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Search term: YNL088W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name TOP2
SGD link S000005032
Alternative ID YNL088W
Description Essential type II topoisomerase, relieves torsional strain in DNA by cleaving and re-sealing the phosphodiester backbone of both positively and negatively supercoiled DNA; cleaves complementary strands; localizes to axial cores in meiosis
Synonyms YNL088W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0355 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING DNA topoisomerase type II

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g13720 GI:15225481
Arabidopsis thaliana (Ath) At3g10270 GI:15228245
Arabidopsis thaliana (Ath) At3g10690 GI:15228353
Arabidopsis thaliana (Ath) At3g23890 GI:15229538
Arabidopsis thaliana (Ath) At5g04110 GI:15237631
Arabidopsis thaliana (Ath) At5g04130 GI:9955568
Arabidopsis thaliana (Ath) At5g53960 GI:15238884
Caenorhabditis elegans (Cel) CE01933 GI:17533601
Caenorhabditis elegans (Cel) CE06184
(WBGene00010785)		 GI:17535065 Q23670
Caenorhabditis elegans (Cel) CE07645 GI:17538047
Caenorhabditis elegans (Cel) CE17740 GI:17533625
Caenorhabditis elegans (Cel) CE18656 GI:17533627
Caenorhabditis elegans (Cel) CE24315 GI:17565806
Caenorhabditis elegans (Cel) CE25068 GI:17554464
Drosophila melanogaster (Dme) 7298585 GI:7298585
Homo sapiens (Hsa) Hs19913406
(TOP2A)		 GI:19913406 Q9UQP9
Homo sapiens (Hsa) Hs19913408
(TOP2B)		 GI:19913408 Q02880
Saccharomyces cerevisiae (Sce) YNL088w
(S000005032)		 GI:6324241 P06786
Schizosaccharomyces pombe (Spo) SPBC1A4.03c GI:19112597 P08096
Encephalitozoon cuniculi (Ecu) ECU04g0350 GI:19074112 Q8SS63
Arabidopsis thaliana (Ath) At2g13720 GI:15225481
Arabidopsis thaliana (Ath) At3g10270 GI:15228245
Arabidopsis thaliana (Ath) At3g10690 GI:15228353
Arabidopsis thaliana (Ath) At3g23890 GI:15229538
Arabidopsis thaliana (Ath) At5g04110 GI:15237631
Arabidopsis thaliana (Ath) At5g04130 GI:9955568
Arabidopsis thaliana (Ath) At5g53960 GI:15238884
Caenorhabditis elegans (Cel) CE01933 GI:17533601
Caenorhabditis elegans (Cel) CE06184
(WBGene00010785)		 GI:17535065 Q23670
Caenorhabditis elegans (Cel) CE07645 GI:17538047
Caenorhabditis elegans (Cel) CE17740 GI:17533625
Caenorhabditis elegans (Cel) CE18656 GI:17533627
Caenorhabditis elegans (Cel) CE24315 GI:17565806
Caenorhabditis elegans (Cel) CE25068 GI:17554464
Drosophila melanogaster (Dme) 7298585 GI:7298585
Homo sapiens (Hsa) Hs19913406
(TOP2A)		 GI:19913406 Q9UQP9
Homo sapiens (Hsa) Hs19913408
(TOP2B)		 GI:19913408 Q02880
Saccharomyces cerevisiae (Sce) YNL088w
(S000005032)		 GI:6324241 P06786
Schizosaccharomyces pombe (Spo) SPBC1A4.03c GI:19112597 P08096
Encephalitozoon cuniculi (Ecu) ECU04g0350 GI:19074112 Q8SS63
Arabidopsis thaliana (Ath) At2g13720 GI:15225481
Arabidopsis thaliana (Ath) At3g10270 GI:15228245
Arabidopsis thaliana (Ath) At3g10690 GI:15228353
Arabidopsis thaliana (Ath) At3g23890 GI:15229538
Arabidopsis thaliana (Ath) At5g04110 GI:15237631
Arabidopsis thaliana (Ath) At5g04130 GI:9955568
Arabidopsis thaliana (Ath) At5g53960 GI:15238884
Caenorhabditis elegans (Cel) CE01933 GI:17533601
Caenorhabditis elegans (Cel) CE06184
(WBGene00010785)		 GI:17535065 Q23670
Caenorhabditis elegans (Cel) CE07645 GI:17538047
Caenorhabditis elegans (Cel) CE17740 GI:17533625
Caenorhabditis elegans (Cel) CE18656 GI:17533627
Caenorhabditis elegans (Cel) CE24315 GI:17565806
Caenorhabditis elegans (Cel) CE25068 GI:17554464
Drosophila melanogaster (Dme) 7298585 GI:7298585
Homo sapiens (Hsa) Hs19913406
(TOP2A)		 GI:19913406 Q9UQP9
Homo sapiens (Hsa) Hs19913408
(TOP2B)		 GI:19913408 Q02880
Saccharomyces cerevisiae (Sce) YNL088w
(S000005032)		 GI:6324241 P06786
Schizosaccharomyces pombe (Spo) SPBC1A4.03c GI:19112597 P08096
Encephalitozoon cuniculi (Ecu) ECU04g0350 GI:19074112 Q8SS63


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000228 nuclear chromosome C
IDA
HsaTOP2A
NAS
SpoSPBC1A4.03c
GO:0000792 heterochromatin C
IDA
HsaTOP2B
GO:0000795 synaptonemal complex C
IDA
SceS000005032
GO:0005634 nucleus C
IDA
AthAt3g23890
HsaTOP2A
TOP2B
SceS000005032
SpoSPBC1A4.03c
GO:0005654 nucleoplasm C
IDA
HsaTOP2B
TOP2A
GO:0005737 cytoplasm C
IDA
AthAt3g10270
HsaTOP2A
GO:0005739 mitochondrion C
IDA
AthAt3g10690
At5g04130
At3g10270
SceS000005032
GO:0005814 centriole C
IDA
HsaTOP2A
GO:0005829 cytosol C
IDA
HsaTOP2B
GO:0005886 plasma membrane C
IDA
AthAt5g53960
GO:0009295 nucleoid C
IDA
AthAt3g10270
At3g10690
GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing) C
IDA
HsaTOP2A
ISS
AthAt3g23890
GO:0009507 chloroplast C
IDA
AthAt3g10690
At3g10270
GO:0019035 viral integration complex C
NAS
HsaTOP2A
GO:0043234 protein complex C
IPI
HsaTOP2A
GO:0070603 SWI/SNF-type complex C
IDA
HsaTOP2B
GO:0003677 DNA binding F
IDA
HsaTOP2A
ISS
AthAt5g04130
At3g10270
At3g23890
At5g04110
GO:0003682 chromatin binding F
IDA
HsaTOP2B
TOP2A
GO:0003824 catalytic activity F
ISS
AthAt3g10690
GO:0003916 DNA topoisomerase activity F
IGI
AthAt5g04130
At5g04110
At3g10690
ISS
AthAt3g23890
GO:0003918 DNA topoisomerase (ATP-hydrolyzing)
activity		 F
IDA
HsaTOP2A
SceS000005032
SpoSPBC1A4.03c
IGI
SpoSPBC1A4.03c
IMP
SpoSPBC1A4.03c
ISS
AthAt3g10270
At5g04130
At5g04110
At3g23890
GO:0005080 protein kinase C binding F
IPI
HsaTOP2B
TOP2A
GO:0005515 protein binding F
IPI
HsaTOP2A
GO:0005524 ATP binding F
IC
SpoSPBC1A4.03c
ISS
AthAt3g10690
At5g04130
At3g23890
At3g10270
At5g04110
GO:0008022 protein C-terminus binding F
IPI
HsaTOP2B
TOP2A
GO:0008094 DNA-dependent ATPase activity F
IDA
HsaTOP2A
ISS
AthAt3g23890
GO:0008144 drug binding F
IDA
HsaTOP2A
GO:0019899 enzyme binding F
IPI
HsaTOP2A
GO:0042803 protein homodimerization activity F
IPI
HsaTOP2A
GO:0042826 histone deacetylase binding F
IPI
HsaTOP2A
TOP2B
GO:0043130 ubiquitin binding F
IMP
HsaTOP2A
GO:0046982 protein heterodimerization activity F
IPI
HsaTOP2A
TOP2B
GO:0000019 regulation of mitotic recombination P
IMP
SceS000005032
GO:0000712 resolution of meiotic recombination
intermediates		 P
IMP
SpoSPBC1A4.03c
GO:0000910 cytokinesis P
IMP
CelWBGene00010785
GO:0006259 DNA metabolic process P
ISS
AthAt3g10270
At5g04110
At5g04130
At3g23890
GO:0006260 DNA replication P
NAS
HsaTOP2A
GO:0006265 DNA topological change P
IDA
SceS000005032
SpoSPBC1A4.03c
IGI
SpoSPBC1A4.03c
IMP
SpoSPBC1A4.03c
ISS
AthAt3g10270
At5g04130
At3g23890
At5g04110
GO:0006266 DNA ligation P
IDA
HsaTOP2A
GO:0006271 DNA strand elongation involved in DNA
replication		 P
IMP
SceS000005032
ISS
SpoSPBC1A4.03c
GO:0006281 DNA repair P
NAS
HsaTOP2A
GO:0006325 chromatin organization P
IGI
SpoSPBC1A4.03c
GO:0006333 chromatin assembly or disassembly P
IMP
SceS000005032
GO:0006406 mRNA export from nucleus P
IMP
SpoSPBC1A4.03c
GO:0006974 response to DNA damage stimulus P
IDA
HsaTOP2A
GO:0007059 chromosome segregation P
IMP
HsaTOP2A
ISS
AthAt3g23890
GO:0007076 mitotic chromosome condensation P
IMP
SpoSPBC1A4.03c
GO:0007131 reciprocal meiotic recombination P
IMP
SceS000005032
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00010785
GO:0030263 apoptotic chromosome condensation P
IDA
HsaTOP2A
GO:0031055 chromatin remodeling at centromere P
IMP
SceS000005032
GO:0042790 transcription of nuclear rRNA large RNA polymerase
I transcript		 P
IGI
SpoSPBC1A4.03c
GO:0043065 positive regulation of apoptosis P
IDA
HsaTOP2A
GO:0045070 positive regulation of viral genome
replication		 P
IMP
HsaTOP2A
GO:0045870 positive regulation of retroviral genome
replication		 P
IMP
HsaTOP2A
GO:0048015 phosphoinositide-mediated signaling P
NAS
HsaTOP2A
GO:0051301 cell division P
IMP
CelWBGene00010785
GO:0070683 decatenation checkpoint P
IMP
SceS000005032

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
830

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) TOP2A GI:19913406 Q9UQP9
Canis familiaris (Cfa) TOP2A GI:73966009
Mus musculus (Mmu) Top2a
(MGI:98790)		 GI:6755849 Q01320
Rattus norvegicus (Rno) Top2a
(RGD:62048)		 GI:38259192
Gallus gallus (Gga) TOP2A GI:45382161
Caenorhabditis elegans (Cel) top-2
(CE06184;
WBGene00010785)		 GI:17535065 Q23670
Schizosaccharomyces pombe (Spo) ptr11 GI:19112597
Saccharomyces cerevisiae (Sce) TOP2
(S000005032)		 GI:6324241 P06786
Kluyveromyces lactis (Kla) KLLA0C13838g GI:50305715
Eremothecium gossypii (Ego) AGOS_AER410W GI:45191011
Magnaporthe grisea (Mgr) MGG_06162 GI:39975823
Neurospora crassa (Ncr) NCU06338.1 GI:32411425
Arabidopsis thaliana (Ath) TOPII GI:15229538
Oryza sativa (Osa) Os02g0699700 GI:115448107
Plasmodium falciparum (Pfa) PF14_0316 GI:124809097


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000228 nuclear chromosome C
IDA
HsaTOP2A
GO:0000793 condensed chromosome C
IDA
MmuMGI:98790
GO:0000795 synaptonemal complex C
IDA
SceS000005032
GO:0005634 nucleus C
IDA
AthTOPII
HsaTOP2A
MmuMGI:98790
SceS000005032
ISO
MmuMGI:98790
GO:0005654 nucleoplasm C
IDA
HsaTOP2A
GO:0005730 nucleolus C
IDA
MmuMGI:98790
GO:0005737 cytoplasm C
IDA
HsaTOP2A
GO:0005739 mitochondrion C
IDA
SceS000005032
GO:0005814 centriole C
IDA
HsaTOP2A
GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing) C
IDA
HsaTOP2A
ISO
MmuMGI:98790
ISS
AthTOPII
GO:0019035 viral integration complex C
NAS
HsaTOP2A
GO:0043234 protein complex C
IPI
HsaTOP2A
GO:0003677 DNA binding F
IDA
HsaTOP2A
ISS
AthTOPII
GO:0003682 chromatin binding F
IDA
HsaTOP2A
ISO
MmuMGI:98790
GO:0003916 DNA topoisomerase activity F
ISO
MmuMGI:98790
ISS
AthTOPII
GO:0003918 DNA topoisomerase (ATP-hydrolyzing)
activity		 F
IDA
HsaTOP2A
MmuMGI:98790
SceS000005032
IGI
MmuMGI:98790
ISO
MmuMGI:98790
ISS
AthTOPII
GO:0005080 protein kinase C binding F
IPI
HsaTOP2A
GO:0005515 protein binding F
IPI
HsaTOP2A
GO:0005524 ATP binding F
ISO
MmuMGI:98790
ISS
AthTOPII
GO:0008022 protein C-terminus binding F
IPI
HsaTOP2A
GO:0008094 DNA-dependent ATPase activity F
IDA
HsaTOP2A
ISS
AthTOPII
GO:0008144 drug binding F
IDA
HsaTOP2A
GO:0019899 enzyme binding F
IPI
HsaTOP2A
GO:0042803 protein homodimerization activity F
IPI
HsaTOP2A
GO:0042826 histone deacetylase binding F
IPI
HsaTOP2A
GO:0043130 ubiquitin binding F
IMP
HsaTOP2A
GO:0043565 sequence-specific DNA binding F
ISO
MmuMGI:98790
GO:0043566 structure-specific DNA binding F
ISO
MmuMGI:98790
GO:0046982 protein heterodimerization activity F
IPI
HsaTOP2A
GO:0000019 regulation of mitotic recombination P
IMP
SceS000005032
GO:0000910 cytokinesis P
IMP
CelWBGene00010785
GO:0006259 DNA metabolic process P
ISS
AthTOPII
GO:0006260 DNA replication P
NAS
HsaTOP2A
GO:0006265 DNA topological change P
IDA
MmuMGI:98790
SceS000005032
ISO
MmuMGI:98790
ISS
AthTOPII
GO:0006266 DNA ligation P
IDA
HsaTOP2A
GO:0006271 DNA strand elongation involved in DNA
replication		 P
IMP
SceS000005032
GO:0006281 DNA repair P
NAS
HsaTOP2A
GO:0006333 chromatin assembly or disassembly P
IMP
SceS000005032
GO:0006974 response to DNA damage stimulus P
IDA
HsaTOP2A
GO:0007059 chromosome segregation P
IDA
MmuMGI:98790
IMP
HsaTOP2A
MmuMGI:98790
ISS
AthTOPII
GO:0007131 reciprocal meiotic recombination P
IMP
SceS000005032
GO:0008152 metabolic process P
IGI
MmuMGI:98790
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00010785
GO:0030261 chromosome condensation P
IMP
MmuMGI:98790
GO:0030263 apoptotic chromosome condensation P
IDA
HsaTOP2A
GO:0031055 chromatin remodeling at centromere P
IMP
SceS000005032
GO:0040016 embryonic cleavage P
IMP
MmuMGI:98790
GO:0043065 positive regulation of apoptosis P
IDA
HsaTOP2A
GO:0045070 positive regulation of viral genome
replication		 P
IMP
HsaTOP2A
GO:0045870 positive regulation of retroviral genome
replication		 P
IMP
HsaTOP2A
GO:0045944 positive regulation of transcription from RNA
polymerase II promoter		 P
IMP
MmuMGI:98790
GO:0048015 phosphoinositide-mediated signaling P
NAS
HsaTOP2A
GO:0051301 cell division P
IMP
CelWBGene00010785
GO:0070683 decatenation checkpoint P
IMP
SceS000005032

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_532

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga10991 ENSANGP00000022005
Anopheles gambiae (Aga) aga10992 ENSANGP00000027887
Ashbya gossypii (Ago) ago2910 AER410W
Arabidopsis thaliana (Ath) ath14711 At3g23890.1
Caenorhabditis elegans (Cel) cel12676 K12D12.1
(CE06184;
WBGene00010785)
Caenorhabditis elegans (Cel) cel21572 ZK1127.7
(CE42386;
WBGene00022854)
Candida glabrata (Cgl) cgl3234 CAGL0J05610g
Cryptococcus neoformans (Cne) cne2120 181.m08113
Dictyostelium discoideum (Ddi) ddi12674 DDB0214907
Dictyostelium discoideum (Ddi) ddi12138 DDB0231510
Debaryomyces hansenii (Dha) dha3346 DEHA0E02343g
Drosophila melanogaster (Dme) dme2993 CG10223-PA
(FBgn0003732)
Danio rerio (Dre) dre9013 ENSDARP00000040440
Danio rerio (Dre) dre9792 ENSDARP00000041111
Danio rerio (Dre) dre9014 ENSDARP00000041752
Danio rerio (Dre) dre9790 ENSDARP00000044355
Danio rerio (Dre) dre9791 ENSDARP00000045795
(LOC569877)		 Q1LUT2
Danio rerio (Dre) dre9012 ENSDARP00000050142
Escherichia coli (Eco) eco2928 16130926
Encephalitozoon cuniculi (Ecu) ecu750 19074112
Takifugu rubripes (Fru) fru31291 SINFRUP00000139068
Takifugu rubripes (Fru) fru25003 SINFRUP00000141662
Takifugu rubripes (Fru) fru25002 SINFRUP00000141672
Takifugu rubripes (Fru) fru31292 SINFRUP00000141991
Takifugu rubripes (Fru) fru31290 SINFRUP00000176443
Gallus gallus (Gga) gga13939 ENSGALP00000006238
Gallus gallus (Gga) gga13938 ENSGALP00000006239
(TOP2A)
Gallus gallus (Gga) gga9971 ENSGALP00000018410
(TOP2B)
Homo sapiens (Hsa) hsa22179 ENSP00000264331
(TOP2B)		 Q02880-1
Homo sapiens (Hsa) hsa13614 ENSP00000269577
(TOP2A)		 A6NDM0
Homo sapiens (Hsa) hsa13616 ENSP00000342944
(TOP2A)		 C9JGD1
Homo sapiens (Hsa) hsa13615 ENSP00000350217
(TOP2A)		 C9J5P2
Kluyveromyces lactis (Kla) kla1817 KLLA0C13838g
Mus musculus (Mmu) mmu7685 ENSMUSP00000017629
(MGI:98791)		 Q64511
Mus musculus (Mmu) mmu4748 ENSMUSP00000068896
(MGI:98790)		 Q01320
Mus musculus (Mmu) mmu4747 ENSMUSP00000074395
Neurospora crassa (Ncr) ncr6157 NCU06338.2
Oryza sativa (Osa) osa25581 3850.m00159
Plasmodium falciparum (Pfa) pfa1767 PF14_0316
Rattus norvegicus (Rno) rno6053 ENSRNOP00000040257
(RGD:62048)
Rattus norvegicus (Rno) rno6054 ENSRNOP00000045833
(RGD:62048)		 P41516
Saccharomyces cerevisiae (Sce) sce5201 YNL088W
(S000005032)
Schizosaccharomyces pombe (Spo) spo4205 SPBC1A4.03c P08096
Yarrowia lipolytica (Yli) yli3709 YALI0D23969g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000228 nuclear chromosome C
NAS
SpoSPBC1A4.03c
GO:0000793 condensed chromosome C
IDA
MmuMGI:98790
GO:0000795 synaptonemal complex C
IDA
SceS000005032
GO:0005625 soluble fraction C
IDA
DmeFBgn0003732
GO:0005626 insoluble fraction C
IDA
DmeFBgn0003732
GO:0005634 nucleus C
IDA
AthAt3g23890
DmeFBgn0003732
MmuMGI:98791
MGI:98790
SceS000005032
SpoSPBC1A4.03c
ISO
MmuMGI:98790
NAS
DmeFBgn0003732
GO:0005694 chromosome C
IDA
DmeFBgn0003732
GO:0005730 nucleolus C
IDA
MmuMGI:98790
GO:0005737 cytoplasm C
IDA
DmeFBgn0003732
GO:0005739 mitochondrion C
IDA
SceS000005032
GO:0008623 chromatin accessibility complex C
IDA
DmeFBgn0003732
GO:0009330 DNA topoisomerase complex (ATP-hydrolyzing) C
ISO
MmuMGI:98790
ISS
AthAt3g23890
GO:0000182 rDNA binding F
IDA
DmeFBgn0003732
GO:0000400 four-way junction DNA binding F
IDA
DmeFBgn0003732
GO:0003677 DNA binding F
IDA
DmeFBgn0003732
ISS
AthAt3g23890
GO:0003682 chromatin binding F
ISO
MmuMGI:98790
GO:0003696 satellite DNA binding F
IDA
DmeFBgn0003732
GO:0003729 mRNA binding F
IDA
DmeFBgn0003732
GO:0003916 DNA topoisomerase activity F
ISO
MmuMGI:98790
ISS
AthAt3g23890
GO:0003918 DNA topoisomerase (ATP-hydrolyzing)
activity		 F
IDA
DmeFBgn0003732
MmuMGI:98790
SceS000005032
SpoSPBC1A4.03c
IGI
MmuMGI:98790
SpoSPBC1A4.03c
IMP
SpoSPBC1A4.03c
ISO
MmuMGI:98790
ISS
AthAt3g23890
NAS
DmeFBgn0003732
GO:0005524 ATP binding F
IC
SpoSPBC1A4.03c
ISO
MmuMGI:98790
ISS
AthAt3g23890
GO:0008094 DNA-dependent ATPase activity F
ISS
AthAt3g23890
GO:0043565 sequence-specific DNA binding F
ISO
MmuMGI:98790
GO:0043566 structure-specific DNA binding F
ISO
MmuMGI:98790
GO:0000003 reproduction P
IMP
CelWBGene00022854
GO:0000019 regulation of mitotic recombination P
IMP
SceS000005032
GO:0000712 resolution of meiotic recombination
intermediates		 P
IMP
SpoSPBC1A4.03c
GO:0000819 sister chromatid segregation P
IDA
DmeFBgn0003732
GO:0000910 cytokinesis P
IMP
CelWBGene00022854
WBGene00010785
GO:0001764 neuron migration P
IMP
MmuMGI:98791
GO:0006259 DNA metabolic process P
ISS
AthAt3g23890
GO:0006265 DNA topological change P
IDA
DmeFBgn0003732
MmuMGI:98790
SceS000005032
SpoSPBC1A4.03c
IGI
SpoSPBC1A4.03c
IMP
SpoSPBC1A4.03c
ISO
MmuMGI:98790
ISS
AthAt3g23890
GO:0006271 DNA strand elongation involved in DNA
replication		 P
IMP
SceS000005032
ISS
SpoSPBC1A4.03c
GO:0006325 chromatin organization P
IGI
SpoSPBC1A4.03c
GO:0006333 chromatin assembly or disassembly P
IMP
SceS000005032
GO:0006342 chromatin silencing P
IDA
DmeFBgn0003732
GO:0006406 mRNA export from nucleus P
IMP
SpoSPBC1A4.03c
GO:0007052 mitotic spindle organization P
IMP
DmeFBgn0003732
GO:0007059 chromosome segregation P
IDA
MmuMGI:98790
IMP
MmuMGI:98790
ISS
AthAt3g23890
GO:0007067 mitosis P
TAS
DmeFBgn0003732
GO:0007076 mitotic chromosome condensation P
IMP
DmeFBgn0003732
SpoSPBC1A4.03c
GO:0007126 meiosis P
TAS
DmeFBgn0003732
GO:0007131 reciprocal meiotic recombination P
IMP
SceS000005032
GO:0007409 axonogenesis P
IMP
MmuMGI:98791
GO:0008152 metabolic process P
IGI
MmuMGI:98790
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00010785
WBGene00022854
GO:0016246 RNA interference P
IMP
CelWBGene00022854
GO:0030261 chromosome condensation P
IMP
MmuMGI:98790
GO:0030900 forebrain development P
IMP
MmuMGI:98791
GO:0031055 chromatin remodeling at centromere P
IMP
SceS000005032
GO:0040016 embryonic cleavage P
IMP
MmuMGI:98790
GO:0042790 transcription of nuclear rRNA large RNA polymerase
I transcript		 P
IGI
SpoSPBC1A4.03c
GO:0045944 positive regulation of transcription from RNA
polymerase II promoter		 P
IMP
MmuMGI:98790
GO:0051301 cell division P
IMP
CelWBGene00022854
WBGene00010785
GO:0051310 metaphase plate congression P
IDA
DmeFBgn0003732
GO:0070683 decatenation checkpoint P
IMP
SceS000005032

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC1A4.03c
(P08096)		 YNL088W
(S000005032)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000228 nuclear chromosome C
NAS
SpoSPBC1A4.03c
GO:0000795 synaptonemal complex C
IDA
SceS000005032
GO:0005634 nucleus C
IDA
SceS000005032
SpoSPBC1A4.03c
GO:0005739 mitochondrion C
IDA
SceS000005032
GO:0003918 DNA topoisomerase (ATP-hydrolyzing)
activity		 F
IDA
SceS000005032
SpoSPBC1A4.03c
IGI
SpoSPBC1A4.03c
IMP
SpoSPBC1A4.03c
GO:0005524 ATP binding F
IC
SpoSPBC1A4.03c
GO:0000019 regulation of mitotic recombination P
IMP
SceS000005032
GO:0000712 resolution of meiotic recombination
intermediates		 P
IMP
SpoSPBC1A4.03c
GO:0006265 DNA topological change P
IDA
SceS000005032
SpoSPBC1A4.03c
IGI
SpoSPBC1A4.03c
IMP
SpoSPBC1A4.03c
GO:0006271 DNA strand elongation involved in DNA
replication		 P
IMP
SceS000005032
ISS
SpoSPBC1A4.03c
GO:0006325 chromatin organization P
IGI
SpoSPBC1A4.03c
GO:0006333 chromatin assembly or disassembly P
IMP
SceS000005032
GO:0006406 mRNA export from nucleus P
IMP
SpoSPBC1A4.03c
GO:0007076 mitotic chromosome condensation P
IMP
SpoSPBC1A4.03c
GO:0007131 reciprocal meiotic recombination P
IMP
SceS000005032
GO:0031055 chromatin remodeling at centromere P
IMP
SceS000005032
GO:0042790 transcription of nuclear rRNA large RNA polymerase
I transcript		 P
IGI
SpoSPBC1A4.03c
GO:0070683 decatenation checkpoint P
IMP
SceS000005032

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s.khadayate@ucl.ac.uk