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Search term: YMR205C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PFK2
SGD link S000004818
Alternative ID YMR205C
Description Beta subunit of heterooctameric phosphofructokinase involved in glycolysis, indispensable for anaerobic growth, activated by fructose-2,6-bisphosphate and AMP, mutation inhibits glucose induction of cell cycle-related genes
Synonyms YMR205C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

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Search for GO info:  

GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2440 ACDHYPE

KOGs classification KOGs description
METABOLISM Pyrophosphate-dependent phosphofructo-1-kinase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g12000 GI:15221156
Arabidopsis thaliana (Ath) At1g20950 GI:15218074
Arabidopsis thaliana (Ath) At1g76550 GI:15223082
Arabidopsis thaliana (Ath) At2g22480 GI:15227222
Arabidopsis thaliana (Ath) At4g04040 GI:15233374
Arabidopsis thaliana (Ath) At4g26270 GI:7488164
Arabidopsis thaliana (Ath) At4g29220 GI:15233495
Arabidopsis thaliana (Ath) At4g32840 GI:15233959
Arabidopsis thaliana (Ath) At5g47810 GI:15238818
Arabidopsis thaliana (Ath) At5g56630 GI:10176767
Arabidopsis thaliana (Ath) At5g61580 GI:15240295
Caenorhabditis elegans (Cel) CE05467
(WBGene00008230)
GI:17558788 Q27483
Caenorhabditis elegans (Cel) CE28266
(WBGene00022199)
GI:17570461
Drosophila melanogaster (Dme) 7303792 GI:17647809
Homo sapiens (Hsa) Hs11321601
(PFKP)
GI:11321601 Q01813
Homo sapiens (Hsa) Hs14768802 GI:14768802
Homo sapiens (Hsa) Hs21361070 GI:13623609 P17858
Homo sapiens (Hsa) Hs4505749
(PFKM)
GI:4505749 P08237
Homo sapiens (Hsa) HsM4505747 GI:4505747
Saccharomyces cerevisiae (Sce) YGR240c
(S000003472)
GI:6321679 P16861
Saccharomyces cerevisiae (Sce) YMR205c
(S000004818)
GI:6323861 P16862
Schizosaccharomyces pombe (Spo) SPBC16H5.02 GI:19112738 O42938
Encephalitozoon cuniculi (Ecu) ECU03g0680 GI:19173028 Q8SSA3


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005618 cell wall C
IDA
AthAt1g12000
GO:0005737 cytoplasm C
IDA
SceS000003472
S000004818
SpoSPBC16H5.02
ISS
SpoSPBC16H5.02
GO:0005739 mitochondrion C
IDA
SceS000003472
S000004818
GO:0005829 cytosol C
IDA
AthAt4g26270
At4g32840
At4g29220
At5g47810
At5g56630
SpoSPBC16H5.02
GO:0005886 plasma membrane C
IDA
AthAt4g29220
GO:0005945 6-phosphofructokinase complex C
IDA
HsaPFKM
SpoSPBC16H5.02
IMP
SceS000003472
S000004818
ISS
AthAt4g26270
At4g29220
At2g22480
At4g32840
At5g56630
At5g47810
At5g61580
NAS
HsaPFKP
GO:0009507 chloroplast C
IDA
AthAt5g61580
At2g22480
GO:0010317 pyrophosphate-dependent phosphofructokinase
complex, alpha-subunit complex
C
ISS
AthAt1g20950
At1g76550
GO:0010318 pyrophosphate-dependent phosphofructokinase
complex, beta-subunit complex
C
ISS
AthAt1g12000
At4g04040
GO:0016020 membrane C
IDA
AthAt1g12000
GO:0016324 apical plasma membrane C
IDA
HsaPFKM
GO:0003872 6-phosphofructokinase activity F
IC
SpoSPBC16H5.02
IDA
AthAt4g26270
At4g32840
At4g29220
At5g61580
At5g56630
HsaPFKM
IMP
HsaPFKM
SceS000004818
S000003472
ISS
AthAt4g26270
At4g32840
At4g29220
At5g61580
At2g22480
At5g56630
At5g47810
HsaPFKP
PFKM
SpoSPBC16H5.02
TAS
HsaPFKP
GO:0005515 protein binding F
IPI
HsaPFKP
PFKM
GO:0005524 ATP binding F
IDA
HsaPFKM
SpoSPBC16H5.02
GO:0008022 protein C-terminus binding F
IPI
HsaPFKM
GO:0019900 kinase binding F
IPI
HsaPFKM
GO:0042802 identical protein binding F
IPI
HsaPFKM
GO:0047334 diphosphate-fructose-6-phosphate
1-phosphotransferase activity
F
IMP
AthAt4g04040
At1g20950
At1g12000
At1g76550
ISS
AthAt1g20950
At1g76550
At4g04040
At1g12000
GO:0070061 fructose binding F
IDA
HsaPFKM
GO:0070095 fructose-6-phosphate binding F
IDA
SpoSPBC16H5.02
GO:0000003 reproduction P
IMP
CelWBGene00008230
GO:0006002 fructose 6-phosphate metabolic
process
P
IDA
HsaPFKM
IMP
HsaPFKM
GO:0006096 glycolysis P
IC
SpoSPBC16H5.02
IDA
AthAt4g32840
At5g56630
At4g26270
At5g61580
At4g29220
SceS000003472
S000004818
IMP
HsaPFKM
SceS000003472
S000004818
ISS
AthAt5g56630
At4g26270
At4g04040
At2g22480
At4g29220
At1g12000
At4g32840
At5g47810
At1g76550
At5g61580
SpoSPBC16H5.02
NAS
HsaPFKP
GO:0006417 regulation of translation P
RCA
SceS000004818
S000003472
GO:0009744 response to sucrose stimulus P
IEP
AthAt1g20950
GO:0009749 response to glucose stimulus P
IEP
AthAt1g20950
GO:0009750 response to fructose stimulus P
IEP
AthAt1g20950
GO:0009792 embryo development ending in birth or egg
hatching
P
IMP
CelWBGene00022199
GO:0009793 embryo development ending in seed
dormancy
P
IMP
AthAt4g04040
GO:0015979 photosynthesis P
IMP
AthAt1g12000
At1g20950
At1g76550
At4g04040
GO:0040018 positive regulation of multicellular organism
growth
P
IMP
CelWBGene00008230
GO:0046686 response to cadmium ion P
IEP
AthAt1g12000
GO:0046716 muscle cell homeostasis P
IMP
HsaPFKM
GO:0046835 carbohydrate phosphorylation P
ISS
SpoSPBC16H5.02
GO:0051259 protein oligomerization P
IDA
HsaPFKM

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
55668

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) PFKL GI:48762920
Pan troglodytes (Ptr) PFKL GI:114684642
Canis familiaris (Cfa) PFKL GI:74001533
Mus musculus (Mmu) Pfkl
(MGI:97547)
GI:31560653 P12382
Rattus norvegicus (Rno) Pfkl
(RGD:3311)
GI:6981352 44478
Gallus gallus (Gga) PFKL GI:118094887
Schizosaccharomyces pombe (Spo) pfk1
(SPBC16H5.02)
GI:19112738 O42938
Saccharomyces cerevisiae (Sce) PFK2
(S000004818)
GI:6323861 P16862
Kluyveromyces lactis (Kla) K6P2_KLULA GI:50310683
Eremothecium gossypii (Ego) AGOS_AFL185W GI:45198336
Magnaporthe grisea (Mgr) MGG_02653 GI:145610207
Neurospora crassa (Ncr) NCU00629.1 GI:32408657


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005625 soluble fraction C
ISO
MmuMGI:97547
GO:0005737 cytoplasm C
IDA
SceS000004818
SpoSPBC16H5.02
ISS
SpoSPBC16H5.02
GO:0005739 mitochondrion C
IDA
SceS000004818
GO:0005829 cytosol C
IDA
HsaPFKL
MmuMGI:97547
SpoSPBC16H5.02
ISO
MmuMGI:97547
GO:0005945 6-phosphofructokinase complex C
IDA
HsaPFKL
SpoSPBC16H5.02
IMP
SceS000004818
GO:0003872 6-phosphofructokinase activity F
IC
SpoSPBC16H5.02
IDA
HsaPFKL
MmuMGI:97547
IMP
HsaPFKL
SceS000004818
ISO
MmuMGI:97547
ISS
SpoSPBC16H5.02
GO:0005524 ATP binding F
IDA
HsaPFKL
SpoSPBC16H5.02
ISO
MmuMGI:97547
GO:0019900 kinase binding F
IPI
HsaPFKL
GO:0042802 identical protein binding F
IPI
HsaPFKL
GO:0048029 monosaccharide binding F
ISO
MmuMGI:97547
GO:0070061 fructose binding F
IDA
HsaPFKL
GO:0070095 fructose-6-phosphate binding F
IDA
HsaPFKL
SpoSPBC16H5.02
ISO
MmuMGI:97547
GO:0005975 carbohydrate metabolic process P
ISO
MmuMGI:97547
GO:0006002 fructose 6-phosphate metabolic
process
P
IDA
HsaPFKL
MmuMGI:97547
IMP
HsaPFKL
ISO
MmuMGI:97547
GO:0006096 glycolysis P
IC
SpoSPBC16H5.02
IDA
HsaPFKL
MmuMGI:97547
SceS000004818
IMP
SceS000004818
ISO
MmuMGI:97547
ISS
SpoSPBC16H5.02
GO:0006417 regulation of translation P
RCA
SceS000004818
GO:0009749 response to glucose stimulus P
IDA
MmuMGI:97547
GO:0030388 fructose 1,6-bisphosphate metabolic
process
P
ISO
MmuMGI:97547
GO:0046676 negative regulation of insulin
secretion
P
IDA
MmuMGI:97547
GO:0046835 carbohydrate phosphorylation P
IDA
MmuMGI:97547
ISS
SpoSPBC16H5.02
GO:0051259 protein oligomerization P
IDA
HsaPFKL
GO:0051289 protein homotetramerization P
ISO
MmuMGI:97547

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_170

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga3064 ENSANGP00000021523
Anopheles gambiae (Aga) aga3063 ENSANGP00000025715
Ashbya gossypii (Ago) ago2298 AEL208W
Ashbya gossypii (Ago) ago3010 AFL185W
Arabidopsis thaliana (Ath) ath20621 At4g26270.1
Arabidopsis thaliana (Ath) ath20963 At4g29220.1
Arabidopsis thaliana (Ath) ath21387 At4g32840.1
Arabidopsis thaliana (Ath) ath27675 At5g56630.1
Arabidopsis thaliana (Ath) ath28255 At5g61580.1
Caenorhabditis elegans (Cel) cel20620 Y71H10A.1a
(CE28266;
WBGene00022199)
Candida glabrata (Cgl) cgl1576 CAGL0F08041g
Candida glabrata (Cgl) cgl2768 CAGL0I05698g
Candida glabrata (Cgl) cgl4543 CAGL0L10758g
Cryptococcus neoformans (Cne) cne3869 185.m02455
Dictyostelium discoideum (Ddi) ddi11647 DDB0191364
Debaryomyces hansenii (Dha) dha2791 DEHA0D11132g
Debaryomyces hansenii (Dha) dha6684 DEHA0G22088g
Drosophila melanogaster (Dme) dme4243 CG4001-PA
(FBgn0003071)
Drosophila melanogaster (Dme) dme4244 CG4001-PB
(FBgn0003071)
Drosophila melanogaster (Dme) dme4245 CG4001-PC
(FBgn0003071)
Danio rerio (Dre) dre15601 ENSDARP00000023022
(pfkm)
Q66HV8
Danio rerio (Dre) dre15603 ENSDARP00000029013
(LOC561416)
Danio rerio (Dre) dre15604 ENSDARP00000029635
Danio rerio (Dre) dre15605 ENSDARP00000036894
Danio rerio (Dre) dre15602 ENSDARP00000041218
Escherichia coli (Eco) eco3773 16131754
Encephalitozoon cuniculi (Ecu) ecu435 19173028
Takifugu rubripes (Fru) fru12452 SINFRUP00000145013
Takifugu rubripes (Fru) fru12450 SINFRUP00000145014
Takifugu rubripes (Fru) fru16707 SINFRUP00000145340
Takifugu rubripes (Fru) fru32269 SINFRUP00000154287
Takifugu rubripes (Fru) fru31785 SINFRUP00000162597
Takifugu rubripes (Fru) fru31786 SINFRUP00000162598
Takifugu rubripes (Fru) fru31787 SINFRUP00000167206
Takifugu rubripes (Fru) fru31788 SINFRUP00000167519
Takifugu rubripes (Fru) fru12451 SINFRUP00000171085
Takifugu rubripes (Fru) fru32268 SINFRUP00000173592
Takifugu rubripes (Fru) fru12453 SINFRUP00000174052
Takifugu rubripes (Fru) fru12449 SINFRUP00000176567
Takifugu rubripes (Fru) fru32270 SINFRUP00000176639
Takifugu rubripes (Fru) fru32267 SINFRUP00000176711
Gallus gallus (Gga) gga23357 ENSGALP00000010557
(PFKL)
Gallus gallus (Gga) gga9477 ENSGALP00000011227
Gallus gallus (Gga) gga9476 ENSGALP00000011228
Gallus gallus (Gga) gga9473 ENSGALP00000011230
Gallus gallus (Gga) gga9474 ENSGALP00000011231
Gallus gallus (Gga) gga9475 ENSGALP00000011232
(RCJMB04_33d2)
Q5ZHU4
Gallus gallus (Gga) gga9472 ENSGALP00000011233
(RCJMB04_33d2)
Homo sapiens (Hsa) hsa3436 ENSP00000263145
Homo sapiens (Hsa) hsa21023 ENSP00000269848
(PFKL)
P17858-1
Homo sapiens (Hsa) hsa7399 ENSP00000282439
Homo sapiens (Hsa) hsa21022 ENSP00000309438
(PFKM)
P78457
Homo sapiens (Hsa) hsa7398 ENSP00000345771
(PFKM)
Q6ZTT1
Homo sapiens (Hsa) hsa7397 ENSP00000352842
(PFKM)
P08237-1
Kluyveromyces lactis (Kla) kla242 KLLA0A05544g
Kluyveromyces lactis (Kla) kla4363 KLLA0F06248g
Mus musculus (Mmu) mmu2394 ENSMUSP00000020522
(MGI:97547)
Q8CD98
Mus musculus (Mmu) mmu6486 ENSMUSP00000021614
(MGI:1891833)
Q9WUA3-1
Mus musculus (Mmu) mmu9584 ENSMUSP00000059801
(MGI:97548)
P47857
Neurospora crassa (Ncr) ncr610 NCU00629.2
Oryza sativa (Osa) osa8146 2599.m00146
Oryza sativa (Osa) osa9344 2703.m00136
Oryza sativa (Osa) osa9657 2709.m00161
Oryza sativa (Osa) osa25118 3878.m00218
Oryza sativa (Osa) osa48409 5815.m00186
Oryza sativa (Osa) osa63612 6626.m00119
Rattus norvegicus (Rno) rno17705 ENSRNOP00000001625
(RGD:3311)
P30835
Rattus norvegicus (Rno) rno27679 ENSRNOP00000013374
(RGD:68419)
P47858
Rattus norvegicus (Rno) rno13552 ENSRNOP00000023252
(RGD:61893)
P47860
Saccharomyces cerevisiae (Sce) sce2621 YGR240C
(S000003472)
Saccharomyces cerevisiae (Sce) sce4974 YMR205C
(S000004818)
Schizosaccharomyces pombe (Spo) spo4721 SPBC16H5.02 O42938
Yarrowia lipolytica (Yli) yli3384 YALI0D16357g