787 small conjugating protein ligase
activity		 F
ISS
MmuMGI:1929668
GO:0006449 regulation of translational termination P
IMP
SceS000004533
ISS
SpoSPAC1002.14
GO:0008150 biological_process P
ND
AthAt1g32340
GO:0008152 metabolic process P
ISS
MmuMGI:1929668
GO:0016567 protein ubiquitination P
ISS
SpoSPAC1002.14

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC1002.14
(Q9US46)		 YML068W
(S000004533)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
SceS000004533
GO:0005634 nucleus C
IDA
SpoSPAC1002.14
GO:0005829 cytosol C
IDA
SpoSPAC1002.14
GO:0003674 molecular_function F
ND
SceS000004533
GO:0004842 ubiquitin-protein ligase activity F
ISS
SpoSPAC1002.14
GO:0008270 zinc ion binding F
ISS
SpoSPAC1002.14
GO:0006449 regulation of translational termination P
IMP
SceS000004533
ISS
SpoSPAC1002.14
GO:0016567 protein ubiquitination P
ISS
SpoSPAC1002.14

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