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Search term: YML106W


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name URA5
SGD link S000004574
Alternative ID YML106W
Description Major orotate phosphoribosyltransferase (OPRTase) isozyme that catalyzes the fifth enzymatic step in de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate; minor OPRTase encoded by URA10
Synonyms YML106W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1377 -CDHYP-

KOGs classification KOGs description
METABOLISM Uridine 5'- monophosphate synthase/orotate phosphoribosyltransferase

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE00638
(WBGene00011559)
GI:17554964 Q18516
Caenorhabditis elegans (Cel) CE18143
(WBGene00020036)
GI:17508631 O61790
Drosophila melanogaster (Dme) 7300695
(FBgn0003257)
GI:17933654
Homo sapiens (Hsa) Hs4507835
(UMPS)
GI:4507835 P11172
Saccharomyces cerevisiae (Sce) YEL021w
(S000000747)
GI:6320814 P03962
Saccharomyces cerevisiae (Sce) YML106w
(S000004574)
GI:6323530 P13298
Saccharomyces cerevisiae (Sce) YMR271c
(S000004884)
GI:6323927 P30402
Schizosaccharomyces pombe (Spo) SPBC725.15 GI:19112287 O94331
Schizosaccharomyces pombe (Spo) SPCC330.05c GI:19075205 P14965


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005625 soluble fraction C
IDA
SceS000000747
GO:0005634 nucleus C
IDA
HsaUMPS
SceS000004574
SpoSPBC725.15
SPCC330.05c
ISS
SpoSPBC725.15
GO:0005737 cytoplasm C
IDA
CelWBGene00011559
HsaUMPS
SceS000004884
S000004574
ISS
SpoSPBC725.15
GO:0005829 cytosol C
IDA
SceS000000747
SpoSPCC330.05c
SPBC725.15
GO:0005875 microtubule associated complex C
IDA
DmeFBgn0003257
GO:0004588 orotate phosphoribosyltransferase
activity
F
IDA
HsaUMPS
SceS000004574
IGI
SceS000004884
IMP
DmeFBgn0003257
SceS000004574
S000004884
ISA
SceS000004884
ISS
DmeFBgn0003257
SpoSPBC725.15
GO:0004590 orotidine-5'-phosphate decarboxylase
activity
F
IDA
HsaUMPS
SceS000000747
IGI
SpoSPCC330.05c
IMP
DmeFBgn0003257
SceS000000747
ISS
DmeFBgn0003257
GO:0000003 reproduction P
IMP
CelWBGene00011559
GO:0006207 'de novo' pyrimidine base biosynthetic
process
P
IC
DmeFBgn0003257
IGI
SceS000004884
SpoSPCC330.05c
IMP
SceS000004574
S000000747
ISS
SpoSPBC725.15
NAS
DmeFBgn0003257
GO:0006222 UMP biosynthetic process P
IDA
HsaUMPS
SceS000000747
IMP
SceS000000747
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00020036
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000004574
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00011559
GO:0046132 pyrimidine ribonucleoside biosynthetic
process
P
IDA
SceS000004574
IGI
SceS000004884
IMP
SceS000004884
S000004574

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
6561

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) ura5
(SPBC725.15)
GI:19112287 O94331
Saccharomyces cerevisiae (Sce) URA5
(S000004574)
GI:6323530 P13298
Kluyveromyces lactis (Kla) PYRE_KLULA GI:50306357
Eremothecium gossypii (Ego) AGOS_AER290C GI:45190893
Magnaporthe grisea (Mgr) MGG_07135 GI:39971639
Neurospora crassa (Ncr) NCU05290.1 GI:32408331
Plasmodium falciparum (Pfa) PFE0630c GI:124506173


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000004574
SpoSPBC725.15
ISS
SpoSPBC725.15
GO:0005737 cytoplasm C
IDA
SceS000004574
ISS
SpoSPBC725.15
GO:0005829 cytosol C
IDA
SpoSPBC725.15
GO:0004588 orotate phosphoribosyltransferase
activity
F
IDA
SceS000004574
IMP
SceS000004574
ISS
PfaPFE0630c
SpoSPBC725.15
GO:0006207 'de novo' pyrimidine base biosynthetic
process
P
IMP
SceS000004574
ISS
SpoSPBC725.15
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000004574
GO:0046132 pyrimidine ribonucleoside biosynthetic
process
P
IDA
SceS000004574
IMP
SceS000004574

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_556

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga6697 ENSANGP00000011669
Ashbya gossypii (Ago) ago2447 AEL059W
Ashbya gossypii (Ago) ago2792 AER290C
Arabidopsis thaliana (Ath) ath16812 At3g54470.1
Caenorhabditis elegans (Cel) cel13925 R12E2.11
(CE18143;
WBGene00020036)
Caenorhabditis elegans (Cel) cel14847 T07C4.1
(CE00638;
WBGene00011559)
Candida glabrata (Cgl) cgl2655 CAGL0I03080g
Candida glabrata (Cgl) cgl3278 CAGL0J06600g
Cryptococcus neoformans (Cne) cne4459 177.m03212
Dictyostelium discoideum (Ddi) ddi12394 DDB0214958
Debaryomyces hansenii (Dha) dha554 DEHA0A12419g
Debaryomyces hansenii (Dha) dha4743 DEHA0F08162g
Drosophila melanogaster (Dme) dme13624 CG3593-PA
(FBgn0003257)
Danio rerio (Dre) dre29831 ENSDARP00000035728
(zgc:55702)
Q7ZVR7
Escherichia coli (Eco) eco3522 16131513
Takifugu rubripes (Fru) fru15295 SINFRUP00000155998
Takifugu rubripes (Fru) fru15296 SINFRUP00000172271
Gallus gallus (Gga) gga21864 ENSGALP00000019192
(UMPS)
Q5ZMR2
Homo sapiens (Hsa) hsa23042 ENSP00000232607
(UMPS)
P11172-1
Homo sapiens (Hsa) hsa23043 ENSP00000341587
Kluyveromyces lactis (Kla) kla2151 KLLA0D01903g
Kluyveromyces lactis (Kla) kla3980 KLLA0E22902g
Mus musculus (Mmu) mmu10248 ENSMUSP00000023510
(MGI:1298388)
P13439
Neurospora crassa (Ncr) ncr3380 NCU03488.2
Neurospora crassa (Ncr) ncr5135 NCU05290.2
Oryza sativa (Osa) osa28797 4208.m00164
Oryza sativa (Osa) osa28801 4208.m00165
Plasmodium falciparum (Pfa) pfa3576 PFE0630c
Rattus norvegicus (Rno) rno7310 ENSRNOP00000002450
(RGD:1311908)
Q4QQS7
Saccharomyces cerevisiae (Sce) sce1644 YEL021W
(S000000747)
Saccharomyces cerevisiae (Sce) sce4715 YML106W
(S000004574)
Saccharomyces cerevisiae (Sce) sce5043 YMR271C
(S000004884)
Schizosaccharomyces pombe (Spo) spo2504 SPBC725.15 O94331
Schizosaccharomyces pombe (Spo) spo3632 SPCC330.05c P14965
Yarrowia lipolytica (Yli) yli4960 YALI0E26741g
Yarrowia lipolytica (Yli) yli6252 YALI0F21527g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt3g54470
MmuMGI:1298388
GO:0005625 soluble fraction C
IDA
SceS000000747
GO:0005634 nucleus C
IDA
SceS000004574
SpoSPBC725.15
SPCC330.05c
ISS
SpoSPBC725.15
GO:0005737 cytoplasm C
IDA
CelWBGene00011559
SceS000004884
S000004574
ISS
SpoSPBC725.15
GO:0005829 cytosol C
IDA
SceS000000747
SpoSPCC330.05c
SPBC725.15
GO:0005875 microtubule associated complex C
IDA
DmeFBgn0003257
GO:0003674 molecular_function F
ND
MmuMGI:1298388
GO:0004588 orotate phosphoribosyltransferase
activity
F
IDA
SceS000004574
IGI
AthAt3g54470
SceS000004884
IMP
DmeFBgn0003257
SceS000004574
S000004884
ISA
SceS000004884
ISS
AthAt3g54470
DmeFBgn0003257
PfaPFE0630c
SpoSPBC725.15
GO:0004590 orotidine-5'-phosphate decarboxylase
activity
F
IDA
SceS000000747
IGI
AthAt3g54470
SpoSPCC330.05c
IMP
DmeFBgn0003257
SceS000000747
ISS
AthAt3g54470
DmeFBgn0003257
GO:0000003 reproduction P
IMP
CelWBGene00011559
GO:0006207 'de novo' pyrimidine base biosynthetic
process
P
IC
DmeFBgn0003257
IGI
SceS000004884
SpoSPCC330.05c
IMP
SceS000004574
S000000747
ISS
SpoSPBC725.15
NAS
DmeFBgn0003257
GO:0006222 UMP biosynthetic process P
IDA
SceS000000747
IMP
SceS000000747
GO:0008150 biological_process P
ND
MmuMGI:1298388
GO:0009116 nucleoside metabolic process P
ISS
AthAt3g54470
GO:0009220 pyrimidine ribonucleotide biosynthetic
process
P
IGI
AthAt3g54470
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00020036
GO:0016036 cellular response to phosphate
starvation
P
IEP
AthAt3g54470
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000004574
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00011559
GO:0046132 pyrimidine ribonucleoside biosynthetic
process
P
IDA
SceS000004574
IGI
SceS000004884
IMP
SceS000004884
S000004574
GO:0046686 response to cadmium ion P
IEP
AthAt3g54470

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPBC725.15
(O94331)
YML106W
(S000004574)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000004574
SpoSPBC725.15
ISS
SpoSPBC725.15
GO:0005737 cytoplasm C
IDA
SceS000004574
ISS
SpoSPBC725.15
GO:0005829 cytosol C
IDA
SpoSPBC725.15
GO:0004588 orotate phosphoribosyltransferase
activity
F
IDA
SceS000004574
IMP
SceS000004574
ISS
SpoSPBC725.15
GO:0006207 'de novo' pyrimidine base biosynthetic
process
P
IMP
SceS000004574
ISS
SpoSPBC725.15
GO:0018193 peptidyl-amino acid modification P
RCA
SceS000004574
GO:0046132 pyrimidine ribonucleoside biosynthetic
process
P
IDA
SceS000004574
IMP
SceS000004574

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Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk