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Search term: YMR260C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name TIF11
SGD link S000004873
Alternative ID YMR260C
Description Translation initiation factor eIF1A, essential protein that forms a complex with Sui1p (eIF1) and the 40S ribosomal subunit and scans for the start codon; C-terminus associates with Fun12p (eIF5B); N terminus interacts with eIF2 and eIF3
Synonyms YMR260C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3403 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Translation initiation factor 1A (eIF-1A)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g04520 GI:15228152
Arabidopsis thaliana (Ath) At5g35680 GI:15238583
Caenorhabditis elegans (Cel) CE17962
(WBGene00019162)		 GI:17540984 Q9TXU7
Drosophila melanogaster (Dme) 7300367 GI:7300367 Q9VEA1
Homo sapiens (Hsa) Hs4503499
(EIF1AX)		 GI:4503499 P47813
Homo sapiens (Hsa) Hs4758254 GI:4758254
Saccharomyces cerevisiae (Sce) YMR260c
(S000004873)		 GI:6323916 P38912
Schizosaccharomyces pombe (Spo) SPBC25H2.07 GI:19113151 P55877
Encephalitozoon cuniculi (Ecu) ECU04g1170 GI:19074195 Q8SS25


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt2g04520
At5g35680
GO:0005634 nucleus C
IDA
SpoSPBC25H2.07
GO:0005737 cytoplasm C
IDA
HsaEIF1AX
GO:0005829 cytosol C
EXP
HsaEIF1AX
IDA
SpoSPBC25H2.07
GO:0005840 ribosome C
ISS
SpoSPBC25H2.07
TAS
SceS000004873
GO:0003725 double-stranded RNA binding F
IDA
SceS000004873
ISS
SpoSPBC25H2.07
GO:0003743 translation initiation factor activity F
ISS
AthAt5g35680
At2g04520
SpoSPBC25H2.07
TAS
SceS000004873
GO:0008135 translation factor activity, nucleic acid
binding		 F
TAS
HsaEIF1AX
GO:0033592 RNA strand annealing activity F
IDA
SpoSPBC25H2.07
GO:0000003 reproduction P
IMP
CelWBGene00019162
GO:0006413 translational initiation P
ISS
AthAt5g35680
At2g04520
SpoSPBC25H2.07
TAS
HsaEIF1AX
SceS000004873
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00019162
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00019162
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00019162
GO:0040011 locomotion P
IMP
CelWBGene00019162
GO:0040018 positive regulation of multicellular organism
growth		 P
IMP
CelWBGene00019162
GO:0045948 positive regulation of translational
initiation		 P
ISS
SpoSPBC25H2.07

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
20364

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) EIF1AX GI:4503499 P47813
Canis familiaris (Cfa) EIF1AX GI:74007185
Mus musculus (Mmu) Eif1ay
(MGI:1913485)		 GI:31541824 Q8BMJ3
Rattus norvegicus (Rno) Eif1ay GI:27708964
Schizosaccharomyces pombe (Spo) tif11
(SPBC25H2.07)		 GI:19113151 P55877
Saccharomyces cerevisiae (Sce) TIF11
(S000004873)		 GI:6323916 P38912
Kluyveromyces lactis (Kla) KLLA0E11253g GI:50308905
Eremothecium gossypii (Ego) AGOS_AER275C GI:45190878
Neurospora crassa (Ncr) NCU07437.1 GI:32414487
Arabidopsis thaliana (Ath) AT5G35680 GI:15238583
Arabidopsis thaliana (Ath) AT2G04520 GI:15228152
Oryza sativa (Osa) Os06g0342200 GI:115467944
Oryza sativa (Osa) Os02g0300700 GI:115445679
Plasmodium falciparum (Pfa) PF11_0447 GI:124804794


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt2g04520
At5g35680
MmuMGI:1913485
GO:0005634 nucleus C
IDA
SpoSPBC25H2.07
GO:0005737 cytoplasm C
IDA
HsaEIF1AX
GO:0005829 cytosol C
EXP
HsaEIF1AX
IDA
SpoSPBC25H2.07
GO:0005840 ribosome C
ISS
SpoSPBC25H2.07
TAS
SceS000004873
GO:0016282 eukaryotic 43S preinitiation complex C
ISS
PfaPF11_0447
GO:0003674 molecular_function F
ND
MmuMGI:1913485
GO:0003725 double-stranded RNA binding F
IDA
SceS000004873
ISS
SpoSPBC25H2.07
GO:0003743 translation initiation factor activity F
ISS
AthAt5g35680
At2g04520
SpoSPBC25H2.07
TAS
SceS000004873
GO:0008135 translation factor activity, nucleic acid
binding		 F
TAS
HsaEIF1AX
GO:0033592 RNA strand annealing activity F
IDA
SpoSPBC25H2.07
GO:0006413 translational initiation P
ISS
AthAt5g35680
At2g04520
SpoSPBC25H2.07
TAS
HsaEIF1AX
SceS000004873
GO:0008150 biological_process P
ND
MmuMGI:1913485
GO:0045948 positive regulation of translational
initiation		 P
ISS
SpoSPBC25H2.07

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_542

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga5405 ENSANGP00000016723
Ashbya gossypii (Ago) ago2777 AER275C
Arabidopsis thaliana (Ath) ath7859 At2g04520.1
Arabidopsis thaliana (Ath) ath25342 At5g35680.1
Arabidopsis thaliana (Ath) ath25343 At5g35680.2
Caenorhabditis elegans (Cel) cel11231 H06H21.3
(CE17962;
WBGene00019162)
Candida glabrata (Cgl) cgl2167 CAGL0H02409g
Dictyostelium discoideum (Ddi) ddi5116 DDB0204504
Debaryomyces hansenii (Dha) dha4710 DEHA0F07348g
Drosophila melanogaster (Dme) dme13202 CG8053-PA
(FBgn0026250)
Drosophila melanogaster (Dme) dme13203 CG8053-PB
(FBgn0026250)
Danio rerio (Dre) dre18888 ENSDARP00000014366
Danio rerio (Dre) dre16291 ENSDARP00000047005
Danio rerio (Dre) dre18895 ENSDARP00000048228
Encephalitozoon cuniculi (Ecu) ecu833 19074195
Takifugu rubripes (Fru) fru15922 SINFRUP00000127146
Gallus gallus (Gga) gga2350 ENSGALP00000026418
(RCJMB04_27j6)		 Q5ZIE2
Homo sapiens (Hsa) hsa399 ENSP00000288660
Homo sapiens (Hsa) hsa32536 ENSP00000312337
Homo sapiens (Hsa) hsa33815 ENSP00000354722
(EIF1AY)		 O14602
Kluyveromyces lactis (Kla) kla3457 KLLA0E11253g
Mus musculus (Mmu) mmu30148 ENSMUSP00000072812
Mus musculus (Mmu) mmu30714 ENSMUSP00000073122
Mus musculus (Mmu) mmu30814 ENSMUSP00000073741
Mus musculus (Mmu) mmu29803 ENSMUSP00000075073
Mus musculus (Mmu) mmu31516 ENSMUSP00000075575
Mus musculus (Mmu) mmu30703 ENSMUSP00000076409
Mus musculus (Mmu) mmu30784 ENSMUSP00000076742
Mus musculus (Mmu) mmu12675 ENSMUSP00000077223
(MGI:95298)		 Q60872
Mus musculus (Mmu) mmu6054 ENSMUSP00000078525
Mus musculus (Mmu) mmu30712 ENSMUSP00000078563
Mus musculus (Mmu) mmu31517 ENSMUSP00000079449
Mus musculus (Mmu) mmu30261 ENSMUSP00000080338
Neurospora crassa (Ncr) ncr7239 NCU07437.2
Oryza sativa (Osa) osa1588 1929.m00182
Oryza sativa (Osa) osa3519 2036.m00104
Oryza sativa (Osa) osa46159 5519.m00189
Oryza sativa (Osa) osa78655 7384.m00155
Plasmodium falciparum (Pfa) pfa894 PF11_0447
Rattus norvegicus (Rno) rno31373 ENSRNOP00000008509
(RGD:1560198)		 B5DF60
Rattus norvegicus (Rno) rno14124 ENSRNOP00000046345
(RGD:1306331)		 Q6VV72
Saccharomyces cerevisiae (Sce) sce5032 YMR260C
(S000004873)
Schizosaccharomyces pombe (Spo) spo1195 SPBC25H2.07 P55877
Yarrowia lipolytica (Yli) yli6234 YALI0F21153g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt2g04520
At5g35680
GO:0005634 nucleus C
IDA
SpoSPBC25H2.07
GO:0005829 cytosol C
IDA
SpoSPBC25H2.07
ISS
DmeFBgn0026250
NAS
DmeFBgn0026250
GO:0005840 ribosome C
ISS
SpoSPBC25H2.07
TAS
SceS000004873
GO:0016282 eukaryotic 43S preinitiation complex C
ISS
DmeFBgn0026250
PfaPF11_0447
GO:0003725 double-stranded RNA binding F
IDA
SceS000004873
ISS
SpoSPBC25H2.07
GO:0003743 translation initiation factor activity F
ISS
AthAt5g35680
At2g04520
DmeFBgn0026250
SpoSPBC25H2.07
TAS
SceS000004873
GO:0033592 RNA strand annealing activity F
IDA
SpoSPBC25H2.07
GO:0000003 reproduction P
IMP
CelWBGene00019162
GO:0000022 mitotic spindle elongation P
IMP
DmeFBgn0026250
GO:0006412 translation P
ISS
DmeFBgn0026250
GO:0006413 translational initiation P
ISS
AthAt5g35680
At2g04520
DmeFBgn0026250
SpoSPBC25H2.07
NAS
DmeFBgn0026250
TAS
SceS000004873
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00019162
GO:0006911 phagocytosis, engulfment P
IMP
DmeFBgn0026250
GO:0007052 mitotic spindle organization P
IMP
DmeFBgn0026250
GO:0007224 smoothened signaling pathway P
IGI
DmeFBgn0026250
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00019162
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00019162
GO:0040011 locomotion P
IMP
CelWBGene00019162
GO:0040018 positive regulation of multicellular organism
growth		 P
IMP
CelWBGene00019162
GO:0045948 positive regulation of translational
initiation		 P
ISS
SpoSPBC25H2.07

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC25H2.07
(P55877)		 YMR260C
(S000004873)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPBC25H2.07
GO:0005829 cytosol C
IDA
SpoSPBC25H2.07
GO:0005840 ribosome C
ISS
SpoSPBC25H2.07
TAS
SceS000004873
GO:0003725 double-stranded RNA binding F
IDA
SceS000004873
ISS
SpoSPBC25H2.07
GO:0003743 translation initiation factor activity F
ISS
SpoSPBC25H2.07
TAS
SceS000004873
GO:0033592 RNA strand annealing activity F
IDA
SpoSPBC25H2.07
GO:0006413 translational initiation P
ISS
SpoSPBC25H2.07
TAS
SceS000004873
GO:0045948 positive regulation of translational
initiation		 P
ISS
SpoSPBC25H2.07

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GO info in one table:

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