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Search term: YMR272C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SCS7
SGD link S000004885
Alternative ID YMR272C
Description Sphingolipid alpha-hydroxylase, functions in the alpha-hydroxylation of sphingolipid-associated very long chain fatty acids, has both cytochrome b5-like and hydroxylase/desaturase domains, not essential for growth
Synonyms YMR272C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

HomoloGene results:

HomoloGene cluster Phylogenetic pattern
56284

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) FA2H GI:205360949
Pan troglodytes (Ptr) FA2H GI:114663669
Canis familiaris (Cfa) FA2H GI:73957393
Mus musculus (Mmu) Fa2h
(MGI:2443327)		 GI:30017399 Q5MPP0
Rattus norvegicus (Rno) Fa2h GI:109508113
Gallus gallus (Gga) FA2H GI:118096202
Caenorhabditis elegans (Cel) C25A1.5
(CE08370;
WBGene00007707)		 GI:17505701 Q9XVS0
Schizosaccharomyces pombe (Spo) SPAC19G12.08 GI:19115335 O13846
Saccharomyces cerevisiae (Sce) SCS7
(S000004885)		 GI:6323928 Q03529
Kluyveromyces lactis (Kla) KLLA0D01639g GI:50306337
Eremothecium gossypii (Ego) AGOS_AAL183W GI:45184641
Magnaporthe grisea (Mgr) MGG_03920 GI:39943818
Neurospora crassa (Ncr) NCU03492.1 GI:32404274
Arabidopsis thaliana (Ath) FAH1 GI:15226828
Arabidopsis thaliana (Ath) FAH2 GI:15233426
Oryza sativa (Osa) Os03g0780800 GI:115455705
Oryza sativa (Osa) Os12g0628400 GI:115489684


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
AthFAH1
FAH2
SceS000004885
SpoSPAC19G12.08
ISS
SpoSPAC19G12.08
GO:0005789 endoplasmic reticulum membrane C
IC
SpoSPAC19G12.08
GO:0016020 membrane C
ISS
SceS000004885
GO:0000170 sphingosine hydroxylase activity F
ISS
SpoSPAC19G12.08
GO:0003824 catalytic activity F
ISS
AthFAH1
FAH2
GO:0004497 monooxygenase activity F
IDA
AthFAH1
GO:0046424 ferulate 5-hydroxylase activity F
IMP
AthFAH1
GO:0080132 fatty acid alpha-hydroxylase activity F
IGI
AthFAH2
FAH1
IMP
SceS000004885
GO:0000038 very long-chain fatty acid metabolic
process		 P
IDA
AthFAH1
IGI
AthFAH1
GO:0002119 nematode larval development P
IMP
CelWBGene00007707
GO:0006674 inositol phosphorylceramide metabolic
process		 P
IGI
SceS000004885
IMP
SceS000004885
GO:0006675 mannosyl-inositol phosphorylceramide metabolic
process		 P
IMP
SpoSPAC19G12.08
GO:0009699 phenylpropanoid biosynthetic process P
TAS
AthFAH1
GO:0009809 lignin biosynthetic process P
IMP
AthFAH1
TAS
AthFAH1
GO:0010224 response to UV-B P
IMP
AthFAH1
GO:0040007 growth P
IMP
CelWBGene00007707
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00007707
GO:0040018 positive regulation of multicellular organism
growth		 P
IMP
CelWBGene00007707
GO:0043069 negative regulation of programmed cell
death		 P
IGI
AthFAH1
FAH2

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_3058

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga8333 ENSANGP00000014963
Anopheles gambiae (Aga) aga8335 ENSANGP00000026166
Anopheles gambiae (Aga) aga8334 ENSANGP00000027567
Ashbya gossypii (Ago) ago4 AAL183W
Arabidopsis thaliana (Ath) ath10527 At2g34770.1
Arabidopsis thaliana (Ath) ath19992 At4g20870.1
Caenorhabditis elegans (Cel) cel2626 C25A1.5
(CE08370;
WBGene00007707)
Candida glabrata (Cgl) cgl1375 CAGL0F03399g
Cryptococcus neoformans (Cne) cne3485 176.m02209
Dictyostelium discoideum (Ddi) ddi4087 DDB0190661
Debaryomyces hansenii (Dha) dha4741 DEHA0F08118g
Drosophila melanogaster (Dme) dme3642 CG30502-PA
(FBgn0050502)
Danio rerio (Dre) dre28761 ENSDARP00000047813
Takifugu rubripes (Fru) fru3236 SINFRUP00000159194
Gallus gallus (Gga) gga4488 ENSGALP00000004373
(FA2H)
Homo sapiens (Hsa) hsa12510 ENSP00000219368
(FA2H)		 Q7L5A8
Kluyveromyces lactis (Kla) kla2141 KLLA0D01639g
Mus musculus (Mmu) mmu26713 ENSMUSP00000043597
(MGI:2443327)		 Q5MPP0-1
Neurospora crassa (Ncr) ncr3384 NCU03492.2
Oryza sativa (Osa) osa149 748.m00180
Rattus norvegicus (Rno) rno15027 ENSRNOP00000025625
(RGD:1310347)		 Q2LAM0
Saccharomyces cerevisiae (Sce) sce5044 YMR272C
(S000004885)
Schizosaccharomyces pombe (Spo) spo1758 SPAC19G12.08 O13846
Yarrowia lipolytica (Yli) yli5878 YALI0F12749g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
AthAt4g20870
SceS000004885
SpoSPAC19G12.08
ISS
SpoSPAC19G12.08
GO:0005789 endoplasmic reticulum membrane C
IC
SpoSPAC19G12.08
GO:0016020 membrane C
ISS
SceS000004885
GO:0000170 sphingosine hydroxylase activity F
ISS
SpoSPAC19G12.08
GO:0003824 catalytic activity F
ISS
AthAt2g34770
At4g20870
GO:0080132 fatty acid alpha-hydroxylase activity F
IGI
AthAt2g34770
At4g20870
IMP
SceS000004885
GO:0000038 very long-chain fatty acid metabolic
process		 P
IDA
AthAt2g34770
IGI
AthAt2g34770
GO:0002119 nematode larval development P
IMP
CelWBGene00007707
GO:0006674 inositol phosphorylceramide metabolic
process		 P
IGI
SceS000004885
IMP
SceS000004885
GO:0006675 mannosyl-inositol phosphorylceramide metabolic
process		 P
IMP
SpoSPAC19G12.08
GO:0040007 growth P
IMP
CelWBGene00007707
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00007707
GO:0040018 positive regulation of multicellular organism
growth		 P
IMP
CelWBGene00007707
GO:0043069 negative regulation of programmed cell
death		 P
IGI
AthAt2g34770
At4g20870

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC19G12.08
(O13846)		 YMR272C
(S000004885)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
SceS000004885
SpoSPAC19G12.08
ISS
SpoSPAC19G12.08
GO:0005789 endoplasmic reticulum membrane C
IC
SpoSPAC19G12.08
GO:0016020 membrane C
ISS
SceS000004885
GO:0000170 sphingosine hydroxylase activity F
ISS
SpoSPAC19G12.08
GO:0080132 fatty acid alpha-hydroxylase activity F
IMP
SceS000004885
GO:0006674 inositol phosphorylceramide metabolic
process		 P
IGI
SceS000004885
IMP
SceS000004885
GO:0006675 mannosyl-inositol phosphorylceramide metabolic
process		 P
IMP
SpoSPAC19G12.08

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GO info in one table:

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