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Search term: YNL123W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name NMA111
SGD link S000005067
Alternative ID YNL123W
Description Serine protease and general molecular chaperone; involved in response to heat stress and promotion of apoptosis; may contribute to lipid homeostasis; sequence similarity to the mammalian Omi/HtrA2 family of serine proteases
Synonyms YNL123W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1421 A---YP-

KOGs classification KOGs description
POORLY CHARACTERIZED Predicted signaling-associated protein (contains a PDZ domain)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g03380 GI:18396530
Arabidopsis thaliana (Ath) At3g03390 GI:15228543
Saccharomyces cerevisiae (Sce) YNL123w
(S000005067)		 GI:6324206 P53920
Schizosaccharomyces pombe (Spo) SPAC23G3.12c GI:19114024 Q9P7S1
Schizosaccharomyces pombe (Spo) SPBC1685.05 GI:19112001 O74325


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000005067
SpoSPAC23G3.12c
GO:0005829 cytosol C
IDA
SpoSPBC1685.05
GO:0009507 chloroplast C
IDA
AthAt3g03380
GO:0004252 serine-type endopeptidase activity F
ISS
SpoSPAC23G3.12c
SPBC1685.05
GO:0008233 peptidase activity F
IDA
AthAt3g03380
GO:0008236 serine-type peptidase activity F
IDA
SceS000005067
ISS
AthAt3g03380
SceS000005067
GO:0006508 proteolysis P
ISS
AthAt3g03380
SpoSPBC1685.05
GO:0006629 lipid metabolic process P
ISS
SpoSPAC23G3.12c
GO:0006915 apoptosis P
IMP
SceS000005067
ISS
SceS000005067
GO:0010205 photoinhibition P
IMP
AthAt3g03380
GO:0030163 protein catabolic process P
IMP
SceS000005067
GO:0034605 cellular response to heat P
IMP
SceS000005067
GO:0044255 cellular lipid metabolic process P
IMP
SceS000005067
IPI
SceS000005067
GO:0051603 proteolysis involved in cellular protein catabolic
process		 P
NAS
SpoSPAC23G3.12c
SPBC1685.05

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
2076

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) SPAC23G3.12c GI:19114024 Q9P7S1
Saccharomyces cerevisiae (Sce) NMA111
(S000005067)		 GI:6324206 P53920
Kluyveromyces lactis (Kla) KLLA0F24090g GI:50312243
Eremothecium gossypii (Ego) AGOS_ABR134C GI:45185364
Magnaporthe grisea (Mgr) MGG_01824 GI:145613179
Neurospora crassa (Ncr) NCU05200.1 GI:32408151
Arabidopsis thaliana (Ath) DegP7 GI:30678834
Oryza sativa (Osa) Os02g0712000 GI:115448251


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000005067
SpoSPAC23G3.12c
GO:0009507 chloroplast C
IDA
AthDegP7
GO:0004252 serine-type endopeptidase activity F
ISS
SpoSPAC23G3.12c
GO:0008233 peptidase activity F
IDA
AthDegP7
GO:0008236 serine-type peptidase activity F
IDA
SceS000005067
ISS
AthDegP7
SceS000005067
GO:0006508 proteolysis P
ISS
AthDegP7
GO:0006629 lipid metabolic process P
ISS
SpoSPAC23G3.12c
GO:0006915 apoptosis P
IMP
SceS000005067
ISS
SceS000005067
GO:0010205 photoinhibition P
IMP
AthDegP7
GO:0030163 protein catabolic process P
IMP
SceS000005067
GO:0034605 cellular response to heat P
IMP
SceS000005067
GO:0044255 cellular lipid metabolic process P
IMP
SceS000005067
IPI
SceS000005067
GO:0051603 proteolysis involved in cellular protein catabolic
process		 P
NAS
SpoSPAC23G3.12c

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_11571

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago726 ABR134C
Arabidopsis thaliana (Ath) ath12362 At3g03380.1
Candida glabrata (Cgl) cgl4256 CAGL0L04092g
Debaryomyces hansenii (Dha) dha5369 DEHA0F22110g
Kluyveromyces lactis (Kla) kla5153 KLLA0F24090g
Neurospora crassa (Ncr) ncr5047 NCU05200.2
Oryza sativa (Osa) osa6009 2434.m00135
Saccharomyces cerevisiae (Sce) sce5239 YNL123W
(S000005067)
Schizosaccharomyces pombe (Spo) spo4138 SPAC23G3.12c Q9P7S1
Yarrowia lipolytica (Yli) yli6645 YALI0F31603g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000005067
SpoSPAC23G3.12c
GO:0009507 chloroplast C
IDA
AthAt3g03380
GO:0004252 serine-type endopeptidase activity F
ISS
SpoSPAC23G3.12c
GO:0008233 peptidase activity F
IDA
AthAt3g03380
GO:0008236 serine-type peptidase activity F
IDA
SceS000005067
ISS
AthAt3g03380
SceS000005067
GO:0006508 proteolysis P
ISS
AthAt3g03380
GO:0006629 lipid metabolic process P
ISS
SpoSPAC23G3.12c
GO:0006915 apoptosis P
IMP
SceS000005067
ISS
SceS000005067
GO:0010205 photoinhibition P
IMP
AthAt3g03380
GO:0030163 protein catabolic process P
IMP
SceS000005067
GO:0034605 cellular response to heat P
IMP
SceS000005067
GO:0044255 cellular lipid metabolic process P
IMP
SceS000005067
IPI
SceS000005067
GO:0051603 proteolysis involved in cellular protein catabolic
process		 P
NAS
SpoSPAC23G3.12c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC1685.05
(O74325)		 YNL123W
(S000005067)
SPAC23G3.12c
(Q9P7S1)		 YNL123W
(S000005067)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000005067
SpoSPAC23G3.12c
GO:0005829 cytosol C
IDA
SpoSPBC1685.05
GO:0004252 serine-type endopeptidase activity F
ISS
SpoSPAC23G3.12c
SPBC1685.05
GO:0008236 serine-type peptidase activity F
IDA
SceS000005067
ISS
SceS000005067
GO:0006508 proteolysis P
ISS
SpoSPBC1685.05
GO:0006629 lipid metabolic process P
ISS
SpoSPAC23G3.12c
GO:0006915 apoptosis P
IMP
SceS000005067
ISS
SceS000005067
GO:0030163 protein catabolic process P
IMP
SceS000005067
GO:0034605 cellular response to heat P
IMP
SceS000005067
GO:0044255 cellular lipid metabolic process P
IMP
SceS000005067
IPI
SceS000005067
GO:0051603 proteolysis involved in cellular protein catabolic
process		 P
NAS
SpoSPAC23G3.12c
SPBC1685.05

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