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Search term: YMR217W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name GUA1
SGD link S000004830
Alternative ID YMR217W
Description GMP synthase, an enzyme that catalyzes the second step in the biosynthesis of GMP from inosine 5'-phosphate (IMP); transcription is not subject to regulation by guanine but is negatively regulated by nutrient starvation
Synonyms YMR217W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1622 ACDHYP-

KOGs classification KOGs description
METABOLISM GMP synthase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g63660 GI:15222505
Caenorhabditis elegans (Cel) CE18084
(WBGene00010912)		 GI:17535203
Drosophila melanogaster (Dme) 7298764 GI:7298764
Homo sapiens (Hsa) Hs4504035
(GMPS)		 GI:4504035 P49915
Homo sapiens (Hsa) Hs20475940 GI:20475940
Homo sapiens (Hsa) Hs20541899 GI:20541899
Saccharomyces cerevisiae (Sce) YMR217w
(S000004830)		 GI:6323873 P38625
Schizosaccharomyces pombe (Spo) SPAP7G5.02c GI:19115224 Q9P772


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
SceS000004830
GO:0005829 cytosol C
IDA
SpoSPAP7G5.02c
GO:0003922 GMP synthase (glutamine-hydrolyzing)
activity		 F
IMP
SceS000004830
ISS
AthAt1g63660
SceS000004830
SpoSPAP7G5.02c
GO:0006177 GMP biosynthetic process P
ISS
SpoSPAP7G5.02c
GO:0009113 purine base biosynthetic process P
TAS
HsaGMPS
GO:0009168 purine ribonucleoside monophosphate biosynthetic
process		 P
EXP
HsaGMPS
GO:0046037 GMP metabolic process P
TAS
SceS000004830

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
68870

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) gua2
(SPAP7G5.02c)		 GI:19115224 Q9P772
Saccharomyces cerevisiae (Sce) GUA1
(S000004830)		 GI:6323873 P38625
Kluyveromyces lactis (Kla) KLLA0C07172g GI:50305119
Eremothecium gossypii (Ego) AGOS_AER350W GI:45190952
Magnaporthe grisea (Mgr) MGG_00919 GI:39973869
Neurospora crassa (Ncr) NCU02325.1 GI:32421315
Arabidopsis thaliana (Ath) AT1G63660 GI:15222505
Oryza sativa (Osa) Os08g0326600 GI:115475912
Plasmodium falciparum (Pfa) PF10_0123 GI:124802227


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
PfaPF10_0123
SceS000004830
GO:0005829 cytosol C
IDA
SpoSPAP7G5.02c
GO:0003921 GMP synthase activity F
ISS
PfaPF10_0123
GO:0003922 GMP synthase (glutamine-hydrolyzing)
activity		 F
IMP
SceS000004830
ISS
AthAt1g63660
SceS000004830
SpoSPAP7G5.02c
GO:0006177 GMP biosynthetic process P
ISS
SpoSPAP7G5.02c
GO:0046037 GMP metabolic process P
TAS
SceS000004830

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_620

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga12427 ENSANGP00000012372
Ashbya gossypii (Ago) ago2851 AER350W
Arabidopsis thaliana (Ath) ath5569 At1g63660.1
Arabidopsis thaliana (Ath) ath5570 At1g63660.2
Caenorhabditis elegans (Cel) cel12981 M106.4a
(CE18084;
WBGene00010912)
Caenorhabditis elegans (Cel) cel12982 M106.4b
(CE35897)
Candida glabrata (Cgl) cgl1399 CAGL0F03927g
Cryptococcus neoformans (Cne) cne3620 176.m02354
Dictyostelium discoideum (Ddi) ddi12423 DDB0215334
Debaryomyces hansenii (Dha) dha4922 DEHA0F12122g
Drosophila melanogaster (Dme) dme3228 CG9242-PA
(FBgn0000239)
Danio rerio (Dre) dre26375 ENSDARP00000044197
Danio rerio (Dre) dre26374 ENSDARP00000047125
(zgc:153764)		 Q08BG8
Escherichia coli (Eco) eco2428 16130432
Takifugu rubripes (Fru) fru7852 SINFRUP00000159883
Gallus gallus (Gga) gga23789 ENSGALP00000016710
Gallus gallus (Gga) gga23787 ENSGALP00000016711
(GMPS)		 Q5ZI61
Gallus gallus (Gga) gga23790 ENSGALP00000016712
Gallus gallus (Gga) gga23791 ENSGALP00000016713
Gallus gallus (Gga) gga23792 ENSGALP00000016714
Gallus gallus (Gga) gga23788 ENSGALP00000016715
Homo sapiens (Hsa) hsa23352 ENSP00000295920
Kluyveromyces lactis (Kla) kla1517 KLLA0C07172g
Mus musculus (Mmu) mmu16699 ENSMUSP00000029405
(MGI:2448526)		 Q3THK7
Mus musculus (Mmu) mmu16701 ENSMUSP00000059329
Mus musculus (Mmu) mmu16700 ENSMUSP00000075512
Neurospora crassa (Ncr) ncr2260 NCU02325.2
Oryza sativa (Osa) osa15258 3030.m00093
Oryza sativa (Osa) osa48581 5821.m00104
Plasmodium falciparum (Pfa) pfa344 PF10_0123
Saccharomyces cerevisiae (Sce) sce4986 YMR217W
(S000004830)
Schizosaccharomyces pombe (Spo) spo796 SPAP7G5.02c Q9P772
Yarrowia lipolytica (Yli) yli1414 YALI0B16104g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
PfaPF10_0123
SceS000004830
GO:0005829 cytosol C
IDA
SpoSPAP7G5.02c
ISO
MmuMGI:2448526
GO:0003921 GMP synthase activity F
ISO
MmuMGI:2448526
ISS
DmeFBgn0000239
PfaPF10_0123
GO:0003922 GMP synthase (glutamine-hydrolyzing)
activity		 F
IMP
SceS000004830
ISO
MmuMGI:2448526
ISS
AthAt1g63660
DmeFBgn0000239
SceS000004830
SpoSPAP7G5.02c
GO:0019899 enzyme binding F
ISO
MmuMGI:2448526
GO:0006177 GMP biosynthetic process P
ISO
MmuMGI:2448526
ISS
DmeFBgn0000239
SpoSPAP7G5.02c
GO:0007411 axon guidance P
IMP
DmeFBgn0000239
GO:0016578 histone deubiquitination P
IPI
DmeFBgn0000239
GO:0046037 GMP metabolic process P
TAS
SceS000004830

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAP7G5.02c
(Q9P772)		 YMR217W
(S000004830)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
SceS000004830
GO:0005829 cytosol C
IDA
SpoSPAP7G5.02c
GO:0003922 GMP synthase (glutamine-hydrolyzing)
activity		 F
IMP
SceS000004830
ISS
SceS000004830
SpoSPAP7G5.02c
GO:0006177 GMP biosynthetic process P
ISS
SpoSPAP7G5.02c
GO:0046037 GMP metabolic process P
TAS
SceS000004830

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