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Search term: YNL124W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name NAF1
SGD link S000005068
Alternative ID YNL124W
Description RNA-binding protein required for the assembly of box H/ACA snoRNPs and thus for pre-rRNA processing, forms a complex with Shq1p and interacts with H/ACA snoRNP components Nhp2p and Cbf5p; similar to Gar1p
Synonyms YNL124W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2236 ACDHYP-

KOGs classification KOGs description
POORLY CHARACTERIZED Uncharacterized conserved protein

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g03530 GI:15218825
Caenorhabditis elegans (Cel) CE05728
(WBGene00009132)		 GI:17540000 Q19788
Drosophila melanogaster (Dme) 7298473 GI:7298473
Homo sapiens (Hsa) Hs19923911 GI:19923911
Saccharomyces cerevisiae (Sce) YNL124w
(S000005068)		 GI:6324205 P53919
Schizosaccharomyces pombe (Spo) SPBC30D10.15 GI:19113062 O14360


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000005068
SpoSPBC30D10.15
GO:0005635 nuclear envelope C
IDA
SpoSPBC30D10.15
GO:0005654 nucleoplasm C
IDA
SceS000005068
ISS
SpoSPBC30D10.15
GO:0003723 RNA binding F
IPI
SceS000005068
ISS
SpoSPBC30D10.15
GO:0000003 reproduction P
IMP
CelWBGene00009132
GO:0000493 box H/ACA snoRNP assembly P
IMP
SceS000005068
IPI
SceS000005068
ISS
SpoSPBC30D10.15
GO:0001522 pseudouridine synthesis P
RCA
SceS000005068
GO:0006364 rRNA processing P
IC
SpoSPBC30D10.15
GO:0006898 receptor-mediated endocytosis P
IMP
CelWBGene00009132
GO:0008150 biological_process P
ND
AthAt1g03530
GO:0009451 RNA modification P
RCA
SceS000005068
GO:0019915 lipid storage P
IMP
CelWBGene00009132
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00009132
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00009132
GO:0042274 ribosomal small subunit biogenesis P
RCA
SceS000005068

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
90923

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) NAF1 GI:193083157
Pan troglodytes (Ptr) NAF1 GI:114596667
Canis familiaris (Cfa) NAF1 GI:73978364
Mus musculus (Mmu) Gm2027 GI:149263216
Rattus norvegicus (Rno) Naf1 GI:67078478
Gallus gallus (Gga) NAF1 GI:118089819
Drosophila melanogaster (Dme) CG10341
(FBgn0032701)		 GI:19921494
Anopheles gambiae (Aga) AgaP_AGAP011831 GI:158300871
Saccharomyces cerevisiae (Sce) NAF1
(S000005068)		 GI:6324205 P53919
Kluyveromyces lactis (Kla) KLLA0F24178g GI:50312251
Eremothecium gossypii (Ego) AGOS_ABR138C GI:45185368
Magnaporthe grisea (Mgr) MGG_10116 GI:39969011
Neurospora crassa (Ncr) NCU04455.1 GI:32406390
Arabidopsis thaliana (Ath) NAF1 GI:145335038
Oryza sativa (Osa) Os05g0502800 GI:115464753


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000005068
GO:0005654 nucleoplasm C
IDA
SceS000005068
GO:0005732 small nucleolar ribonucleoprotein
complex		 C
IDA
HsaNAF1
GO:0003723 RNA binding F
IDA
HsaNAF1
IPI
SceS000005068
GO:0005515 protein binding F
IPI
HsaNAF1
GO:0000493 box H/ACA snoRNP assembly P
IMP
SceS000005068
IPI
SceS000005068
GO:0001522 pseudouridine synthesis P
RCA
SceS000005068
GO:0009451 RNA modification P
RCA
SceS000005068
GO:0042254 ribosome biogenesis P
IDA
HsaNAF1
GO:0042274 ribosomal small subunit biogenesis P
RCA
SceS000005068

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_4750

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago730 ABR138C
Arabidopsis thaliana (Ath) ath292 At1g03530.1
Candida glabrata (Cgl) cgl4257 CAGL0L04114g
Cryptococcus neoformans (Cne) cne2967 167.m03261
Debaryomyces hansenii (Dha) dha5374 DEHA0F22220g
Drosophila melanogaster (Dme) dme2858 CG10341-PA
(FBgn0032701)
Danio rerio (Dre) dre18165 ENSDARP00000016898
Takifugu rubripes (Fru) fru13422 SINFRUP00000174282
Gallus gallus (Gga) gga17243 ENSGALP00000015443
(NAF1)
Homo sapiens (Hsa) hsa24803 ENSP00000274054
(NAF1)		 Q96HR8
Kluyveromyces lactis (Kla) kla5157 KLLA0F24178g
Mus musculus (Mmu) mmu26037 ENSMUSP00000015051
(MGI:2682306)		 Q3UMQ8
Neurospora crassa (Ncr) ncr4326 NCU04455.2
Oryza sativa (Osa) osa48749 5826.m00207
Rattus norvegicus (Rno) rno12315 ENSRNOP00000030093
(RGD:1306802)
Rattus norvegicus (Rno) rno12314 ENSRNOP00000031163
(RGD:1306802)		 Q52KK4
Saccharomyces cerevisiae (Sce) sce5240 YNL124W
(S000005068)
Schizosaccharomyces pombe (Spo) spo3443 SPBC30D10.15 O14360
Yarrowia lipolytica (Yli) yli1157 YALI0B10219g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:2682306
GO:0005634 nucleus C
IDA
SceS000005068
SpoSPBC30D10.15
GO:0005635 nuclear envelope C
IDA
SpoSPBC30D10.15
GO:0005654 nucleoplasm C
IDA
SceS000005068
ISS
SpoSPBC30D10.15
GO:0003674 molecular_function F
ND
MmuMGI:2682306
GO:0003723 RNA binding F
IPI
SceS000005068
ISS
SpoSPBC30D10.15
GO:0000493 box H/ACA snoRNP assembly P
IMP
SceS000005068
IPI
SceS000005068
ISS
SpoSPBC30D10.15
GO:0001522 pseudouridine synthesis P
RCA
SceS000005068
GO:0006364 rRNA processing P
IC
SpoSPBC30D10.15
GO:0008150 biological_process P
ND
AthAt1g03530
MmuMGI:2682306
GO:0009451 RNA modification P
RCA
SceS000005068
GO:0042274 ribosomal small subunit biogenesis P
RCA
SceS000005068

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC30D10.15
(O14360)		 YNL124W
(S000005068)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000005068
SpoSPBC30D10.15
GO:0005635 nuclear envelope C
IDA
SpoSPBC30D10.15
GO:0005654 nucleoplasm C
IDA
SceS000005068
ISS
SpoSPBC30D10.15
GO:0003723 RNA binding F
IPI
SceS000005068
ISS
SpoSPBC30D10.15
GO:0000493 box H/ACA snoRNP assembly P
IMP
SceS000005068
IPI
SceS000005068
ISS
SpoSPBC30D10.15
GO:0001522 pseudouridine synthesis P
RCA
SceS000005068
GO:0006364 rRNA processing P
IC
SpoSPBC30D10.15
GO:0009451 RNA modification P
RCA
SceS000005068
GO:0042274 ribosomal small subunit biogenesis P
RCA
SceS000005068

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GO info in one table:

s.khadayate@ucl.ac.uk