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Search term: YNL178W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name RPS3
SGD link S000005122
Alternative ID YNL178W
Description Protein component of the small (40S) ribosomal subunit, has apurinic/apyrimidinic (AP) endonuclease activity; essential for viability; has similarity to E. coli S3 and rat S3 ribosomal proteins
Synonyms YNL178W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3181 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING 40S ribosomal protein S3

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g31610 GI:15225107
Arabidopsis thaliana (Ath) At3g53870 GI:15232352
Arabidopsis thaliana (Ath) At5g35530 GI:15238533
Caenorhabditis elegans (Cel) CE01810
(WBGene00004472)		 GI:17554770 P48152
Drosophila melanogaster (Dme) 7300992
(FBgn0002622)		 GI:17136324
Homo sapiens (Hsa) Hs14781627 GI:14781627
Homo sapiens (Hsa) Hs15718687
(RPS3)		 GI:15718687 P23396
Homo sapiens (Hsa) Hs17448831 GI:17448831
Homo sapiens (Hsa) Hs18580587 GI:18580587
Homo sapiens (Hsa) Hs22059034 GI:22059034
Homo sapiens (Hsa) Hs22060075 GI:22060075
Saccharomyces cerevisiae (Sce) YNL178w
(S000005122)		 GI:6324151 P05750
Schizosaccharomyces pombe (Spo) SPBC16G5.14c GI:19113555 O60128
Encephalitozoon cuniculi (Ecu) ECU09g1250 GI:19173244


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
DmeFBgn0002622
HsaRPS3
NAS
DmeFBgn0002622
GO:0005730 nucleolus C
IDA
AthAt5g35530
GO:0005737 cytoplasm C
IDA
HsaRPS3
NAS
DmeFBgn0002622
GO:0005773 vacuole C
IDA
AthAt2g31610
GO:0005811 lipid particle C
IDA
DmeFBgn0002622
GO:0005829 cytosol C
EXP
HsaRPS3
IDA
HsaRPS3
SpoSPBC16G5.14c
GO:0005840 ribosome C
NAS
DmeFBgn0002622
GO:0005875 microtubule associated complex C
IDA
DmeFBgn0002622
GO:0005886 plasma membrane C
IDA
AthAt2g31610
GO:0009507 chloroplast C
IDA
AthAt2g31610
GO:0016020 membrane C
IDA
AthAt3g53870
At2g31610
At5g35530
GO:0016363 nuclear matrix C
IDA
DmeFBgn0002622
GO:0022626 cytosolic ribosome C
IDA
AthAt3g53870
At2g31610
At5g35530
GO:0022627 cytosolic small ribosomal subunit C
IDA
AthAt3g53870
At2g31610
At5g35530
HsaRPS3
SceS000005122
ISS
AthAt3g53870
At5g35530
At2g31610
DmeFBgn0002622
SpoSPBC16G5.14c
NAS
DmeFBgn0002622
GO:0030529 ribonucleoprotein complex C
IDA
HsaRPS3
GO:0030686 90S preribosome C
IDA
SceS000005122
GO:0030688 preribosome, small subunit precursor C
IDA
SceS000005122
GO:0032587 ruffle membrane C
IDA
HsaRPS3
GO:0003684 damaged DNA binding F
IDA
HsaRPS3
GO:0003729 mRNA binding F
IDA
HsaRPS3
GO:0003735 structural constituent of ribosome F
IDA
HsaRPS3
SceS000005122
ISS
AthAt3g53870
At2g31610
At5g35530
DmeFBgn0002622
SpoSPBC16G5.14c
NAS
DmeFBgn0002622
HsaRPS3
GO:0003906 DNA-(apurinic or apyrimidinic site) lyase
activity		 F
IDA
DmeFBgn0002622
HsaRPS3
SceS000005122
NAS
DmeFBgn0002622
GO:0004519 endonuclease activity F
IMP
HsaRPS3
GO:0005515 protein binding F
IPI
HsaRPS3
GO:0008534 oxidized purine base lesion DNA N-glycosylase
activity		 F
IDA
DmeFBgn0002622
GO:0019901 protein kinase binding F
IPI
HsaRPS3
GO:0051059 NF-kappaB binding F
IPI
HsaRPS3
GO:0051536 iron-sulfur cluster binding F
NAS
HsaRPS3
GO:0000003 reproduction P
IMP
CelWBGene00004472
GO:0002119 nematode larval development P
IMP
CelWBGene00004472
GO:0006281 DNA repair P
IGI
DmeFBgn0002622
NAS
DmeFBgn0002622
GO:0006407 rRNA export from nucleus P
IMP
SceS000005122
GO:0006412 translation P
IC
HsaRPS3
SceS000005122
ISS
AthAt2g31610
At3g53870
At5g35530
DmeFBgn0002622
SpoSPBC16G5.14c
NAS
DmeFBgn0002622
HsaRPS3
GO:0006413 translational initiation P
NAS
HsaRPS3
GO:0006414 translational elongation P
EXP
HsaRPS3
GO:0006917 induction of apoptosis P
IDA
HsaRPS3
GO:0006919 activation of caspase activity P
IDA
HsaRPS3
GO:0006974 response to DNA damage stimulus P
IEP
HsaRPS3
IMP
DmeFBgn0002622
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00004472
GO:0009628 response to abiotic stimulus P
IEP
AthAt2g31610
GO:0009651 response to salt stress P
IEP
AthAt3g53870
At5g35530
At2g31610
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00004472
GO:0018996 molting cycle, collagen and cuticulin-based
cuticle		 P
IMP
CelWBGene00004472
GO:0019915 lipid storage P
IMP
CelWBGene00004472
GO:0032088 negative regulation of NF-kappaB transcription
factor activity		 P
IMP
HsaRPS3
GO:0040007 growth P
IMP
CelWBGene00004472
GO:0043524 negative regulation of neuron apoptosis P
IMP
DmeFBgn0002622
GO:0045738 negative regulation of DNA repair P
IMP
HsaRPS3

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
779

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) RPS3 GI:15718687 P23396
Pan troglodytes (Ptr) RPS3 GI:114590687
Canis familiaris (Cfa) RPS3 GI:57102362
Mus musculus (Mmu) Rps3
(MGI:1350917)		 GI:6755372 O89068
Rattus norvegicus (Rno) Rps3
(RGD:619888)		 GI:57164151
Gallus gallus (Gga) RPS3 GI:71895095
Drosophila melanogaster (Dme) RpS3
(FBgn0002622)		 GI:17136324
Anopheles gambiae (Aga) AgaP_AGAP001910 GI:118793920
Caenorhabditis elegans (Cel) rps-3
(CE01810;
WBGene00004472)		 GI:17554770 P48152
Schizosaccharomyces pombe (Spo) rps3
(SPBC16G5.14c)		 GI:19113555 O60128
Saccharomyces cerevisiae (Sce) RPS3
(S000005122)		 GI:6324151 P05750
Kluyveromyces lactis (Kla) KLLA0D08305g GI:50306913
Eremothecium gossypii (Ego) AGOS_ABL138W GI:45185092
Magnaporthe grisea (Mgr) MGG_05673 GI:145615557
Neurospora crassa (Ncr) NCU00489.1 GI:32403924
Arabidopsis thaliana (Ath) AT5G35530 GI:15238533
Arabidopsis thaliana (Ath) AT2G31610 GI:15225107
Arabidopsis thaliana (Ath) AT3G53870 GI:15232352
Oryza sativa (Osa) Os07g0608500 GI:115473289
Oryza sativa (Osa) Os03g0577000 GI:115453877
Plasmodium falciparum (Pfa) PF14_0627 GI:124810210


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
DmeFBgn0002622
HsaRPS3
NAS
DmeFBgn0002622
GO:0005730 nucleolus C
IDA
AthAt5g35530
GO:0005737 cytoplasm C
IDA
HsaRPS3
MmuMGI:1350917
NAS
DmeFBgn0002622
GO:0005773 vacuole C
IDA
AthAt2g31610
GO:0005811 lipid particle C
IDA
DmeFBgn0002622
GO:0005829 cytosol C
EXP
HsaRPS3
IDA
HsaRPS3
SpoSPBC16G5.14c
GO:0005840 ribosome C
NAS
DmeFBgn0002622
GO:0005875 microtubule associated complex C
IDA
DmeFBgn0002622
GO:0005886 plasma membrane C
IDA
AthAt2g31610
GO:0009507 chloroplast C
IDA
AthAt2g31610
GO:0012505 endomembrane system C
ISO
MmuMGI:1350917
GO:0016020 membrane C
IDA
AthAt3g53870
At2g31610
At5g35530
GO:0016363 nuclear matrix C
IDA
DmeFBgn0002622
GO:0022626 cytosolic ribosome C
IDA
AthAt3g53870
At2g31610
At5g35530
GO:0022627 cytosolic small ribosomal subunit C
IDA
AthAt3g53870
At2g31610
At5g35530
HsaRPS3
SceS000005122
ISO
MmuMGI:1350917
ISS
AthAt3g53870
At5g35530
At2g31610
DmeFBgn0002622
PfaPF14_0627
SpoSPBC16G5.14c
NAS
DmeFBgn0002622
GO:0030425 dendrite C
ISO
MmuMGI:1350917
GO:0030529 ribonucleoprotein complex C
IDA
HsaRPS3
GO:0030686 90S preribosome C
IDA
SceS000005122
GO:0030688 preribosome, small subunit precursor C
IDA
SceS000005122
GO:0032587 ruffle membrane C
IDA
HsaRPS3
GO:0003684 damaged DNA binding F
IDA
HsaRPS3
GO:0003729 mRNA binding F
IDA
HsaRPS3
GO:0003735 structural constituent of ribosome F
IDA
HsaRPS3
SceS000005122
ISS
AthAt3g53870
At2g31610
At5g35530
DmeFBgn0002622
SpoSPBC16G5.14c
NAS
DmeFBgn0002622
HsaRPS3
GO:0003906 DNA-(apurinic or apyrimidinic site) lyase
activity		 F
IDA
DmeFBgn0002622
HsaRPS3
SceS000005122
NAS
DmeFBgn0002622
GO:0004519 endonuclease activity F
IMP
HsaRPS3
GO:0005515 protein binding F
IPI
HsaRPS3
GO:0008534 oxidized purine base lesion DNA N-glycosylase
activity		 F
IDA
DmeFBgn0002622
GO:0019901 protein kinase binding F
IPI
HsaRPS3
GO:0051059 NF-kappaB binding F
IPI
HsaRPS3
GO:0051536 iron-sulfur cluster binding F
NAS
HsaRPS3
GO:0000003 reproduction P
IMP
CelWBGene00004472
GO:0002119 nematode larval development P
IMP
CelWBGene00004472
GO:0006281 DNA repair P
IGI
DmeFBgn0002622
NAS
DmeFBgn0002622
GO:0006407 rRNA export from nucleus P
IMP
SceS000005122
GO:0006412 translation P
IC
HsaRPS3
SceS000005122
ISS
AthAt2g31610
At3g53870
At5g35530
DmeFBgn0002622
SpoSPBC16G5.14c
NAS
DmeFBgn0002622
HsaRPS3
GO:0006413 translational initiation P
NAS
HsaRPS3
GO:0006414 translational elongation P
EXP
HsaRPS3
GO:0006917 induction of apoptosis P
IDA
HsaRPS3
GO:0006919 activation of caspase activity P
IDA
HsaRPS3
GO:0006974 response to DNA damage stimulus P
IEP
HsaRPS3
IMP
DmeFBgn0002622
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00004472
GO:0009628 response to abiotic stimulus P
IEP
AthAt2g31610
GO:0009651 response to salt stress P
IEP
AthAt3g53870
At5g35530
At2g31610
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00004472
GO:0018996 molting cycle, collagen and cuticulin-based
cuticle		 P
IMP
CelWBGene00004472
GO:0019915 lipid storage P
IMP
CelWBGene00004472
GO:0032088 negative regulation of NF-kappaB transcription
factor activity		 P
IMP
HsaRPS3
GO:0040007 growth P
IMP
CelWBGene00004472
GO:0043524 negative regulation of neuron apoptosis P
IMP
DmeFBgn0002622
GO:0045738 negative regulation of DNA repair P
IMP
HsaRPS3

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1360

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga4009 ENSANGP00000020844
Ashbya gossypii (Ago) ago454 ABL138W
Arabidopsis thaliana (Ath) ath10161 At2g31610.1
Arabidopsis thaliana (Ath) ath16744 At3g53870.1
Arabidopsis thaliana (Ath) ath25323 At5g35530.1
Caenorhabditis elegans (Cel) cel2486 C23G10.3
(CE01810;
WBGene00004472)
Candida glabrata (Cgl) cgl3485 CAGL0J11220g
Cryptococcus neoformans (Cne) cne1915 181.m07884
Dictyostelium discoideum (Ddi) ddi13525 DDB0201667
Debaryomyces hansenii (Dha) dha6776 DEHA0G24178g
Drosophila melanogaster (Dme) dme14007 CG6779-PA
(FBgn0002622)
Danio rerio (Dre) dre25074 ENSDARP00000032823
Encephalitozoon cuniculi (Ecu) ecu1395 19173244
Takifugu rubripes (Fru) fru12679 SINFRUP00000162445
Gallus gallus (Gga) gga3517 ENSGALP00000027953
(RPS3)
Homo sapiens (Hsa) hsa6248 ENSP00000278572
(RPS3)		 P23396
Kluyveromyces lactis (Kla) kla2431 KLLA0D08305g
Mus musculus (Mmu) mmu24491 ENSMUSP00000032998
(MGI:1350917)		 P62908
Neurospora crassa (Ncr) ncr475 NCU00489.2
Oryza sativa (Osa) osa5106 2346.m00144
Oryza sativa (Osa) osa5163 2346.m00199
Oryza sativa (Osa) osa15255 3029.m00153
Oryza sativa (Osa) osa61498 6440.m00134
Oryza sativa (Osa) osa85240 8373.m00142
Plasmodium falciparum (Pfa) pfa1418 PF14_0627
Rattus norvegicus (Rno) rno2388 ENSRNOP00000023935
(RGD:619888)		 P62909
Saccharomyces cerevisiae (Sce) sce5299 YNL178W
(S000005122)
Schizosaccharomyces pombe (Spo) spo3743 SPBC16G5.14c O60128
Yarrowia lipolytica (Yli) yli4843 YALI0E23694g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
DmeFBgn0002622
NAS
DmeFBgn0002622
GO:0005730 nucleolus C
IDA
AthAt5g35530
GO:0005737 cytoplasm C
IDA
MmuMGI:1350917
NAS
DmeFBgn0002622
GO:0005773 vacuole C
IDA
AthAt2g31610
GO:0005811 lipid particle C
IDA
DmeFBgn0002622
GO:0005829 cytosol C
IDA
SpoSPBC16G5.14c
GO:0005840 ribosome C
NAS
DmeFBgn0002622
GO:0005875 microtubule associated complex C
IDA
DmeFBgn0002622
GO:0005886 plasma membrane C
IDA
AthAt2g31610
GO:0009507 chloroplast C
IDA
AthAt2g31610
GO:0012505 endomembrane system C
ISO
MmuMGI:1350917
GO:0016020 membrane C
IDA
AthAt3g53870
At2g31610
At5g35530
GO:0016363 nuclear matrix C
IDA
DmeFBgn0002622
GO:0022626 cytosolic ribosome C
IDA
AthAt3g53870
At2g31610
At5g35530
GO:0022627 cytosolic small ribosomal subunit C
IDA
AthAt3g53870
At2g31610
At5g35530
SceS000005122
ISO
MmuMGI:1350917
ISS
AthAt3g53870
At5g35530
At2g31610
DmeFBgn0002622
PfaPF14_0627
SpoSPBC16G5.14c
NAS
DmeFBgn0002622
GO:0030425 dendrite C
ISO
MmuMGI:1350917
GO:0030686 90S preribosome C
IDA
SceS000005122
GO:0030688 preribosome, small subunit precursor C
IDA
SceS000005122
GO:0003735 structural constituent of ribosome F
IDA
SceS000005122
ISS
AthAt3g53870
At2g31610
At5g35530
DmeFBgn0002622
SpoSPBC16G5.14c
NAS
DmeFBgn0002622
GO:0003906 DNA-(apurinic or apyrimidinic site) lyase
activity		 F
IDA
DmeFBgn0002622
SceS000005122
NAS
DmeFBgn0002622
GO:0008534 oxidized purine base lesion DNA N-glycosylase
activity		 F
IDA
DmeFBgn0002622
GO:0000003 reproduction P
IMP
CelWBGene00004472
GO:0002119 nematode larval development P
IMP
CelWBGene00004472
GO:0006281 DNA repair P
IGI
DmeFBgn0002622
NAS
DmeFBgn0002622
GO:0006407 rRNA export from nucleus P
IMP
SceS000005122
GO:0006412 translation P
IC
SceS000005122
ISS
AthAt2g31610
At3g53870
At5g35530
DmeFBgn0002622
SpoSPBC16G5.14c
NAS
DmeFBgn0002622
GO:0006974 response to DNA damage stimulus P
IMP
DmeFBgn0002622
GO:0008340 determination of adult lifespan P
IMP
CelWBGene00004472
GO:0009628 response to abiotic stimulus P
IEP
AthAt2g31610
GO:0009651 response to salt stress P
IEP
AthAt3g53870
At5g35530
At2g31610
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00004472
GO:0018996 molting cycle, collagen and cuticulin-based
cuticle		 P
IMP
CelWBGene00004472
GO:0019915 lipid storage P
IMP
CelWBGene00004472
GO:0040007 growth P
IMP
CelWBGene00004472
GO:0043524 negative regulation of neuron apoptosis P
IMP
DmeFBgn0002622

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC16G5.14c
(O60128)		 YNL178W
(S000005122)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005829 cytosol C
IDA
SpoSPBC16G5.14c
GO:0022627 cytosolic small ribosomal subunit C
IDA
SceS000005122
ISS
SpoSPBC16G5.14c
GO:0030686 90S preribosome C
IDA
SceS000005122
GO:0030688 preribosome, small subunit precursor C
IDA
SceS000005122
GO:0003735 structural constituent of ribosome F
IDA
SceS000005122
ISS
SpoSPBC16G5.14c
GO:0003906 DNA-(apurinic or apyrimidinic site) lyase
activity		 F
IDA
SceS000005122
GO:0006407 rRNA export from nucleus P
IMP
SceS000005122
GO:0006412 translation P
IC
SceS000005122
ISS
SpoSPBC16G5.14c

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Query species:

Include wild-cards:   

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GO info in one table:

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