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Search term: YMR189W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name GCV2
SGD link S000004801
Alternative ID YMR189W
Description P subunit of the mitochondrial glycine decarboxylase complex, required for the catabolism of glycine to 5,10-methylene-THF; expression is regulated by levels of 5,10-methylene-THF in the cytoplasm
Synonyms YMR189W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2040 ACDHYP-

KOGs classification KOGs description
METABOLISM Glycine dehydrogenase (decarboxylating)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g26080 GI:15225249
Arabidopsis thaliana (Ath) At4g33010 GI:15234036
Caenorhabditis elegans (Cel) CE02846
(WBGene00020022)		 GI:17535605 Q21962
Drosophila melanogaster (Dme) 7299318 GI:7299318
Homo sapiens (Hsa) Hs18573217 GI:18573217
Homo sapiens (Hsa) Hs20471026 GI:20471026
Homo sapiens (Hsa) Hs4504013 GI:4504013
Saccharomyces cerevisiae (Sce) YMR189w
(S000004801)		 GI:6323843 P49095
Schizosaccharomyces pombe (Spo) SPAC13G6.06c GI:19113744 Q09785


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
AthAt4g33010
At2g26080
SceS000004801
SpoSPAC13G6.06c
ISS
SpoSPAC13G6.06c
GO:0005960 glycine cleavage complex C
ISS
AthAt4g33010
At2g26080
SceS000004801
SpoSPAC13G6.06c
GO:0009507 chloroplast C
IDA
AthAt4g33010
At2g26080
GO:0009941 chloroplast envelope C
IDA
AthAt4g33010
At2g26080
GO:0048046 apoplast C
IDA
AthAt4g33010
GO:0004375 glycine dehydrogenase (decarboxylating)
activity		 F
IDA
SceS000004801
ISS
AthAt4g33010
At2g26080
SpoSPAC13G6.06c
GO:0005515 protein binding F
IPI
AthAt4g33010
GO:0005524 ATP binding F
IDA
AthAt2g26080
GO:0006546 glycine catabolic process P
IMP
AthAt4g33010
GO:0006730 one-carbon metabolic process P
IGI
SceS000004801
GO:0019464 glycine decarboxylation via glycine cleavage
system		 P
IEP
SceS000004801
IMP
SceS000004801
ISS
AthAt4g33010
At2g26080
SpoSPAC13G6.06c
GO:0046686 response to cadmium ion P
IEP
AthAt4g33010

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
141

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) GLDC GI:108773801
Pan troglodytes (Ptr) GLDC GI:114623733
Canis familiaris (Cfa) GLDC GI:73970982
Mus musculus (Mmu) Gldc
(MGI:1341155)		 GI:20070408 Q8BJQ7
Rattus norvegicus (Rno) Gldc GI:62642167
Gallus gallus (Gga) GLDC GI:45383510
Drosophila melanogaster (Dme) CG3999
(FBgn0037801)		 GI:24645648
Anopheles gambiae (Aga) AgaP_AGAP003321 GI:118791093
Caenorhabditis elegans (Cel) R12C12.1
(CE02846;
WBGene00020022)		 GI:17535605 Q21962
Schizosaccharomyces pombe (Spo) SPAC13G6.06c GI:19113744 Q09785
Saccharomyces cerevisiae (Sce) GCV2
(S000004801)		 GI:6323843 P49095
Kluyveromyces lactis (Kla) KLLA0D12738g GI:50307303
Magnaporthe grisea (Mgr) MGG_12518 GI:145609650
Neurospora crassa (Ncr) NCU02475.1 GI:32422461
Arabidopsis thaliana (Ath) AtGLDP2 GI:15225249
Arabidopsis thaliana (Ath) AtGLDP1 GI:15234036
Oryza sativa (Osa) Os01g0711400 GI:115439533


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
AthAtGLDP2
AtGLDP1
MmuMGI:1341155
SceS000004801
SpoSPAC13G6.06c
ISO
MmuMGI:1341155
ISS
SpoSPAC13G6.06c
GO:0005960 glycine cleavage complex C
ISO
MmuMGI:1341155
ISS
AthAtGLDP2
AtGLDP1
DmeFBgn0037801
SceS000004801
SpoSPAC13G6.06c
GO:0009507 chloroplast C
IDA
AthAtGLDP2
AtGLDP1
GO:0009941 chloroplast envelope C
IDA
AthAtGLDP2
AtGLDP1
GO:0048046 apoplast C
IDA
AthAtGLDP1
GO:0004375 glycine dehydrogenase (decarboxylating)
activity		 F
IDA
SceS000004801
ISO
MmuMGI:1341155
ISS
AthAtGLDP2
AtGLDP1
DmeFBgn0037801
SpoSPAC13G6.06c
GO:0005515 protein binding F
IPI
AthAtGLDP1
GO:0005524 ATP binding F
IDA
AthAtGLDP2
GO:0009055 electron carrier activity F
TAS
HsaGLDC
GO:0016594 glycine binding F
ISO
MmuMGI:1341155
GO:0030170 pyridoxal phosphate binding F
ISO
MmuMGI:1341155
GO:0042803 protein homodimerization activity F
ISO
MmuMGI:1341155
GO:0046983 protein dimerization activity F
ISO
MmuMGI:1341155
GO:0006546 glycine catabolic process P
IMP
AthAtGLDP1
TAS
HsaGLDC
GO:0006730 one-carbon metabolic process P
IGI
SceS000004801
GO:0019464 glycine decarboxylation via glycine cleavage
system		 P
IEP
SceS000004801
IMP
SceS000004801
ISO
MmuMGI:1341155
ISS
AthAtGLDP2
AtGLDP1
SpoSPAC13G6.06c
GO:0046686 response to cadmium ion P
IEP
AthAtGLDP1

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1135

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga5694 ENSANGP00000014378
Arabidopsis thaliana (Ath) ath9533 At2g26080.1
Arabidopsis thaliana (Ath) ath21412 At4g33010.1
Caenorhabditis elegans (Cel) cel13911 R12C12.1a
(CE02846;
WBGene00020022)
Caenorhabditis elegans (Cel) cel13912 R12C12.1b
(CE33434)
Candida glabrata (Cgl) cgl4096 CAGL0L00429g
Cryptococcus neoformans (Cne) cne5253 179.m00102
Dictyostelium discoideum (Ddi) ddi12939 DDB0231130
Debaryomyces hansenii (Dha) dha4575 DEHA0F04202g
Drosophila melanogaster (Dme) dme11872 CG3999-PA
(FBgn0037801)
Danio rerio (Dre) dre23959 ENSDARP00000027808
Danio rerio (Dre) dre26117 ENSDARP00000044662
Escherichia coli (Eco) eco2805 16130805
Takifugu rubripes (Fru) fru3199 SINFRUP00000156491
Takifugu rubripes (Fru) fru3200 SINFRUP00000168633
Takifugu rubripes (Fru) fru3198 SINFRUP00000169826
Takifugu rubripes (Fru) fru3201 SINFRUP00000170378
Takifugu rubripes (Fru) fru3202 SINFRUP00000173767
Gallus gallus (Gga) gga27740 ENSGALP00000024228
(GLDC)		 P15505
Kluyveromyces lactis (Kla) kla2629 KLLA0D12738g
Mus musculus (Mmu) mmu13590 ENSMUSP00000025778
(MGI:1341155)		 Q91W43
Mus musculus (Mmu) mmu13591 ENSMUSP00000065263
(MGI:1341155)		 Q8BJQ7
Neurospora crassa (Ncr) ncr2399 NCU02475.2
Oryza sativa (Osa) osa2501 1951.m00148
Oryza sativa (Osa) osa11081 2763.m00155
Oryza sativa (Osa) osa22742 3715.m00141
Oryza sativa (Osa) osa30826 4367.m00139
Rattus norvegicus (Rno) rno3971 ENSRNOP00000015456
(RGD:1308660)
Rattus norvegicus (Rno) rno3972 ENSRNOP00000043788
(RGD:1308660)
Saccharomyces cerevisiae (Sce) sce4955 YMR189W
(S000004801)
Schizosaccharomyces pombe (Spo) spo2730 SPAC13G6.06c Q09785
Yarrowia lipolytica (Yli) yli327 YALI0A09856g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
AthAt4g33010
At2g26080
MmuMGI:1341155
SceS000004801
SpoSPAC13G6.06c
ISO
MmuMGI:1341155
ISS
SpoSPAC13G6.06c
GO:0005960 glycine cleavage complex C
ISO
MmuMGI:1341155
ISS
AthAt4g33010
At2g26080
DmeFBgn0037801
SceS000004801
SpoSPAC13G6.06c
GO:0009507 chloroplast C
IDA
AthAt4g33010
At2g26080
GO:0009941 chloroplast envelope C
IDA
AthAt4g33010
At2g26080
GO:0048046 apoplast C
IDA
AthAt4g33010
GO:0004375 glycine dehydrogenase (decarboxylating)
activity		 F
IDA
SceS000004801
ISO
MmuMGI:1341155
ISS
AthAt4g33010
At2g26080
DmeFBgn0037801
SpoSPAC13G6.06c
GO:0005515 protein binding F
IPI
AthAt4g33010
GO:0005524 ATP binding F
IDA
AthAt2g26080
GO:0016594 glycine binding F
ISO
MmuMGI:1341155
GO:0030170 pyridoxal phosphate binding F
ISO
MmuMGI:1341155
GO:0042803 protein homodimerization activity F
ISO
MmuMGI:1341155
GO:0046983 protein dimerization activity F
ISO
MmuMGI:1341155
GO:0006546 glycine catabolic process P
IMP
AthAt4g33010
GO:0006730 one-carbon metabolic process P
IGI
SceS000004801
GO:0019464 glycine decarboxylation via glycine cleavage
system		 P
IEP
SceS000004801
IMP
SceS000004801
ISO
MmuMGI:1341155
ISS
AthAt4g33010
At2g26080
SpoSPAC13G6.06c
GO:0046686 response to cadmium ion P
IEP
AthAt4g33010

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC13G6.06c
(Q09785)		 YMR189W
(S000004801)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000004801
SpoSPAC13G6.06c
ISS
SpoSPAC13G6.06c
GO:0005960 glycine cleavage complex C
ISS
SceS000004801
SpoSPAC13G6.06c
GO:0004375 glycine dehydrogenase (decarboxylating)
activity		 F
IDA
SceS000004801
ISS
SpoSPAC13G6.06c
GO:0006730 one-carbon metabolic process P
IGI
SceS000004801
GO:0019464 glycine decarboxylation via glycine cleavage
system		 P
IEP
SceS000004801
IMP
SceS000004801
ISS
SpoSPAC13G6.06c

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Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk