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Search term: YMR076C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PDS5
SGD link S000004681
Alternative ID YMR076C
Description Protein required for establishment and maintenance of sister chromatid condensation and cohesion, colocalizes with cohesin on chromosomes, may function as a protein-protein interaction scaffold; also required during meiosis
Synonyms YMR076C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1525 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Sister chromatid cohesion complex Cohesin, subunit PDS5

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g15940 GI:15218375
Arabidopsis thaliana (Ath) At1g77600 GI:15224014
Arabidopsis thaliana (Ath) At1g80810 GI:15220831
Arabidopsis thaliana (Ath) At4g31880 GI:15236553
Arabidopsis thaliana (Ath) At5g10950 GI:15238906
Arabidopsis thaliana (Ath) At5g47690 GI:15240802
Caenorhabditis elegans (Cel) CE18829 GI:17553914
Drosophila melanogaster (Dme) 7303538
(pds5)		 GI:20129889
Homo sapiens (Hsa) Hs22040928 GI:22040928
Homo sapiens (Hsa) Hs7657269
(PDS5B)		 GI:7657269 Q9NTI5
Homo sapiens (Hsa) Hs7705288 GI:7705288
Saccharomyces cerevisiae (Sce) YMR076c
(S000004681)		 GI:6323722 Q04264
Schizosaccharomyces pombe (Spo) SPAC110.02 GI:19114447 Q9HFF5


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000785 chromatin C
IDA
HsaPDS5B
GO:0000794 condensed nuclear chromosome C
IC
SpoSPAC110.02
IDA
SceS000004681
GO:0005575 cellular_component C
ND
AthAt1g77600
At1g80810
GO:0005634 nucleus C
IDA
AthAt5g47690
Dmepds5
ISS
HsaPDS5B
GO:0005700 polytene chromosome C
IDA
Dmepds5
GO:0005739 mitochondrion C
IDA
AthAt5g47690
GO:0005829 cytosol C
IDA
AthAt4g31880
At5g10950
GO:0008278 cohesin complex C
IDA
Dmepds5
GO:0009507 chloroplast C
IDA
AthAt5g47690
At4g31880
GO:0030892 mitotic cohesin complex C
IGI
SpoSPAC110.02
GO:0003674 molecular_function F
ND
AthAt5g10950
GO:0005198 structural molecule activity F
ISS
SceS000004681
GO:0005515 protein binding F
IPI
HsaPDS5B
SpoSPAC110.02
GO:0005524 ATP binding F
TAS
HsaPDS5B
GO:0042802 identical protein binding F
IPI
HsaPDS5B
GO:0006302 double-strand break repair P
IMP
SceS000004681
GO:0006974 response to DNA damage stimulus P
IMP
SpoSPAC110.02
GO:0007059 chromosome segregation P
IMP
Dmepds5
SpoSPAC110.02
GO:0007062 sister chromatid cohesion P
IGI
SpoSPAC110.02
IMP
Dmepds5
GO:0007064 mitotic sister chromatid cohesion P
IMP
HsaPDS5B
SceS000004681
GO:0007076 mitotic chromosome condensation P
IMP
SceS000004681
GO:0007126 meiosis P
IMP
SceS000004681
GO:0007129 synapsis P
IMP
SceS000004681
GO:0008150 biological_process P
ND
AthAt5g10950
At5g47690
At1g80810
At1g15940
At1g77600
GO:0008283 cell proliferation P
TAS
HsaPDS5B
GO:0008285 negative regulation of cell proliferation P
IDA
HsaPDS5B
GO:0030717 karyosome formation P
IMP
Dmepds5
GO:0042127 regulation of cell proliferation P
IDA
HsaPDS5B
GO:0051455 attachment of spindle microtubules to kinetochore
involved in homologous chromosome
segregation		 P
IMP
SpoSPAC110.02

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
41001

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) PDS5B GI:7657269 Q9NTI5
Pan troglodytes (Ptr) PDS5B GI:114649463
Canis familiaris (Cfa) PDS5B GI:73993417
Mus musculus (Mmu) Pds5b
(MGI:2140945)		 GI:66955886 Q4VA53
Rattus norvegicus (Rno) Pds5b GI:109494992
Gallus gallus (Gga) PDS5B GI:61098246
Drosophila melanogaster (Dme) pds5 GI:20129889
Anopheles gambiae (Aga) AgaP_AGAP010643 GI:158289697
Caenorhabditis elegans (Cel) evl-14
(CE33526;
WBGene00001352)		 GI:32565472
Schizosaccharomyces pombe (Spo) pds5
(SPAC110.02)		 GI:19114447 Q9HFF5
Saccharomyces cerevisiae (Sce) PDS5
(S000004681)		 GI:6323722 Q04264
Kluyveromyces lactis (Kla) KLLA0F25806g GI:50312391
Eremothecium gossypii (Ego) AGOS_AGL076W GI:45201020
Magnaporthe grisea (Mgr) MGG_06465 GI:39977125
Neurospora crassa (Ncr) NCU00424.1 GI:32403794
Arabidopsis thaliana (Ath) AT5G47690 GI:186530158
Arabidopsis thaliana (Ath) AT1G77600 GI:30699273
Oryza sativa (Osa) Os06g0285900 GI:115467614


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000785 chromatin C
IDA
HsaPDS5B
GO:0000794 condensed nuclear chromosome C
IC
SpoSPAC110.02
IDA
SceS000004681
GO:0005575 cellular_component C
ND
AthAt1g77600
GO:0005634 nucleus C
IDA
AthAt5g47690
Dmepds5
ISO
MmuMGI:2140945
ISS
HsaPDS5B
GO:0005700 polytene chromosome C
IDA
Dmepds5
GO:0005739 mitochondrion C
IDA
AthAt5g47690
GO:0008278 cohesin complex C
IDA
Dmepds5
GO:0009507 chloroplast C
IDA
AthAt5g47690
GO:0030892 mitotic cohesin complex C
IGI
SpoSPAC110.02
GO:0003674 molecular_function F
ND
MmuMGI:2140945
GO:0005198 structural molecule activity F
ISS
SceS000004681
GO:0005515 protein binding F
IPI
HsaPDS5B
SpoSPAC110.02
GO:0005524 ATP binding F
TAS
HsaPDS5B
GO:0042802 identical protein binding F
IPI
HsaPDS5B
GO:0000003 reproduction P
IMP
CelWBGene00001352
GO:0006302 double-strand break repair P
IMP
SceS000004681
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00001352
GO:0006974 response to DNA damage stimulus P
IMP
SpoSPAC110.02
GO:0007059 chromosome segregation P
IMP
Dmepds5
SpoSPAC110.02
GO:0007062 sister chromatid cohesion P
IGI
SpoSPAC110.02
IMP
Dmepds5
GO:0007064 mitotic sister chromatid cohesion P
IMP
CelWBGene00001352
HsaPDS5B
SceS000004681
GO:0007076 mitotic chromosome condensation P
IMP
SceS000004681
GO:0007126 meiosis P
IMP
SceS000004681
GO:0007129 synapsis P
IMP
SceS000004681
GO:0008150 biological_process P
ND
AthAt5g47690
At1g77600
GO:0008283 cell proliferation P
TAS
HsaPDS5B
GO:0008285 negative regulation of cell proliferation P
IDA
HsaPDS5B
ISO
MmuMGI:2140945
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00001352
GO:0030717 karyosome formation P
IMP
Dmepds5
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00001352
GO:0040011 locomotion P
IMP
CelWBGene00001352
GO:0040018 positive regulation of multicellular organism
growth		 P
IMP
CelWBGene00001352
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00001352
GO:0042127 regulation of cell proliferation P
IDA
HsaPDS5B
ISO
MmuMGI:2140945
GO:0051177 meiotic sister chromatid cohesion P
IMP
CelWBGene00001352
GO:0051455 attachment of spindle microtubules to kinetochore
involved in homologous chromosome
segregation		 P
IMP
SpoSPAC110.02

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1905

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga7604 ENSANGP00000016697
Ashbya gossypii (Ago) ago4235 AGL076W
Arabidopsis thaliana (Ath) ath7099 At1g77600.1
Arabidopsis thaliana (Ath) ath26653 At5g47690.1
Caenorhabditis elegans (Cel) cel11489 H38K22.1
(CE33526;
WBGene00001352)
Candida glabrata (Cgl) cgl3058 CAGL0J01507g
Cryptococcus neoformans (Cne) cne3848 185.m02432
Dictyostelium discoideum (Ddi) ddi3972 DDB0217729
Debaryomyces hansenii (Dha) dha5318 DEHA0F20966g
Drosophila melanogaster (Dme) dme4588 CG17509-PA
(FBgn0033676)
Danio rerio (Dre) dre6487 ENSDARP00000002621
Danio rerio (Dre) dre497 ENSDARP00000025451
Takifugu rubripes (Fru) fru25617 SINFRUP00000132946
Takifugu rubripes (Fru) fru6498 SINFRUP00000142443
Gallus gallus (Gga) gga18183 ENSGALP00000023059
(PDS5A)		 Q5F3V3
Gallus gallus (Gga) gga3082 ENSGALP00000027519
(PDS5B)		 Q5F3U9
Gallus gallus (Gga) gga3083 ENSGALP00000027520
(PDS5B)
Gallus gallus (Gga) gga3084 ENSGALP00000027521
Homo sapiens (Hsa) hsa24034 ENSP00000303427
(PDS5A)		 Q29RF7-1
Homo sapiens (Hsa) hsa8649 ENSP00000313851
(PDS5B)		 Q9NTI5-1
Kluyveromyces lactis (Kla) kla5229 KLLA0F25806g
Mus musculus (Mmu) mmu20150 ENSMUSP00000031104
(MGI:1918771)		 Q6A026
Mus musculus (Mmu) mmu21377 ENSMUSP00000038421
(MGI:2140945)		 Q4VA53-1
Neurospora crassa (Ncr) ncr410 NCU00424.2
Oryza sativa (Osa) osa10467 2778.m00145
Oryza sativa (Osa) osa31407 4383.m00145
Oryza sativa (Osa) osa51639 5883.m00135
Rattus norvegicus (Rno) rno7961 ENSRNOP00000001464
(RGD:1310838)		 Q6TRW4-3
Rattus norvegicus (Rno) rno10374 ENSRNOP00000003437
(RGD:1307094)		 A4L9P7
Rattus norvegicus (Rno) rno7960 ENSRNOP00000040297
(RGD:1310838)		 Q6TRW4-1
Rattus norvegicus (Rno) rno7963 ENSRNOP00000051139
Saccharomyces cerevisiae (Sce) sce4829 YMR076C
(S000004681)
Schizosaccharomyces pombe (Spo) spo110 SPAC110.02 Q9HFF5
Yarrowia lipolytica (Yli) yli4397 YALI0E12969g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000794 condensed nuclear chromosome C
IC
SpoSPAC110.02
IDA
SceS000004681
GO:0005575 cellular_component C
ND
AthAt1g77600
GO:0005634 nucleus C
IDA
AthAt5g47690
ISO
MmuMGI:2140945
GO:0005739 mitochondrion C
IDA
AthAt5g47690
GO:0009507 chloroplast C
IDA
AthAt5g47690
GO:0030892 mitotic cohesin complex C
IGI
SpoSPAC110.02
GO:0003674 molecular_function F
ND
MmuMGI:2140945
GO:0005198 structural molecule activity F
ISS
SceS000004681
GO:0005515 protein binding F
IPI
SpoSPAC110.02
GO:0000003 reproduction P
IMP
CelWBGene00001352
GO:0006302 double-strand break repair P
IMP
SceS000004681
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00001352
GO:0006974 response to DNA damage stimulus P
IMP
SpoSPAC110.02
GO:0007059 chromosome segregation P
IMP
SpoSPAC110.02
GO:0007062 sister chromatid cohesion P
IGI
SpoSPAC110.02
GO:0007064 mitotic sister chromatid cohesion P
IMP
CelWBGene00001352
SceS000004681
GO:0007076 mitotic chromosome condensation P
IMP
SceS000004681
GO:0007126 meiosis P
IMP
SceS000004681
GO:0007129 synapsis P
IMP
SceS000004681
GO:0008150 biological_process P
ND
AthAt5g47690
At1g77600
GO:0008285 negative regulation of cell proliferation P
ISO
MmuMGI:2140945
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00001352
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00001352
GO:0040011 locomotion P
IMP
CelWBGene00001352
GO:0040018 positive regulation of multicellular organism
growth		 P
IMP
CelWBGene00001352
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00001352
GO:0042127 regulation of cell proliferation P
ISO
MmuMGI:2140945
GO:0051177 meiotic sister chromatid cohesion P
IMP
CelWBGene00001352
GO:0051455 attachment of spindle microtubules to kinetochore
involved in homologous chromosome
segregation		 P
IMP
SpoSPAC110.02

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC110.02
(Q9HFF5)		 YMR076C
(S000004681)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000794 condensed nuclear chromosome C
IC
SpoSPAC110.02
IDA
SceS000004681
GO:0030892 mitotic cohesin complex C
IGI
SpoSPAC110.02
GO:0005198 structural molecule activity F
ISS
SceS000004681
GO:0005515 protein binding F
IPI
SpoSPAC110.02
GO:0006302 double-strand break repair P
IMP
SceS000004681
GO:0006974 response to DNA damage stimulus P
IMP
SpoSPAC110.02
GO:0007059 chromosome segregation P
IMP
SpoSPAC110.02
GO:0007062 sister chromatid cohesion P
IGI
SpoSPAC110.02
GO:0007064 mitotic sister chromatid cohesion P
IMP
SceS000004681
GO:0007076 mitotic chromosome condensation P
IMP
SceS000004681
GO:0007126 meiosis P
IMP
SceS000004681
GO:0007129 synapsis P
IMP
SceS000004681
GO:0051455 attachment of spindle microtubules to kinetochore
involved in homologous chromosome
segregation		 P
IMP
SpoSPAC110.02

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