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Search term: YNL119W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name NCS2
SGD link S000005063
Alternative ID YNL119W
Description Protein required for thiolation of the uridine at the wobble position of Lys(UUU) and Glu(UUC) tRNAs; has a role in urmylation and in invasive and pseudohyphal growth; inhibits replication of Brome mosaic virus in S. cerevisiae
Synonyms YNL119W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2594 ACD-YP-

KOGs classification KOGs description
POORLY CHARACTERIZED Uncharacterized conserved protein

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At4g35910 GI:7486391
Caenorhabditis elegans (Cel) CE23690
(WBGene00009256)		 GI:17560354 Q19906
Drosophila melanogaster (Dme) 7298594
(FBgn0032793)		 GI:20129633
Saccharomyces cerevisiae (Sce) YNL119w
(S000005063)		 GI:6324209 P53923
Schizosaccharomyces pombe (Spo) SPBC19C2.13c GI:19112490 Q9UUC7


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0002144 cytosolic tRNA wobble base thiouridylase
complex		 C
IDA
SpoSPBC19C2.13c
GO:0005575 cellular_component C
ND
AthAt4g35910
DmeFBgn0032793
GO:0005634 nucleus C
IDA
SpoSPBC19C2.13c
GO:0005737 cytoplasm C
IDA
SceS000005063
GO:0005829 cytosol C
TAS
SpoSPBC19C2.13c
GO:0003674 molecular_function F
ND
AthAt4g35910
SceS000005063
GO:0005515 protein binding F
IPI
SpoSPBC19C2.13c
GO:0001403 invasive growth in response to glucose
limitation		 P
IMP
SceS000005063
GO:0002098 tRNA wobble uridine modification P
IMP
SceS000005063
GO:0002143 wobble position uridine thiolation P
IMP
SceS000005063
IPI
SpoSPBC19C2.13c
GO:0007124 pseudohyphal growth P
IMP
SceS000005063
GO:0008150 biological_process P
ND
AthAt4g35910
DmeFBgn0032793
GO:0032447 protein urmylation P
IMP
SceS000005063
ISS
SpoSPBC19C2.13c
GO:0034227 tRNA thio-modification P
IMP
SceS000005063

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
40113

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) NCS2
(S000005063)		 GI:6324209 P53923
Kluyveromyces lactis (Kla) KLLA0F24002g GI:50312235
Eremothecium gossypii (Ego) AGOS_ACR271C GI:45185957


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000005063
GO:0003674 molecular_function F
ND
SceS000005063
GO:0001403 invasive growth in response to glucose
limitation		 P
IMP
SceS000005063
GO:0002098 tRNA wobble uridine modification P
IMP
SceS000005063
GO:0002143 wobble position uridine thiolation P
IMP
SceS000005063
GO:0007124 pseudohyphal growth P
IMP
SceS000005063
GO:0032447 protein urmylation P
IMP
SceS000005063
GO:0034227 tRNA thio-modification P
IMP
SceS000005063

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_15305

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago1318 ACR271C
Candida glabrata (Cgl) cgl4253 CAGL0L04026g
Debaryomyces hansenii (Dha) dha5356 DEHA0F21824g
Kluyveromyces lactis (Kla) kla5149 KLLA0F24002g
Neurospora crassa (Ncr) ncr7673 NCU07877.2
Saccharomyces cerevisiae (Sce) sce5235 YNL119W
(S000005063)
Schizosaccharomyces pombe (Spo) spo440 SPBC19C2.13c Q9UUC7
Yarrowia lipolytica (Yli) yli1159 YALI0B10263g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0002144 cytosolic tRNA wobble base thiouridylase
complex		 C
IDA
SpoSPBC19C2.13c
GO:0005634 nucleus C
IDA
SpoSPBC19C2.13c
GO:0005737 cytoplasm C
IDA
SceS000005063
GO:0005829 cytosol C
TAS
SpoSPBC19C2.13c
GO:0003674 molecular_function F
ND
SceS000005063
GO:0005515 protein binding F
IPI
SpoSPBC19C2.13c
GO:0001403 invasive growth in response to glucose
limitation		 P
IMP
SceS000005063
GO:0002098 tRNA wobble uridine modification P
IMP
SceS000005063
GO:0002143 wobble position uridine thiolation P
IMP
SceS000005063
IPI
SpoSPBC19C2.13c
GO:0007124 pseudohyphal growth P
IMP
SceS000005063
GO:0032447 protein urmylation P
IMP
SceS000005063
ISS
SpoSPBC19C2.13c
GO:0034227 tRNA thio-modification P
IMP
SceS000005063

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC19C2.13c
(Q9UUC7)		 YNL119W
(S000005063)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0002144 cytosolic tRNA wobble base thiouridylase
complex		 C
IDA
SpoSPBC19C2.13c
GO:0005634 nucleus C
IDA
SpoSPBC19C2.13c
GO:0005737 cytoplasm C
IDA
SceS000005063
GO:0005829 cytosol C
TAS
SpoSPBC19C2.13c
GO:0003674 molecular_function F
ND
SceS000005063
GO:0005515 protein binding F
IPI
SpoSPBC19C2.13c
GO:0001403 invasive growth in response to glucose
limitation		 P
IMP
SceS000005063
GO:0002098 tRNA wobble uridine modification P
IMP
SceS000005063
GO:0002143 wobble position uridine thiolation P
IMP
SceS000005063
IPI
SpoSPBC19C2.13c
GO:0007124 pseudohyphal growth P
IMP
SceS000005063
GO:0032447 protein urmylation P
IMP
SceS000005063
ISS
SpoSPBC19C2.13c
GO:0034227 tRNA thio-modification P
IMP
SceS000005063

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