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Search term: YMR190C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SGS1
SGD link S000004802
Alternative ID YMR190C
Description Nucleolar DNA helicase of the RecQ family involved in genome integrity maintenance; regulates chromosome synapsis and meiotic joint molecule/crossover formation; similar to human BLM and WRN proteins implicated in Bloom and Werner syndromes
Synonyms YMR190C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0351 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING ATP-dependent DNA helicase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g10930 GI:15220248
Arabidopsis thaliana (Ath) At1g27880 GI:15217750
Arabidopsis thaliana (Ath) At1g60930 GI:15219835
Arabidopsis thaliana (Ath) At3g05740 GI:15230040
Arabidopsis thaliana (Ath) At4g35740_2 GI:15237111
Arabidopsis thaliana (Ath) At5g27680 GI:15241024
Caenorhabditis elegans (Cel) CE02651 GI:17536879
Caenorhabditis elegans (Cel) CE13130_2 GI:17538342
Drosophila melanogaster (Dme) 7295152 GI:7295152 Q9VSE6
Drosophila melanogaster (Dme) 7299503 GI:17366114
Homo sapiens (Hsa) Hs4557365
(BLM)
GI:4557365 P54132
Homo sapiens (Hsa) Hs4759030 GI:4759030
Homo sapiens (Hsa) Hs5739524_2 GI:5739524
Saccharomyces cerevisiae (Sce) YMR190c
(S000004802)
GI:6323844 P35187
Schizosaccharomyces pombe (Spo) SPAC212.11 GI:19115952 Q5EAK4
Schizosaccharomyces pombe (Spo) SPAC2G11.12 GI:19114004 Q09811
Encephalitozoon cuniculi (Ecu) ECU07g1130 GI:19074536 Q8SRI7
Arabidopsis thaliana (Ath) At1g10930 GI:15220248
Arabidopsis thaliana (Ath) At1g27880 GI:15217750
Arabidopsis thaliana (Ath) At1g60930 GI:15219835
Arabidopsis thaliana (Ath) At3g05740 GI:15230040
Arabidopsis thaliana (Ath) At4g35740_2 GI:15237111
Arabidopsis thaliana (Ath) At5g27680 GI:15241024
Caenorhabditis elegans (Cel) CE02651 GI:17536879
Caenorhabditis elegans (Cel) CE13130_2 GI:17538342
Drosophila melanogaster (Dme) 7295152 GI:7295152 Q9VSE6
Drosophila melanogaster (Dme) 7299503 GI:17366114
Homo sapiens (Hsa) Hs4557365
(BLM)
GI:4557365 P54132
Homo sapiens (Hsa) Hs4759030 GI:4759030
Homo sapiens (Hsa) Hs5739524_2 GI:5739524
Saccharomyces cerevisiae (Sce) YMR190c
(S000004802)
GI:6323844 P35187
Schizosaccharomyces pombe (Spo) SPAC212.11 GI:19115952 Q5EAK4
Schizosaccharomyces pombe (Spo) SPAC2G11.12 GI:19114004 Q09811
Encephalitozoon cuniculi (Ecu) ECU07g1130 GI:19074536 Q8SRI7
Arabidopsis thaliana (Ath) At1g10930 GI:15220248
Arabidopsis thaliana (Ath) At1g27880 GI:15217750
Arabidopsis thaliana (Ath) At1g60930 GI:15219835
Arabidopsis thaliana (Ath) At3g05740 GI:15230040
Arabidopsis thaliana (Ath) At4g35740_2 GI:15237111
Arabidopsis thaliana (Ath) At5g27680 GI:15241024
Caenorhabditis elegans (Cel) CE02651 GI:17536879
Caenorhabditis elegans (Cel) CE13130_2 GI:17538342
Drosophila melanogaster (Dme) 7295152 GI:7295152 Q9VSE6
Drosophila melanogaster (Dme) 7299503 GI:17366114
Homo sapiens (Hsa) Hs4557365
(BLM)
GI:4557365 P54132
Homo sapiens (Hsa) Hs4759030 GI:4759030
Homo sapiens (Hsa) Hs5739524_2 GI:5739524
Saccharomyces cerevisiae (Sce) YMR190c
(S000004802)
GI:6323844 P35187
Schizosaccharomyces pombe (Spo) SPAC212.11 GI:19115952 Q5EAK4
Schizosaccharomyces pombe (Spo) SPAC2G11.12 GI:19114004 Q09811
Encephalitozoon cuniculi (Ecu) ECU07g1130 GI:19074536 Q8SRI7


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000781 chromosome, telomeric region C
IDA
HsaBLM
SpoSPAC212.11
GO:0000800 lateral element C
IDA
HsaBLM
GO:0005575 cellular_component C
ND
AthAt1g27880
At3g05740
At4g35740
At5g27680
GO:0005634 nucleus C
IDA
HsaBLM
NAS
SpoSPAC212.11
GO:0005730 nucleolus C
IDA
HsaBLM
SceS000004802
GO:0005737 cytoplasm C
IDA
HsaBLM
GO:0016363 nuclear matrix C
IDA
HsaBLM
GO:0016605 PML body C
IDA
HsaBLM
BLM
GO:0031422 RecQ helicase-Topo III complex C
IDA
SceS000004802
SpoSPAC2G11.12
IPI
SceS000004802
GO:0043596 nuclear replication fork C
IC
SpoSPAC2G11.12
GO:0000405 bubble DNA binding F
IDA
HsaBLM
GO:0000739 DNA strand annealing activity F
IDA
HsaBLM
GO:0002039 p53 binding F
IPI
HsaBLM
GO:0003677 DNA binding F
TAS
SpoSPAC2G11.12
GO:0003678 DNA helicase activity F
ISS
AthAt1g60930
GO:0003697 single-stranded DNA binding F
IDA
HsaBLM
GO:0004003 ATP-dependent DNA helicase activity F
IDA
HsaBLM
SceS000004802
GO:0004386 helicase activity F
IDA
HsaBLM
GO:0005515 protein binding F
IPI
HsaBLM
SpoSPAC2G11.12
GO:0005524 ATP binding F
IC
SpoSPAC2G11.12
IDA
HsaBLM
ISS
AthAt4g35740
At1g27880
GO:0008026 ATP-dependent helicase activity F
IDA
AthAt4g35740
HsaBLM
ISS
AthAt3g05740
At1g27880
At1g10930
At4g35740
At5g27680
GO:0009378 four-way junction helicase activity F
IDA
HsaBLM
GO:0016887 ATPase activity F
IDA
HsaBLM
GO:0043140 ATP-dependent 3'-5' DNA helicase
activity
F
IDA
SpoSPAC2G11.12
TAS
SpoSPAC212.11
GO:0051880 G-quadruplex DNA binding F
IDA
HsaBLM
GO:0000070 mitotic sister chromatid segregation P
IMP
SceS000004802
GO:0000079 regulation of cyclin-dependent protein kinase
activity
P
IMP
HsaBLM
GO:0000085 G2 phase of mitotic cell cycle P
NAS
HsaBLM
GO:0000706 meiotic DNA double-strand break
processing
P
IGI
SceS000004802
GO:0000712 resolution of meiotic recombination
intermediates
P
TAS
SpoSPAC2G11.12
GO:0000722 telomere maintenance via recombination P
IEP
SpoSPAC212.11
IGI
SceS000004802
IMP
SceS000004802
GO:0000723 telomere maintenance P
IGI
SpoSPAC2G11.12
IMP
SpoSPAC2G11.12
GO:0000724 double-strand break repair via homologous
recombination
P
IGI
AthAt1g10930
SceS000004802
SpoSPAC2G11.12
IMP
AthAt1g10930
SceS000004802
NAS
HsaBLM
GO:0000725 recombinational repair P
IGI
SpoSPAC2G11.12
GO:0000729 DNA double-strand break processing P
IGI
SceS000004802
GO:0001302 replicative cell aging P
IMP
SceS000004802
GO:0006200 ATP catabolic process P
IDA
SpoSPAC2G11.12
TAS
SpoSPAC212.11
GO:0006260 DNA replication P
RCA
SceS000004802
GO:0006268 DNA unwinding involved in replication P
IDA
SceS000004802
ISS
SpoSPAC2G11.12
GO:0006281 DNA repair P
NAS
HsaBLM
RCA
SceS000004802
GO:0006310 DNA recombination P
IMP
AthAt1g60930
NAS
HsaBLM
RCA
SceS000004802
GO:0006974 response to DNA damage stimulus P
IGI
AthAt1g10930
IMP
AthAt1g10930
HsaBLM
SceS000004802
SpoSPAC2G11.12
RCA
SceS000004802
GO:0007059 chromosome segregation P
IMP
SpoSPAC2G11.12
GO:0007131 reciprocal meiotic recombination P
IMP
SpoSPAC2G11.12
GO:0009650 UV protection P
IMP
SpoSPAC2G11.12
GO:0010165 response to X-ray P
IDA
HsaBLM
GO:0010520 regulation of reciprocal meiotic
recombination
P
IGI
SceS000004802
GO:0010947 negative regulation of meiotic joint molecule
formation
P
IGI
SceS000004802
GO:0030071 regulation of mitotic metaphase/anaphase
transition
P
IMP
SpoSPAC2G11.12
GO:0031292 gene conversion at mating-type locus, DNA
double-strand break processing
P
IGI
SceS000004802
GO:0031297 replication fork processing P
IDA
HsaBLM
TAS
SpoSPAC2G11.12
GO:0031572 G2/M transition DNA damage checkpoint P
NAS
HsaBLM
GO:0031573 intra-S DNA damage checkpoint P
IDA
SpoSPAC2G11.12
IGI
SceS000004802
IMP
SceS000004802
GO:0032508 DNA duplex unwinding P
IDA
SceS000004802
GO:0034065 replication fork processing at rDNA
locus
P
IGI
SpoSPAC2G11.12
GO:0043007 maintenance of rDNA P
IMP
SpoSPAC2G11.12
GO:0045132 meiotic chromosome segregation P
IMP
SceS000004802
GO:0045910 negative regulation of DNA recombination P
IMP
HsaBLM
GO:0045941 positive regulation of transcription P
IDA
HsaBLM
GO:0045950 negative regulation of mitotic
recombination
P
IMP
SpoSPAC2G11.12
GO:0048478 replication fork protection P
NAS
HsaBLM
GO:0051052 regulation of DNA metabolic process P
RCA
SceS000004802
GO:0051259 protein oligomerization P
IDA
HsaBLM
GO:0051276 chromosome organization P
IMP
AthAt1g10930
SceS000004802
GO:0051321 meiotic cell cycle P
RCA
SceS000004802
GO:0051782 negative regulation of cell division P
IMP
HsaBLM
GO:0071140 resolution of mitotic recombination
intermediates
P
IMP
SpoSPAC2G11.12

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
68869

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) hus2 GI:19114004
Saccharomyces cerevisiae (Sce) SGS1
(S000004802)
GI:6323844 P35187
Kluyveromyces lactis (Kla) KLLA0D12694g GI:50307299
Eremothecium gossypii (Ego) AGOS_AFL159W GI:45198362
Arabidopsis thaliana (Ath) RECQI1 GI:30679600
Oryza sativa (Osa) Os11g0672700 GI:115486585