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Search term: YNL037C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name IDH1
SGD link S000004982
Alternative ID YNL037C
Description Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase, which catalyzes the oxidation of isocitrate to alpha-ketoglutarate in the TCA cycle
Synonyms YNL037C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0784 ACDHYP-

KOGs classification KOGs description
METABOLISM Isocitrate dehydrogenase, gamma subunit

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g32480 GI:15223219
Arabidopsis thaliana (Ath) At2g17130 GI:15227370
Arabidopsis thaliana (Ath) At4g35260 GI:15236932
Arabidopsis thaliana (Ath) At4g35650 GI:15237075
Caenorhabditis elegans (Cel) CE00970 GI:17553258
Caenorhabditis elegans (Cel) CE08620
(WBGene00007993)		 GI:17550882 Q93353
Caenorhabditis elegans (Cel) CE16887
(WBGene00016266)		 GI:17505779 Q95YD8
Drosophila melanogaster (Dme) 7300799 GI:7300799
Drosophila melanogaster (Dme) 7301367 GI:7301367
Drosophila melanogaster (Dme) 7302952 GI:20130045
Homo sapiens (Hsa) Hs5901982 GI:5901982
Homo sapiens (Hsa) Hs4758582
(IDH3G)		 GI:4758582 P51553
Saccharomyces cerevisiae (Sce) YNL037c
(S000004982)		 GI:6324291 P28834
Schizosaccharomyces pombe (Spo) SPAC11G7.03 GI:19115309 O13696
Arabidopsis thaliana (Ath) At1g32480 GI:15223219
Arabidopsis thaliana (Ath) At2g17130 GI:15227370
Arabidopsis thaliana (Ath) At4g35260 GI:15236932
Arabidopsis thaliana (Ath) At4g35650 GI:15237075
Caenorhabditis elegans (Cel) CE00970 GI:17553258
Caenorhabditis elegans (Cel) CE08620
(WBGene00007993)		 GI:17550882 Q93353
Caenorhabditis elegans (Cel) CE16887
(WBGene00016266)		 GI:17505779 Q95YD8
Drosophila melanogaster (Dme) 7300799 GI:7300799
Drosophila melanogaster (Dme) 7301367 GI:7301367
Drosophila melanogaster (Dme) 7302952 GI:20130045
Homo sapiens (Hsa) Hs5901982 GI:5901982
Homo sapiens (Hsa) Hs4758582
(IDH3G)		 GI:4758582 P51553
Saccharomyces cerevisiae (Sce) YNL037c
(S000004982)		 GI:6324291 P28834
Schizosaccharomyces pombe (Spo) SPAC11G7.03 GI:19115309 O13696


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
HsaIDH3G
GO:0005730 nucleolus C
IDA
HsaIDH3G
GO:0005737 cytoplasm C
IDA
SpoSPAC11G7.03
GO:0005739 mitochondrion C
IDA
AthAt4g35650
At2g17130
At4g35260
HsaIDH3G
SceS000004982
ISS
HsaIDH3G
GO:0005759 mitochondrial matrix C
IDA
SceS000004982
ISS
SpoSPAC11G7.03
GO:0005962 mitochondrial isocitrate dehydrogenase complex
(NAD+)		 C
IDA
SceS000004982
GO:0042645 mitochondrial nucleoid C
IDA
SceS000004982
GO:0004449 isocitrate dehydrogenase (NAD+)
activity		 F
IDA
SceS000004982
IGI
AthAt4g35650
IMP
SpoSPAC11G7.03
ISS
AthAt4g35650
At4g35260
At2g17130
HsaIDH3G
GO:0008270 zinc ion binding F
IDA
AthAt4g35260
GO:0016491 oxidoreductase activity F
ISS
AthAt1g32480
GO:0005975 carbohydrate metabolic process P
NAS
HsaIDH3G
GO:0006099 tricarboxylic acid cycle P
IMP
SpoSPAC11G7.03
TAS
AthAt4g35260
At4g35650
At2g17130
SceS000004982
GO:0006102 isocitrate metabolic process P
IGI
AthAt4g35650
IMP
AthAt2g17130
At4g35260
SpoSPAC11G7.03
ISS
HsaIDH3G
TAS
SceS000004982
GO:0006537 glutamate biosynthetic process P
IMP
SpoSPAC11G7.03
TAS
SceS000004982
GO:0008152 metabolic process P
ISS
AthAt4g35260
At2g17130
At1g32480
At4g35650
GO:0051186 cofactor metabolic process P
RCA
SceS000004982
GO:0055114 oxidation reduction P
RCA
SceS000004982

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
5035

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) IDH3B GI:28178821
Pan troglodytes (Ptr) IDH3B GI:114680553
Canis familiaris (Cfa) IDH3B GI:73991469
Mus musculus (Mmu) Idh3b
(MGI:2158650)		 GI:18700024 Q91VA7
Rattus norvegicus (Rno) Idh3B
(RGD:621881)		 GI:55926203
Gallus gallus (Gga) RCJMB04_9n20 GI:71897269
Drosophila melanogaster (Dme) CG6439
(FBgn0038922)		 GI:24648872
Anopheles gambiae (Aga) AgaP_AGAP007786 GI:158297500
Caenorhabditis elegans (Cel) C37E2.1
(CE08620;
WBGene00007993)		 GI:17550882 Q93353
Schizosaccharomyces pombe (Spo) glu3 GI:19115309
Saccharomyces cerevisiae (Sce) IDH1
(S000004982)		 GI:6324291 P28834
Kluyveromyces lactis (Kla) IDH1_KLULA GI:50310493
Eremothecium gossypii (Ego) AGOS_ADL223W GI:45187650
Magnaporthe grisea (Mgr) MGG_01995 GI:145604955
Neurospora crassa (Ncr) NCU00775.1 GI:32408949
Arabidopsis thaliana (Ath) IDH1 GI:15236932
Arabidopsis thaliana (Ath) IDH2 GI:15227370
Oryza sativa (Osa) Os02g0595500 GI:115447069
Oryza sativa (Osa) Os04g0479200 GI:115458986


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
AthIDH2
IDH1
MmuMGI:2158650
SceS000004982
ISS
DmeFBgn0038922
GO:0005759 mitochondrial matrix C
IDA
SceS000004982
GO:0005875 microtubule associated complex C
IDA
DmeFBgn0038922
GO:0005962 mitochondrial isocitrate dehydrogenase complex
(NAD+)		 C
IDA
SceS000004982
GO:0042645 mitochondrial nucleoid C
IDA
SceS000004982
GO:0004449 isocitrate dehydrogenase (NAD+)
activity		 F
IDA
SceS000004982
ISO
MmuMGI:2158650
ISS
AthIDH2
IDH1
DmeFBgn0038922
GO:0008270 zinc ion binding F
IDA
AthIDH1
GO:0009055 electron carrier activity F
TAS
HsaIDH3B
GO:0006099 tricarboxylic acid cycle P
ISO
MmuMGI:2158650
ISS
DmeFBgn0038922
TAS
AthIDH2
IDH1
SceS000004982
GO:0006102 isocitrate metabolic process P
IMP
AthIDH1
IDH2
ISO
MmuMGI:2158650
TAS
SceS000004982
GO:0006103 2-oxoglutarate metabolic process P
ISO
MmuMGI:2158650
GO:0006537 glutamate biosynthetic process P
TAS
SceS000004982
GO:0006734 NADH metabolic process P
ISO
MmuMGI:2158650
GO:0008152 metabolic process P
ISS
AthIDH2
IDH1
GO:0051186 cofactor metabolic process P
RCA
SceS000004982
GO:0055114 oxidation reduction P
RCA
SceS000004982

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1720

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga9692 ENSANGP00000010336
Anopheles gambiae (Aga) aga4326 ENSANGP00000013512
Ashbya gossypii (Ago) ago1518 ADL223W
Arabidopsis thaliana (Ath) ath8554 At2g17130.1
Arabidopsis thaliana (Ath) ath8555 At2g17130.2
Arabidopsis thaliana (Ath) ath21675 At4g35260.1
Arabidopsis thaliana (Ath) ath21722 At4g35650.1
Caenorhabditis elegans (Cel) cel3060 C30F12.7
(CE16887;
WBGene00016266)
Caenorhabditis elegans (Cel) cel3650 C37E2.1
(CE08620;
WBGene00007993)
Caenorhabditis elegans (Cel) cel8183 F35G12.2
(CE31500;
WBGene00009440)
Candida glabrata (Cgl) cgl1740 CAGL0G02673g
Cryptococcus neoformans (Cne) cne3958 185.m02550
Dictyostelium discoideum (Ddi) ddi13561 DDB0231294
Debaryomyces hansenii (Dha) dha1951 DEHA0C11770g
Drosophila melanogaster (Dme) dme14487 CG5028-PA
(FBgn0039358)
Drosophila melanogaster (Dme) dme13774 CG6439-PA
(FBgn0038922)
Danio rerio (Dre) dre17174 ENSDARP00000023516
Takifugu rubripes (Fru) fru18431 SINFRUP00000161887
Takifugu rubripes (Fru) fru17970 SINFRUP00000168718
Takifugu rubripes (Fru) fru17971 SINFRUP00000175788
Gallus gallus (Gga) gga27276 ENSGALP00000023363
(RCJMB04_9n20)		 Q5ZKN9
Homo sapiens (Hsa) hsa33608 ENSP00000217901
(IDH3G)		 P51553
Homo sapiens (Hsa) hsa19690 ENSP00000245969
Homo sapiens (Hsa) hsa19691 ENSP00000344793
Kluyveromyces lactis (Kla) kla4266 KLLA0F04103g
Mus musculus (Mmu) mmu15500 ENSMUSP00000028892
(MGI:2158650)		 Q91VA7
Mus musculus (Mmu) mmu29136 ENSMUSP00000056502
(MGI:1099463)		 P70404
Neurospora crassa (Ncr) ncr753 NCU00775.2
Oryza sativa (Osa) osa6339 2447.m00175
Oryza sativa (Osa) osa42636 5414.m00225
Rattus norvegicus (Rno) rno19717 ENSRNOP00000009681
(RGD:621881)		 Q68FX0
Saccharomyces cerevisiae (Sce) sce5146 YNL037C
(S000004982)
Schizosaccharomyces pombe (Spo) spo4791 SPAC11G7.03 O13696
Yarrowia lipolytica (Yli) yli4075 YALI0E05137g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SpoSPAC11G7.03
GO:0005739 mitochondrion C
IDA
AthAt4g35650
At2g17130
At4g35260
MmuMGI:2158650
MGI:1099463
SceS000004982
ISS
DmeFBgn0038922
FBgn0039358
GO:0005759 mitochondrial matrix C
IDA
SceS000004982
ISS
DmeFBgn0039358
SpoSPAC11G7.03
GO:0005875 microtubule associated complex C
IDA
DmeFBgn0038922
FBgn0039358
GO:0005962 mitochondrial isocitrate dehydrogenase complex
(NAD+)		 C
IDA
SceS000004982
GO:0042645 mitochondrial nucleoid C
IDA
SceS000004982
GO:0004449 isocitrate dehydrogenase (NAD+)
activity		 F
IDA
SceS000004982
IGI
AthAt4g35650
IMP
SpoSPAC11G7.03
ISO
MmuMGI:2158650
MGI:1099463
ISS
AthAt4g35650
At4g35260
At2g17130
DmeFBgn0039358
FBgn0038922
GO:0008270 zinc ion binding F
IDA
AthAt4g35260
GO:0000003 reproduction P
IMP
CelWBGene00009440
GO:0006099 tricarboxylic acid cycle P
IMP
SpoSPAC11G7.03
ISO
MmuMGI:2158650
MGI:1099463
ISS
DmeFBgn0038922
FBgn0039358
TAS
AthAt4g35260
At4g35650
At2g17130
SceS000004982
GO:0006102 isocitrate metabolic process P
IGI
AthAt4g35650
IMP
AthAt2g17130
At4g35260
SpoSPAC11G7.03
ISO
MmuMGI:1099463
MGI:2158650
TAS
SceS000004982
GO:0006103 2-oxoglutarate metabolic process P
ISO
MmuMGI:2158650
MGI:1099463
GO:0006537 glutamate biosynthetic process P
IMP
SpoSPAC11G7.03
TAS
SceS000004982
GO:0006734 NADH metabolic process P
ISO
MmuMGI:2158650
MGI:1099463
GO:0008152 metabolic process P
ISS
AthAt4g35260
At2g17130
At4g35650
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00009440
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00009440
GO:0045926 negative regulation of growth P
ISO
MmuMGI:1099463
GO:0051186 cofactor metabolic process P
RCA
SceS000004982
GO:0055114 oxidation reduction P
RCA
SceS000004982

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC11G7.03
(O13696)		 YNL037C
(S000004982)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SpoSPAC11G7.03
GO:0005739 mitochondrion C
IDA
SceS000004982
GO:0005759 mitochondrial matrix C
IDA
SceS000004982
ISS
SpoSPAC11G7.03
GO:0005962 mitochondrial isocitrate dehydrogenase complex
(NAD+)		 C
IDA
SceS000004982
GO:0042645 mitochondrial nucleoid C
IDA
SceS000004982
GO:0004449 isocitrate dehydrogenase (NAD+)
activity		 F
IDA
SceS000004982
IMP
SpoSPAC11G7.03
GO:0006099 tricarboxylic acid cycle P
IMP
SpoSPAC11G7.03
TAS
SceS000004982
GO:0006102 isocitrate metabolic process P
IMP
SpoSPAC11G7.03
TAS
SceS000004982
GO:0006537 glutamate biosynthetic process P
IMP
SpoSPAC11G7.03
TAS
SceS000004982
GO:0051186 cofactor metabolic process P
RCA
SceS000004982
GO:0055114 oxidation reduction P
RCA
SceS000004982

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