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Search term: YMR220W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ERG8
SGD link S000004833
Alternative ID YMR220W
Description Phosphomevalonate kinase, an essential cytosolic enzyme that acts in the biosynthesis of isoprenoids and sterols, including ergosterol, from mevalonate
Synonyms YMR220W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG4519 A---YP-

KOGs classification KOGs description
METABOLISM Phosphomevalonate kinase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g31910 GI:15222502
Saccharomyces cerevisiae (Sce) YMR220w
(S000004833)		 GI:6323876 P24521
Schizosaccharomyces pombe (Spo) SPAC343.01c GI:19114333 Q9UT88


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000004833
SpoSPAC343.01c
GO:0005737 cytoplasm C
IDA
SceS000004833
GO:0005739 mitochondrion C
IDA
SpoSPAC343.01c
GO:0005829 cytosol C
IDA
SpoSPAC343.01c
ISS
SpoSPAC343.01c
GO:0004631 phosphomevalonate kinase activity F
IMP
SceS000004833
ISS
SpoSPAC343.01c
GO:0006066 alcohol metabolic process P
RCA
SceS000004833
GO:0006696 ergosterol biosynthetic process P
IMP
SceS000004833
ISS
SpoSPAC343.01c
GO:0010142 farnesyl diphosphate biosynthetic process,
mevalonate pathway		 P
IMP
SceS000004833
GO:0019287 isopentenyl diphosphate biosynthetic process,
mevalonate pathway		 P
IMP
SceS000004833
GO:0031388 organic acid phosphorylation P
IMP
SceS000004833
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000004833

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
6666

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) erg8
(SPAC343.01c)		 GI:63054542 Q9UT88
Saccharomyces cerevisiae (Sce) ERG8
(S000004833)		 GI:6323876 P24521
Kluyveromyces lactis (Kla) KLLA0C07084g GI:50305111
Eremothecium gossypii (Ego) AGOS_AER354W GI:45190956
Magnaporthe grisea (Mgr) MGG_05812 GI:39976529
Neurospora crassa (Ncr) NCU08671.1 GI:32418634
Arabidopsis thaliana (Ath) AT1G31910 GI:15222502
Oryza sativa (Osa) Os03g0253100 GI:115451953


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000004833
SpoSPAC343.01c
GO:0005737 cytoplasm C
IDA
SceS000004833
GO:0005739 mitochondrion C
IDA
SpoSPAC343.01c
GO:0005829 cytosol C
IDA
SpoSPAC343.01c
ISS
SpoSPAC343.01c
GO:0004631 phosphomevalonate kinase activity F
IMP
SceS000004833
ISS
SpoSPAC343.01c
GO:0006066 alcohol metabolic process P
RCA
SceS000004833
GO:0006696 ergosterol biosynthetic process P
IMP
SceS000004833
ISS
SpoSPAC343.01c
GO:0010142 farnesyl diphosphate biosynthetic process,
mevalonate pathway		 P
IMP
SceS000004833
GO:0019287 isopentenyl diphosphate biosynthetic process,
mevalonate pathway		 P
IMP
SceS000004833
GO:0031388 organic acid phosphorylation P
IMP
SceS000004833
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000004833

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_7864

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago2855 AER354W
Arabidopsis thaliana (Ath) ath3337 At1g31910.1
Candida glabrata (Cgl) cgl1402 CAGL0F03993g
Cryptococcus neoformans (Cne) cne1692 164.m01650
Dictyostelium discoideum (Ddi) ddi11200 DDB0184512
Debaryomyces hansenii (Dha) dha6575 DEHA0G19569g
Kluyveromyces lactis (Kla) kla1513 KLLA0C07084g
Neurospora crassa (Ncr) ncr8452 NCU08671.2
Oryza sativa (Osa) osa70499 7143.m00143
Saccharomyces cerevisiae (Sce) sce4989 YMR220W
(S000004833)
Schizosaccharomyces pombe (Spo) spo4078 SPAC343.01c Q9UT88
Yarrowia lipolytica (Yli) yli4123 YALI0E06193g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000004833
SpoSPAC343.01c
GO:0005737 cytoplasm C
IDA
SceS000004833
GO:0005739 mitochondrion C
IDA
SpoSPAC343.01c
GO:0005829 cytosol C
IDA
SpoSPAC343.01c
ISS
SpoSPAC343.01c
GO:0004631 phosphomevalonate kinase activity F
IMP
SceS000004833
ISS
SpoSPAC343.01c
GO:0006066 alcohol metabolic process P
RCA
SceS000004833
GO:0006696 ergosterol biosynthetic process P
IMP
SceS000004833
ISS
SpoSPAC343.01c
GO:0010142 farnesyl diphosphate biosynthetic process,
mevalonate pathway		 P
IMP
SceS000004833
GO:0019287 isopentenyl diphosphate biosynthetic process,
mevalonate pathway		 P
IMP
SceS000004833
GO:0031388 organic acid phosphorylation P
IMP
SceS000004833
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000004833

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC343.01c
(Q9UT88)		 YMR220W
(S000004833)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000004833
SpoSPAC343.01c
GO:0005737 cytoplasm C
IDA
SceS000004833
GO:0005739 mitochondrion C
IDA
SpoSPAC343.01c
GO:0005829 cytosol C
IDA
SpoSPAC343.01c
ISS
SpoSPAC343.01c
GO:0004631 phosphomevalonate kinase activity F
IMP
SceS000004833
ISS
SpoSPAC343.01c
GO:0006066 alcohol metabolic process P
RCA
SceS000004833
GO:0006696 ergosterol biosynthetic process P
IMP
SceS000004833
ISS
SpoSPAC343.01c
GO:0010142 farnesyl diphosphate biosynthetic process,
mevalonate pathway		 P
IMP
SceS000004833
GO:0019287 isopentenyl diphosphate biosynthetic process,
mevalonate pathway		 P
IMP
SceS000004833
GO:0031388 organic acid phosphorylation P
IMP
SceS000004833
GO:0043094 cellular metabolic compound salvage P
RCA
SceS000004833

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