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Search term: YMR216C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SKY1
SGD link S000004829
Alternative ID YMR216C
Description SR protein kinase (SRPK) involved in regulating proteins involved in mRNA metabolism and cation homeostasis; similar to human SRPK1
Synonyms YMR216C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1290 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Serine/threonine protein kinase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g17530 GI:15227856
Arabidopsis thaliana (Ath) At3g44850 GI:15230526
Arabidopsis thaliana (Ath) At3g53030 GI:11259819
Arabidopsis thaliana (Ath) At4g35500 GI:15237030
Arabidopsis thaliana (Ath) At5g22840 GI:15237143
Caenorhabditis elegans (Cel) CE02949 GI:17554862
Caenorhabditis elegans (Cel) CE20457 GI:17554858
Caenorhabditis elegans (Cel) CE20458 GI:17554860
Drosophila melanogaster (Dme) 7293139 GI:7293139 Q9VXN5
Drosophila melanogaster (Dme) 7296535 GI:7296535
Drosophila melanogaster (Dme) 7303073 GI:7303073
Homo sapiens (Hsa) Hs15834624 GI:15834624
Homo sapiens (Hsa) Hs17466653 GI:17466653
Homo sapiens (Hsa) Hs22050383 GI:22050383
Homo sapiens (Hsa) Hs4507221 GI:4507221
Homo sapiens (Hsa) Hs7657629 GI:7657629
Saccharomyces cerevisiae (Sce) YMR216c
(S000004829)		 GI:6323872 Q03656
Schizosaccharomyces pombe (Spo) SPBC530.14c GI:19112119 P36616


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt4g35500
At3g44850
At3g53030
At5g22840
At2g17530
GO:0005634 nucleus C
IDA
SpoSPBC530.14c
GO:0005737 cytoplasm C
IDA
SceS000004829
SpoSPBC530.14c
GO:0005816 spindle pole body C
IDA
SpoSPBC530.14c
GO:0005829 cytosol C
IDA
SpoSPBC530.14c
GO:0032153 cell division site C
IDA
SpoSPBC530.14c
GO:0004672 protein kinase activity F
IDA
AthAt3g53030
GO:0004674 protein serine/threonine kinase
activity		 F
IDA
SceS000004829
SpoSPBC530.14c
GO:0005515 protein binding F
IPI
SpoSPBC530.14c
GO:0016301 kinase activity F
ISS
AthAt5g22840
At2g17530
At3g53030
At4g35500
At3g44850
GO:0006376 mRNA splice site selection P
IGI
SceS000004829
GO:0006468 protein amino acid phosphorylation P
IDA
AthAt3g53030
SceS000004829
SpoSPBC530.14c
GO:0006873 cellular ion homeostasis P
IMP
SceS000004829
GO:0006979 response to oxidative stress P
IDA
AthAt3g53030
GO:0007243 intracellular protein kinase cascade P
NAS
SpoSPBC530.14c
GO:0007346 regulation of mitotic cell cycle P
IGI
SpoSPBC530.14c
GO:0008361 regulation of cell size P
IMP
SceS000004829
GO:0016073 snRNA metabolic process P
RCA
SceS000004829
GO:0030003 cellular cation homeostasis P
IMP
SceS000004829
GO:0042307 positive regulation of protein import into
nucleus		 P
IMP
SceS000004829
GO:0042493 response to drug P
IMP
SceS000004829
GO:0048024 regulation of nuclear mRNA splicing, via
spliceosome		 P
IGI
SpoSPBC530.14c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
110962

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) SRPK1 GI:47419936
Pan troglodytes (Ptr) SRPK1 GI:114607104
Canis familiaris (Cfa) SRPK1 GI:73972670
Mus musculus (Mmu) Srpk1
(MGI:106908)		 GI:31982726 O70551
Rattus norvegicus (Rno) Srpk1
(RGD:1308272)		 GI:71043650
Gallus gallus (Gga) SRPK1 GI:118102284
Drosophila melanogaster (Dme) SRPK
(FBgn0026370)		 GI:24653849
Anopheles gambiae (Aga) AgaP_AGAP005322 GI:158293984
Caenorhabditis elegans (Cel) spk-1
(CE36580;
WBGene00004980)		 GI:71980905
Schizosaccharomyces pombe (Spo) dsk1
(SPBC530.14c)		 GI:19112119 P36616
Saccharomyces cerevisiae (Sce) SKY1
(S000004829)		 GI:6323872 Q03656
Kluyveromyces lactis (Kla) KLLA0C07216g GI:50305123
Eremothecium gossypii (Ego) AGOS_AER348C GI:45190950
Magnaporthe grisea (Mgr) MGG_10596 GI:145614791
Neurospora crassa (Ncr) NCU09202.1 GI:32422301
Arabidopsis thaliana (Ath) AT4G35500 GI:42573185
Arabidopsis thaliana (Ath) AT2G17530 GI:15227856
Oryza sativa (Osa) Os09g0552300 GI:115480559
Plasmodium falciparum (Pfa) MAL3P1.1 GI:124504711


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt4g35500
At2g17530
GO:0005634 nucleus C
IDA
HsaSRPK1
SpoSPBC530.14c
GO:0005737 cytoplasm C
IDA
HsaSRPK1
SceS000004829
SpoSPBC530.14c
GO:0005816 spindle pole body C
IDA
SpoSPBC530.14c
GO:0005829 cytosol C
IDA
SpoSPBC530.14c
GO:0032153 cell division site C
IDA
SpoSPBC530.14c
GO:0000287 magnesium ion binding F
IDA
HsaSRPK1
MmuMGI:106908
GO:0004672 protein kinase activity F
ISS
DmeFBgn0026370
NAS
DmeFBgn0026370
TAS
DmeFBgn0026370
HsaSRPK1
GO:0004674 protein serine/threonine kinase
activity		 F
IDA
HsaSRPK1
MmuMGI:106908
SceS000004829
SpoSPBC530.14c
ISS
DmeFBgn0026370
GO:0005515 protein binding F
IPI
HsaSRPK1
MmuMGI:106908
SpoSPBC530.14c
GO:0005524 ATP binding F
IDA
HsaSRPK1
MmuMGI:106908
GO:0016301 kinase activity F
ISS
AthAt2g17530
At4g35500
GO:0000003 reproduction P
IMP
CelWBGene00004980
GO:0000910 cytokinesis P
IMP
CelWBGene00004980
GO:0002119 nematode larval development P
IMP
CelWBGene00004980
GO:0006376 mRNA splice site selection P
IGI
SceS000004829
GO:0006468 protein amino acid phosphorylation P
IDA
HsaSRPK1
MmuMGI:106908
SceS000004829
SpoSPBC530.14c
TAS
DmeFBgn0026370
GO:0006873 cellular ion homeostasis P
IMP
SceS000004829
GO:0007059 chromosome segregation P
IDA
HsaSRPK1
GO:0007243 intracellular protein kinase cascade P
IDA
HsaSRPK1
MmuMGI:106908
NAS
SpoSPBC530.14c
GO:0007276 gamete generation P
IMP
CelWBGene00004980
GO:0007346 regulation of mitotic cell cycle P
IGI
SpoSPBC530.14c
GO:0008361 regulation of cell size P
IMP
SceS000004829
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00004980
GO:0016073 snRNA metabolic process P
RCA
SceS000004829
GO:0030003 cellular cation homeostasis P
IMP
SceS000004829
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00004980
GO:0042307 positive regulation of protein import into
nucleus		 P
IMP
SceS000004829
GO:0042493 response to drug P
IMP
SceS000004829
GO:0048024 regulation of nuclear mRNA splicing, via
spliceosome		 P
IGI
SpoSPBC530.14c
GO:0050684 regulation of mRNA processing P
IDA
HsaSRPK1
MmuMGI:106908
GO:0051729 germline cell cycle switching, mitotic to meiotic
cell cycle		 P
IMP
CelWBGene00004980

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_267

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga731 ENSANGP00000006891
Ashbya gossypii (Ago) ago2849 AER348C
Arabidopsis thaliana (Ath) ath8597 At2g17530.1
Arabidopsis thaliana (Ath) ath15758 At3g44850.1
Arabidopsis thaliana (Ath) ath16643 At3g53030.1
Arabidopsis thaliana (Ath) ath21706 At4g35500.1
Arabidopsis thaliana (Ath) ath21707 At4g35500.2
Arabidopsis thaliana (Ath) ath24522 At5g22840.1
Caenorhabditis elegans (Cel) cel516 B0464.5a
(CE36580;
WBGene00004980)
Caenorhabditis elegans (Cel) cel517 B0464.5b
(CE20457)
Caenorhabditis elegans (Cel) cel518 B0464.5c
(CE36373)
Candida glabrata (Cgl) cgl1398 CAGL0F03905g
Cryptococcus neoformans (Cne) cne3287 167.m05816
Dictyostelium discoideum (Ddi) ddi11700 DDB0230135
Debaryomyces hansenii (Dha) dha1177 DEHA0B11528g
Debaryomyces hansenii (Dha) dha3073 DEHA0D17237g
Drosophila melanogaster (Dme) dme10708 CG11489-PB
(FBgn0025702)
Drosophila melanogaster (Dme) dme10707 CG11489-PC
(FBgn0025702)
Drosophila melanogaster (Dme) dme5230 CG8174-PA
(FBgn0026370)
Drosophila melanogaster (Dme) dme5231 CG8174-PB
(FBgn0026370)
Drosophila melanogaster (Dme) dme5232 CG8174-PC
(FBgn0026370)
Danio rerio (Dre) dre26773 ENSDARP00000023666
(LOC572238)
Danio rerio (Dre) dre22470 ENSDARP00000043903
Danio rerio (Dre) dre22664 ENSDARP00000045195
Takifugu rubripes (Fru) fru8278 SINFRUP00000134023
Takifugu rubripes (Fru) fru8277 SINFRUP00000134024
Takifugu rubripes (Fru) fru32290 SINFRUP00000154317
Takifugu rubripes (Fru) fru11692 SINFRUP00000161558
Takifugu rubripes (Fru) fru5899 SINFRUP00000161559
Takifugu rubripes (Fru) fru5897 SINFRUP00000161560
Takifugu rubripes (Fru) fru23140 SINFRUP00000164832
Takifugu rubripes (Fru) fru23141 SINFRUP00000164833
Takifugu rubripes (Fru) fru23142 SINFRUP00000164834
Takifugu rubripes (Fru) fru32288 SINFRUP00000165844
Takifugu rubripes (Fru) fru5898 SINFRUP00000166377
Takifugu rubripes (Fru) fru8279 SINFRUP00000168495
Takifugu rubripes (Fru) fru32291 SINFRUP00000175853
Takifugu rubripes (Fru) fru32289 SINFRUP00000176864
Gallus gallus (Gga) gga16405 ENSGALP00000001303
Gallus gallus (Gga) gga16406 ENSGALP00000001304
Gallus gallus (Gga) gga16407 ENSGALP00000001305
Gallus gallus (Gga) gga16404 ENSGALP00000001306
(SRPK1)
Gallus gallus (Gga) gga138 ENSGALP00000013230
(SRPK2)
Gallus gallus (Gga) gga139 ENSGALP00000013231
Gallus gallus (Gga) gga140 ENSGALP00000013232
Gallus gallus (Gga) gga141 ENSGALP00000013233
Gallus gallus (Gga) gga137 ENSGALP00000013236
Homo sapiens (Hsa) hsa29241 ENSP00000337679
(SRPK2)		 A6NF09
Homo sapiens (Hsa) hsa27019 ENSP00000339450
(SRPK1)		 C9J8N4
Homo sapiens (Hsa) hsa29240 ENSP00000342672
Homo sapiens (Hsa) hsa29242 ENSP00000349863
(SRPK2)		 P78362
Homo sapiens (Hsa) hsa27018 ENSP00000354674
(SRPK1)		 Q96SB4-2
Kluyveromyces lactis (Kla) kla1519 KLLA0C07216g
Mus musculus (Mmu) mmu29135 ENSMUSP00000002081
(MGI:1891338)		 Q9Z0G2
Mus musculus (Mmu) mmu11288 ENSMUSP00000004987
(MGI:106908)		 O70551
Mus musculus (Mmu) mmu19739 ENSMUSP00000030859
Neurospora crassa (Ncr) ncr8969 NCU09202.2
Oryza sativa (Osa) osa5289 2186.m00110
Oryza sativa (Osa) osa48612 5671.m00104
Oryza sativa (Osa) osa47388 5778.m00027
Oryza sativa (Osa) osa51375 5976.m00183
Oryza sativa (Osa) osa59459 6523.m00180
Plasmodium falciparum (Pfa) pfa2676 PFC0105w
Rattus norvegicus (Rno) rno17601 ENSRNOP00000000612
(RGD:1308272)		 Q4KLN3
Rattus norvegicus (Rno) rno20636 ENSRNOP00000014307
(RGD:1305107)
Saccharomyces cerevisiae (Sce) sce4985 YMR216C
(S000004829)
Schizosaccharomyces pombe (Spo) spo3037 SPBC530.14c P36616
Yarrowia lipolytica (Yli) yli620 YALI0A18590g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt4g35500
At3g44850
At3g53030
At5g22840
At2g17530
GO:0005634 nucleus C
IDA
SpoSPBC530.14c
GO:0005737 cytoplasm C
IDA
SceS000004829
SpoSPBC530.14c
GO:0005816 spindle pole body C
IDA
SpoSPBC530.14c
GO:0005829 cytosol C
IDA
SpoSPBC530.14c
GO:0032153 cell division site C
IDA
SpoSPBC530.14c
GO:0048786 presynaptic active zone C
IDA
DmeFBgn0025702
FBgn0025702
GO:0000287 magnesium ion binding F
IDA
MmuMGI:106908
GO:0004672 protein kinase activity F
IDA
AthAt3g53030
DmeFBgn0025702
ISS
DmeFBgn0026370
FBgn0025702
NAS
DmeFBgn0026370
FBgn0025702
TAS
DmeFBgn0026370
GO:0004674 protein serine/threonine kinase
activity		 F
IDA
MmuMGI:106908
MGI:1891338
SceS000004829
SpoSPBC530.14c
ISS
DmeFBgn0026370
FBgn0025702
GO:0005515 protein binding F
IPI
MmuMGI:106908
SpoSPBC530.14c
GO:0005524 ATP binding F
IDA
MmuMGI:106908
GO:0016301 kinase activity F
ISS
AthAt5g22840
At2g17530
At3g53030
At4g35500
At3g44850
GO:0000003 reproduction P
IMP
CelWBGene00004980
GO:0000910 cytokinesis P
IMP
CelWBGene00004980
GO:0002119 nematode larval development P
IMP
CelWBGene00004980
GO:0006376 mRNA splice site selection P
IGI
SceS000004829
GO:0006468 protein amino acid phosphorylation P
IDA
AthAt3g53030
DmeFBgn0025702
MmuMGI:106908
MGI:1891338
SceS000004829
SpoSPBC530.14c
NAS
DmeFBgn0025702
TAS
DmeFBgn0026370
GO:0006873 cellular ion homeostasis P
IMP
SceS000004829
GO:0006979 response to oxidative stress P
IDA
AthAt3g53030
GO:0007243 intracellular protein kinase cascade P
IDA
MmuMGI:106908
NAS
SpoSPBC530.14c
GO:0007268 synaptic transmission P
IMP
DmeFBgn0025702
GO:0007276 gamete generation P
IMP
CelWBGene00004980
GO:0007346 regulation of mitotic cell cycle P
IGI
SpoSPBC530.14c
GO:0007519 skeletal muscle tissue development P
IMP
MmuMGI:1891338
GO:0008361 regulation of cell size P
IMP
SceS000004829
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00004980
GO:0016073 snRNA metabolic process P
RCA
SceS000004829
GO:0030003 cellular cation homeostasis P
IMP
SceS000004829
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00004980
GO:0042307 positive regulation of protein import into
nucleus		 P
IMP
SceS000004829
GO:0042493 response to drug P
IMP
SceS000004829
GO:0048024 regulation of nuclear mRNA splicing, via
spliceosome		 P
IGI
SpoSPBC530.14c
GO:0048789 cytoskeletal matrix organization at active
zone		 P
IMP
DmeFBgn0025702
GO:0050684 regulation of mRNA processing P
IDA
MmuMGI:106908
GO:0051729 germline cell cycle switching, mitotic to meiotic
cell cycle		 P
IMP
CelWBGene00004980

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC530.14c
(P36616)		 YMR216C
(S000004829)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPBC530.14c
GO:0005737 cytoplasm C
IDA
SceS000004829
SpoSPBC530.14c
GO:0005816 spindle pole body C
IDA
SpoSPBC530.14c
GO:0005829 cytosol C
IDA
SpoSPBC530.14c
GO:0032153 cell division site C
IDA
SpoSPBC530.14c
GO:0004674 protein serine/threonine kinase
activity		 F
IDA
SceS000004829
SpoSPBC530.14c
GO:0005515 protein binding F
IPI
SpoSPBC530.14c
GO:0006376 mRNA splice site selection P
IGI
SceS000004829
GO:0006468 protein amino acid phosphorylation P
IDA
SceS000004829
SpoSPBC530.14c
GO:0006873 cellular ion homeostasis P
IMP
SceS000004829
GO:0007243 intracellular protein kinase cascade P
NAS
SpoSPBC530.14c
GO:0007346 regulation of mitotic cell cycle P
IGI
SpoSPBC530.14c
GO:0008361 regulation of cell size P
IMP
SceS000004829
GO:0016073 snRNA metabolic process P
RCA
SceS000004829
GO:0030003 cellular cation homeostasis P
IMP
SceS000004829
GO:0042307 positive regulation of protein import into
nucleus		 P
IMP
SceS000004829
GO:0042493 response to drug P
IMP
SceS000004829
GO:0048024 regulation of nuclear mRNA splicing, via
spliceosome		 P
IGI
SpoSPBC530.14c

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