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Search term: YML069W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name POB3
SGD link S000004534
Alternative ID YML069W
Description Subunit of the heterodimeric FACT complex (Spt16p-Pob3p), which facilitates RNA Pol II transcription elongation through nucleosomes by destabilizing and then reassembling nucleosome structure; interacts with DNA polymerase alpha (Pol1p)
Synonyms YML069W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0526 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSINGINFORMATION STORAGE AND PROCESSINGINFORMATION STORAGE AND PROCESSING Nucleosome-binding factor SPN, POB3 subunit

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g28730 GI:15228471
Caenorhabditis elegans (Cel) CE01414
(WBGene00001974)		 GI:17553930 P41848
Caenorhabditis elegans (Cel) CE08542
(WBGene00001973)		 GI:17507971 O01683
Drosophila melanogaster (Dme) 7291642 GI:12644386
Homo sapiens (Hsa) Hs4507241
(SSRP1)		 GI:4507241 Q08945
Saccharomyces cerevisiae (Sce) YML069w
(S000004534)		 GI:6323571 Q04636
Schizosaccharomyces pombe (Spo) SPBC609.05 GI:19113107 O94529
Encephalitozoon cuniculi (Ecu) ECU07g1010 GI:19074524 Q8SRJ1
Arabidopsis thaliana (Ath) At3g28730 GI:15228471
Caenorhabditis elegans (Cel) CE01414
(WBGene00001974)		 GI:17553930 P41848
Caenorhabditis elegans (Cel) CE08542
(WBGene00001973)		 GI:17507971 O01683
Drosophila melanogaster (Dme) 7291642 GI:12644386
Homo sapiens (Hsa) Hs4507241
(SSRP1)		 GI:4507241 Q08945
Saccharomyces cerevisiae (Sce) YML069w
(S000004534)		 GI:6323571 Q04636
Schizosaccharomyces pombe (Spo) SPBC609.05 GI:19113107 O94529
Encephalitozoon cuniculi (Ecu) ECU07g1010 GI:19074524 Q8SRJ1
Arabidopsis thaliana (Ath) At3g28730 GI:15228471
Caenorhabditis elegans (Cel) CE01414
(WBGene00001974)		 GI:17553930 P41848
Caenorhabditis elegans (Cel) CE08542
(WBGene00001973)		 GI:17507971 O01683
Drosophila melanogaster (Dme) 7291642 GI:12644386
Homo sapiens (Hsa) Hs4507241
(SSRP1)		 GI:4507241 Q08945
Saccharomyces cerevisiae (Sce) YML069w
(S000004534)		 GI:6323571 Q04636
Schizosaccharomyces pombe (Spo) SPBC609.05 GI:19113107 O94529
Encephalitozoon cuniculi (Ecu) ECU07g1010 GI:19074524 Q8SRJ1


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
IDA
SceS000004534
ISS
SpoSPBC609.05
GO:0005634 nucleus C
IDA
AthAt3g28730
HsaSSRP1
SpoSPBC609.05
GO:0005654 nucleoplasm C
EXP
HsaSSRP1
GO:0005658 alpha DNA polymerase:primase complex C
IDA
SceS000004534
GO:0005719 nuclear euchromatin C
IDA
AthAt3g28730
GO:0005737 cytoplasm C
IDA
HsaSSRP1
GO:0005829 cytosol C
IDA
SpoSPBC609.05
GO:0031298 replication fork protection complex C
IDA
SceS000004534
GO:0035101 FACT complex C
IDA
AthAt3g28730
SceS000004534
SpoSPBC609.05
IGI
SceS000004534
IPI
SceS000004534
GO:0043596 nuclear replication fork C
ISS
SpoSPBC609.05
GO:0003677 DNA binding F
ISS
SpoSPBC609.05
GO:0003682 chromatin binding F
IDA
SceS000004534
GO:0003700 transcription factor activity F
ISS
AthAt3g28730
GO:0003711 transcription elongation regulator
activity		 F
RCA
SceS000004534
GO:0005515 protein binding F
IPI
HsaSSRP1
SpoSPBC609.05
GO:0016944 RNA polymerase II transcription elongation factor
activity		 F
RCA
SceS000004534
GO:0031491 nucleosome binding F
IDA
SceS000004534
GO:0042393 histone binding F
IDA
SceS000004534
GO:0000003 reproduction P
IMP
CelWBGene00001974
WBGene00001973
GO:0000910 cytokinesis P
IMP
CelWBGene00001973
GO:0002119 nematode larval development P
IMP
CelWBGene00001974
WBGene00001973
GO:0006261 DNA-dependent DNA replication P
IGI
SceS000004534
IMP
SceS000004534
SpoSPBC609.05
IPI
SceS000004534
GO:0006281 DNA repair P
IMP
SpoSPBC609.05
GO:0006334 nucleosome assembly P
ISS
SpoSPBC609.05
GO:0006351 transcription, DNA-dependent P
IMP
SpoSPBC609.05
GO:0006368 RNA elongation from RNA polymerase II
promoter		 P
ISS
SpoSPBC609.05
GO:0007059 chromosome segregation P
IMP
SpoSPBC609.05
GO:0007413 axonal fasciculation P
IMP
CelWBGene00001973
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00001973
WBGene00001974
GO:0010171 body morphogenesis P
IMP
CelWBGene00001973
GO:0010228 vegetative to reproductive phase transition of
meristem		 P
IMP
AthAt3g28730
GO:0030466 chromatin silencing at silent mating-type
cassette		 P
IMP
SpoSPBC609.05
GO:0030702 chromatin silencing at centromere P
IMP
SpoSPBC609.05
GO:0034401 regulation of transcription by chromatin
organization		 P
IC
SceS000004534
GO:0034613 cellular protein localization P
ISS
SpoSPBC609.05
GO:0034724 DNA replication-independent nucleosome
organization		 P
IDA
SceS000004534
GO:0040007 growth P
IMP
CelWBGene00001973
WBGene00001974
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00001973
WBGene00001974
GO:0040011 locomotion P
IMP
CelWBGene00001974
WBGene00001973
GO:0040018 positive regulation of multicellular organism
growth		 P
IMP
CelWBGene00001973
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00001974
GO:0043486 histone exchange P
IC
SpoSPBC609.05
GO:0045899 positive regulation of RNA polymerase II
transcriptional preinitiation complex
assembly		 P
IDA
SceS000004534
GO:0051301 cell division P
IMP
CelWBGene00001973

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
113660

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) SPBC609.05 GI:19113107 O94529
Saccharomyces cerevisiae (Sce) POB3
(S000004534)		 GI:6323571 Q04636
Kluyveromyces lactis (Kla) KLLA0B04906g GI:50303621
Eremothecium gossypii (Ego) AGOS_AER138C GI:45190743
Magnaporthe grisea (Mgr) MGG_11344 GI:145614364
Neurospora crassa (Ncr) NCU00133.1 GI:32403212
Plasmodium falciparum (Pfa) PF14_0393 GI:124809408


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
IDA
SceS000004534
ISS
SpoSPBC609.05
GO:0005634 nucleus C
IDA
SpoSPBC609.05
GO:0005658 alpha DNA polymerase:primase complex C
IDA
SceS000004534
GO:0005829 cytosol C
IDA
SpoSPBC609.05
GO:0031298 replication fork protection complex C
IDA
SceS000004534
GO:0035101 FACT complex C
IDA
SceS000004534
SpoSPBC609.05
IGI
SceS000004534
IPI
SceS000004534
GO:0043596 nuclear replication fork C
ISS
SpoSPBC609.05
GO:0003677 DNA binding F
ISS
SpoSPBC609.05
GO:0003682 chromatin binding F
IDA
SceS000004534
GO:0003697 single-stranded DNA binding F
ISS
PfaPF14_0393
GO:0003711 transcription elongation regulator
activity		 F
RCA
SceS000004534
GO:0005515 protein binding F
IPI
SpoSPBC609.05
GO:0016944 RNA polymerase II transcription elongation factor
activity		 F
RCA
SceS000004534
GO:0031491 nucleosome binding F
IDA
SceS000004534
GO:0042393 histone binding F
IDA
SceS000004534
GO:0006261 DNA-dependent DNA replication P
IGI
SceS000004534
IMP
SceS000004534
SpoSPBC609.05
IPI
SceS000004534
GO:0006281 DNA repair P
IMP
SpoSPBC609.05
GO:0006334 nucleosome assembly P
ISS
SpoSPBC609.05
GO:0006351 transcription, DNA-dependent P
IMP
SpoSPBC609.05
GO:0006368 RNA elongation from RNA polymerase II
promoter		 P
ISS
SpoSPBC609.05
GO:0007059 chromosome segregation P
IMP
SpoSPBC609.05
GO:0008150 biological_process P
ND
PfaPF14_0393
GO:0030466 chromatin silencing at silent mating-type
cassette		 P
IMP
SpoSPBC609.05
GO:0030702 chromatin silencing at centromere P
IMP
SpoSPBC609.05
GO:0034401 regulation of transcription by chromatin
organization		 P
IC
SceS000004534
GO:0034613 cellular protein localization P
ISS
SpoSPBC609.05
GO:0034724 DNA replication-independent nucleosome
organization		 P
IDA
SceS000004534
GO:0043486 histone exchange P
IC
SpoSPBC609.05
GO:0045899 positive regulation of RNA polymerase II
transcriptional preinitiation complex
assembly		 P
IDA
SceS000004534

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1265

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga9537 ENSANGP00000009009
Ashbya gossypii (Ago) ago2642 AER138C
Arabidopsis thaliana (Ath) ath15235 At3g28730.1
Caenorhabditis elegans (Cel) cel3220 C32F10.5
(CE08542;
WBGene00001973)
Caenorhabditis elegans (Cel) cel15773 T20B12.8
(CE01414;
WBGene00001974)
Candida glabrata (Cgl) cgl4570 CAGL0L11352g
Dictyostelium discoideum (Ddi) ddi12898 DDB0216434
Debaryomyces hansenii (Dha) dha2850 DEHA0D12452g
Drosophila melanogaster (Dme) dme6828 CG4817-PA
(FBgn0010278)
Danio rerio (Dre) dre28853 ENSDARP00000014032
(im:7140964)		 Q6DEM6
Danio rerio (Dre) dre5131 ENSDARP00000024772
Danio rerio (Dre) dre28857 ENSDARP00000042173
Danio rerio (Dre) dre28856 ENSDARP00000043852
Danio rerio (Dre) dre28855 ENSDARP00000047343
Danio rerio (Dre) dre28854 ENSDARP00000049400
Danio rerio (Dre) dre28859 ENSDARP00000050769
Encephalitozoon cuniculi (Ecu) ecu1910 19074524
Takifugu rubripes (Fru) fru17887 SINFRUP00000166989
Gallus gallus (Gga) gga19015 ENSGALP00000012145
(SSRP1)		 Q04678
Homo sapiens (Hsa) hsa5616 ENSP00000278412
(SSRP1)		 Q08945
Kluyveromyces lactis (Kla) kla750 KLLA0B04906g
Mus musculus (Mmu) mmu14910 ENSMUSP00000028463
(MGI:107912)
Mus musculus (Mmu) mmu14911 ENSMUSP00000053130
Mus musculus (Mmu) mmu14909 ENSMUSP00000076971
(MGI:107912)		 Q08943-1
Oryza sativa (Osa) osa10114 2744.m00142
Oryza sativa (Osa) osa57297 6221.m00246
Oryza sativa (Osa) osa57611 6231.m00179
Plasmodium falciparum (Pfa) pfa1844 PF14_0393
Rattus norvegicus (Rno) rno18920 ENSRNOP00000012022
(RGD:621143)		 Q04931
Rattus norvegicus (Rno) rno18921 ENSRNOP00000049644
(RGD:621143)
Saccharomyces cerevisiae (Sce) sce4673 YML069W
(S000004534)
Schizosaccharomyces pombe (Spo) spo3897 SPBC609.05 O94529
Yarrowia lipolytica (Yli) yli3758 YALI0D25058g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
IDA
SceS000004534
ISS
SpoSPBC609.05
GO:0005575 cellular_component C
ND
MmuMGI:107912
GO:0005634 nucleus C
IDA
AthAt3g28730
SpoSPBC609.05
ISS
DmeFBgn0010278
NAS
DmeFBgn0010278
GO:0005658 alpha DNA polymerase:primase complex C
IDA
SceS000004534
GO:0005719 nuclear euchromatin C
IDA
AthAt3g28730
GO:0005730 nucleolus C
NAS
DmeFBgn0010278
GO:0005829 cytosol C
IDA
SpoSPBC609.05
GO:0031298 replication fork protection complex C
IDA
SceS000004534
GO:0035101 FACT complex C
IDA
AthAt3g28730
DmeFBgn0010278
SceS000004534
SpoSPBC609.05
IGI
SceS000004534
IPI
SceS000004534
TAS
DmeFBgn0010278
GO:0043596 nuclear replication fork C
ISS
SpoSPBC609.05
GO:0000217 DNA secondary structure binding F
ISS
DmeFBgn0010278
GO:0003674 molecular_function F
ND
MmuMGI:107912
GO:0003677 DNA binding F
ISS
SpoSPBC609.05
GO:0003682 chromatin binding F
IDA
SceS000004534
GO:0003697 single-stranded DNA binding F
ISS
DmeFBgn0010278
PfaPF14_0393
NAS
DmeFBgn0010278
GO:0003700 transcription factor activity F
ISS
AthAt3g28730
GO:0003711 transcription elongation regulator
activity		 F
RCA
SceS000004534
GO:0003727 single-stranded RNA binding F
NAS
DmeFBgn0010278
GO:0005515 protein binding F
IPI
DmeFBgn0010278
SpoSPBC609.05
GO:0016944 RNA polymerase II transcription elongation factor
activity		 F
RCA
SceS000004534
GO:0031491 nucleosome binding F
IDA
SceS000004534
GO:0031492 nucleosomal DNA binding F
IDA
DmeFBgn0010278
GO:0042393 histone binding F
IDA
SceS000004534
GO:0043621 protein self-association F
IDA
DmeFBgn0010278
GO:0000003 reproduction P
IMP
CelWBGene00001974
WBGene00001973
GO:0000910 cytokinesis P
IMP
CelWBGene00001973
GO:0001672 regulation of chromatin assembly or
disassembly		 P
IMP
DmeFBgn0010278
GO:0002119 nematode larval development P
IMP
CelWBGene00001974
WBGene00001973
GO:0006261 DNA-dependent DNA replication P
IGI
SceS000004534
IMP
SceS000004534
SpoSPBC609.05
IPI
SceS000004534
GO:0006281 DNA repair P
IMP
SpoSPBC609.05
GO:0006334 nucleosome assembly P
ISS
SpoSPBC609.05
GO:0006351 transcription, DNA-dependent P
IMP
SpoSPBC609.05
GO:0006368 RNA elongation from RNA polymerase II
promoter		 P
ISS
SpoSPBC609.05
GO:0007059 chromosome segregation P
IMP
SpoSPBC609.05
GO:0007413 axonal fasciculation P
IMP
CelWBGene00001973
GO:0008150 biological_process P
ND
MmuMGI:107912
PfaPF14_0393
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00001973
WBGene00001974
GO:0010171 body morphogenesis P
IMP
CelWBGene00001973
GO:0010228 vegetative to reproductive phase transition of
meristem		 P
IMP
AthAt3g28730
GO:0030466 chromatin silencing at silent mating-type
cassette		 P
IMP
SpoSPBC609.05
GO:0030702 chromatin silencing at centromere P
IMP
SpoSPBC609.05
GO:0034401 regulation of transcription by chromatin
organization		 P
IC
SceS000004534
GO:0034613 cellular protein localization P
ISS
SpoSPBC609.05
GO:0034724 DNA replication-independent nucleosome
organization		 P
IDA
SceS000004534
GO:0040007 growth P
IMP
CelWBGene00001973
WBGene00001974
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00001973
WBGene00001974
GO:0040011 locomotion P
IMP
CelWBGene00001974
WBGene00001973
GO:0040018 positive regulation of multicellular organism
growth		 P
IMP
CelWBGene00001973
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00001974
GO:0043486 histone exchange P
IC
SpoSPBC609.05
GO:0045899 positive regulation of RNA polymerase II
transcriptional preinitiation complex
assembly		 P
IDA
SceS000004534
GO:0051101 regulation of DNA binding P
IMP
DmeFBgn0010278
GO:0051301 cell division P
IMP
CelWBGene00001973

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC609.05
(O94529)		 YML069W
(S000004534)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000790 nuclear chromatin C
IDA
SceS000004534
ISS
SpoSPBC609.05
GO:0005634 nucleus C
IDA
SpoSPBC609.05
GO:0005658 alpha DNA polymerase:primase complex C
IDA
SceS000004534
GO:0005829 cytosol C
IDA
SpoSPBC609.05
GO:0031298 replication fork protection complex C
IDA
SceS000004534
GO:0035101 FACT complex C
IDA
SceS000004534
SpoSPBC609.05
IGI
SceS000004534
IPI
SceS000004534
GO:0043596 nuclear replication fork C
ISS
SpoSPBC609.05
GO:0003677 DNA binding F
ISS
SpoSPBC609.05
GO:0003682 chromatin binding F
IDA
SceS000004534
GO:0003711 transcription elongation regulator
activity		 F
RCA
SceS000004534
GO:0005515 protein binding F
IPI
SpoSPBC609.05
GO:0016944 RNA polymerase II transcription elongation factor
activity		 F
RCA
SceS000004534
GO:0031491 nucleosome binding F
IDA
SceS000004534
GO:0042393 histone binding F
IDA
SceS000004534
GO:0006261 DNA-dependent DNA replication P
IGI
SceS000004534
IMP
SceS000004534
SpoSPBC609.05
IPI
SceS000004534
GO:0006281 DNA repair P
IMP
SpoSPBC609.05
GO:0006334 nucleosome assembly P
ISS
SpoSPBC609.05
GO:0006351 transcription, DNA-dependent P
IMP
SpoSPBC609.05
GO:0006368 RNA elongation from RNA polymerase II
promoter		 P
ISS
SpoSPBC609.05
GO:0007059 chromosome segregation P
IMP
SpoSPBC609.05
GO:0030466 chromatin silencing at silent mating-type
cassette		 P
IMP
SpoSPBC609.05
GO:0030702 chromatin silencing at centromere P
IMP
SpoSPBC609.05
GO:0034401 regulation of transcription by chromatin
organization		 P
IC
SceS000004534
GO:0034613 cellular protein localization P
ISS
SpoSPBC609.05
GO:0034724 DNA replication-independent nucleosome
organization		 P
IDA
SceS000004534
GO:0043486 histone exchange P
IC
SpoSPBC609.05
GO:0045899 positive regulation of RNA polymerase II
transcriptional preinitiation complex
assembly		 P
IDA
SceS000004534

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Query species:

Include wild-cards:   

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GO info in one table:

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