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Search term: YMR110C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name HFD1
SGD link S000004716
Alternative ID YMR110C
Description Putative fatty aldehyde dehydrogenase, located in the mitochondrial outer membrane and also in lipid particles; has similarity to human fatty aldehyde dehydrogenase (FALDH) which is implicated in Sjogren-Larsson syndrome
Synonyms YMR110C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2456 ACDHY--

KOGs classification KOGs description
METABOLISM Aldehyde dehydrogenase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g44170 GI:15219358
Arabidopsis thaliana (Ath) At4g34240 GI:7484798
Arabidopsis thaliana (Ath) At4g36250 GI:15234364
Caenorhabditis elegans (Cel) CE13415
(WBGene00000111)		 GI:17564084 O44555
Caenorhabditis elegans (Cel) CE27441
(WBGene00000110)		 GI:17563946
Drosophila melanogaster (Dme) 7304212 GI:7304212
Homo sapiens (Hsa) Hs18580975 GI:18580975
Homo sapiens (Hsa) Hs18603595 GI:18603595
Homo sapiens (Hsa) Hs20481620 GI:20481620
Homo sapiens (Hsa) Hs21359829 GI:13325114 P30838
Homo sapiens (Hsa) Hs4502043
(ALDH3B1)		 GI:4502043 P43353
Homo sapiens (Hsa) Hs4502045 GI:4502045
Homo sapiens (Hsa) Hs4557303
(ALDH3A2)		 GI:4557303 P51648
Homo sapiens (Hsa) HsM4502035 GI:4502035
Saccharomyces cerevisiae (Sce) YMR110c
(S000004716)		 GI:6323757 Q04458


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000004716
GO:0005741 mitochondrial outer membrane C
IDA
SceS000004716
GO:0005768 endosome C
IDA
SceS000004716
GO:0005773 vacuole C
IDA
AthAt1g44170
GO:0005783 endoplasmic reticulum C
IDA
AthAt1g44170
At4g36250
GO:0005811 lipid particle C
IDA
SceS000004716
GO:0009507 chloroplast C
IDA
AthAt4g34240
GO:0009536 plastid C
ISS
AthAt4g34240
At1g44170
GO:0016020 membrane C
IDA
AthAt4g36250
At1g44170
GO:0031307 integral to mitochondrial outer
membrane		 C
IDA
SceS000004716
GO:0004028 3-chloroallyl aldehyde dehydrogenase
activity		 F
ISS
AthAt4g36250
At1g44170
At4g34240
SceS000004716
TAS
HsaALDH3A2
ALDH3B1
GO:0004029 aldehyde dehydrogenase (NAD) activity F
ISS
AthAt4g34240
At1g44170
At4g36250
GO:0006066 alcohol metabolic process P
TAS
HsaALDH3B1
GO:0006081 cellular aldehyde metabolic process P
IC
SceS000004716
GO:0006629 lipid metabolic process P
TAS
HsaALDH3A2
ALDH3B1
GO:0006914 autophagy P
RCA
SceS000004716
GO:0007417 central nervous system development P
TAS
HsaALDH3A2
GO:0007422 peripheral nervous system development P
TAS
HsaALDH3A2
GO:0008544 epidermis development P
TAS
HsaALDH3A2
GO:0009269 response to desiccation P
IEP
AthAt1g44170
GO:0009414 response to water deprivation P
IEP
AthAt4g34240
GO:0009651 response to salt stress P
IEP
AthAt1g44170
GO:0009737 response to abscisic acid stimulus P
IEP
AthAt4g34240
At1g44170
GO:0045184 establishment of protein localization P
RCA
SceS000004716

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
73890

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) ALDH3B1 GI:4502043 P43353
Canis familiaris (Cfa) ALDH3B1 GI:73982763
Mus musculus (Mmu) Aldh3b1
(MGI:1914939)		 GI:34328288 Q3TX25
Rattus norvegicus (Rno) Aldh3b1
(RGD:1359546)		 GI:55742838
Gallus gallus (Gga) ALDH3B1 GI:118090948
Drosophila melanogaster (Dme) Aldh-III
(FBgn0010548)		 GI:45552499
Anopheles gambiae (Aga) AgaP_AGAP005124 GI:158292610
Saccharomyces cerevisiae (Sce) HFD1
(S000004716)		 GI:6323757 Q04458
Kluyveromyces lactis (Kla) KLLA0B12540g GI:50304279
Magnaporthe grisea (Mgr) MGG_07270 GI:145612641
Neurospora crassa (Ncr) NCU04013.1 GI:32405438


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:1914939
GO:0005739 mitochondrion C
IDA
SceS000004716
GO:0005741 mitochondrial outer membrane C
IDA
SceS000004716
GO:0005768 endosome C
IDA
SceS000004716
GO:0005811 lipid particle C
IDA
DmeFBgn0010548
SceS000004716
GO:0031307 integral to mitochondrial outer
membrane		 C
IDA
SceS000004716
GO:0003674 molecular_function F
ND
MmuMGI:1914939
GO:0004028 3-chloroallyl aldehyde dehydrogenase
activity		 F
ISS
SceS000004716
TAS
HsaALDH3B1
GO:0016620 oxidoreductase activity, acting on the aldehyde or
oxo group of donors, NAD or NADP as
acceptor		 F
ISS
DmeFBgn0010548
GO:0006066 alcohol metabolic process P
TAS
HsaALDH3B1
GO:0006081 cellular aldehyde metabolic process P
IC
SceS000004716
GO:0006629 lipid metabolic process P
TAS
HsaALDH3B1
GO:0006914 autophagy P
RCA
SceS000004716
GO:0008150 biological_process P
ND
MmuMGI:1914939
GO:0045184 establishment of protein localization P
RCA
SceS000004716

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_224

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga500 ENSANGP00000009992
Anopheles gambiae (Aga) aga501 ENSANGP00000025470
Anopheles gambiae (Aga) aga502 ENSANGP00000025842
Arabidopsis thaliana (Ath) ath3888 At1g44170.1
Arabidopsis thaliana (Ath) ath3889 At1g44170.2
Arabidopsis thaliana (Ath) ath21558 At4g34240.1
Arabidopsis thaliana (Ath) ath21559 At4g34240.2
Caenorhabditis elegans (Cel) cel14705 T05H4.13a
(CE27441;
WBGene00000110)
Caenorhabditis elegans (Cel) cel14706 T05H4.13b
(CE30827)
Caenorhabditis elegans (Cel) cel14707 T05H4.13c
(CE33307)
Candida glabrata (Cgl) cgl3672 CAGL0K03509g
Cryptococcus neoformans (Cne) cne1705 164.m02043
Cryptococcus neoformans (Cne) cne1789 164.m02214
Dictyostelium discoideum (Ddi) ddi13625 DDB0185188
Debaryomyces hansenii (Dha) dha6151 DEHA0G10175g
Drosophila melanogaster (Dme) dme3656 CG11140-PA
(FBgn0010548)
Drosophila melanogaster (Dme) dme3654 CG11140-PB
(FBgn0010548)
Drosophila melanogaster (Dme) dme3653 CG11140-PC
(FBgn0010548)
Drosophila melanogaster (Dme) dme3657 CG11140-PD
(FBgn0010548)
Drosophila melanogaster (Dme) dme3650 CG11140-PE
(FBgn0010548)
Drosophila melanogaster (Dme) dme3651 CG11140-PF
(FBgn0010548)
Drosophila melanogaster (Dme) dme3652 CG11140-PG
(FBgn0010548)
Drosophila melanogaster (Dme) dme3649 CG11140-PH
(FBgn0010548)
Drosophila melanogaster (Dme) dme3655 CG11140-PI
(FBgn0010548)
Danio rerio (Dre) dre17584 ENSDARP00000002746
(aldh3d1)		 Q7ZU10
Danio rerio (Dre) dre8313 ENSDARP00000004886
Danio rerio (Dre) dre8312 ENSDARP00000044934
Takifugu rubripes (Fru) fru24640 SINFRUP00000129119
Takifugu rubripes (Fru) fru10726 SINFRUP00000134534
Takifugu rubripes (Fru) fru10731 SINFRUP00000134540
Takifugu rubripes (Fru) fru541 SINFRUP00000148431
Takifugu rubripes (Fru) fru542 SINFRUP00000166787
Takifugu rubripes (Fru) fru24641 SINFRUP00000170092
Takifugu rubripes (Fru) fru10727 SINFRUP00000174687
Gallus gallus (Gga) gga18555 ENSGALP00000005508
Gallus gallus (Gga) gga18558 ENSGALP00000005509
(ALDH3B1)
Gallus gallus (Gga) gga18562 ENSGALP00000005512
Gallus gallus (Gga) gga18557 ENSGALP00000005513
Gallus gallus (Gga) gga18559 ENSGALP00000005514
Gallus gallus (Gga) gga18561 ENSGALP00000005515
Gallus gallus (Gga) gga8972 ENSGALP00000007586
(ALDH3A2)		 Q5ZLE2
Homo sapiens (Hsa) hsa6100 ENSP00000007633
(ALDH3B1)		 P43353-1
Homo sapiens (Hsa) hsa13245 ENSP00000176643
(ALDH3A2)		 P51648-1
Homo sapiens (Hsa) hsa13251 ENSP00000225740
(ALDH3A1)		 P30838
Homo sapiens (Hsa) hsa6101 ENSP00000341582
(ALDH3B1)		 P43353-2
Homo sapiens (Hsa) hsa13246 ENSP00000345774
(ALDH3A2)		 P51648-2
Kluyveromyces lactis (Kla) kla1087 KLLA0B12540g
Mus musculus (Mmu) mmu3861 ENSMUSP00000019246
(MGI:1353451)		 B7ZN13
Mus musculus (Mmu) mmu13036 ENSMUSP00000056276
(MGI:1914939)		 Q80VQ0
Mus musculus (Mmu) mmu3862 ENSMUSP00000067767
(MGI:1353452)		 B1ATI0
Mus musculus (Mmu) mmu13040 ENSMUSP00000071343
Mus musculus (Mmu) mmu13038 ENSMUSP00000071877
Mus musculus (Mmu) mmu13041 ENSMUSP00000072494
Mus musculus (Mmu) mmu3863 ENSMUSP00000073764
(MGI:1353452)		 Q99L64
Mus musculus (Mmu) mmu13047 ENSMUSP00000075745
Mus musculus (Mmu) mmu13046 ENSMUSP00000076573
Mus musculus (Mmu) mmu13039 ENSMUSP00000078354
Mus musculus (Mmu) mmu13044 ENSMUSP00000078541
Neurospora crassa (Ncr) ncr3891 NCU04013.2
Oryza sativa (Osa) osa1665 1890.m00137
Oryza sativa (Osa) osa41482 5259.m00138
Oryza sativa (Osa) osa42042 5272.m00153
Oryza sativa (Osa) osa69373 7075.m00139
Rattus norvegicus (Rno) rno5198 ENSRNOP00000003182
(RGD:2088)		 P11883
Rattus norvegicus (Rno) rno5200 ENSRNOP00000003200
(RGD:61866)
Rattus norvegicus (Rno) rno3411 ENSRNOP00000023789
(RGD:1359546)		 Q5XI42
Rattus norvegicus (Rno) rno3414 ENSRNOP00000024034
(GI:688778)
Rattus norvegicus (Rno) rno5199 ENSRNOP00000045886
(RGD:61866)
Saccharomyces cerevisiae (Sce) sce4865 YMR110C
(S000004716)
Yarrowia lipolytica (Yli) yli589 YALI0A17875g
Yarrowia lipolytica (Yli) yli799 YALI0B01298g
Yarrowia lipolytica (Yli) yli4497 YALI0E15400g
Yarrowia lipolytica (Yli) yli6342 YALI0F23793g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:1914939
GO:0005634 nucleus C
ISO
MmuMGI:1353452
GO:0005737 cytoplasm C
ISO
MmuMGI:1353451
NAS
MmuMGI:1353451
GO:0005739 mitochondrion C
IDA
MmuMGI:1353452
SceS000004716
GO:0005741 mitochondrial outer membrane C
IDA
SceS000004716
GO:0005743 mitochondrial inner membrane C
IDA
MmuMGI:1353452
GO:0005768 endosome C
IDA
SceS000004716
GO:0005773 vacuole C
IDA
AthAt1g44170
GO:0005783 endoplasmic reticulum C
IDA
AthAt1g44170
ISO
MmuMGI:1353452
GO:0005811 lipid particle C
IDA
DmeFBgn0010548
SceS000004716
GO:0005829 cytosol C
ISO
MmuMGI:1353451
MGI:1353452
GO:0009507 chloroplast C
IDA
AthAt4g34240
GO:0009536 plastid C
ISS
AthAt4g34240
At1g44170
GO:0016020 membrane C
IDA
AthAt1g44170
GO:0031307 integral to mitochondrial outer
membrane		 C
IDA
SceS000004716
GO:0042406 extrinsic to endoplasmic reticulum
membrane		 C
ISO
MmuMGI:1353452
GO:0003674 molecular_function F
ND
MmuMGI:1914939
GO:0004028 3-chloroallyl aldehyde dehydrogenase
activity		 F
IDA
MmuMGI:1353451
IMP
MmuMGI:1353451
ISO
MmuMGI:1353452
MGI:1353451
ISS
AthAt1g44170
At4g34240
SceS000004716
GO:0004029 aldehyde dehydrogenase (NAD) activity F
ISS
AthAt4g34240
At1g44170
GO:0016620 oxidoreductase activity, acting on the aldehyde or
oxo group of donors, NAD or NADP as
acceptor		 F
IDA
MmuMGI:1353451
ISS
DmeFBgn0010548
GO:0000302 response to reactive oxygen species P
ISO
MmuMGI:1353452
GO:0001666 response to hypoxia P
ISO
MmuMGI:1353451
GO:0006081 cellular aldehyde metabolic process P
IC
SceS000004716
GO:0006914 autophagy P
RCA
SceS000004716
GO:0008150 biological_process P
ND
MmuMGI:1914939
GO:0008152 metabolic process P
IDA
MmuMGI:1353451
IMP
MmuMGI:1353451
GO:0008284 positive regulation of cell proliferation P
ISO
MmuMGI:1353451
GO:0009269 response to desiccation P
IEP
AthAt1g44170
GO:0009414 response to water deprivation P
IEP
AthAt4g34240
GO:0009651 response to salt stress P
IEP
AthAt1g44170
GO:0009737 response to abscisic acid stimulus P
IEP
AthAt4g34240
At1g44170
GO:0014070 response to organic cyclic substance P
ISO
MmuMGI:1353451
GO:0042493 response to drug P
ISO
MmuMGI:1353451
GO:0045184 establishment of protein localization P
RCA
SceS000004716
GO:0046292 formaldehyde metabolic process P
ISO
MmuMGI:1353452
GO:0051384 response to glucocorticoid stimulus P
ISO
MmuMGI:1353451
GO:0051591 response to cAMP P
ISO
MmuMGI:1353451

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s.khadayate@ucl.ac.uk