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Search term: YNL006W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name LST8
SGD link S000004951
Alternative ID YNL006W
Description Protein required for the transport of amino acid permease Gap1p from the Golgi to the cell surface; component of the TOR signaling pathway; associates with both Tor1p and Tor2p; contains a WD-repeat
Synonyms YNL006W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0315 ACDHYP-

KOGs classification KOGs description
POORLY CHARACTERIZED G-protein beta subunit-like protein (contains WD40 repeats)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g22040 GI:15227141
Arabidopsis thaliana (Ath) At3g18140 GI:15229590
Caenorhabditis elegans (Cel) CE08097
(WBGene00015697)		 GI:17505566 P91040
Drosophila melanogaster (Dme) 7291072 GI:7291072
Homo sapiens (Hsa) Hs21361908 GI:18088123
Homo sapiens (Hsa) HsM11641233 GI:11641233
Saccharomyces cerevisiae (Sce) YNL006w
(S000004951)		 GI:6324322 P41318
Schizosaccharomyces pombe (Spo) SPBC21B10.05c GI:19112474 O74184
Arabidopsis thaliana (Ath) At2g22040 GI:15227141
Arabidopsis thaliana (Ath) At3g18140 GI:15229590
Caenorhabditis elegans (Cel) CE08097
(WBGene00015697)		 GI:17505566 P91040
Drosophila melanogaster (Dme) 7291072 GI:7291072
Homo sapiens (Hsa) Hs21361908 GI:18088123
Homo sapiens (Hsa) HsM11641233 GI:11641233
Saccharomyces cerevisiae (Sce) YNL006w
(S000004951)		 GI:6324322 P41318
Schizosaccharomyces pombe (Spo) SPBC21B10.05c GI:19112474 O74184
Arabidopsis thaliana (Ath) At2g22040 GI:15227141
Arabidopsis thaliana (Ath) At3g18140 GI:15229590
Caenorhabditis elegans (Cel) CE08097
(WBGene00015697)		 GI:17505566 P91040
Drosophila melanogaster (Dme) 7291072 GI:7291072
Homo sapiens (Hsa) Hs21361908 GI:18088123
Homo sapiens (Hsa) HsM11641233 GI:11641233
Saccharomyces cerevisiae (Sce) YNL006w
(S000004951)		 GI:6324322 P41318
Schizosaccharomyces pombe (Spo) SPBC21B10.05c GI:19112474 O74184


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000139 Golgi membrane C
IDA
SceS000004951
GO:0000300 peripheral to membrane of membrane
fraction		 C
IDA
SceS000004951
GO:0005634 nucleus C
IDA
SpoSPBC21B10.05c
GO:0005829 cytosol C
IDA
SpoSPBC21B10.05c
GO:0010008 endosome membrane C
IDA
SceS000004951
GO:0031234 extrinsic to internal side of plasma
membrane		 C
IDA
SceS000004951
GO:0031931 TORC1 complex C
IDA
SpoSPBC21B10.05c
IPI
SceS000004951
GO:0031932 TORC2 complex C
IDA
SpoSPBC21B10.05c
IPI
SceS000004951
GO:0080008 CUL4 RING ubiquitin ligase complex C
ISS
AthAt3g18140
At2g22040
GO:0000166 nucleotide binding F
ISS
AthAt3g18140
At2g22040
GO:0005515 protein binding F
IPI
SceS000004951
SpoSPBC21B10.05c
GO:0030295 protein kinase activator activity F
IMP
SceS000004951
GO:0000226 microtubule cytoskeleton organization P
IMP
SpoSPBC21B10.05c
GO:0001558 regulation of cell growth P
IPI
SceS000004951
GO:0002119 nematode larval development P
IMP
CelWBGene00015697
GO:0006397 mRNA processing P
IMP
SpoSPBC21B10.05c
GO:0006810 transport P
IMP
SceS000004951
GO:0007047 cellular cell wall organization P
RCA
SceS000004951
GO:0007059 chromosome segregation P
IMP
SpoSPBC21B10.05c
GO:0007165 signal transduction P
IMP
SceS000004951
GO:0008150 biological_process P
ND
AthAt2g22040
At3g18140
GO:0019915 lipid storage P
IMP
CelWBGene00015697
GO:0030950 establishment or maintenance of actin cytoskeleton
polarity		 P
IMP
SceS000004951
GO:0031505 fungal-type cell wall organization P
IMP
SceS000004951
GO:0031929 TOR signaling cascade P
IC
SceS000004951
IMP
SceS000004951
TAS
SpoSPBC21B10.05c
GO:0031930 mitochondria-nucleus signaling
pathway		 P
IMP
SceS000004951
GO:0040007 growth P
IMP
CelWBGene00015697
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00015697
GO:0040018 positive regulation of multicellular organism
growth		 P
IMP
CelWBGene00015697

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
6833

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) MLST8 GI:84626578
Pan troglodytes (Ptr) MLST8 GI:114660495
Canis familiaris (Cfa) MLST8 GI:73959507
Mus musculus (Mmu) Mlst8
(MGI:1929514)		 GI:31542885 Q9DCJ1
Rattus norvegicus (Rno) Mlst8 GI:11693178
Gallus gallus (Gga) MLST8 GI:118097984
Drosophila melanogaster (Dme) CG3004
(FBgn0030142)		 GI:18858099
Anopheles gambiae (Aga) AgaP_AGAP001036 GI:118779379
Schizosaccharomyces pombe (Spo) pop3
(SPBC21B10.05c)		 GI:19112474 O74184
Saccharomyces cerevisiae (Sce) LST8
(S000004951)		 GI:6324322 P41318
Kluyveromyces lactis (Kla) KLLA0D04840g GI:50306603
Eremothecium gossypii (Ego) AGOS_AAL009C GI:45184815
Magnaporthe grisea (Mgr) MGG_07284 GI:145612659
Neurospora crassa (Ncr) NCU04281.1 GI:32406016
Arabidopsis thaliana (Ath) AT3G18140 GI:15229590
Oryza sativa (Osa) Os03g0681700 GI:115454613


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000139 Golgi membrane C
IDA
SceS000004951
GO:0000300 peripheral to membrane of membrane
fraction		 C
IDA
SceS000004951
GO:0005634 nucleus C
IDA
SpoSPBC21B10.05c
GO:0005737 cytoplasm C
ISO
MmuMGI:1929514
ISS
HsaMLST8
GO:0005829 cytosol C
EXP
HsaMLST8
IDA
SpoSPBC21B10.05c
ISO
MmuMGI:1929514
GO:0005834 heterotrimeric G-protein complex C
ISS
DmeFBgn0030142
GO:0010008 endosome membrane C
IDA
SceS000004951
GO:0031234 extrinsic to internal side of plasma
membrane		 C
IDA
SceS000004951
GO:0031931 TORC1 complex C
IDA
SpoSPBC21B10.05c
IPI
SceS000004951
ISO
MmuMGI:1929514
GO:0031932 TORC2 complex C
IDA
SpoSPBC21B10.05c
IPI
SceS000004951
ISO
MmuMGI:1929514
GO:0080008 CUL4 RING ubiquitin ligase complex C
ISS
AthAt3g18140
GO:0000166 nucleotide binding F
ISS
AthAt3g18140
GO:0003924 GTPase activity F
ISS
DmeFBgn0030142
GO:0005515 protein binding F
IPI
HsaMLST8
SceS000004951
SpoSPBC21B10.05c
GO:0030295 protein kinase activator activity F
IMP
SceS000004951
GO:0000226 microtubule cytoskeleton organization P
IMP
SpoSPBC21B10.05c
GO:0001558 regulation of cell growth P
IPI
SceS000004951
GO:0006397 mRNA processing P
IMP
SpoSPBC21B10.05c
GO:0006810 transport P
IMP
SceS000004951
GO:0007047 cellular cell wall organization P
RCA
SceS000004951
GO:0007059 chromosome segregation P
IMP
SpoSPBC21B10.05c
GO:0007165 signal transduction P
IMP
SceS000004951
GO:0008150 biological_process P
ND
AthAt3g18140
DmeFBgn0030142
GO:0030838 positive regulation of actin filament
polymerization		 P
IMP
MmuMGI:1929514
GO:0030950 establishment or maintenance of actin cytoskeleton
polarity		 P
IMP
SceS000004951
GO:0031505 fungal-type cell wall organization P
IMP
SceS000004951
GO:0031929 TOR signaling cascade P
IC
SceS000004951
IMP
SceS000004951
TAS
SpoSPBC21B10.05c
GO:0031930 mitochondria-nucleus signaling
pathway		 P
IMP
SceS000004951
GO:0032008 positive regulation of TOR signaling
cascade		 P
IMP
HsaMLST8
GO:0032314 regulation of Rac GTPase activity P
IMP
MmuMGI:1929514
GO:0032956 regulation of actin cytoskeleton
organization		 P
IMP
HsaMLST8
GO:0050731 positive regulation of peptidyl-tyrosine
phosphorylation		 P
IMP
MmuMGI:1929514

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_3116

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga15750 ENSANGP00000016015
Anopheles gambiae (Aga) aga15751 ENSANGP00000026987
Ashbya gossypii (Ago) ago178 AAL009C
Arabidopsis thaliana (Ath) ath14074 At3g18140.1
Caenorhabditis elegans (Cel) cel1782 C10H11.8
(CE08097;
WBGene00015697)
Candida glabrata (Cgl) cgl2223 CAGL0H03729g
Cryptococcus neoformans (Cne) cne1719 164.m02077
Dictyostelium discoideum (Ddi) ddi10862 DDB0184464
Debaryomyces hansenii (Dha) dha6223 DEHA0G11770g
Drosophila melanogaster (Dme) dme17161 CG3004-PA
(FBgn0030142)
Danio rerio (Dre) dre3367 ENSDARP00000019416
(zgc:55455)		 Q803V5
Takifugu rubripes (Fru) fru7749 SINFRUP00000141791
Gallus gallus (Gga) gga6601 ENSGALP00000009432
(MLST8)
Homo sapiens (Hsa) hsa11494 ENSP00000301724
(MLST8)
Kluyveromyces lactis (Kla) kla2274 KLLA0D04840g
Mus musculus (Mmu) mmu11086 ENSMUSP00000065004
(MGI:1929514)		 Q9DCJ1
Neurospora crassa (Ncr) ncr4157 NCU04281.2
Oryza sativa (Osa) osa66787 6833.m00138
Oryza sativa (Osa) osa310 751.m00121
Rattus norvegicus (Rno) rno4603 ENSRNOP00000014269
(RGD:69242)		 Q9Z2K5
Saccharomyces cerevisiae (Sce) sce5114 YNL006W
(S000004951)
Schizosaccharomyces pombe (Spo) spo2273 SPBC21B10.05c O74184
Yarrowia lipolytica (Yli) yli4421 YALI0E13530g