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Search term: YML105C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SEC65
SGD link S000004573
Alternative ID YML105C
Description Subunit of the signal recognition particle (SRP), involved in protein targeting to the ER; interacts with Srp54p; homolog of mammalian SRP19
Synonyms YML105C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3198 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Signal recognition particle, subunit Srp19

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g48160 GI:15221088
Caenorhabditis elegans (Cel) CE27426 GI:17507249
Drosophila melanogaster (Dme) 7295253 GI:7295253
Homo sapiens (Hsa) Hs4507213
(SRP19)
GI:4507213 P09132
Saccharomyces cerevisiae (Sce) YML105c
(S000004573)
GI:6323531 P29478
Schizosaccharomyces pombe (Spo) SPCC126.15c GI:19075958 O94407
Encephalitozoon cuniculi (Ecu) ECU08g0800 GI:19173407 Q8SRC3


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPCC126.15c
GO:0005730 nucleolus C
IDA
HsaSRP19
GO:0005786 signal recognition particle, endoplasmic reticulum
targeting
C
IDA
HsaSRP19
SceS000004573
IMP
SceS000004573
ISS
AthAt1g48160
SceS000004573
SpoSPCC126.15c
GO:0005829 cytosol C
IDA
SpoSPCC126.15c
GO:0005048 signal sequence binding F
RCA
SceS000004573
GO:0008312 7S RNA binding F
IDA
HsaSRP19
SceS000004573
ISS
AthAt1g48160
GO:0042277 peptide binding F
RCA
SceS000004573
GO:0006461 protein complex assembly P
RCA
SceS000004573
GO:0006605 protein targeting P
ISS
AthAt1g48160
GO:0006613 cotranslational protein targeting to
membrane
P
TAS
HsaSRP19
GO:0006617 SRP-dependent cotranslational protein targeting to
membrane, signal sequence recognition
P
IMP
SceS000004573
ISS
SpoSPCC126.15c
GO:0042493 response to drug P
IDA
HsaSRP19
GO:0045047 protein targeting to ER P
IMP
SceS000004573

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
31819

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) sec65
(SPCC126.15c)
GI:19075958 O94407
Saccharomyces cerevisiae (Sce) SEC65
(S000004573)
GI:6323531 P29478
Kluyveromyces lactis (Kla) SC65_KLULA GI:50306359
Eremothecium gossypii (Ego) AGOS_AER289W GI:45190892
Magnaporthe grisea (Mgr) MGG_03961 GI:39943900
Neurospora crassa (Ncr) NCU03485.1 GI:32404260


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPCC126.15c
GO:0005786 signal recognition particle, endoplasmic reticulum
targeting
C
IDA
SceS000004573
IMP
SceS000004573
ISS
SceS000004573
SpoSPCC126.15c
GO:0005829 cytosol C
IDA
SpoSPCC126.15c
GO:0005048 signal sequence binding F
RCA
SceS000004573
GO:0008312 7S RNA binding F
IDA
SceS000004573
GO:0042277 peptide binding F
RCA
SceS000004573
GO:0006461 protein complex assembly P
RCA
SceS000004573
GO:0006617 SRP-dependent cotranslational protein targeting to
membrane, signal sequence recognition
P
IMP
SceS000004573
ISS
SpoSPCC126.15c
GO:0045047 protein targeting to ER P
IMP
SceS000004573

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1954

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga12237 ENSANGP00000013412
Anopheles gambiae (Aga) aga2352 ENSANGP00000021817
Ashbya gossypii (Ago) ago2791 AER289W
Arabidopsis thaliana (Ath) ath4078 At1g48160.1
Caenorhabditis elegans (Cel) cel8442 F37F2.2
(CE32185;
WBGene00018159)
Candida glabrata (Cgl) cgl3277 CAGL0J06578g
Cryptococcus neoformans (Cne) cne3972 185.m02570
Dictyostelium discoideum (Ddi) ddi2315 DDB0203118
Debaryomyces hansenii (Dha) dha4744 DEHA0F08184g
Drosophila melanogaster (Dme) dme8359 CG4457-PA
(FBgn0015298)
Danio rerio (Dre) dre25376 ENSDARP00000040624
Encephalitozoon cuniculi (Ecu) ecu238 19173407
Takifugu rubripes (Fru) fru30997 SINFRUP00000163274
Gallus gallus (Gga) gga4302 ENSGALP00000000293
(SRP19)
Homo sapiens (Hsa) hsa25588 ENSP00000282999
(SRP19)
P09132
Kluyveromyces lactis (Kla) kla2152 KLLA0D01925g
Mus musculus (Mmu) mmu12474 ENSMUSP00000072386
(MGI:1913634)
Q9CRF7
Neurospora crassa (Ncr) ncr3377 NCU03485.2
Oryza sativa (Osa) osa1589 1929.m00183
Oryza sativa (Osa) osa23199 3724.m00173
Oryza sativa (Osa) osa23200 3724.m00206
Plasmodium falciparum (Pfa) pfa4943 PFL0785c
Rattus norvegicus (Rno) rno13922 ENSRNOP00000027418
(RGD:1308437)
B2RZ66
Saccharomyces cerevisiae (Sce) sce4714 YML105C
(S000004573)
Schizosaccharomyces pombe (Spo) spo3845 SPCC126.15c O94407
Yarrowia lipolytica (Yli) yli6251 YALI0F21505g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPCC126.15c
GO:0005730 nucleolus C
ISO
MmuMGI:1913634
GO:0005786 signal recognition particle, endoplasmic reticulum
targeting
C
IDA
SceS000004573
IMP
SceS000004573
ISS
AthAt1g48160
DmeFBgn0015298
SceS000004573
SpoSPCC126.15c
GO:0005829 cytosol C
IDA
SpoSPCC126.15c
GO:0003674 molecular_function F
ND
MmuMGI:1913634
GO:0005048 signal sequence binding F
RCA
SceS000004573
GO:0008312 7S RNA binding F
IDA
SceS000004573
ISS
AthAt1g48160
DmeFBgn0015298
NAS
DmeFBgn0015298
GO:0042277 peptide binding F
RCA
SceS000004573
GO:0000003 reproduction P
IMP
CelWBGene00018159
GO:0006461 protein complex assembly P
RCA
SceS000004573
GO:0006605 protein targeting P
ISS
AthAt1g48160
GO:0006614 SRP-dependent cotranslational protein targeting to
membrane
P
ISS
DmeFBgn0015298
GO:0006617 SRP-dependent cotranslational protein targeting to
membrane, signal sequence recognition
P
IMP
SceS000004573
ISS
PfaPFL0785c
SpoSPCC126.15c
GO:0008150 biological_process P
ND
MmuMGI:1913634
GO:0045047 protein targeting to ER P
IMP
SceS000004573

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPCC126.15c
(O94407)
YML105C
(S000004573)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPCC126.15c
GO:0005786 signal recognition particle, endoplasmic reticulum
targeting
C
IDA
SceS000004573
IMP
SceS000004573
ISS
SceS000004573
SpoSPCC126.15c
GO:0005829 cytosol C
IDA
SpoSPCC126.15c
GO:0005048 signal sequence binding F
RCA
SceS000004573
GO:0008312 7S RNA binding F
IDA
SceS000004573
GO:0042277 peptide binding F
RCA
SceS000004573
GO:0006461 protein complex assembly P
RCA
SceS000004573
GO:0006617 SRP-dependent cotranslational protein targeting to
membrane, signal sequence recognition
P
IMP
SceS000004573
ISS
SpoSPCC126.15c
GO:0045047 protein targeting to ER P
IMP
SceS000004573

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s.khadayate@ucl.ac.uk