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Search term: YNL116W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name DMA2
SGD link S000005060
Alternative ID YNL116W
Description Protein involved in ubiquitination; plays a role in regulating spindle position and orientation; functionally redundant with Dma1p; orthologous to human RNF8 protein, also has sequence similarity to human Chfr
Synonyms YNL116W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3872 -CDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING FOG: FHA domain

Species KOG link NCBI link UniProt link
Caenorhabditis elegans (Cel) CE17187_1 GI:17541530
Drosophila melanogaster (Dme) 7289492_1 GI:7289492
Homo sapiens (Hsa) Hs4504867 GI:4504867 O76064
Saccharomyces cerevisiae (Sce) YDR200c
(S000002608)		 GI:6320406 Q03944
Saccharomyces cerevisiae (Sce) YHR115c
(S000001157)		 GI:6321907 P38823
Saccharomyces cerevisiae (Sce) YLR238w
(S000004228)		 GI:6323267 Q06001
Saccharomyces cerevisiae (Sce) YNL116w
(S000005060)		 GI:6324213 P53924
Schizosaccharomyces pombe (Spo) SPAC17G8.10c GI:19114645 Q10322
Schizosaccharomyces pombe (Spo) SPBC3H7.13 GI:19112554 O74388


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000005060
S000002608
S000001157
GO:0005783 endoplasmic reticulum C
IDA
SceS000004228
ISS
SpoSPBC3H7.13
GO:0005789 endoplasmic reticulum membrane C
IDA
SceS000002608
GO:0005816 spindle pole body C
IDA
SpoSPAC17G8.10c
SPBC3H7.13
GO:0005829 cytosol C
IDA
SpoSPAC17G8.10c
SPBC3H7.13
GO:0016020 membrane C
NAS
SpoSPBC3H7.13
GO:0032153 cell division site C
IDA
SpoSPBC3H7.13
SPAC17G8.10c
GO:0051286 cell tip C
IDA
SpoSPBC3H7.13
GO:0003674 molecular_function F
ND
SceS000004228
S000002608
SpoSPBC3H7.13
GO:0004842 ubiquitin-protein ligase activity F
IDA
SceS000001157
S000005060
ISS
SpoSPAC17G8.10c
GO:0008270 zinc ion binding F
ISS
SpoSPAC17G8.10c
GO:0000132 establishment of mitotic spindle
orientation		 P
IGI
SceS000001157
S000005060
GO:0000321 re-entry into mitotic cell cycle after pheromone
arrest		 P
IGI
SceS000004228
S000002608
GO:0000921 septin ring assembly P
IGI
SceS000001157
S000005060
GO:0006623 protein targeting to vacuole P
IMP
SceS000002608
GO:0007094 mitotic cell cycle spindle assembly
checkpoint		 P
IGI
SceS000001157
S000005060
IMP
SpoSPAC17G8.10c
GO:0008150 biological_process P
ND
SpoSPBC3H7.13
GO:0016567 protein ubiquitination P
ISS
SpoSPAC17G8.10c
GO:0031030 negative regulation of septation initiation
signaling		 P
TAS
SpoSPAC17G8.10c
GO:0051865 protein autoubiquitination P
IDA
SceS000001157
S000005060

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
104103

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) DMA1
(S000001157)		 GI:6321907 P38823
Saccharomyces cerevisiae (Sce) DMA2
(S000005060)		 GI:6324213 P53924
Kluyveromyces lactis (Kla) KLLA0F23892g GI:50312225
Eremothecium gossypii (Ego) AGOS_ACR267C GI:45185953


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000005060
S000001157
GO:0004842 ubiquitin-protein ligase activity F
IDA
SceS000001157
S000005060
GO:0000132 establishment of mitotic spindle
orientation		 P
IGI
SceS000001157
S000005060
GO:0000921 septin ring assembly P
IGI
SceS000001157
S000005060
GO:0007094 mitotic cell cycle spindle assembly
checkpoint		 P
IGI
SceS000001157
S000005060
GO:0051865 protein autoubiquitination P
IDA
SceS000001157
S000005060

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_10429

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago1314 ACR267C
Candida glabrata (Cgl) cgl4250 CAGL0L03960g
Cryptococcus neoformans (Cne) cne4296 177.m03053
Cryptococcus neoformans (Cne) cne4297 177.m03350
Cryptococcus neoformans (Cne) cne4298 177.m03351
Debaryomyces hansenii (Dha) dha368 DEHA0A08294g
Kluyveromyces lactis (Kla) kla5144 KLLA0F23892g
Neurospora crassa (Ncr) ncr6094 NCU06269.2
Saccharomyces cerevisiae (Sce) sce5232 YNL116W
(S000005060)
Schizosaccharomyces pombe (Spo) spo2699 SPAC17G8.10c Q10322
Yarrowia lipolytica (Yli) yli6125 YALI0F18634g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000005060
GO:0005816 spindle pole body C
IDA
SpoSPAC17G8.10c
GO:0005829 cytosol C
IDA
SpoSPAC17G8.10c
GO:0032153 cell division site C
IDA
SpoSPAC17G8.10c
GO:0004842 ubiquitin-protein ligase activity F
IDA
SceS000005060
ISS
SpoSPAC17G8.10c
GO:0008270 zinc ion binding F
ISS
SpoSPAC17G8.10c
GO:0000132 establishment of mitotic spindle
orientation		 P
IGI
SceS000005060
GO:0000921 septin ring assembly P
IGI
SceS000005060
GO:0007094 mitotic cell cycle spindle assembly
checkpoint		 P
IGI
SceS000005060
IMP
SpoSPAC17G8.10c
GO:0016567 protein ubiquitination P
ISS
SpoSPAC17G8.10c
GO:0031030 negative regulation of septation initiation
signaling		 P
TAS
SpoSPAC17G8.10c
GO:0051865 protein autoubiquitination P
IDA
SceS000005060

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC17G8.10c
(Q10322)		 YNL116W
(S000005060)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000005060
GO:0005816 spindle pole body C
IDA
SpoSPAC17G8.10c
GO:0005829 cytosol C
IDA
SpoSPAC17G8.10c
GO:0032153 cell division site C
IDA
SpoSPAC17G8.10c
GO:0004842 ubiquitin-protein ligase activity F
IDA
SceS000005060
ISS
SpoSPAC17G8.10c
GO:0008270 zinc ion binding F
ISS
SpoSPAC17G8.10c
GO:0000132 establishment of mitotic spindle
orientation		 P
IGI
SceS000005060
GO:0000921 septin ring assembly P
IGI
SceS000005060
GO:0007094 mitotic cell cycle spindle assembly
checkpoint		 P
IGI
SceS000005060
IMP
SpoSPAC17G8.10c
GO:0016567 protein ubiquitination P
ISS
SpoSPAC17G8.10c
GO:0031030 negative regulation of septation initiation
signaling		 P
TAS
SpoSPAC17G8.10c
GO:0051865 protein autoubiquitination P
IDA
SceS000005060

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