YOGY Home YOGY Help

Search term: YMR106C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name YKU80
SGD link S000004712
Alternative ID YMR106C
Description Subunit of the telomeric Ku complex (Yku70p-Yku80p), involved in telomere length maintenance, structure and telomere position effect; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair
Synonyms YMR106C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2326 AC-HYP-

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING DNA-binding subunit of a DNA-dependent protein kinase (Ku80 autoantigen)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g48050 GI:15221063
Caenorhabditis elegans (Cel) CE00660
(WBGene00000520)		 GI:17552754 Q21829
Homo sapiens (Hsa) Hs10863945
(XRCC5)		 GI:10863945 P13010
Saccharomyces cerevisiae (Sce) YMR106c
(S000004712)		 GI:6323753 Q04437
Schizosaccharomyces pombe (Spo) SPBC543.03c GI:19113583 Q9HGM8


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000781 chromosome, telomeric region C
IDA
SpoSPBC543.03c
GO:0000783 nuclear telomere cap complex C
TAS
HsaXRCC5
GO:0000784 nuclear chromosome, telomeric region C
IDA
HsaXRCC5
GO:0000790 nuclear chromatin C
TAS
SceS000004712
GO:0005634 nucleus C
IDA
SpoSPBC543.03c
GO:0005654 nucleoplasm C
EXP
HsaXRCC5
GO:0005724 nuclear telomeric heterochromatin C
TAS
SceS000004712
GO:0005829 cytosol C
IDA
SpoSPBC543.03c
GO:0043564 Ku70:Ku80 complex C
IDA
HsaXRCC5
SceS000004712
GO:0070419 nonhomologous end joining complex C
IDA
HsaXRCC5
GO:0003677 DNA binding F
IDA
SceS000004712
NAS
HsaXRCC5
GO:0003684 damaged DNA binding F
TAS
SceS000004712
GO:0003690 double-stranded DNA binding F
IDA
AthAt1g48050
TAS
HsaXRCC5
GO:0003691 double-stranded telomeric DNA binding F
IDA
HsaXRCC5
GO:0003723 RNA binding F
IDA
SceS000004712
GO:0004003 ATP-dependent DNA helicase activity F
ISS
SpoSPBC543.03c
GO:0005515 protein binding F
IPI
AthAt1g48050
HsaXRCC5
GO:0008022 protein C-terminus binding F
IPI
HsaXRCC5
GO:0010843 promoter binding F
IDA
HsaXRCC5
GO:0042162 telomeric DNA binding F
IDA
HsaXRCC5
SceS000004712
SpoSPBC543.03c
GO:0046982 protein heterodimerization activity F
ISS
SpoSPBC543.03c
GO:0051575 5'-deoxyribose-5-phosphate lyase
activity		 F
IMP
HsaXRCC5
GO:0000084 S phase of mitotic cell cycle P
IMP
SpoSPBC543.03c
GO:0000723 telomere maintenance P
IMP
SceS000004712
SpoSPBC543.03c
TAS
AthAt1g48050
HsaXRCC5
GO:0000724 double-strand break repair via homologous
recombination		 P
IMP
SceS000004712
GO:0006281 DNA repair P
TAS
AthAt1g48050
GO:0006302 double-strand break repair P
IMP
AthAt1g48050
TAS
HsaXRCC5
GO:0006303 double-strand break repair via nonhomologous end
joining		 P
IDA
SceS000004712
IMP
HsaXRCC5
SpoSPBC543.03c
TAS
AthAt1g48050
HsaXRCC5
GO:0006310 DNA recombination P
TAS
HsaXRCC5
GO:0006333 chromatin assembly or disassembly P
IDA
SceS000004712
GO:0006342 chromatin silencing P
IDA
SceS000004712
IMP
SceS000004712
GO:0006950 response to stress P
IMP
CelWBGene00000520
GO:0007535 donor selection P
IDA
SceS000004712
IGI
SceS000004712
IMP
SceS000004712
GO:0009408 response to heat P
IEP
AthAt1g48050
GO:0015074 DNA integration P
TAS
AthAt1g48050
GO:0019047 provirus integration P
EXP
HsaXRCC5
GO:0019059 initiation of viral infection P
EXP
HsaXRCC5
GO:0034502 protein localization to chromosome P
IGI
SceS000004712
GO:0040007 growth P
IMP
CelWBGene00000520

Back to the top

HomoloGene results:

HomoloGene cluster Phylogenetic pattern
40681

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) XRCC5 GI:10863945 P13010
Pan troglodytes (Ptr) XRCC5 GI:114583168
Canis familiaris (Cfa) XRCC5 GI:74005704
Mus musculus (Mmu) Xrcc5
(MGI:104517)		 GI:27753977 P27641
Rattus norvegicus (Rno) Xrcc5
(RGD:3976)		 GI:41056215 36381
Gallus gallus (Gga) XRCC5 GI:118093791
Anopheles gambiae (Aga) AgaP_AGAP009910 GI:158298889
Schizosaccharomyces pombe (Spo) pku80
(SPBC543.03c)		 GI:19113583 Q9HGM8
Saccharomyces cerevisiae (Sce) YKU80
(S000004712)		 GI:6323753 Q04437
Eremothecium gossypii (Ego) AGOS_ABL030W GI:54299354
Magnaporthe grisea (Mgr) MGG_10157 GI:145614348
Neurospora crassa (Ncr) NCU00077.1 GI:32403100
Arabidopsis thaliana (Ath) KU80 GI:18402015
Oryza sativa (Osa) Os03g0856200 GI:115456693


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000781 chromosome, telomeric region C
IDA
SpoSPBC543.03c
GO:0000783 nuclear telomere cap complex C
TAS
HsaXRCC5
GO:0000784 nuclear chromosome, telomeric region C
IDA
HsaXRCC5
GO:0000790 nuclear chromatin C
TAS
SceS000004712
GO:0005634 nucleus C
IDA
MmuMGI:104517
SpoSPBC543.03c
ISO
MmuMGI:104517
GO:0005654 nucleoplasm C
EXP
HsaXRCC5
GO:0005724 nuclear telomeric heterochromatin C
TAS
SceS000004712
GO:0005737 cytoplasm C
IDA
MmuMGI:104517
ISO
MmuMGI:104517
GO:0005829 cytosol C
IDA
SpoSPBC543.03c
GO:0043234 protein complex C
ISO
MmuMGI:104517
GO:0043564 Ku70:Ku80 complex C
IDA
HsaXRCC5
SceS000004712
GO:0070419 nonhomologous end joining complex C
IDA
HsaXRCC5
GO:0003677 DNA binding F
IDA
SceS000004712
NAS
HsaXRCC5
GO:0003684 damaged DNA binding F
TAS
SceS000004712
GO:0003690 double-stranded DNA binding F
IDA
AthKU80
ISO
MmuMGI:104517
TAS
HsaXRCC5
GO:0003691 double-stranded telomeric DNA binding F
IDA
HsaXRCC5
GO:0003723 RNA binding F
IDA
SceS000004712
GO:0004003 ATP-dependent DNA helicase activity F
ISS
SpoSPBC543.03c
GO:0005515 protein binding F
IPI
AthKU80
HsaXRCC5
GO:0008022 protein C-terminus binding F
IPI
HsaXRCC5
GO:0010843 promoter binding F
IDA
HsaXRCC5
GO:0042162 telomeric DNA binding F
IDA
HsaXRCC5
SceS000004712
SpoSPBC543.03c
GO:0046982 protein heterodimerization activity F
ISS
SpoSPBC543.03c
GO:0051575 5'-deoxyribose-5-phosphate lyase
activity		 F
IMP
HsaXRCC5
GO:0000084 S phase of mitotic cell cycle P
IMP
SpoSPBC543.03c
GO:0000723 telomere maintenance P
IMP
SceS000004712
SpoSPBC543.03c
TAS
AthKU80
HsaXRCC5
GO:0000724 double-strand break repair via homologous
recombination		 P
IMP
SceS000004712
GO:0006281 DNA repair P
TAS
AthKU80
GO:0006302 double-strand break repair P
IGI
MmuMGI:104517
IMP
AthKU80
MmuMGI:104517
TAS
HsaXRCC5
GO:0006303 double-strand break repair via nonhomologous end
joining		 P
IDA
SceS000004712
IMP
HsaXRCC5
SpoSPBC543.03c
TAS
AthKU80
HsaXRCC5
GO:0006310 DNA recombination P
TAS
HsaXRCC5
GO:0006333 chromatin assembly or disassembly P
IDA
SceS000004712
GO:0006342 chromatin silencing P
IDA
SceS000004712
IMP
SceS000004712
GO:0007535 donor selection P
IDA
SceS000004712
IGI
SceS000004712
IMP
SceS000004712
GO:0008283 cell proliferation P
IMP
MmuMGI:104517
GO:0009408 response to heat P
IEP
AthKU80
GO:0015074 DNA integration P
TAS
AthKU80
GO:0019047 provirus integration P
EXP
HsaXRCC5
GO:0019059 initiation of viral infection P
EXP
HsaXRCC5
GO:0034502 protein localization to chromosome P
IGI
SceS000004712
GO:0043066 negative regulation of apoptosis P
IMP
MmuMGI:104517
GO:0050769 positive regulation of neurogenesis P
IMP
MmuMGI:104517
GO:0060218 hemopoietic stem cell differentiation P
IMP
MmuMGI:104517
GO:0071475 cellular hyperosmotic salinity
response		 P
ISO
MmuMGI:104517
GO:0071481 cellular response to X-ray P
ISO
MmuMGI:104517

Back to the top

OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_4434

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga12196 ENSANGP00000013304
Ashbya gossypii (Ago) ago562 ABL030W
Arabidopsis thaliana (Ath) ath4065 At1g48050.1
Candida glabrata (Cgl) cgl3669 CAGL0K03443g
Cryptococcus neoformans (Cne) cne4703 186.m03559
Dictyostelium discoideum (Ddi) ddi7841 DDB0186918
Debaryomyces hansenii (Dha) dha750 DEHA0B01584g
Drosophila melanogaster (Dme) dme2548 CG18801-PA
(FBgn0041627)
Danio rerio (Dre) dre25034 ENSDARP00000012509
(xrcc5)		 Q5FY48
Takifugu rubripes (Fru) fru16709 SINFRUP00000145346
Gallus gallus (Gga) gga21783 ENSGALP00000018706
(XRCC5)
Homo sapiens (Hsa) hsa19249 ENSP00000329528
(XRCC5)		 P13010
Kluyveromyces lactis (Kla) kla1093 KLLA0B12672g
Mus musculus (Mmu) mmu519 ENSMUSP00000027379
(MGI:104517)		 P27641
Neurospora crassa (Ncr) ncr75 NCU00077.2
Oryza sativa (Osa) osa67446 6856.m00194
Oryza sativa (Osa) osa85415 8376.m00092
Rattus norvegicus (Rno) rno30214 ENSRNOP00000021656
(RGD:3976)		 Q6P7P8
Saccharomyces cerevisiae (Sce) sce4861 YMR106C
(S000004712)
Schizosaccharomyces pombe (Spo) spo4301 SPBC543.03c Q9HGM8
Yarrowia lipolytica (Yli) yli3945 YALI0E02068g