Search term: YMR284W

Gene summary:

KOG results:

KOG name	Phylogenetic pattern (and link to KOGs with this pattern)
KOG2327	ACDHYP-

KOGs classification	KOGs description
INFORMATION STORAGE AND PROCESSING	DNA-binding subunit of a DNA-dependent protein kinase (Ku70 autoantigen)

Species	KOG link	NCBI link	UniProt link
Arabidopsis thaliana (Ath)	At1g16970	GI:15219967
Caenorhabditis elegans (Cel)	CE28984 (WBGene00000519)	GI:17555930
Drosophila melanogaster (Dme)	7299442 (FBgn0011774)	GI:17985997
Homo sapiens (Hsa)	Hs17437153_2	GI:17437153
Homo sapiens (Hsa)	Hs22050378	GI:22050378
Homo sapiens (Hsa)	Hs22056613	GI:22056613
Homo sapiens (Hsa)	Hs4503841 (XRCC6)	GI:4503841	P12956
Saccharomyces cerevisiae (Sce)	YMR284w (S000004897)	GI:6323940	P32807
Schizosaccharomyces pombe (Spo)	SPCC126.02c	GI:19075945	O94395

GO terms for KOG results:

GO ID	GO term	GO aspect	Evidence codes and associations
GO:0000781	chromosome, telomeric region	C	IDA Spo SPCC126.02c
GO:0000783	nuclear telomere cap complex	C	TAS Hsa XRCC6
GO:0000790	nuclear chromatin	C	TAS Sce S000004897
GO:0005624	membrane fraction	C	TAS Hsa XRCC6
GO:0005634	nucleus	C	IDA Spo SPCC126.02c NAS Dme FBgn0011774
GO:0005635	nuclear envelope	C	IDA Sce S000004897
GO:0005654	nucleoplasm	C	EXP Hsa XRCC6
GO:0005667	transcription factor complex	C	IDA Hsa XRCC6
GO:0005724	nuclear telomeric heterochromatin	C	TAS Sce S000004897
GO:0043564	Ku70:Ku80 complex	C	IDA Dme FBgn0011774 Hsa XRCC6 Sce S000004897
GO:0070419	nonhomologous end joining complex	C	IDA Hsa XRCC6
GO:0003677	DNA binding	F	IDA Dme FBgn0011774 FBgn0011774 ISS Dme FBgn0011774 NAS Dme FBgn0011774 Hsa XRCC6
GO:0003684	damaged DNA binding	F	TAS Sce S000004897
GO:0003690	double-stranded DNA binding	F	IDA Ath At1g16970 TAS Hsa XRCC6
GO:0003691	double-stranded telomeric DNA binding	F	IDA Hsa XRCC6
GO:0003723	RNA binding	F	IDA Sce S000004897
GO:0004003	ATP-dependent DNA helicase activity	F	ISS Spo SPCC126.02c NAS Dme FBgn0011774
GO:0004677	DNA-dependent protein kinase activity	F	NAS Dme FBgn0011774
GO:0005515	protein binding	F	IPI Ath At1g16970 Hsa XRCC6
GO:0008022	protein C-terminus binding	F	IPI Hsa XRCC6
GO:0010843	promoter binding	F	IDA Hsa XRCC6
GO:0016563	transcription activator activity	F	IMP Hsa XRCC6
GO:0042162	telomeric DNA binding	F	IDA Spo SPCC126.02c RCA Sce S000004897
GO:0043565	sequence-specific DNA binding	F	RCA Sce S000004897
GO:0046982	protein heterodimerization activity	F	IDA Dme FBgn0011774 IPI Spo SPCC126.02c
GO:0051575	5'-deoxyribose-5-phosphate lyase activity	F	IMP Hsa XRCC6
GO:0000084	S phase of mitotic cell cycle	P	IMP Spo SPCC126.02c
GO:0000723	telomere maintenance	P	IMP Dme FBgn0011774 Sce S000004897 Spo SPCC126.02c TAS Ath At1g16970 Hsa XRCC6
GO:0000724	double-strand break repair via homologous recombination	P	IMP Sce S000004897
GO:0000727	double-strand break repair via break-induced replication	P	IGI Sce S000004897 IMP Sce S000004897
GO:0006266	DNA ligation	P	TAS Hsa XRCC6
GO:0006281	DNA repair	P	TAS Ath At1g16970
GO:0006303	double-strand break repair via nonhomologous end joining	P	IDA Sce S000004897 IMP Hsa XRCC6 Spo SPCC126.02c TAS Hsa XRCC6
GO:0006333	chromatin assembly or disassembly	P	IDA Sce S000004897
GO:0006342	chromatin silencing	P	IDA Sce S000004897 IMP Sce S000004897
GO:0006950	response to stress	P	IMP Cel WBGene00000519
GO:0008340	determination of adult lifespan	P	IMP Cel WBGene00000519
GO:0009408	response to heat	P	IEP Ath At1g16970
GO:0010552	positive regulation of gene-specific transcription from RNA polymerase II promoter	P	IMP Hsa XRCC6
GO:0019047	provirus integration	P	EXP Hsa XRCC6
GO:0019059	initiation of viral infection	P	EXP Hsa XRCC6
GO:0030466	chromatin silencing at silent mating-type cassette	P	IGI Sce S000004897 IMP Sce S000004897
GO:0045893	positive regulation of transcription, DNA-dependent	P	IDA Hsa XRCC6

HomoloGene results:

HomoloGene cluster	Phylogenetic pattern
37483

Species	Gene ID	NCBI link	UniProt link
Homo sapiens (Hsa)	XRCC6	GI:4503841	P12956
Pan troglodytes (Ptr)	XRCC6	GI:114686702
Canis familiaris (Cfa)	XRCC6	GI:57092715
Mus musculus (Mmu)	Xrcc6 (MGI:95606)	GI:149266761	P23475
Rattus norvegicus (Rno)	Xrcc6 (RGD:2643)	GI:21717799	36380
Gallus gallus (Gga)	XRCC6	GI:45382537
Drosophila melanogaster (Dme)	Irbp (FBgn0011774)	GI:17985997
Anopheles gambiae (Aga)	AgaP_AGAP002690	GI:158290648
Caenorhabditis elegans (Cel)	cku-70 (CE28984; WBGene00000519)	GI:17555930
Schizosaccharomyces pombe (Spo)	pku70 (SPCC126.02c)	GI:19075945	O94395
Saccharomyces cerevisiae (Sce)	YKU70 (S000004897)	GI:6323940	P32807
Kluyveromyces lactis (Kla)	KLLA0C06226g	GI:50305035
Magnaporthe grisea (Mgr)	MGG_01512	GI:39951739
Neurospora crassa (Ncr)	NCU08290.1	GI:32417036
Arabidopsis thaliana (Ath)	KU70	GI:18394425
Oryza sativa (Osa)	Os07g0184900	GI:115470925

GO terms for Homologene results:

GO ID	GO term	GO aspect	Evidence codes and associations
GO:0000781	chromosome, telomeric region	C	IDA Spo SPCC126.02c
GO:0000783	nuclear telomere cap complex	C	TAS Hsa XRCC6
GO:0000790	nuclear chromatin	C	TAS Sce S000004897
GO:0005624	membrane fraction	C	TAS Hsa XRCC6
GO:0005634	nucleus	C	IDA Mmu MGI:95606 Spo SPCC126.02c ISO Mmu MGI:95606 NAS Dme FBgn0011774
GO:0005635	nuclear envelope	C	IDA Sce S000004897
GO:0005654	nucleoplasm	C	EXP Hsa XRCC6
GO:0005667	transcription factor complex	C	IDA Hsa XRCC6
GO:0005724	nuclear telomeric heterochromatin	C	TAS Sce S000004897
GO:0005730	nucleolus	C	ISO Mmu MGI:95606
GO:0005737	cytoplasm	C	IDA Mmu MGI:95606 ISO Mmu MGI:95606
GO:0043234	protein complex	C	ISO Mmu MGI:95606
GO:0043564	Ku70:Ku80 complex	C	IDA Dme FBgn0011774 Hsa XRCC6 Sce S000004897
GO:0070419	nonhomologous end joining complex	C	IDA Hsa XRCC6
GO:0003677	DNA binding	F	IDA Dme FBgn0011774 FBgn0011774 ISS Dme FBgn0011774 NAS Dme FBgn0011774 Hsa XRCC6
GO:0003684	damaged DNA binding	F	TAS Sce S000004897
GO:0003690	double-stranded DNA binding	F	IDA Ath KU70 ISO Mmu MGI:95606 TAS Hsa XRCC6
GO:0003691	double-stranded telomeric DNA binding	F	IDA Hsa XRCC6
GO:0003723	RNA binding	F	IDA Sce S000004897
GO:0004003	ATP-dependent DNA helicase activity	F	ISS Spo SPCC126.02c NAS Dme FBgn0011774
GO:0004677	DNA-dependent protein kinase activity	F	NAS Dme FBgn0011774
GO:0005515	protein binding	F	IPI Ath KU70 Hsa XRCC6
GO:0008022	protein C-terminus binding	F	IPI Hsa XRCC6
GO:0010843	promoter binding	F	IDA Hsa XRCC6
GO:0016563	transcription activator activity	F	IMP Hsa XRCC6
GO:0042162	telomeric DNA binding	F	IDA Spo SPCC126.02c RCA Sce S000004897
GO:0043565	sequence-specific DNA binding	F	RCA Sce S000004897
GO:0046982	protein heterodimerization activity	F	IDA Dme FBgn0011774 IPI Spo SPCC126.02c
GO:0051575	5'-deoxyribose-5-phosphate lyase activity	F	IMP Hsa XRCC6
GO:0000084	S phase of mitotic cell cycle	P	IMP Spo SPCC126.02c
GO:0000723	telomere maintenance	P	IMP Dme FBgn0011774 Sce S000004897 Spo SPCC126.02c TAS Ath KU70 Hsa XRCC6
GO:0000724	double-strand break repair via homologous recombination	P	IMP Sce S000004897
GO:0000727	double-strand break repair via break-induced replication	P	IGI Sce S000004897 IMP Sce S000004897
GO:0006266	DNA ligation	P	TAS Hsa XRCC6
GO:0006281	DNA repair	P	TAS Ath KU70
GO:0006302	double-strand break repair	P	IMP Mmu MGI:95606
GO:0006303	double-strand break repair via nonhomologous end joining	P	IDA Sce S000004897 IMP Hsa XRCC6 Mmu MGI:95606 Spo SPCC126.02c TAS Hsa XRCC6
GO:0006333	chromatin assembly or disassembly	P	IDA Sce S000004897
GO:0006342	chromatin silencing	P	IDA Sce S000004897 IMP Sce S000004897
GO:0006950	response to stress	P	IMP Cel WBGene00000519
GO:0006974	response to DNA damage stimulus	P	IMP Mmu MGI:95606
GO:0008340	determination of adult lifespan	P	IMP Cel WBGene00000519
GO:0009408	response to heat	P	IEP Ath KU70
GO:0010212	response to ionizing radiation	P	IMP Mmu MGI:95606
GO:0010552	positive regulation of gene-specific transcription from RNA polymerase II promoter	P	IMP Hsa XRCC6
GO:0019047	provirus integration	P	EXP Hsa XRCC6
GO:0019059	initiation of viral infection	P	EXP Hsa XRCC6
GO:0030466	chromatin silencing at silent mating-type cassette	P	IGI Sce S000004897 IMP Sce S000004897
GO:0033151	V(D)J recombination	P	IMP Mmu MGI:95606
GO:0045893	positive regulation of transcription, DNA-dependent	P	IDA Hsa XRCC6
GO:0050769	positive regulation of neurogenesis	P	IMP Mmu MGI:95606
GO:0071475	cellular hyperosmotic salinity response	P	ISO Mmu MGI:95606
GO:0071481	cellular response to X-ray	P	ISO Mmu MGI:95606