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Search term: YMR089C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name YTA12
SGD link S000004695
Alternative ID YMR089C
Description Component, with Afg3p, of the mitochondrial inner membrane m-AAA protease that mediates degradation of misfolded or unassembled proteins and is also required for correct assembly of mitochondrial enzyme complexes
Synonyms YMR089C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0731 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING AAA+-type ATPase containing the peptidase M41 domain

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g06430 GI:18390651
Arabidopsis thaliana (Ath) At1g07510 GI:15222431
Arabidopsis thaliana (Ath) At1g50250 GI:15222913
Arabidopsis thaliana (Ath) At1g79560 GI:15219415
Arabidopsis thaliana (Ath) At2g29080 GI:15227032
Arabidopsis thaliana (Ath) At2g30950 GI:3201633
Arabidopsis thaliana (Ath) At3g02450 GI:15232908
Arabidopsis thaliana (Ath) At3g04340 GI:15229273
Arabidopsis thaliana (Ath) At3g16290 GI:18401080
Arabidopsis thaliana (Ath) At3g47060 GI:18408352
Arabidopsis thaliana (Ath) At4g23940 GI:18416240
Arabidopsis thaliana (Ath) At5g15250 GI:18417611
Arabidopsis thaliana (Ath) At5g42270 GI:18422193
Arabidopsis thaliana (Ath) At5g58870 GI:18424166
Arabidopsis thaliana (Ath) At5g64580 GI:15237737
Caenorhabditis elegans (Cel) CE24356 GI:17510009
Caenorhabditis elegans (Cel) CE27331
(WBGene00022222)		 GI:17570511 Q95XE1
Caenorhabditis elegans (Cel) CE27477
(WBGene00021615)		 GI:17570397 Q965V5
Caenorhabditis elegans (Cel) CE27616 GI:17543190
Drosophila melanogaster (Dme) 7290347 GI:7290347 Q9W4W8
Drosophila melanogaster (Dme) 7294008 GI:7294008
Homo sapiens (Hsa) Hs14776664 GI:14776664
Homo sapiens (Hsa) Hs22047546 GI:22047546
Homo sapiens (Hsa) Hs4507173
(SPG7)		 GI:4507173 O43535
Homo sapiens (Hsa) Hs5802970
(AFG3L2)		 GI:5802970 Q8TA92
Saccharomyces cerevisiae (Sce) YER017c
(S000000819)		 GI:6320854 P39925
Saccharomyces cerevisiae (Sce) YMR089c
(S000004695)		 GI:6323736 P40341
Schizosaccharomyces pombe (Spo) SPBC543.09 GI:19113589 Q9HGM3
Arabidopsis thaliana (Ath) At1g06430 GI:18390651
Arabidopsis thaliana (Ath) At1g07510 GI:15222431
Arabidopsis thaliana (Ath) At1g50250 GI:15222913
Arabidopsis thaliana (Ath) At1g79560 GI:15219415
Arabidopsis thaliana (Ath) At2g29080 GI:15227032
Arabidopsis thaliana (Ath) At2g30950 GI:3201633
Arabidopsis thaliana (Ath) At3g02450 GI:15232908
Arabidopsis thaliana (Ath) At3g04340 GI:15229273
Arabidopsis thaliana (Ath) At3g16290 GI:18401080
Arabidopsis thaliana (Ath) At3g47060 GI:18408352
Arabidopsis thaliana (Ath) At4g23940 GI:18416240
Arabidopsis thaliana (Ath) At5g15250 GI:18417611
Arabidopsis thaliana (Ath) At5g42270 GI:18422193
Arabidopsis thaliana (Ath) At5g58870 GI:18424166
Arabidopsis thaliana (Ath) At5g64580 GI:15237737
Caenorhabditis elegans (Cel) CE24356 GI:17510009
Caenorhabditis elegans (Cel) CE27331
(WBGene00022222)		 GI:17570511 Q95XE1
Caenorhabditis elegans (Cel) CE27477
(WBGene00021615)		 GI:17570397 Q965V5
Caenorhabditis elegans (Cel) CE27616 GI:17543190
Drosophila melanogaster (Dme) 7290347 GI:7290347 Q9W4W8
Drosophila melanogaster (Dme) 7294008 GI:7294008
Homo sapiens (Hsa) Hs14776664 GI:14776664
Homo sapiens (Hsa) Hs22047546 GI:22047546
Homo sapiens (Hsa) Hs4507173
(SPG7)		 GI:4507173 O43535
Homo sapiens (Hsa) Hs5802970
(AFG3L2)		 GI:5802970 Q8TA92
Saccharomyces cerevisiae (Sce) YER017c
(S000000819)		 GI:6320854 P39925
Saccharomyces cerevisiae (Sce) YMR089c
(S000004695)		 GI:6323736 P40341
Schizosaccharomyces pombe (Spo) SPBC543.09 GI:19113589 Q9HGM3


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000004695
GO:0005739 mitochondrion C
IDA
AthAt1g07510
At1g79560
At2g29080
HsaAFG3L2
SceS000004695
S000000819
SpoSPBC543.09
GO:0005743 mitochondrial inner membrane C
IDA
SceS000000819
S000004695
GO:0005745 m-AAA complex C
IDA
SceS000000819
S000004695
ISS
SpoSPBC543.09
GO:0009507 chloroplast C
IDA
AthAt2g30950
At5g42270
At5g64580
At5g58870
At3g47060
At1g06430
At3g04340
At1g79560
At1g50250
At5g15250
At3g16290
At4g23940
GO:0009535 chloroplast thylakoid membrane C
IDA
AthAt2g29080
At1g07510
At1g06430
At1g50250
At2g30950
At5g42270
GO:0009536 plastid C
IDA
AthAt1g07510
At1g79560
GO:0009579 thylakoid C
IDA
AthAt2g30950
At1g06430
At5g42270
GO:0009941 chloroplast envelope C
IDA
AthAt2g30950
At1g06430
At3g04340
At3g16290
At3g47060
At5g64580
At5g42270
GO:0016020 membrane C
IDA
AthAt1g50250
At2g30950
At1g06430
GO:0031977 thylakoid lumen C
IDA
AthAt2g30950
At1g50250
GO:0004176 ATP-dependent peptidase activity F
ISS
AthAt2g29080
At5g58870
At5g15250
At2g30950
At1g79560
At1g06430
At1g50250
At3g47060
At5g42270
GO:0004222 metalloendopeptidase activity F
IDA
HsaSPG7
GO:0005515 protein binding F
IPI
AthAt1g50250
GO:0005524 ATP binding F
ISS
AthAt5g64580
SpoSPBC543.09
GO:0008233 peptidase activity F
IMP
AthAt5g15250
GO:0008237 metallopeptidase activity F
IMP
SceS000000819
S000004695
ISS
AthAt5g58870
At1g79560
At1g06430
At2g30950
At3g47060
At1g50250
At3g16290
At4g23940
At5g15250
At5g42270
SpoSPBC543.09
GO:0008270 zinc ion binding F
ISS
AthAt2g30950
At1g06430
At5g15250
GO:0016887 ATPase activity F
IDA
AthAt5g42270
ISS
AthAt2g30950
At2g29080
At5g58870
At3g47060
At1g79560
At3g04340
At1g50250
At1g07510
At3g02450
At1g06430
At5g15250
At3g16290
At4g23940
At5g42270
SceS000004695
S000000819
SpoSPBC543.09
GO:0051082 unfolded protein binding F
TAS
HsaAFG3L2
SPG7
GO:0006091 generation of precursor metabolites and
energy		 P
NAS
SpoSPBC543.09
GO:0006200 ATP catabolic process P
ISS
SpoSPBC543.09
GO:0006461 protein complex assembly P
IMP
SceS000004695
S000000819
RCA
SceS000004695
GO:0006465 signal peptide processing P
IMP
SceS000000819
S000004695
ISS
SpoSPBC543.09
GO:0006508 proteolysis P
IMP
SceS000004695
S000000819
ISS
SpoSPBC543.09
GO:0006800 oxygen and reactive oxygen species metabolic
process		 P
IDA
AthAt2g30950
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00022222
GO:0007399 nervous system development P
TAS
HsaSPG7
GO:0009790 embryo development P
IMP
AthAt5g64580
GO:0009793 embryo development ending in seed
dormancy		 P
IMP
AthAt1g79560
NAS
AthAt1g79560
At3g04340
At3g16290
GO:0010027 thylakoid membrane organization P
IMP
AthAt2g30950
GO:0010205 photoinhibition P
IMP
AthAt2g30950
At5g42270
GO:0010206 photosystem II repair P
TAS
AthAt1g50250
GO:0010304 PSII associated light-harvesting complex II
catabolic process		 P
IEP
AthAt5g15250
TAS
AthAt1g06430
At2g30950
At1g50250
At5g42270
GO:0016485 protein processing P
RCA
SceS000004695
GO:0030163 protein catabolic process P
IDA
AthAt2g30950
At5g42270
GO:0033108 mitochondrial respiratory chain complex
assembly		 P
ISS
SpoSPBC543.09
GO:0045041 protein import into mitochondrial intermembrane
space		 P
ISS
SpoSPBC543.09
TAS
SceS000000819
S000004695
GO:0051604 protein maturation P
RCA
SceS000004695

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
4947

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) AFG3L2 GI:5802970 Q8TA92
Pan troglodytes (Ptr) AFG3L2 GI:114672121
Canis familiaris (Cfa) AFG3L2 GI:73962221
Mus musculus (Mmu) Afg3l2
(MGI:1916847)		 GI:110625761 Q3U7C0
Rattus norvegicus (Rno) Afg3l2
(RGD:1305259)		 GI:109506690
Gallus gallus (Gga) AFG3L2 GI:50736531
Drosophila melanogaster (Dme) CG6512
(FBgn0036702)		 GI:28574878
Anopheles gambiae (Aga) AgaP_AGAP006949 GI:158286555
Caenorhabditis elegans (Cel) spg-7
(CE34400;
WBGene00004978)		 GI:71994521
Schizosaccharomyces pombe (Spo) SPBC543.09 GI:19113589 Q9HGM3
Saccharomyces cerevisiae (Sce) YTA12
(S000004695)		 GI:6323736 P40341
Kluyveromyces lactis (Kla) KLLA0F13706g GI:50311345
Eremothecium gossypii (Ego) AGOS_ABL041W GI:45185189
Magnaporthe grisea (Mgr) MGG_07441 GI:39972279
Neurospora crassa (Ncr) NCU01479.1 GI:32414877
Arabidopsis thaliana (Ath) ftsh3 GI:30684118
Arabidopsis thaliana (Ath) ftsh10 GI:22329400
Oryza sativa (Osa) Os05g0458400 GI:115464291
Oryza sativa (Osa) Os01g0842600 GI:115440989
Plasmodium falciparum (Pfa) PF11_0203 GI:124804008