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Search term: YMR308C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PSE1
SGD link S000004925
Alternative ID YMR308C
Description Karyopherin/importin that interacts with the nuclear pore complex; acts as the nuclear import receptor for specific proteins, including Pdr1p, Yap1p, Ste12p, and Aft1p
Synonyms YMR308C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2171 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALINGCELLULAR PROCESSES AND SIGNALING Karyopherin (importin) beta 3

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At4g27630_1 GI:15234211
Arabidopsis thaliana (Ath) At4g27640 GI:15234235
Arabidopsis thaliana (Ath) At5g19820 GI:15241189
Caenorhabditis elegans (Cel) CE26971
(WBGene00002077)		 GI:17506191 Q9N5V3
Drosophila melanogaster (Dme) 7296831
(Karybeta3)		 GI:17737759
Homo sapiens (Hsa) Hs14756038 GI:14756038
Homo sapiens (Hsa) Hs16161756 GI:16161756
Homo sapiens (Hsa) Hs18874099 GI:18874099
Homo sapiens (Hsa) Hs21361131 GI:14756381
Homo sapiens (Hsa) Hs22061011 GI:22061011
Homo sapiens (Hsa) HsM4504909 GI:4504909
Saccharomyces cerevisiae (Sce) YER110c
(S000000912)		 GI:6320956 P40069
Saccharomyces cerevisiae (Sce) YMR308c
(S000004925)		 GI:6323968 P32337
Schizosaccharomyces pombe (Spo) SPBC14F5.03c GI:19113521 O60100
Schizosaccharomyces pombe (Spo) SPCC1840.03 GI:19076002 O74476


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000228 nuclear chromosome C
RCA
SceS000000912
GO:0005618 cell wall C
IDA
AthAt5g19820
GO:0005634 nucleus C
IDA
SceS000004925
S000000912
SpoSPBC14F5.03c
SPCC1840.03
ISS
AthAt4g27640
GO:0005635 nuclear envelope C
IDA
SpoSPBC14F5.03c
SPCC1840.03
GO:0005643 nuclear pore C
IDA
SceS000000912
ISS
AthAt4g27640
DmeKarybeta3
TAS
SpoSPBC14F5.03c
SPCC1840.03
GO:0005737 cytoplasm C
IDA
SceS000000912
S000004925
SpoSPCC1840.03
ISS
AthAt4g27640
GO:0005792 microsome C
IDA
AthAt4g27630
GO:0005829 cytosol C
IDA
DmeKarybeta3
SpoSPBC14F5.03c
SPCC1840.03
GO:0005875 microtubule associated complex C
IDA
DmeKarybeta3
GO:0005886 plasma membrane C
TAS
AthAt4g27630
GO:0030089 phycobilisome C
ISS
AthAt5g19820
GO:0031965 nuclear membrane C
IDA
SpoSPBC14F5.03c
SPCC1840.03
GO:0044427 chromosomal part C
RCA
SceS000000912
GO:0044454 nuclear chromosome part C
RCA
SceS000000912
GO:0005525 GTP binding F
IDA
AthAt4g27630
NAS
SpoSPCC1840.03
GO:0008320 protein transmembrane transporter
activity		 F
ISS
DmeKarybeta3
GO:0008565 protein transporter activity F
IMP
SceS000000912
S000004925
IPI
SceS000000912
S000004925
ISS
AthAt4g27640
TAS
SpoSPBC14F5.03c
SPCC1840.03
GO:0010427 abscisic acid binding F
IDA
AthAt4g27630
GO:0016829 lyase activity F
ISS
AthAt5g19820
GO:0051020 GTPase binding F
IPI
AthAt4g27630
GO:0000003 reproduction P
IMP
CelWBGene00002077
GO:0000059 protein import into nucleus, docking P
ISS
AthAt4g27640
GO:0001703 gastrulation with mouth forming
first		 P
IMP
CelWBGene00002077
GO:0002119 nematode larval development P
IMP
CelWBGene00002077
GO:0006406 mRNA export from nucleus P
IGI
SceS000004925
GO:0006417 regulation of translation P
RCA
SceS000004925
S000000912
GO:0006605 protein targeting P
NAS
SpoSPBC14F5.03c
GO:0006606 protein import into nucleus P
IDA
SpoSPCC1840.03
IMP
SceS000000912
S000004925
ISS
DmeKarybeta3
GO:0006609 mRNA-binding (hnRNP) protein import into
nucleus		 P
RCA
SceS000004925
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00002077
GO:0006913 nucleocytoplasmic transport P
TAS
SpoSPBC14F5.03c
GO:0007346 regulation of mitotic cell cycle P
IMP
SpoSPCC1840.03
GO:0007369 gastrulation P
IMP
CelWBGene00002077
GO:0009737 response to abscisic acid stimulus P
IGI
AthAt4g27630
GO:0009790 embryo development P
IMP
CelWBGene00002077
GO:0009791 post-embryonic development P
IGI
AthAt4g27630
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00002077
GO:0009793 embryo development ending in seed
dormancy		 P
NAS
AthAt5g19820
GO:0010228 vegetative to reproductive phase transition of
meristem		 P
IGI
AthAt4g27630
GO:0018996 molting cycle, collagen and cuticulin-based
cuticle		 P
IMP
CelWBGene00002077
GO:0034613 cellular protein localization P
IGI
SpoSPCC1840.03
GO:0040007 growth P
IMP
CelWBGene00002077
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00002077

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
1710

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) IPO5 GI:24797086
Pan troglodytes (Ptr) IPO5 GI:114650444
Canis familiaris (Cfa) IPO5 GI:73989213
Mus musculus (Mmu) Ipo5
(MGI:1917822)		 GI:29789199 Q3TT04
Rattus norvegicus (Rno) Ipo5 GI:109502015
Gallus gallus (Gga) IPO5 GI:118084696
Drosophila melanogaster (Dme) Karybeta3 GI:17737759
Anopheles gambiae (Aga) AgaP_AGAP003769 GI:118780654
Caenorhabditis elegans (Cel) imb-3
(CE26971;
WBGene00002077)		 GI:17506191 Q9N5V3
Schizosaccharomyces pombe (Spo) pse1
(SPCC1840.03)		 GI:19076002 O74476
Saccharomyces cerevisiae (Sce) PSE1
(S000004925)		 GI:6323968 P32337
Kluyveromyces lactis (Kla) KLLA0C14157g GI:50305745
Eremothecium gossypii (Ego) AGOS_AGL349C GI:45200748
Magnaporthe grisea (Mgr) MGG_03537 GI:145616144
Neurospora crassa (Ncr) NCU02357.1 GI:32421379
Arabidopsis thaliana (Ath) emb2734 GI:15241189
Oryza sativa (Osa) Os07g0575100 GI:115472957
Plasmodium falciparum (Pfa) PFE1195w GI:124506397


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005618 cell wall C
IDA
Athemb2734
GO:0005634 nucleus C
IDA
SceS000004925
SpoSPCC1840.03
GO:0005635 nuclear envelope C
IDA
SpoSPCC1840.03
GO:0005643 nuclear pore C
ISS
DmeKarybeta3
NAS
PfaPFE1195w
TAS
HsaIPO5
SpoSPCC1840.03
GO:0005737 cytoplasm C
IDA
SceS000004925
SpoSPCC1840.03
GO:0005829 cytosol C
IDA
DmeKarybeta3
SpoSPCC1840.03
GO:0005875 microtubule associated complex C
IDA
DmeKarybeta3
GO:0030089 phycobilisome C
ISS
Athemb2734
GO:0031965 nuclear membrane C
IDA
SpoSPCC1840.03
GO:0005095 GTPase inhibitor activity F
TAS
HsaIPO5
GO:0005515 protein binding F
IPI
HsaIPO5
MmuMGI:1917822
GO:0005525 GTP binding F
NAS
SpoSPCC1840.03
GO:0008320 protein transmembrane transporter
activity		 F
ISS
DmeKarybeta3
GO:0008536 Ran GTPase binding F
TAS
HsaIPO5
GO:0008565 protein transporter activity F
IMP
SceS000004925
IPI
SceS000004925
TAS
SpoSPCC1840.03
GO:0016829 lyase activity F
ISS
Athemb2734
GO:0000003 reproduction P
IMP
CelWBGene00002077
GO:0001703 gastrulation with mouth forming
first		 P
IMP
CelWBGene00002077
GO:0002119 nematode larval development P
IMP
CelWBGene00002077
GO:0006406 mRNA export from nucleus P
IGI
SceS000004925
GO:0006417 regulation of translation P
RCA
SceS000004925
GO:0006606 protein import into nucleus P
IDA
SpoSPCC1840.03
IMP
SceS000004925
ISS
DmeKarybeta3
GO:0006607 NLS-bearing substrate import into
nucleus		 P
TAS
HsaIPO5
GO:0006609 mRNA-binding (hnRNP) protein import into
nucleus		 P
RCA
SceS000004925
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00002077
GO:0007346 regulation of mitotic cell cycle P
IMP
SpoSPCC1840.03
GO:0007369 gastrulation P
IMP
CelWBGene00002077
GO:0009790 embryo development P
IMP
CelWBGene00002077
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00002077
GO:0009793 embryo development ending in seed
dormancy		 P
NAS
Athemb2734
GO:0018996 molting cycle, collagen and cuticulin-based
cuticle		 P
IMP
CelWBGene00002077
GO:0034613 cellular protein localization P
IGI
SpoSPCC1840.03
GO:0040007 growth P
IMP
CelWBGene00002077
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00002077

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1093

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga6250 ENSANGP00000015236
Ashbya gossypii (Ago) ago3963 AGL349C
Arabidopsis thaliana (Ath) ath24255 At5g19820.1
Caenorhabditis elegans (Cel) cel4674 C53D5.6
(CE26971;
WBGene00002077)
Candida glabrata (Cgl) cgl5261 CAGL0M13871g
Cryptococcus neoformans (Cne) cne3146 167.m03482
Dictyostelium discoideum (Ddi) ddi10286 DDB0219662
Debaryomyces hansenii (Dha) dha1961 DEHA0C12012g
Drosophila melanogaster (Dme) dme10904 CG1059-PA
(FBgn0011341)
Danio rerio (Dre) dre26539 ENSDARP00000035787
Danio rerio (Dre) dre26540 ENSDARP00000036270
Danio rerio (Dre) dre26538 ENSDARP00000050636
Takifugu rubripes (Fru) fru9656 SINFRUP00000165332
Takifugu rubripes (Fru) fru9657 SINFRUP00000165644
Gallus gallus (Gga) gga2799 ENSGALP00000027237
Gallus gallus (Gga) gga2800 ENSGALP00000027238
(IPO5)
Gallus gallus (Gga) gga2798 ENSGALP00000027239
Homo sapiens (Hsa) hsa31005 ENSP00000259569
(RANBP6)		 O60518
Homo sapiens (Hsa) hsa8955 ENSP00000261574
(IPO5)		 O00410-3
Homo sapiens (Hsa) hsa8954 ENSP00000350219
(IPO5)		 O00410-1
Homo sapiens (Hsa) hsa31004 ENSP00000355322
Kluyveromyces lactis (Kla) kla1832 KLLA0C14157g
Mus musculus (Mmu) mmu8667 ENSMUSP00000032898
(MGI:1917822)		 Q8BKC5-1
Neurospora crassa (Ncr) ncr2290 NCU02357.2
Oryza sativa (Osa) osa4101 2086.m00250
Oryza sativa (Osa) osa18752 3216.m00155
Oryza sativa (Osa) osa20217 3401.m00172
Plasmodium falciparum (Pfa) pfa3689 PFE1195w
Rattus norvegicus (Rno) rno11876 ENSRNOP00000014859
(RGD:1308715)
Rattus norvegicus (Rno) rno3964 ENSRNOP00000032280
Saccharomyces cerevisiae (Sce) sce5087 YMR308C
(S000004925)
Schizosaccharomyces pombe (Spo) spo4975 SPCC1840.03 O74476
Yarrowia lipolytica (Yli) yli5957 YALI0F14575g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005618 cell wall C
IDA
AthAt5g19820
GO:0005634 nucleus C
IDA
SceS000004925
SpoSPCC1840.03
GO:0005635 nuclear envelope C
IDA
SpoSPCC1840.03
GO:0005643 nuclear pore C
NAS
PfaPFE1195w
TAS
SpoSPCC1840.03
GO:0005737 cytoplasm C
IDA
SceS000004925
SpoSPCC1840.03
GO:0005829 cytosol C
IDA
SpoSPCC1840.03
GO:0030089 phycobilisome C
ISS
AthAt5g19820
GO:0031965 nuclear membrane C
IDA
SpoSPCC1840.03
GO:0005515 protein binding F
IPI
MmuMGI:1917822
GO:0005525 GTP binding F
NAS
SpoSPCC1840.03
GO:0008565 protein transporter activity F
IMP
SceS000004925
IPI
SceS000004925
TAS
SpoSPCC1840.03
GO:0016829 lyase activity F
ISS
AthAt5g19820
GO:0000003 reproduction P
IMP
CelWBGene00002077
GO:0001703 gastrulation with mouth forming
first		 P
IMP
CelWBGene00002077
GO:0002119 nematode larval development P
IMP
CelWBGene00002077
GO:0006406 mRNA export from nucleus P
IGI
SceS000004925
GO:0006417 regulation of translation P
RCA
SceS000004925
GO:0006606 protein import into nucleus P
IDA
SpoSPCC1840.03
IMP
SceS000004925
GO:0006609 mRNA-binding (hnRNP) protein import into
nucleus		 P
RCA
SceS000004925
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00002077
GO:0007346 regulation of mitotic cell cycle P
IMP
SpoSPCC1840.03
GO:0007369 gastrulation P
IMP
CelWBGene00002077
GO:0009790 embryo development P
IMP
CelWBGene00002077
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00002077
GO:0009793 embryo development ending in seed
dormancy		 P
NAS
AthAt5g19820
GO:0018996 molting cycle, collagen and cuticulin-based
cuticle		 P
IMP
CelWBGene00002077
GO:0034613 cellular protein localization P
IGI
SpoSPCC1840.03
GO:0040007 growth P
IMP
CelWBGene00002077
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00002077

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC1840.03
(O74476)		 YMR308C
(S000004925)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000004925
SpoSPCC1840.03
GO:0005635 nuclear envelope C
IDA
SpoSPCC1840.03
GO:0005643 nuclear pore C
TAS
SpoSPCC1840.03
GO:0005737 cytoplasm C
IDA
SceS000004925
SpoSPCC1840.03
GO:0005829 cytosol C
IDA
SpoSPCC1840.03
GO:0031965 nuclear membrane C
IDA
SpoSPCC1840.03
GO:0005525 GTP binding F
NAS
SpoSPCC1840.03
GO:0008565 protein transporter activity F
IMP
SceS000004925
IPI
SceS000004925
TAS
SpoSPCC1840.03
GO:0006406 mRNA export from nucleus P
IGI
SceS000004925
GO:0006417 regulation of translation P
RCA
SceS000004925
GO:0006606 protein import into nucleus P
IDA
SpoSPCC1840.03
IMP
SceS000004925
GO:0006609 mRNA-binding (hnRNP) protein import into
nucleus		 P
RCA
SceS000004925
GO:0007346 regulation of mitotic cell cycle P
IMP
SpoSPCC1840.03
GO:0034613 cellular protein localization P
IGI
SpoSPCC1840.03

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