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Search term: YNL062C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name GCD10
SGD link S000005006
Alternative ID YNL062C
Description Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p, required for the modification of the adenine at position 58 in tRNAs, especially tRNAi-Met; first identified as a negative regulator of GCN4 expression
Synonyms YNL062C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1416 ACDHYP-

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING tRNA(1-methyladenosine) methyltransferase, subunit GCD10

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g45730 GI:18406875
Caenorhabditis elegans (Cel) CE15433 GI:17511121
Drosophila melanogaster (Dme) 7297137 GI:7297137
Homo sapiens (Hsa) Hs19923475
(TRMT6)		 GI:19923475 Q9UJA5
Saccharomyces cerevisiae (Sce) YNL062c
(S000005006)		 GI:6324267 P41814
Schizosaccharomyces pombe (Spo) SPBC800.08 GI:19111901 Q9HGL4


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt2g45730
GO:0005634 nucleus C
IDA
SceS000005006
SpoSPBC800.08
ISS
SpoSPBC800.08
GO:0031515 tRNA (m1A) methyltransferase complex C
IDA
SceS000005006
IPI
SceS000005006
ISS
SpoSPBC800.08
GO:0000049 tRNA binding F
IDA
SceS000005006
ISS
SpoSPBC800.08
GO:0003743 translation initiation factor activity F
ISS
AthAt2g45730
GO:0005515 protein binding F
IPI
HsaTRMT6
GO:0016429 tRNA (adenine-N1-)-methyltransferase
activity		 F
IDA
SceS000005006
ISS
SpoSPBC800.08
GO:0006413 translational initiation P
ISS
SpoSPBC800.08
TAS
SceS000005006
GO:0006446 regulation of translational initiation P
ISS
AthAt2g45730
GO:0009451 RNA modification P
RCA
SceS000005006
GO:0030488 tRNA methylation P
IDA
SceS000005006
ISS
SpoSPBC800.08

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
101633

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) gcd10
(SPBC800.08)		 GI:19111901 Q9HGL4
Saccharomyces cerevisiae (Sce) GCD10
(S000005006)		 GI:6324267 P41814
Kluyveromyces lactis (Kla) KLLA0F03377g GI:50310427
Eremothecium gossypii (Ego) AGOS_ADL255C GI:45187618
Magnaporthe grisea (Mgr) MGG_00308 GI:145611542
Neurospora crassa (Ncr) NCU09571.1 GI:32418904


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000005006
SpoSPBC800.08
ISS
SpoSPBC800.08
GO:0031515 tRNA (m1A) methyltransferase complex C
IDA
SceS000005006
IPI
SceS000005006
ISS
SpoSPBC800.08
GO:0000049 tRNA binding F
IDA
SceS000005006
ISS
SpoSPBC800.08
GO:0016429 tRNA (adenine-N1-)-methyltransferase
activity		 F
IDA
SceS000005006
ISS
SpoSPBC800.08
GO:0006413 translational initiation P
ISS
SpoSPBC800.08
TAS
SceS000005006
GO:0009451 RNA modification P
RCA
SceS000005006
GO:0030488 tRNA methylation P
IDA
SceS000005006
ISS
SpoSPBC800.08

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2433

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga12191 ENSANGP00000013316
Ashbya gossypii (Ago) ago1486 ADL255C
Arabidopsis thaliana (Ath) ath11797 At2g45730.1
Caenorhabditis elegans (Cel) cel22299 ZK858.7
(CE35204;
WBGene00014120)
Candida glabrata (Cgl) cgl3430 CAGL0J10010g
Cryptococcus neoformans (Cne) cne5320 179.m00171
Dictyostelium discoideum (Ddi) ddi5269 DDB0204062
Debaryomyces hansenii (Dha) dha5382 DEHA0F22396g
Drosophila melanogaster (Dme) dme1082 CG9596-PA
(FBgn0031832)
Drosophila melanogaster (Dme) dme1083 CG9596-PB
(FBgn0031832)
Danio rerio (Dre) dre13095 ENSDARP00000016271
Gallus gallus (Gga) gga14530 ENSGALP00000014919
(TRMT6)
Homo sapiens (Hsa) hsa19797 ENSP00000203001
(TRMT6)		 Q9UJA5-1
Homo sapiens (Hsa) hsa19798 ENSP00000350055
Kluyveromyces lactis (Kla) kla4233 KLLA0F03377g
Mus musculus (Mmu) mmu15566 ENSMUSP00000044687
(MGI:1914176)		 Q8CE96-1
Neurospora crassa (Ncr) ncr9316 NCU09571.2
Oryza sativa (Osa) osa81510 8127.m00115
Oryza sativa (Osa) osa83646 8252.m00088
Plasmodium falciparum (Pfa) pfa4592 PFI0625c
Rattus norvegicus (Rno) rno19797 ENSRNOP00000028893
(RGD:1308877)
Saccharomyces cerevisiae (Sce) sce5173 YNL062C
(S000005006)
Schizosaccharomyces pombe (Spo) spo4101 SPBC800.08 Q9HGL4
Yarrowia lipolytica (Yli) yli1174 YALI0B10582g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt2g45730
MmuMGI:1914176
GO:0005634 nucleus C
IDA
SceS000005006
SpoSPBC800.08
ISS
SpoSPBC800.08
GO:0031515 tRNA (m1A) methyltransferase complex C
IDA
SceS000005006
IPI
SceS000005006
ISS
SpoSPBC800.08
GO:0000049 tRNA binding F
IDA
SceS000005006
ISS
SpoSPBC800.08
GO:0003674 molecular_function F
ND
MmuMGI:1914176
GO:0003743 translation initiation factor activity F
ISS
AthAt2g45730
GO:0016429 tRNA (adenine-N1-)-methyltransferase
activity		 F
IDA
SceS000005006
ISS
SpoSPBC800.08
GO:0000003 reproduction P
IMP
CelWBGene00014120
GO:0006413 translational initiation P
ISS
SpoSPBC800.08
TAS
SceS000005006
GO:0006446 regulation of translational initiation P
ISS
AthAt2g45730
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00014120
GO:0008150 biological_process P
ND
MmuMGI:1914176
GO:0009451 RNA modification P
RCA
SceS000005006
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00014120
GO:0010171 body morphogenesis P
IMP
CelWBGene00014120
GO:0030488 tRNA methylation P
IDA
SceS000005006
ISS
SpoSPBC800.08
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00014120

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC800.08
(Q9HGL4)		 YNL062C
(S000005006)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000005006
SpoSPBC800.08
ISS
SpoSPBC800.08
GO:0031515 tRNA (m1A) methyltransferase complex C
IDA
SceS000005006
IPI
SceS000005006
ISS
SpoSPBC800.08
GO:0000049 tRNA binding F
IDA
SceS000005006
ISS
SpoSPBC800.08
GO:0016429 tRNA (adenine-N1-)-methyltransferase
activity		 F
IDA
SceS000005006
ISS
SpoSPBC800.08
GO:0006413 translational initiation P
ISS
SpoSPBC800.08
TAS
SceS000005006
GO:0009451 RNA modification P
RCA
SceS000005006
GO:0030488 tRNA methylation P
IDA
SceS000005006
ISS
SpoSPBC800.08

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