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Search term: YML130C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ERO1
SGD link S000004599
Alternative ID YML130C
Description Thiol oxidase required for oxidative protein folding in the endoplasmic reticulum
Synonyms YML130C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

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Search for GO info:  

GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2608 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALINGCELLULAR PROCESSES AND SIGNALING Endoplasmic reticulum membrane-associated oxidoreductin involved in disulfide bond formation

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g72280 GI:15218421
Arabidopsis thaliana (Ath) At2g38960 GI:15224988
Caenorhabditis elegans (Cel) CE28787 GI:17510823
Drosophila melanogaster (Dme) 7292447 GI:6456532
Homo sapiens (Hsa) Hs7657069
(ERO1L)
GI:7657069 Q96HE7
Homo sapiens (Hsa) Hs9845249 GI:9845249
Saccharomyces cerevisiae (Sce) YML130c
(S000004599)
GI:6323505 Q03103
Schizosaccharomyces pombe (Spo) SPBC4F6.16c GI:19112908 O74401
Schizosaccharomyces pombe (Spo) SPCC1450.14c GI:19075813 Q9Y7P1
Encephalitozoon cuniculi (Ecu) ECU04g0170 GI:19074095 Q8SVY0


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005624 membrane fraction C
TAS
HsaERO1L
GO:0005783 endoplasmic reticulum C
IDA
AthAt2g38960
At1g72280
HsaERO1L
SceS000004599
SpoSPCC1450.14c
SPBC4F6.16c
GO:0005789 endoplasmic reticulum membrane C
IDA
SpoSPCC1450.14c
SPBC4F6.16c
GO:0005792 microsome C
TAS
HsaERO1L
GO:0009055 electron carrier activity F
IMP
SceS000004599
ISS
SceS000004599
GO:0015035 protein disulfide oxidoreductase
activity
F
IGI
SpoSPBC4F6.16c
SPCC1450.14c
GO:0016491 oxidoreductase activity F
IDA
HsaERO1L
GO:0016972 thiol oxidase activity F
IDA
SceS000004599
GO:0006457 protein folding P
IC
SpoSPBC4F6.16c
IMP
SceS000004599
TAS
HsaERO1L
GO:0006464 protein modification process P
TAS
HsaERO1L
GO:0006467 protein thiol-disulfide exchange P
IGI
SpoSPBC4F6.16c
SPCC1450.14c
IMP
SceS000004599
GO:0009266 response to temperature stimulus P
TAS
HsaERO1L
GO:0033554 cellular response to stress P
IEP
SpoSPBC4F6.16c
GO:0034975 protein folding in endoplasmic
reticulum
P
IC
SpoSPBC4F6.16c
SPCC1450.14c
GO:0051085 chaperone mediated protein folding requiring
cofactor
P
IDA
HsaERO1L

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
49392

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) ERO1L GI:7657069 Q96HE7
Pan troglodytes (Ptr) ERO1L GI:114653045
Canis familiaris (Cfa) ERO1L GI:73963815
Mus musculus (Mmu) Ero1l
(MGI:1354385)
GI:7657067 Q3TXL0
Rattus norvegicus (Rno) Ero1l
(RGD:621713)
GI:19924061
Gallus gallus (Gga) ERO1L GI:118092359
Caenorhabditis elegans (Cel) ero-1
(CE33847;
WBGene00001334)
GI:71993035
Schizosaccharomyces pombe (Spo) ero12
(SPCC1450.14c)
GI:19075813 Q9Y7P1
Saccharomyces cerevisiae (Sce) ERO1
(S000004599)
GI:6323505 Q03103
Kluyveromyces lactis (Kla) KLLA0D10241g GI:50307077
Eremothecium gossypii (Ego) AGOS_ADL348W GI:45187524
Magnaporthe grisea (Mgr) MGG_00683 GI:145611046
Neurospora crassa (Ncr) NCU02074.1 GI:32417572
Arabidopsis thaliana (Ath) AERO2 GI:42571127


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005624 membrane fraction C
TAS
HsaERO1L
GO:0005783 endoplasmic reticulum C
IDA
AthAERO2
HsaERO1L
SceS000004599
SpoSPCC1450.14c
GO:0005789 endoplasmic reticulum membrane C
IDA
SpoSPCC1450.14c
GO:0005792 microsome C
TAS
HsaERO1L
GO:0030176 integral to endoplasmic reticulum
membrane
C
ISO
MmuMGI:1354385
GO:0009055 electron carrier activity F
IMP
SceS000004599
ISS
SceS000004599
GO:0015035 protein disulfide oxidoreductase
activity
F
IGI
SpoSPCC1450.14c
GO:0016491 oxidoreductase activity F
IDA
HsaERO1L
MmuMGI:1354385
GO:0016972 thiol oxidase activity F
IDA
SceS000004599
GO:0000003 reproduction P
IMP
CelWBGene00001334
GO:0002119 nematode larval development P
IMP
CelWBGene00001334
GO:0006457 protein folding P
IDA
MmuMGI:1354385
IMP
SceS000004599
ISO
MmuMGI:1354385
TAS
HsaERO1L
GO:0006464 protein modification process P
TAS
HsaERO1L
GO:0006467 protein thiol-disulfide exchange P
IGI
SpoSPCC1450.14c
IMP
SceS000004599
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00001334
GO:0009266 response to temperature stimulus P
TAS
HsaERO1L
GO:0030968 endoplasmic reticulum unfolded protein
response
P
IDA
MmuMGI:1354385
GO:0034975 protein folding in endoplasmic
reticulum
P
IC
SpoSPCC1450.14c
GO:0040007 growth P
IMP
CelWBGene00001334
GO:0050873 brown fat cell differentiation P
IDA
MmuMGI:1354385
GO:0051085 chaperone mediated protein folding requiring
cofactor
P
IDA
HsaERO1L

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_773

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga5043 ENSANGP00000016852
Ashbya gossypii (Ago) ago1392 ADL348W
Arabidopsis thaliana (Ath) ath6514 At1g72280.1
Arabidopsis thaliana (Ath) ath11008 At2g38960.1
Arabidopsis thaliana (Ath) ath11009 At2g38960.2
Caenorhabditis elegans (Cel) cel17535 Y105E8B.8a
(CE33847;
WBGene00001334)
Caenorhabditis elegans (Cel) cel17536 Y105E8B.8b
(CE34224)
Candida glabrata (Cgl) cgl2364 CAGL0H06919g
Cryptococcus neoformans (Cne) cne4476 177.m03231
Dictyostelium discoideum (Ddi) ddi7196 DDB0188144
Debaryomyces hansenii (Dha) dha174 DEHA0A03905g
Drosophila melanogaster (Dme) dme7914 CG1333-PA
(FBgn0028736)
Drosophila melanogaster (Dme) dme7915 CG1333-PB
(FBgn0028736)
Danio rerio (Dre) dre14178 ENSDARP00000006444
Danio rerio (Dre) dre438 ENSDARP00000015478
Danio rerio (Dre) dre14177 ENSDARP00000025911
Danio rerio (Dre) dre14175 ENSDARP00000032925
Danio rerio (Dre) dre14176 ENSDARP00000049447
(zgc:153032)
Q08CJ0
Encephalitozoon cuniculi (Ecu) ecu733 19074095
Takifugu rubripes (Fru) fru20716 SINFRUP00000145011
Takifugu rubripes (Fru) fru20719 SINFRUP00000166866
Takifugu rubripes (Fru) fru20718 SINFRUP00000168181
Takifugu rubripes (Fru) fru20717 SINFRUP00000175561
Gallus gallus (Gga) gga14983 ENSGALP00000017597
(ERO1LB)
Gallus gallus (Gga) gga14984 ENSGALP00000017598
Gallus gallus (Gga) gga20081 ENSGALP00000020229
(ERO1L)
Gallus gallus (Gga) gga20082 ENSGALP00000020230
Gallus gallus (Gga) gga20084 ENSGALP00000020232
Homo sapiens (Hsa) hsa3274 ENSP00000264181
(ERO1LB)
Q5TAE8
Homo sapiens (Hsa) hsa9536 ENSP00000346447
Homo sapiens (Hsa) hsa3276 ENSP00000346635
(ERO1LB)
Q86YB8
Homo sapiens (Hsa) hsa9535 ENSP00000352044
(ERO1L)
Homo sapiens (Hsa) hsa3275 ENSP00000354221
Kluyveromyces lactis (Kla) kla2516 KLLA0D10241g
Mus musculus (Mmu) mmu7984 ENSMUSP00000022378
(MGI:1354385)
Q8R180
Neurospora crassa (Ncr) ncr2016 NCU02074.2
Oryza sativa (Osa) osa25568 3894.m00191
Oryza sativa (Osa) osa86939 9220.m00128
Oryza sativa (Osa) osa87713 9238.m00125
Plasmodium falciparum (Pfa) pfa702 PF11_0251
Rattus norvegicus (Rno) rno13502 ENSRNOP00000003526
(RGD:1563548)
Rattus norvegicus (Rno) rno11147 ENSRNOP00000009404
(RGD:621713)
Saccharomyces cerevisiae (Sce) sce4740 YML130C
(S000004599)
Schizosaccharomyces pombe (Spo) spo43 SPBC4F6.16c O74401
Schizosaccharomyces pombe (Spo) spo4045 SPCC1450.14c Q9Y7P1
Yarrowia lipolytica (Yli) yli3106 YALI0D09603g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
AthAt2g38960
At1g72280
SceS000004599
SpoSPCC1450.14c
SPBC4F6.16c
ISS
PfaPF11_0251
GO:0005789 endoplasmic reticulum membrane C
IDA
SpoSPCC1450.14c
SPBC4F6.16c
GO:0030176 integral to endoplasmic reticulum
membrane
C
ISO
MmuMGI:1354385
GO:0009055 electron carrier activity F
IMP
SceS000004599
ISS
SceS000004599
GO:0015035 protein disulfide oxidoreductase
activity
F
IGI
SpoSPBC4F6.16c
SPCC1450.14c
GO:0016491 oxidoreductase activity F
IDA
MmuMGI:1354385
ISS
PfaPF11_0251
GO:0016972 thiol oxidase activity F
IDA
SceS000004599
GO:0000003 reproduction P
IMP
CelWBGene00001334
GO:0002119 nematode larval development P
IMP
CelWBGene00001334
GO:0006457 protein folding P
IC
SpoSPBC4F6.16c
IDA
MmuMGI:1354385
IMP
SceS000004599
ISO
MmuMGI:1354385
ISS
PfaPF11_0251
GO:0006467 protein thiol-disulfide exchange P
IGI
SpoSPBC4F6.16c
SPCC1450.14c
IMP
SceS000004599
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00001334
GO:0030968 endoplasmic reticulum unfolded protein
response
P
IDA
MmuMGI:1354385
GO:0033554 cellular response to stress P
IEP
SpoSPBC4F6.16c
GO:0034975 protein folding in endoplasmic
reticulum
P
IC
SpoSPBC4F6.16c
SPCC1450.14c
GO:0040007 growth P
IMP
CelWBGene00001334
GO:0050873 brown fat cell differentiation P
IDA
MmuMGI:1354385

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Curated yeast ortholog results:

S. pombe
systematic ID
S. cerevisiae
systematic ID
SPCC1450.14c
(Q9Y7P1)
YML130C
(S000004599)
SPBC4F6.16c
(O74401)
YML130C
(S000004599)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
SceS000004599
SpoSPCC1450.14c
SPBC4F6.16c
GO:0005789 endoplasmic reticulum membrane C
IDA
SpoSPCC1450.14c
SPBC4F6.16c
GO:0009055 electron carrier activity F
IMP
SceS000004599
ISS
SceS000004599
GO:0015035 protein disulfide oxidoreductase
activity
F
IGI
SpoSPBC4F6.16c
SPCC1450.14c
GO:0016972 thiol oxidase activity F
IDA
SceS000004599
GO:0006457 protein folding P
IC
SpoSPBC4F6.16c
IMP
SceS000004599
GO:0006467 protein thiol-disulfide exchange P
IGI
SpoSPBC4F6.16c
SPCC1450.14c
IMP
SceS000004599
GO:0033554 cellular response to stress P
IEP
SpoSPBC4F6.16c
GO:0034975 protein folding in endoplasmic
reticulum
P
IC
SpoSPBC4F6.16c
SPCC1450.14c

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Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk