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Search term: YMR300C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ADE4
SGD link S000004915
Alternative ID YMR300C
Description Phosphoribosylpyrophosphate amidotransferase (PRPPAT; amidophosphoribosyltransferase), catalyzes first step of the 'de novo' purine nucleotide biosynthetic pathway
Synonyms YMR300C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0572 ACDHYP-

KOGs classification KOGs description
METABOLISM Glutamine phosphoribosylpyrophosphate amidotransferase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g16570 GI:15227244
Arabidopsis thaliana (Ath) At4g34740 GI:15236185
Arabidopsis thaliana (Ath) At4g38880 GI:15234861
Caenorhabditis elegans (Cel) CE01074
(WBGene00011407)		 GI:17554892 Q22134
Drosophila melanogaster (Dme) 7295319 GI:7295319
Drosophila melanogaster (Dme) 7298959 GI:17737835
Homo sapiens (Hsa) Hs19923227 GI:19923227
Saccharomyces cerevisiae (Sce) YMR300c
(S000004915)		 GI:6323958 P04046
Schizosaccharomyces pombe (Spo) SPAC4D7.08c GI:19115873 P41390
Arabidopsis thaliana (Ath) At2g16570 GI:15227244
Arabidopsis thaliana (Ath) At4g34740 GI:15236185
Arabidopsis thaliana (Ath) At4g38880 GI:15234861
Caenorhabditis elegans (Cel) CE01074
(WBGene00011407)		 GI:17554892 Q22134
Drosophila melanogaster (Dme) 7295319 GI:7295319
Drosophila melanogaster (Dme) 7298959 GI:17737835
Homo sapiens (Hsa) Hs19923227 GI:19923227
Saccharomyces cerevisiae (Sce) YMR300c
(S000004915)		 GI:6323958 P04046
Schizosaccharomyces pombe (Spo) SPAC4D7.08c GI:19115873 P41390


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005618 cell wall C
IDA
AthAt2g16570
GO:0005737 cytoplasm C
IDA
SceS000004915
SpoSPAC4D7.08c
ISS
SpoSPAC4D7.08c
GO:0009507 chloroplast C
IDA
AthAt4g34740
GO:0009532 plastid stroma C
IDA
AthAt4g34740
GO:0004044 amidophosphoribosyltransferase
activity		 F
IDA
SceS000004915
IMP
AthAt4g34740
SceS000004915
ISS
AthAt4g34740
At4g38880
At2g16570
TAS
AthAt4g34740
SpoSPAC4D7.08c
GO:0002119 nematode larval development P
IMP
CelWBGene00011407
GO:0006164 purine nucleotide biosynthetic
process		 P
IMP
AthAt4g34740
TAS
AthAt4g34740
SpoSPAC4D7.08c
GO:0006189 'de novo' IMP biosynthetic process P
IMP
SceS000004915
ISS
SpoSPAC4D7.08c
GO:0006519 cellular amino acid and derivative metabolic
process		 P
RCA
SceS000004915
GO:0006807 nitrogen compound metabolic process P
RCA
SceS000004915
GO:0008152 metabolic process P
ISS
AthAt2g16570
GO:0009113 purine base biosynthetic process P
IC
SpoSPAC4D7.08c
ISS
AthAt4g34740
At4g38880
At2g16570
GO:0009965 leaf morphogenesis P
IMP
AthAt4g34740
GO:0040007 growth P
IMP
CelWBGene00011407

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
68272

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) PPAT GI:29570798
Pan troglodytes (Ptr) PPAT GI:114594661
Canis familiaris (Cfa) PPAT GI:73975309
Mus musculus (Mmu) Ppat
(MGI:2387203)		 GI:94374856 Q3TKC5
Rattus norvegicus (Rno) Ppat
(RGD:620237)		 GI:62660274
Gallus gallus (Gga) PPAT GI:118090470
Drosophila melanogaster (Dme) Prat
(FBgn0004901)		 GI:28573187
Drosophila melanogaster (Dme) Prat2
(FBgn0041194)		 GI:24659598
Anopheles gambiae (Aga) AgaP_AGAP000179 GI:158289206
Caenorhabditis elegans (Cel) Amidophosphoribosyltransferase GI:17554892 Q22134
Schizosaccharomyces pombe (Spo) ade4
(SPAC4D7.08c)		 GI:19115873 P41390
Saccharomyces cerevisiae (Sce) ADE4
(S000004915)		 GI:6323958 P04046
Kluyveromyces lactis (Kla) KLLA0A10109g GI:50303009
Eremothecium gossypii (Ego) AGOS_AGL334W GI:45200763
Magnaporthe grisea (Mgr) MGG_04618 GI:145614540
Neurospora crassa (Ncr) NCU04216.1 GI:32405886
Arabidopsis thaliana (Ath) ATASE3 GI:15234861
Arabidopsis thaliana (Ath) ATASE1 GI:15227244
Arabidopsis thaliana (Ath) ATASE2 GI:15236185


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005618 cell wall C
IDA
AthATASE1
GO:0005625 soluble fraction C
ISO
MmuMGI:2387203
GO:0005737 cytoplasm C
IDA
SceS000004915
SpoSPAC4D7.08c
ISS
SpoSPAC4D7.08c
GO:0009507 chloroplast C
IDA
AthATASE2
GO:0009532 plastid stroma C
IDA
AthATASE2
GO:0004044 amidophosphoribosyltransferase
activity		 F
IDA
SceS000004915
IMP
AthATASE2
DmeFBgn0004901
SceS000004915
ISO
MmuMGI:2387203
ISS
AthATASE2
ATASE1
ATASE3
DmeFBgn0004901
FBgn0041194
TAS
AthATASE2
SpoSPAC4D7.08c
GO:0006164 purine nucleotide biosynthetic
process		 P
IMP
AthATASE2
TAS
AthATASE2
SpoSPAC4D7.08c
GO:0006189 'de novo' IMP biosynthetic process P
IMP
SceS000004915
ISS
DmeFBgn0041194
SpoSPAC4D7.08c
NAS
DmeFBgn0004901
GO:0006519 cellular amino acid and derivative metabolic
process		 P
RCA
SceS000004915
GO:0006807 nitrogen compound metabolic process P
RCA
SceS000004915
GO:0008152 metabolic process P
ISS
AthATASE1
GO:0008340 determination of adult lifespan P
IMP
DmeFBgn0004901
GO:0009113 purine base biosynthetic process P
IC
SpoSPAC4D7.08c
ISS
AthATASE2
ATASE3
ATASE1
DmeFBgn0004901
GO:0009168 purine ribonucleoside monophosphate biosynthetic
process		 P
EXP
HsaPPAT
GO:0009965 leaf morphogenesis P
IMP
AthATASE2
GO:0040016 embryonic cleavage P
IMP
DmeFBgn0004901
GO:0048477 oogenesis P
IMP
DmeFBgn0004901
GO:0051289 protein homotetramerization P
ISO
MmuMGI:2387203

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1009

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga14759 ENSANGP00000019430
Anopheles gambiae (Aga) aga14760 ENSANGP00000026283
Ashbya gossypii (Ago) ago3978 AGL334W
Arabidopsis thaliana (Ath) ath8494 At2g16570.1
Arabidopsis thaliana (Ath) ath21620 At4g34740.1
Arabidopsis thaliana (Ath) ath22083 At4g38880.1
Caenorhabditis elegans (Cel) cel14452 T04A8.5
(CE01074;
WBGene00011407)
Candida glabrata (Cgl) cgl5254 CAGL0M13717g
Cryptococcus neoformans (Cne) cne5547 179.m00402
Dictyostelium discoideum (Ddi) ddi11932 DDB0230083
Debaryomyces hansenii (Dha) dha5648 DEHA0F28204g
Drosophila melanogaster (Dme) dme8284 CG10078-PA
(FBgn0041194)
Drosophila melanogaster (Dme) dme8283 CG10078-PB
(FBgn0041194)
Drosophila melanogaster (Dme) dme11432 CG2867-PA
(FBgn0004901)
Danio rerio (Dre) dre26753 ENSDARP00000020598
(si:dkeyp-117h8.5)		 Q5RG53
Escherichia coli (Eco) eco2241 16130247
Takifugu rubripes (Fru) fru26520 SINFRUP00000146117
Takifugu rubripes (Fru) fru26519 SINFRUP00000165871
Takifugu rubripes (Fru) fru26518 SINFRUP00000166233
Gallus gallus (Gga) gga18050 ENSGALP00000022273
(PPAT)		 A7UEA8
Homo sapiens (Hsa) hsa24121 ENSP00000264220
(PPAT)		 Q06203
Kluyveromyces lactis (Kla) kla439 KLLA0A10109g
Mus musculus (Mmu) mmu20256 ENSMUSP00000031158
(MGI:2387203)		 Q3UGA8
Neurospora crassa (Ncr) ncr4092 NCU04216.2
Oryza sativa (Osa) osa27711 4217.m00173
Oryza sativa (Osa) osa30729 4365.m00154
Oryza sativa (Osa) osa48924 5829.m00156
Rattus norvegicus (Rno) rno10270 ENSRNOP00000002905
(RGD:620237)		 P35433
Saccharomyces cerevisiae (Sce) sce5076 YMR300C
(S000004915)
Schizosaccharomyces pombe (Spo) spo1802 SPAC4D7.08c P41390
Yarrowia lipolytica (Yli) yli1377 YALI0B15304g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005618 cell wall C
IDA
AthAt2g16570
GO:0005625 soluble fraction C
ISO
MmuMGI:2387203
GO:0005737 cytoplasm C
IDA
SceS000004915
SpoSPAC4D7.08c
ISS
SpoSPAC4D7.08c
GO:0009507 chloroplast C
IDA
AthAt4g34740
GO:0009532 plastid stroma C
IDA
AthAt4g34740
GO:0004044 amidophosphoribosyltransferase
activity		 F
IDA
SceS000004915
IMP
AthAt4g34740
DmeFBgn0004901
SceS000004915
ISO
MmuMGI:2387203
ISS
AthAt4g34740
At4g38880
At2g16570
DmeFBgn0004901
FBgn0041194
TAS
AthAt4g34740
SpoSPAC4D7.08c
GO:0002119 nematode larval development P
IMP
CelWBGene00011407
GO:0006164 purine nucleotide biosynthetic
process		 P
IMP
AthAt4g34740
TAS
AthAt4g34740
SpoSPAC4D7.08c
GO:0006189 'de novo' IMP biosynthetic process P
IMP
SceS000004915
ISS
DmeFBgn0041194
SpoSPAC4D7.08c
NAS
DmeFBgn0004901
GO:0006519 cellular amino acid and derivative metabolic
process		 P
RCA
SceS000004915
GO:0006807 nitrogen compound metabolic process P
RCA
SceS000004915
GO:0008152 metabolic process P
ISS
AthAt2g16570
GO:0008340 determination of adult lifespan P
IMP
DmeFBgn0004901
GO:0009113 purine base biosynthetic process P
IC
SpoSPAC4D7.08c
ISS
AthAt4g34740
At4g38880
At2g16570
DmeFBgn0004901
GO:0009965 leaf morphogenesis P
IMP
AthAt4g34740
GO:0040007 growth P
IMP
CelWBGene00011407
GO:0040016 embryonic cleavage P
IMP
DmeFBgn0004901
GO:0048477 oogenesis P
IMP
DmeFBgn0004901
GO:0051289 protein homotetramerization P
ISO
MmuMGI:2387203

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC4D7.08c
(P41390)		 YMR300C
(S000004915)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000004915
SpoSPAC4D7.08c
ISS
SpoSPAC4D7.08c
GO:0004044 amidophosphoribosyltransferase
activity		 F
IDA
SceS000004915
IMP
SceS000004915
TAS
SpoSPAC4D7.08c
GO:0006164 purine nucleotide biosynthetic
process		 P
TAS
SpoSPAC4D7.08c
GO:0006189 'de novo' IMP biosynthetic process P
IMP
SceS000004915
ISS
SpoSPAC4D7.08c
GO:0006519 cellular amino acid and derivative metabolic
process		 P
RCA
SceS000004915
GO:0006807 nitrogen compound metabolic process P
RCA
SceS000004915
GO:0009113 purine base biosynthetic process P
IC
SpoSPAC4D7.08c

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Search for gene by ID or name:

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GO info in one table:

s.khadayate@ucl.ac.uk