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Search term: YMR080C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name NAM7
SGD link S000004685
Alternative ID YMR080C
Description ATP-dependent RNA helicase of the SFI superfamily involved in nonsense mediated mRNA decay; required for efficient translation termination at nonsense codons and targeting of NMD substrates to P-bodies; involved in telomere maintenance
Synonyms YMR080C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1802 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING RNA helicase nonsense mRNA reducing factor (pNORF1)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At5g47010 GI:15237996
Caenorhabditis elegans (Cel) CE28367
(WBGene00004880)		 GI:17510163 O76512
Drosophila melanogaster (Dme) 7292718 GI:18203558
Homo sapiens (Hsa) Hs18375673
(UPF1)		 GI:18375673 O60385
Homo sapiens (Hsa) Hs20162560 GI:20162560
Saccharomyces cerevisiae (Sce) YER176w
(S000000978)		 GI:6321024 P32644
Saccharomyces cerevisiae (Sce) YMR080c
(S000004685)		 GI:6323726 P30771
Schizosaccharomyces pombe (Spo) SPAC16C9.06c GI:19113992 Q09820
Encephalitozoon cuniculi (Ecu) ECU10g1640 GI:19074775 Q8SR02


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000785 chromatin C
IDA
HsaUPF1
GO:0005634 nucleus C
IDA
CelWBGene00004880
GO:0005737 cytoplasm C
IDA
CelWBGene00004880
SceS000004685
ISS
SpoSPAC16C9.06c
NAS
HsaUPF1
TAS
CelWBGene00004880
GO:0005829 cytosol C
IDA
SpoSPAC16C9.06c
GO:0005844 polysome C
IDA
SceS000000978
TAS
SceS000004685
GO:0005886 plasma membrane C
IDA
AthAt5g47010
GO:0003676 nucleic acid binding F
TAS
SceS000004685
GO:0003678 DNA helicase activity F
IDA
SceS000000978
GO:0003682 chromatin binding F
IDA
HsaUPF1
GO:0003723 RNA binding F
NAS
HsaUPF1
GO:0003724 RNA helicase activity F
ISS
AthAt5g47010
SceS000000978
GO:0004004 ATP-dependent RNA helicase activity F
IDA
HsaUPF1
ISS
CelWBGene00004880
SpoSPAC16C9.06c
TAS
SceS000004685
GO:0004386 helicase activity F
NAS
HsaUPF1
GO:0005515 protein binding F
IPI
CelWBGene00004880
HsaUPF1
GO:0005524 ATP binding F
IC
SpoSPAC16C9.06c
GO:0008186 RNA-dependent ATPase activity F
TAS
SceS000004685
GO:0051721 protein phosphatase 2A binding F
IPI
CelWBGene00004880
GO:0000184 nuclear-transcribed mRNA catabolic process,
nonsense-mediated decay		 P
IDA
HsaUPF1
IGI
CelWBGene00004880
IMP
HsaUPF1
ISS
SpoSPAC16C9.06c
NAS
HsaUPF1
TAS
HsaUPF1
SceS000004685
GO:0000956 nuclear-transcribed mRNA catabolic
process		 P
IMP
SceS000004685
GO:0006260 DNA replication P
IMP
HsaUPF1
GO:0006281 DNA repair P
IDA
HsaUPF1
GO:0006406 mRNA export from nucleus P
TAS
HsaUPF1
GO:0006415 translational termination P
ISS
SpoSPAC16C9.06c
RCA
SceS000004685
GO:0006417 regulation of translation P
RCA
SceS000004685
GO:0006449 regulation of translational termination P
IMP
HsaUPF1
SceS000000978
NAS
HsaUPF1
TAS
SceS000004685
GO:0006605 protein targeting P
RCA
SceS000004685
GO:0006886 intracellular protein transport P
RCA
SceS000004685
GO:0007049 cell cycle P
IMP
HsaUPF1
GO:0008298 intracellular mRNA localization P
IMP
SceS000004685
GO:0009744 response to sucrose stimulus P
IGI
AthAt5g47010
GO:0010182 sugar mediated signaling pathway P
IMP
AthAt5g47010
GO:0015031 protein transport P
RCA
SceS000004685
GO:0016246 RNA interference P
IGI
AthAt5g47010
IMP
CelWBGene00004880
GO:0016567 protein ubiquitination P
IDA
SceS000004685
IMP
SceS000004685
IPI
SceS000004685
GO:0030466 chromatin silencing at silent mating-type
cassette		 P
IGI
SceS000004685
GO:0030538 embryonic genitalia morphogenesis P
IMP
CelWBGene00004880
GO:0034613 cellular protein localization P
RCA
SceS000004685
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00004880
GO:0045184 establishment of protein localization P
RCA
SceS000004685
GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5'
exonucleolytic nonsense-mediated
decay		 P
IGI
SceS000004685
IMP
SceS000004685
GO:0071044 histone mRNA catabolic process P
IMP
HsaUPF1

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
2185

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) UPF1 GI:18375673 O60385
Pan troglodytes (Ptr) UPF1 GI:114676176
Canis familiaris (Cfa) UPF1 GI:73986070
Mus musculus (Mmu) Upf1
(MGI:107995)		 GI:13507601 Q9EPU0
Gallus gallus (Gga) UPF1 GI:118103271
Drosophila melanogaster (Dme) Upf1
(FBgn0030354)		 GI:18859757
Anopheles gambiae (Aga) AgaP_AGAP001133 GI:158302494
Caenorhabditis elegans (Cel) smg-2
(CE28367;
WBGene00004880)		 GI:17510163 O76512
Schizosaccharomyces pombe (Spo) upf1
(SPAC16C9.06c)		 GI:19113992 Q09820
Saccharomyces cerevisiae (Sce) NAM7
(S000004685)		 GI:6323726 P30771
Kluyveromyces lactis (Kla) KLLA0B06435g GI:50303751
Eremothecium gossypii (Ego) AGOS_ABR022C GI:119873835
Magnaporthe grisea (Mgr) MGG_00976 GI:39973755
Neurospora crassa (Ncr) NCU04242.1 GI:32405938
Arabidopsis thaliana (Ath) LBA1 GI:30695086
Oryza sativa (Osa) Os07g0495900 GI:115472199
Plasmodium falciparum (Pfa) PF10_0057 GI:124802033


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000785 chromatin C
IDA
HsaUPF1
GO:0005634 nucleus C
IDA
CelWBGene00004880
GO:0005737 cytoplasm C
IDA
CelWBGene00004880
SceS000004685
ISS
SpoSPAC16C9.06c
NAS
DmeFBgn0030354
HsaUPF1
TAS
CelWBGene00004880
GO:0005829 cytosol C
IDA
SpoSPAC16C9.06c
GO:0005844 polysome C
TAS
SceS000004685
GO:0005886 plasma membrane C
IDA
AthLBA1
GO:0003676 nucleic acid binding F
TAS
SceS000004685
GO:0003682 chromatin binding F
IDA
HsaUPF1
GO:0003723 RNA binding F
NAS
HsaUPF1
GO:0003724 RNA helicase activity F
ISS
AthLBA1
GO:0004004 ATP-dependent RNA helicase activity F
IDA
HsaUPF1
ISS
CelWBGene00004880
SpoSPAC16C9.06c
TAS
SceS000004685
GO:0004386 helicase activity F
ISS
DmeFBgn0030354
NAS
HsaUPF1
GO:0005515 protein binding F
IPI
CelWBGene00004880
HsaUPF1
GO:0005524 ATP binding F
IC
SpoSPAC16C9.06c
GO:0008186 RNA-dependent ATPase activity F
TAS
SceS000004685
GO:0051721 protein phosphatase 2A binding F
IPI
CelWBGene00004880
GO:0000184 nuclear-transcribed mRNA catabolic process,
nonsense-mediated decay		 P
IDA
HsaUPF1
IGI
CelWBGene00004880
IMP
DmeFBgn0030354
HsaUPF1
ISS
DmeFBgn0030354
SpoSPAC16C9.06c
NAS
DmeFBgn0030354
HsaUPF1
TAS
HsaUPF1
SceS000004685
GO:0000956 nuclear-transcribed mRNA catabolic
process		 P
IMP
SceS000004685
GO:0006260 DNA replication P
IMP
HsaUPF1
GO:0006281 DNA repair P
IDA
HsaUPF1
GO:0006406 mRNA export from nucleus P
TAS
HsaUPF1
GO:0006415 translational termination P
ISS
SpoSPAC16C9.06c
RCA
SceS000004685
GO:0006417 regulation of translation P
RCA
SceS000004685
GO:0006449 regulation of translational termination P
IMP
HsaUPF1
NAS
HsaUPF1
TAS
SceS000004685
GO:0006605 protein targeting P
RCA
SceS000004685
GO:0006886 intracellular protein transport P
RCA
SceS000004685
GO:0007049 cell cycle P
IMP
HsaUPF1
GO:0008298 intracellular mRNA localization P
IMP
SceS000004685
GO:0009744 response to sucrose stimulus P
IGI
AthLBA1
GO:0010182 sugar mediated signaling pathway P
IMP
AthLBA1
GO:0015031 protein transport P
RCA
SceS000004685
GO:0016246 RNA interference P
IGI
AthLBA1
IMP
CelWBGene00004880
GO:0016567 protein ubiquitination P
IDA
SceS000004685
IMP
SceS000004685
IPI
SceS000004685
GO:0030466 chromatin silencing at silent mating-type
cassette		 P
IGI
SceS000004685
GO:0030538 embryonic genitalia morphogenesis P
IMP
CelWBGene00004880
GO:0034613 cellular protein localization P
RCA
SceS000004685
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00004880
GO:0045184 establishment of protein localization P
RCA
SceS000004685
GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5'
exonucleolytic nonsense-mediated
decay		 P
IGI
SceS000004685
IMP
SceS000004685
GO:0071044 histone mRNA catabolic process P
IMP
HsaUPF1

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2145

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga3204 ENSANGP00000004153
Ashbya gossypii (Ago) ago613 ABR022C
Arabidopsis thaliana (Ath) ath26571 At5g47010.1
Caenorhabditis elegans (Cel) cel19307 Y48G8AL.6
(CE28367;
WBGene00004880)
Candida glabrata (Cgl) cgl848 CAGL0D04312g
Cryptococcus neoformans (Cne) cne5415 179.m00268
Dictyostelium discoideum (Ddi) ddi7226 DDB0188175
Debaryomyces hansenii (Dha) dha3815 DEHA0E13002g
Drosophila melanogaster (Dme) dme17520 CG1559-PA
(FBgn0030354)
Danio rerio (Dre) dre13208 ENSDARP00000013006
Encephalitozoon cuniculi (Ecu) ecu691 19074775
Takifugu rubripes (Fru) fru22990 SINFRUP00000138487
Takifugu rubripes (Fru) fru32431 SINFRUP00000146603
Takifugu rubripes (Fru) fru22991 SINFRUP00000174342
Gallus gallus (Gga) gga14159 ENSGALP00000005090
(UPF1)
Gallus gallus (Gga) gga14160 ENSGALP00000005091
Gallus gallus (Gga) gga14158 ENSGALP00000005092
(UPF1)
Homo sapiens (Hsa) hsa15966 ENSP00000262803
(UPF1)		 Q92900-2
Kluyveromyces lactis (Kla) kla819 KLLA0B06435g
Mus musculus (Mmu) mmu26108 ENSMUSP00000075089
(MGI:107995)		 Q9EPU0-1
Neurospora crassa (Ncr) ncr4118 NCU04242.2
Oryza sativa (Osa) osa58690 6274.m00093
Plasmodium falciparum (Pfa) pfa279 PF10_0057
Rattus norvegicus (Rno) rno12237 ENSRNOP00000027268
(RGD:1305737)
Saccharomyces cerevisiae (Sce) sce4833 YMR080C
(S000004685)
Schizosaccharomyces pombe (Spo) spo1751 SPAC16C9.06c Q09820
Yarrowia lipolytica (Yli) yli3705 YALI0D23881g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
CelWBGene00004880
GO:0005737 cytoplasm C
IDA
CelWBGene00004880
SceS000004685
ISS
SpoSPAC16C9.06c
NAS
DmeFBgn0030354
TAS
CelWBGene00004880
GO:0005829 cytosol C
IDA
SpoSPAC16C9.06c
GO:0005844 polysome C
TAS
SceS000004685
GO:0005886 plasma membrane C
IDA
AthAt5g47010
GO:0003676 nucleic acid binding F
TAS
SceS000004685
GO:0003724 RNA helicase activity F
ISS
AthAt5g47010
GO:0004004 ATP-dependent RNA helicase activity F
ISS
CelWBGene00004880
SpoSPAC16C9.06c
TAS
SceS000004685
GO:0004386 helicase activity F
ISS
DmeFBgn0030354
GO:0005515 protein binding F
IPI
CelWBGene00004880
GO:0005524 ATP binding F
IC
SpoSPAC16C9.06c
GO:0008186 RNA-dependent ATPase activity F
TAS
SceS000004685
GO:0051721 protein phosphatase 2A binding F
IPI
CelWBGene00004880
GO:0000184 nuclear-transcribed mRNA catabolic process,
nonsense-mediated decay		 P
IGI
CelWBGene00004880
IMP
DmeFBgn0030354
ISS
DmeFBgn0030354
SpoSPAC16C9.06c
NAS
DmeFBgn0030354
TAS
SceS000004685
GO:0000956 nuclear-transcribed mRNA catabolic
process		 P
IMP
SceS000004685
GO:0006415 translational termination P
ISS
SpoSPAC16C9.06c
RCA
SceS000004685
GO:0006417 regulation of translation P
RCA
SceS000004685
GO:0006449 regulation of translational termination P
TAS
SceS000004685
GO:0006605 protein targeting P
RCA
SceS000004685
GO:0006886 intracellular protein transport P
RCA
SceS000004685
GO:0008298 intracellular mRNA localization P
IMP
SceS000004685
GO:0009744 response to sucrose stimulus P
IGI
AthAt5g47010
GO:0010182 sugar mediated signaling pathway P
IMP
AthAt5g47010
GO:0015031 protein transport P
RCA
SceS000004685
GO:0016246 RNA interference P
IGI
AthAt5g47010
IMP
CelWBGene00004880
GO:0016567 protein ubiquitination P
IDA
SceS000004685
IMP
SceS000004685
IPI
SceS000004685
GO:0030466 chromatin silencing at silent mating-type
cassette		 P
IGI
SceS000004685
GO:0030538 embryonic genitalia morphogenesis P
IMP
CelWBGene00004880
GO:0034613 cellular protein localization P
RCA
SceS000004685
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00004880
GO:0045184 establishment of protein localization P
RCA
SceS000004685
GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5'
exonucleolytic nonsense-mediated
decay		 P
IGI
SceS000004685
IMP
SceS000004685

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC16C9.06c
(Q09820)		 YMR080C
(S000004685)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000004685
ISS
SpoSPAC16C9.06c
GO:0005829 cytosol C
IDA
SpoSPAC16C9.06c
GO:0005844 polysome C
TAS
SceS000004685
GO:0003676 nucleic acid binding F
TAS
SceS000004685
GO:0004004 ATP-dependent RNA helicase activity F
ISS
SpoSPAC16C9.06c
TAS
SceS000004685
GO:0005524 ATP binding F
IC
SpoSPAC16C9.06c
GO:0008186 RNA-dependent ATPase activity F
TAS
SceS000004685
GO:0000184 nuclear-transcribed mRNA catabolic process,
nonsense-mediated decay		 P
ISS
SpoSPAC16C9.06c
TAS
SceS000004685
GO:0000956 nuclear-transcribed mRNA catabolic
process		 P
IMP
SceS000004685
GO:0006415 translational termination P
ISS
SpoSPAC16C9.06c
RCA
SceS000004685
GO:0006417 regulation of translation P
RCA
SceS000004685
GO:0006449 regulation of translational termination P
TAS
SceS000004685
GO:0006605 protein targeting P
RCA
SceS000004685
GO:0006886 intracellular protein transport P
RCA
SceS000004685
GO:0008298 intracellular mRNA localization P
IMP
SceS000004685
GO:0015031 protein transport P
RCA
SceS000004685
GO:0016567 protein ubiquitination P
IDA
SceS000004685
IMP
SceS000004685
IPI
SceS000004685
GO:0030466 chromatin silencing at silent mating-type
cassette		 P
IGI
SceS000004685
GO:0034613 cellular protein localization P
RCA
SceS000004685
GO:0045184 establishment of protein localization P
RCA
SceS000004685
GO:0070478 nuclear-transcribed mRNA catabolic process, 3'-5'
exonucleolytic nonsense-mediated
decay		 P
IGI
SceS000004685
IMP
SceS000004685

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GO info in one table:

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