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Search term: YNL079C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name TPM1
SGD link S000005023
Alternative ID YNL079C
Description Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments, which direct polarized cell growth and the distribution of several organelles; acetylated by the NatB complex and acetylated form binds actin most efficiently
Synonyms YNL079C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

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Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1003 -CDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Actin filament-coating protein tropomyosin

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE28782
(WBGene00002978)		 GI:17510803
Caenorhabditis elegans (Cel) CE29058 GI:17510809
Caenorhabditis elegans (Cel) CE29059 GI:17510805
Caenorhabditis elegans (Cel) CE29060 GI:17510807
Drosophila melanogaster (Dme) 7299991 GI:7299991
Drosophila melanogaster (Dme) 7299992 GI:7299992
Drosophila melanogaster (Dme) 7299993 GI:17737977
Homo sapiens (Hsa) Hs14729747 GI:14729747
Homo sapiens (Hsa) Hs17462853 GI:17462853
Homo sapiens (Hsa) Hs17482462 GI:17482462
Homo sapiens (Hsa) Hs17490014 GI:17490014
Homo sapiens (Hsa) Hs18553161 GI:18553161
Homo sapiens (Hsa) Hs18585091 GI:18585091
Homo sapiens (Hsa) Hs18590249 GI:18590249
Homo sapiens (Hsa) Hs20070123 GI:20070123
Homo sapiens (Hsa) Hs20539050 GI:20539050
Homo sapiens (Hsa) Hs20539300 GI:20539300
Homo sapiens (Hsa) Hs20539590 GI:20539590
Homo sapiens (Hsa) Hs20545089 GI:20545089
Homo sapiens (Hsa) Hs4507649 GI:4507649
Homo sapiens (Hsa) Hs4507651 GI:4507651 Q9UCS3
Saccharomyces cerevisiae (Sce) YIL138c
(S000001400)		 GI:6322053 P40414
Saccharomyces cerevisiae (Sce) YNL079c
(S000005023)		 GI:6324250 P17536
Schizosaccharomyces pombe (Spo) SPAC27F1.02c GI:19115442 Q02088
Caenorhabditis elegans (Cel) CE28782
(WBGene00002978)		 GI:17510803
Caenorhabditis elegans (Cel) CE29058 GI:17510809
Caenorhabditis elegans (Cel) CE29059 GI:17510805
Caenorhabditis elegans (Cel) CE29060 GI:17510807
Drosophila melanogaster (Dme) 7299991 GI:7299991
Drosophila melanogaster (Dme) 7299992 GI:7299992
Drosophila melanogaster (Dme) 7299993 GI:17737977
Homo sapiens (Hsa) Hs14729747 GI:14729747
Homo sapiens (Hsa) Hs17462853 GI:17462853
Homo sapiens (Hsa) Hs17482462 GI:17482462
Homo sapiens (Hsa) Hs17490014 GI:17490014
Homo sapiens (Hsa) Hs18553161 GI:18553161
Homo sapiens (Hsa) Hs18585091 GI:18585091
Homo sapiens (Hsa) Hs18590249 GI:18590249
Homo sapiens (Hsa) Hs20070123 GI:20070123
Homo sapiens (Hsa) Hs20539050 GI:20539050
Homo sapiens (Hsa) Hs20539300 GI:20539300
Homo sapiens (Hsa) Hs20539590 GI:20539590
Homo sapiens (Hsa) Hs20545089 GI:20545089
Homo sapiens (Hsa) Hs4507649 GI:4507649
Homo sapiens (Hsa) Hs4507651 GI:4507651 Q9UCS3
Saccharomyces cerevisiae (Sce) YIL138c
(S000001400)		 GI:6322053 P40414
Saccharomyces cerevisiae (Sce) YNL079c
(S000005023)		 GI:6324250 P17536
Schizosaccharomyces pombe (Spo) SPAC27F1.02c GI:19115442 Q02088


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000142 cellular bud neck contractile ring C
IDA
SceS000005023
S000001400
GO:0005737 cytoplasm C
IDA
SpoSPAC27F1.02c
GO:0005826 actomyosin contractile ring C
IDA
SpoSPAC27F1.02c
GO:0005865 striated muscle thin filament C
IDA
CelWBGene00002978
GO:0032432 actin filament bundle C
IDA
SceS000005023
S000001400
SpoSPAC27F1.02c
GO:0003779 actin binding F
TAS
SpoSPAC27F1.02c
GO:0003786 actin lateral binding F
TAS
SceS000005023
S000001400
GO:0051015 actin filament binding F
IDA
CelWBGene00002978
GO:0000001 mitochondrion inheritance P
TAS
SceS000005023
S000001400
GO:0000003 reproduction P
IMP
CelWBGene00002978
GO:0000011 vacuole inheritance P
TAS
SceS000005023
S000001400
GO:0000915 cytokinesis, actomyosin contractile ring
assembly		 P
IMP
SpoSPAC27F1.02c
GO:0002119 nematode larval development P
IMP
CelWBGene00002978
GO:0006887 exocytosis P
TAS
SceS000001400
S000005023
GO:0006984 ER-nucleus signaling pathway P
RCA
SceS000005023
GO:0007015 actin filament organization P
TAS
SceS000005023
S000001400
GO:0007047 cellular cell wall organization P
RCA
SceS000005023
GO:0007118 budding cell apical bud growth P
TAS
SceS000001400
S000005023
GO:0007119 budding cell isotropic bud growth P
TAS
SceS000001400
S000005023
GO:0007124 pseudohyphal growth P
IMP
SceS000005023
GO:0008154 actin polymerization or depolymerization P
TAS
SceS000005023
S000001400
GO:0008298 intracellular mRNA localization P
RCA
SceS000005023
TAS
SceS000001400
S000005023
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00002978
GO:0010171 body morphogenesis P
IMP
CelWBGene00002978
GO:0015031 protein transport P
RCA
SceS000005023
GO:0016192 vesicle-mediated transport P
TAS
SceS000001400
S000005023
GO:0018991 oviposition P
IMP
CelWBGene00002978
GO:0018996 molting cycle, collagen and cuticulin-based
cuticle		 P
IMP
CelWBGene00002978
GO:0030010 establishment of cell polarity P
TAS
SceS000001400
S000005023
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
RCA
SceS000005023
GO:0030447 filamentous growth P
IMP
SceS000005023
GO:0030833 regulation of actin filament polymerization P
IDA
CelWBGene00002978
GO:0032220 plasma membrane fusion involved in
cytogamy		 P
IMP
SpoSPAC27F1.02c
GO:0033205 cell cycle cytokinesis P
IMP
SpoSPAC27F1.02c
GO:0034613 cellular protein localization P
RCA
SceS000005023
GO:0040011 locomotion P
IMP
CelWBGene00002978
GO:0040015 negative regulation of multicellular organism
growth		 P
IMP
CelWBGene00002978
GO:0040017 positive regulation of locomotion P
IMP
CelWBGene00002978
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00002978
GO:0043393 regulation of protein binding P
IDA
CelWBGene00002978
GO:0045184 establishment of protein localization P
RCA
SceS000005023
GO:0048308 organelle inheritance P
RCA
SceS000005023
GO:0051017 actin filament bundle assembly P
IGI
SceS000005023
S000001400
GO:0060465 pharynx development P
IMP
CelWBGene00002978
GO:0071519 actin filament bundle assembly involved in
actomyosin contractile ring formation		 P
NAS
SpoSPAC27F1.02c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
39294

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) cdc8
(SPAC27F1.02c)		 GI:19115442 Q02088
Saccharomyces cerevisiae (Sce) TPM2
(S000001400)		 GI:6322053 P40414
Saccharomyces cerevisiae (Sce) TPM1
(S000005023)		 GI:6324250 P17536
Kluyveromyces lactis (Kla) KLLA0E18007g GI:50312953
Eremothecium gossypii (Ego) AGOS_AER424C GI:119873860
Magnaporthe grisea (Mgr) MGG_08078 GI:39945916
Neurospora crassa (Ncr) NCU01204.1 GI:32412434


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000142 cellular bud neck contractile ring C
IDA
SceS000005023
S000001400
GO:0005737 cytoplasm C
IDA
SpoSPAC27F1.02c
GO:0005826 actomyosin contractile ring C
IDA
SpoSPAC27F1.02c
GO:0032432 actin filament bundle C
IDA
SceS000005023
S000001400
SpoSPAC27F1.02c
GO:0003779 actin binding F
TAS
SpoSPAC27F1.02c
GO:0003786 actin lateral binding F
TAS
SceS000005023
S000001400
GO:0000001 mitochondrion inheritance P
TAS
SceS000005023
S000001400
GO:0000011 vacuole inheritance P
TAS
SceS000005023
S000001400
GO:0000915 cytokinesis, actomyosin contractile ring
assembly		 P
IMP
SpoSPAC27F1.02c
GO:0006887 exocytosis P
TAS
SceS000001400
S000005023
GO:0006984 ER-nucleus signaling pathway P
RCA
SceS000005023
GO:0007015 actin filament organization P
TAS
SceS000005023
S000001400
GO:0007047 cellular cell wall organization P
RCA
SceS000005023
GO:0007118 budding cell apical bud growth P
TAS
SceS000001400
S000005023
GO:0007119 budding cell isotropic bud growth P
TAS
SceS000001400
S000005023
GO:0007124 pseudohyphal growth P
IMP
SceS000005023
GO:0008154 actin polymerization or depolymerization P
TAS
SceS000005023
S000001400
GO:0008298 intracellular mRNA localization P
RCA
SceS000005023
TAS
SceS000001400
S000005023
GO:0015031 protein transport P
RCA
SceS000005023
GO:0016192 vesicle-mediated transport P
TAS
SceS000001400
S000005023
GO:0030010 establishment of cell polarity P
TAS
SceS000001400
S000005023
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
RCA
SceS000005023
GO:0030447 filamentous growth P
IMP
SceS000005023
GO:0032220 plasma membrane fusion involved in
cytogamy		 P
IMP
SpoSPAC27F1.02c
GO:0033205 cell cycle cytokinesis P
IMP
SpoSPAC27F1.02c
GO:0034613 cellular protein localization P
RCA
SceS000005023
GO:0045184 establishment of protein localization P
RCA
SceS000005023
GO:0048308 organelle inheritance P
RCA
SceS000005023
GO:0051017 actin filament bundle assembly P
IGI
SceS000005023
S000001400
GO:0071519 actin filament bundle assembly involved in
actomyosin contractile ring formation		 P
NAS
SpoSPAC27F1.02c

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1434

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga3921 ENSANGP00000008408
Anopheles gambiae (Aga) aga3918 ENSANGP00000023232
Anopheles gambiae (Aga) aga3919 ENSANGP00000024115
Anopheles gambiae (Aga) aga3923 ENSANGP00000024231
Caenorhabditis elegans (Cel) cel17522 Y105E8B.1a
(CE28782;
WBGene00002978)
Caenorhabditis elegans (Cel) cel17523 Y105E8B.1b
(CE36223)
Caenorhabditis elegans (Cel) cel17525 Y105E8B.1d
(CE29060)
Caenorhabditis elegans (Cel) cel17526 Y105E8B.1e
(CE31733)
Candida glabrata (Cgl) cgl3226 CAGL0J05434g
Drosophila melanogaster (Dme) dme12731 CG4843-PA
(FBgn0004117)
Drosophila melanogaster (Dme) dme12733 CG4843-PB
(FBgn0004117)
Drosophila melanogaster (Dme) dme12732 CG4843-PC
(FBgn0004117)
Drosophila melanogaster (Dme) dme12719 CG4898-PB
(FBgn0003721)
Drosophila melanogaster (Dme) dme12728 CG4898-PC
(FBgn0003721)
Drosophila melanogaster (Dme) dme12721 CG4898-PD
(FBgn0003721)
Drosophila melanogaster (Dme) dme12723 CG4898-PE
(FBgn0003721)
Drosophila melanogaster (Dme) dme12725 CG4898-PF
(FBgn0003721)
Drosophila melanogaster (Dme) dme12722 CG4898-PG
(FBgn0003721)
Drosophila melanogaster (Dme) dme12727 CG4898-PH
(FBgn0003721)
Drosophila melanogaster (Dme) dme12729 CG4898-PI
(FBgn0003721)
Drosophila melanogaster (Dme) dme12720 CG4898-PJ
(FBgn0003721)
Drosophila melanogaster (Dme) dme12724 CG4898-PK
(FBgn0003721)
Drosophila melanogaster (Dme) dme12726 CG4898-PL
(FBgn0003721)
Danio rerio (Dre) dre4500 ENSDARP00000004352
(tpm3)
Takifugu rubripes (Fru) fru1142 SINFRUP00000138117
Takifugu rubripes (Fru) fru17246 SINFRUP00000144396
Takifugu rubripes (Fru) fru9599 SINFRUP00000152989
Gallus gallus (Gga) gga3757 ENSGALP00000005561
Homo sapiens (Hsa) hsa2124 ENSP00000271850
(TPM3)		 P06753-1
Homo sapiens (Hsa) hsa10743 ENSP00000334624
(TPM1)		 P09493-5
Homo sapiens (Hsa) hsa10744 ENSP00000350667
(TPM1)		 Q6ZN40
Homo sapiens (Hsa) hsa31234 ENSP00000354219
(TPM2)		 P07951-1
Mus musculus (Mmu) mmu16996 ENSMUSP00000029550
(MGI:1890149)		 P21107-1
Mus musculus (Mmu) mmu18036 ENSMUSP00000030184
(MGI:98810)		 P58774-1
Mus musculus (Mmu) mmu27861 ENSMUSP00000071067
Rattus norvegicus (Rno) rno28850 ENSRNOP00000024575
(RGD:3898)		 P04692-3
Rattus norvegicus (Rno) rno28849 ENSRNOP00000024617
(RGD:3898)		 P04692-7
Rattus norvegicus (Rno) rno16450 ENSRNOP00000035561
(RGD:621546)		 O88440
Saccharomyces cerevisiae (Sce) sce5192 YNL079C
(S000005023)


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000142 cellular bud neck contractile ring C
IDA
SceS000005023
GO:0001725 stress fiber C
ISO
MmuMGI:1890149
GO:0002102 podosome C
IDA
MmuMGI:1890149
GO:0005737 cytoplasm C
IDA
MmuMGI:1890149
GO:0005862 muscle thin filament tropomyosin C
NAS
DmeFBgn0003721
FBgn0004117
TAS
MmuMGI:98810
GO:0005865 striated muscle thin filament C
IDA
CelWBGene00002978
GO:0030017 sarcomere C
IDA
DmeFBgn0003721
GO:0030426 growth cone C
IDA
MmuMGI:1890149
GO:0030863 cortical cytoskeleton C
IDA
MmuMGI:1890149
GO:0031941 filamentous actin C
IDA
MmuMGI:1890149
GO:0032154 cleavage furrow C
IDA
MmuMGI:1890149
GO:0032432 actin filament bundle C
IDA
SceS000005023
GO:0043005 neuron projection C
IDA
MmuMGI:1890149
GO:0003779 actin binding F
ISS
DmeFBgn0003721
FBgn0004117
TAS
DmeFBgn0003721
GO:0003786 actin lateral binding F
TAS
SceS000005023
GO:0005200 structural constituent of cytoskeleton F
TAS
MmuMGI:98810
GO:0005515 protein binding F
IPI
MmuMGI:98810
GO:0051015 actin filament binding F
IDA
CelWBGene00002978
GO:0000001 mitochondrion inheritance P
TAS
SceS000005023
GO:0000003 reproduction P
IMP
CelWBGene00002978
GO:0000011 vacuole inheritance P
TAS
SceS000005023
GO:0002119 nematode larval development P
IMP
CelWBGene00002978
GO:0006887 exocytosis P
TAS
SceS000005023
GO:0006936 muscle contraction P
NAS
DmeFBgn0003721
TAS
MmuMGI:98810
GO:0006984 ER-nucleus signaling pathway P
RCA
SceS000005023
GO:0007015 actin filament organization P
TAS
SceS000005023
GO:0007047 cellular cell wall organization P
RCA
SceS000005023
GO:0007118 budding cell apical bud growth P
TAS
SceS000005023
GO:0007119 budding cell isotropic bud growth P
TAS
SceS000005023
GO:0007124 pseudohyphal growth P
IMP
SceS000005023
GO:0007315 pole plasm assembly P
NAS
DmeFBgn0003721
GO:0007507 heart development P
IMP
DmeFBgn0004117
GO:0008154 actin polymerization or depolymerization P
TAS
SceS000005023
GO:0008298 intracellular mRNA localization P
RCA
SceS000005023
TAS
SceS000005023
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00002978
GO:0010171 body morphogenesis P
IMP
CelWBGene00002978
GO:0010591 regulation of lamellipodium assembly P
IMP
DmeFBgn0003721
GO:0015031 protein transport P
RCA
SceS000005023
GO:0016192 vesicle-mediated transport P
TAS
SceS000005023
GO:0018991 oviposition P
IMP
CelWBGene00002978
GO:0018996 molting cycle, collagen and cuticulin-based
cuticle		 P
IMP
CelWBGene00002978
GO:0030010 establishment of cell polarity P
TAS
SceS000005023
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
RCA
SceS000005023
GO:0030447 filamentous growth P
IMP
SceS000005023
GO:0030833 regulation of actin filament polymerization P
IDA
CelWBGene00002978
GO:0034613 cellular protein localization P
RCA
SceS000005023
GO:0040011 locomotion P
IMP
CelWBGene00002978
GO:0040015 negative regulation of multicellular organism
growth		 P
IMP
CelWBGene00002978
GO:0040017 positive regulation of locomotion P
IMP
CelWBGene00002978
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00002978
GO:0043393 regulation of protein binding P
IDA
CelWBGene00002978
GO:0045184 establishment of protein localization P
RCA
SceS000005023
GO:0045451 pole plasm oskar mRNA localization P
IMP
DmeFBgn0003721
TAS
DmeFBgn0003721
GO:0048308 organelle inheritance P
RCA
SceS000005023
GO:0048477 oogenesis P
TAS
DmeFBgn0003721
GO:0048813 dendrite morphogenesis P
IMP
DmeFBgn0003721
TAS
DmeFBgn0003721
GO:0051017 actin filament bundle assembly P
IGI
SceS000005023
GO:0060465 pharynx development P
IMP
CelWBGene00002978

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC27F1.02c
(Q02088)		 YNL079C
(S000005023)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000142 cellular bud neck contractile ring C
IDA
SceS000005023
GO:0005737 cytoplasm C
IDA
SpoSPAC27F1.02c
GO:0005826 actomyosin contractile ring C
IDA
SpoSPAC27F1.02c
GO:0032432 actin filament bundle C
IDA
SceS000005023
SpoSPAC27F1.02c
GO:0003779 actin binding F
TAS
SpoSPAC27F1.02c
GO:0003786 actin lateral binding F
TAS
SceS000005023
GO:0000001 mitochondrion inheritance P
TAS
SceS000005023
GO:0000011 vacuole inheritance P
TAS
SceS000005023
GO:0000915 cytokinesis, actomyosin contractile ring
assembly		 P
IMP
SpoSPAC27F1.02c
GO:0006887 exocytosis P
TAS
SceS000005023
GO:0006984 ER-nucleus signaling pathway P
RCA
SceS000005023
GO:0007015 actin filament organization P
TAS
SceS000005023
GO:0007047 cellular cell wall organization P
RCA
SceS000005023
GO:0007118 budding cell apical bud growth P
TAS
SceS000005023
GO:0007119 budding cell isotropic bud growth P
TAS
SceS000005023
GO:0007124 pseudohyphal growth P
IMP
SceS000005023
GO:0008154 actin polymerization or depolymerization P
TAS
SceS000005023
GO:0008298 intracellular mRNA localization P
RCA
SceS000005023
TAS
SceS000005023
GO:0015031 protein transport P
RCA
SceS000005023
GO:0016192 vesicle-mediated transport P
TAS
SceS000005023
GO:0030010 establishment of cell polarity P
TAS
SceS000005023
GO:0030435 sporulation resulting in formation of a cellular
spore		 P
RCA
SceS000005023
GO:0030447 filamentous growth P
IMP
SceS000005023
GO:0032220 plasma membrane fusion involved in
cytogamy		 P
IMP
SpoSPAC27F1.02c
GO:0033205 cell cycle cytokinesis P
IMP
SpoSPAC27F1.02c
GO:0034613 cellular protein localization P
RCA
SceS000005023
GO:0045184 establishment of protein localization P
RCA
SceS000005023
GO:0048308 organelle inheritance P
RCA
SceS000005023
GO:0051017 actin filament bundle assembly P
IGI
SceS000005023
GO:0071519 actin filament bundle assembly involved in
actomyosin contractile ring formation		 P
NAS
SpoSPAC27F1.02c

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Query species:

Include wild-cards:   

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GO info in one table:

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