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Search term: YNL077W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name APJ1
SGD link S000005021
Alternative ID YNL077W
Description Putative chaperone of the HSP40 (DNAJ) family; overexpression interferes with propagation of the [Psi+] prion; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies
Synonyms YNL077W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0712 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Molecular chaperone (DnaJ superfamily)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g72070 GI:12322203
Arabidopsis thaliana (Ath) At2g17880 GI:15227919
Arabidopsis thaliana (Ath) At3g13310 GI:15231204
Arabidopsis thaliana (Ath) At3g44110 GI:15229874
Arabidopsis thaliana (Ath) At4g13830 GI:15236355
Arabidopsis thaliana (Ath) At4g36040 GI:15233446
Caenorhabditis elegans (Cel) CE13229
(WBGene00001037)		 GI:17563890 O16303
Caenorhabditis elegans (Cel) CE16015
(WBGene00001030)		 GI:17507263 O45502
Caenorhabditis elegans (Cel) CE17461 GI:17558182
Drosophila melanogaster (Dme) 7296520 GI:7296520
Drosophila melanogaster (Dme) 7298006 GI:20129487 Q9VK35
Drosophila melanogaster (Dme) 7299759 GI:7299759 Q9VFV9
Homo sapiens (Hsa) Hs17454448 GI:17454448
Homo sapiens (Hsa) Hs22043937 GI:22043937
Homo sapiens (Hsa) Hs22043974_2 GI:22043974
Homo sapiens (Hsa) Hs22056086 GI:22056086
Homo sapiens (Hsa) Hs4504511
(DNAJA1)		 GI:4504511 P31689
Homo sapiens (Hsa) Hs5031741
(DNAJA2)		 GI:5031741 O60884
Homo sapiens (Hsa) Hs8924044 GI:8924044
Saccharomyces cerevisiae (Sce) YLR090w
(S000004080)		 GI:6323119 P39102
Saccharomyces cerevisiae (Sce) YMR214w
(S000004827)		 GI:6323870
Saccharomyces cerevisiae (Sce) YNL064c
(S000005008)		 GI:6324265 P25491
Saccharomyces cerevisiae (Sce) YNL077w
(S000005021)		 GI:6324252 P53940
Schizosaccharomyces pombe (Spo) SPBC1347.05c GI:19113489 O94625
Schizosaccharomyces pombe (Spo) SPBC1734.11 GI:19112220 O74752
Schizosaccharomyces pombe (Spo) SPBC405.06 GI:19113101 O94657
Encephalitozoon cuniculi (Ecu) ECU07g0760 GI:19074498 Q8SRK0
Arabidopsis thaliana (Ath) At1g72070 GI:12322203
Arabidopsis thaliana (Ath) At2g17880 GI:15227919
Arabidopsis thaliana (Ath) At3g13310 GI:15231204
Arabidopsis thaliana (Ath) At3g44110 GI:15229874
Arabidopsis thaliana (Ath) At4g13830 GI:15236355
Arabidopsis thaliana (Ath) At4g36040 GI:15233446
Caenorhabditis elegans (Cel) CE13229
(WBGene00001037)		 GI:17563890 O16303
Caenorhabditis elegans (Cel) CE16015
(WBGene00001030)		 GI:17507263 O45502
Caenorhabditis elegans (Cel) CE17461 GI:17558182
Drosophila melanogaster (Dme) 7296520 GI:7296520
Drosophila melanogaster (Dme) 7298006 GI:20129487 Q9VK35
Drosophila melanogaster (Dme) 7299759 GI:7299759 Q9VFV9
Homo sapiens (Hsa) Hs17454448 GI:17454448
Homo sapiens (Hsa) Hs22043937 GI:22043937
Homo sapiens (Hsa) Hs22043974_2 GI:22043974
Homo sapiens (Hsa) Hs22056086 GI:22056086
Homo sapiens (Hsa) Hs4504511
(DNAJA1)		 GI:4504511 P31689
Homo sapiens (Hsa) Hs5031741
(DNAJA2)		 GI:5031741 O60884
Homo sapiens (Hsa) Hs8924044 GI:8924044
Saccharomyces cerevisiae (Sce) YLR090w
(S000004080)		 GI:6323119 P39102
Saccharomyces cerevisiae (Sce) YMR214w
(S000004827)		 GI:6323870
Saccharomyces cerevisiae (Sce) YNL064c
(S000005008)		 GI:6324265 P25491
Saccharomyces cerevisiae (Sce) YNL077w
(S000005021)		 GI:6324252 P53940
Schizosaccharomyces pombe (Spo) SPBC1347.05c GI:19113489 O94625
Schizosaccharomyces pombe (Spo) SPBC1734.11 GI:19112220 O74752
Schizosaccharomyces pombe (Spo) SPBC405.06 GI:19113101 O94657
Encephalitozoon cuniculi (Ecu) ECU07g0760 GI:19074498 Q8SRK0


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005618 cell wall C
IDA
AthAt3g44110
GO:0005634 nucleus C
IDA
AthAt4g13830
At4g36040
SceS000004080
S000005021
SpoSPBC1734.11
ISS
SpoSPBC405.06
GO:0005730 nucleolus C
IDA
AthAt3g44110
GO:0005737 cytoplasm C
IDA
SceS000005021
SpoSPBC405.06
GO:0005739 mitochondrion C
IDA
SceS000004080
S000005021
ISS
SpoSPBC405.06
GO:0005783 endoplasmic reticulum C
IDA
SpoSPBC405.06
GO:0005788 endoplasmic reticulum lumen C
IDA
SceS000004827
ISS
SpoSPBC1347.05c
GO:0005792 microsome C
IDA
SceS000005008
GO:0005829 cytosol C
IDA
SceS000005008
SpoSPBC1734.11
ISS
SpoSPBC1734.11
GO:0005886 plasma membrane C
IDA
AthAt3g44110
GO:0031307 integral to mitochondrial outer
membrane		 C
IDA
SceS000004080
GO:0048471 perinuclear region of cytoplasm C
IDA
SceS000005008
GO:0001671 ATPase activator activity F
IDA
SceS000005008
RCA
SceS000005021
GO:0005515 protein binding F
IPI
HsaDNAJA1
ISS
AthAt3g44110
GO:0030544 Hsp70 protein binding F
ISS
SpoSPBC1347.05c
SPBC405.06
SPBC1734.11
GO:0050750 low-density lipoprotein receptor
binding		 F
IDA
HsaDNAJA1
GO:0051082 unfolded protein binding F
IDA
SceS000005008
IMP
SceS000005021
ISS
SceS000005021
RCA
SceS000004827
GO:0051087 chaperone binding F
IMP
SceS000004827
ISS
SceS000004080
S000004827
GO:0006457 protein folding P
IMP
SceS000004827
ISS
AthAt2g17880
At4g13830
At3g44110
At1g72070
At4g36040
At3g13310
SceS000004080
SpoSPBC1347.05c
RCA
SceS000005008
GO:0006458 'de novo' protein folding P
IMP
SceS000005008
GO:0006626 protein targeting to mitochondrion P
IMP
SceS000005008
ISS
SpoSPBC1734.11
GO:0006950 response to stress P
IMP
AthAt4g13830
At4g36040
GO:0006986 response to unfolded protein P
IMP
SceS000004827
TAS
HsaDNAJA1
GO:0007052 mitotic spindle organization P
IMP
CelWBGene00001030
GO:0008150 biological_process P
ND
SceS000005021
GO:0008284 positive regulation of cell proliferation P
TAS
HsaDNAJA2
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00001037
WBGene00001030
GO:0009651 response to salt stress P
IMP
AthAt3g44110
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00001030
GO:0030433 ER-associated protein catabolic
process		 P
IGI
SceS000005008
IMP
SceS000004827
S000005008
ISS
SpoSPBC1347.05c
SPBC1734.11
GO:0034620 cellular response to unfolded protein P
ISS
SpoSPBC1347.05c
GO:0042026 protein refolding P
IDA
SceS000005008
GO:0043462 regulation of ATPase activity P
IMP
AthAt3g44110
GO:0045047 protein targeting to ER P
IMP
SceS000005008
ISS
SpoSPBC1734.11

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
56304

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) APJ1
(S000005021)		 GI:6324252 P53940
Kluyveromyces lactis (Kla) KLLA0E07876g GI:50308607
Eremothecium gossypii (Ego) AGOS_AER427W GI:45191028


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000005021
GO:0005737 cytoplasm C
IDA
SceS000005021
GO:0005739 mitochondrion C
IDA
SceS000005021
GO:0001671 ATPase activator activity F
RCA
SceS000005021
GO:0051082 unfolded protein binding F
IMP
SceS000005021
ISS
SceS000005021
GO:0008150 biological_process P
ND
SceS000005021

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_24686

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago2927 AER427W
Candida glabrata (Cgl) cgl3444 CAGL0J10296g
Debaryomyces hansenii (Dha) dha540 DEHA0A12045g
Kluyveromyces lactis (Kla) kla3305 KLLA0E07876g
Saccharomyces cerevisiae (Sce) sce5190 YNL077W
(S000005021)


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000005021
GO:0005737 cytoplasm C
IDA
SceS000005021
GO:0005739 mitochondrion C
IDA
SceS000005021
GO:0001671 ATPase activator activity F
RCA
SceS000005021
GO:0051082 unfolded protein binding F
IMP
SceS000005021
ISS
SceS000005021
GO:0008150 biological_process P
ND
SceS000005021

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