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Search term: YNL218W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name MGS1
SGD link S000005162
Alternative ID YNL218W
Description Protein with DNA-dependent ATPase and ssDNA annealing activities involved in maintenance of genome; interacts functionally with DNA polymerase delta; homolog of human Werner helicase interacting protein (WHIP)
Synonyms YNL218W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2028 A--HYP-

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING ATPase related to the helicase subunit of the Holliday junction resolvase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g24290 GI:15221721
Homo sapiens (Hsa) Hs18426902
(WRNIP1)		 GI:18426902 Q9NRJ6
Homo sapiens (Hsa) Hs18426904 GI:18426904 Q9NRJ6
Saccharomyces cerevisiae (Sce) YNL218w
(S000005162)		 GI:6324111 P40151
Schizosaccharomyces pombe (Spo) SPAC26H5.02c GI:19115361 O13984


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
HsaWRNIP1
SceS000005162
ISS
HsaWRNIP1
SpoSPAC26H5.02c
GO:0005737 cytoplasm C
IDA
SceS000005162
GO:0048471 perinuclear region of cytoplasm C
IDA
HsaWRNIP1
GO:0000739 DNA strand annealing activity F
IDA
SceS000005162
GO:0005515 protein binding F
IPI
HsaWRNIP1
GO:0005524 ATP binding F
ISS
AthAt1g24290
GO:0008047 enzyme activator activity F
IDA
SceS000005162
GO:0016887 ATPase activity F
IMP
HsaWRNIP1
GO:0043130 ubiquitin binding F
ISS
SceS000005162
GO:0043142 single-stranded DNA-dependent ATPase
activity		 F
IDA
SceS000005162
ISS
SpoSPAC26H5.02c
GO:0000731 DNA synthesis involved in DNA repair P
IDA
HsaWRNIP1
ISS
SpoSPAC26H5.02c
GO:0006200 ATP catabolic process P
NAS
SpoSPAC26H5.02c
GO:0006282 regulation of DNA repair P
IGI
SceS000005162
GO:0030174 regulation of DNA-dependent DNA replication
initiation		 P
IDA
HsaWRNIP1
GO:0033567 DNA replication, Okazaki fragment
processing		 P
IDA
SceS000005162
ISS
SpoSPAC26H5.02c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
10592

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) WRNIP1 GI:18426902 Q9NRJ6
Pan troglodytes (Ptr) WRNIP1 GI:114605194
Mus musculus (Mmu) Wrnip1
(MGI:1926153)		 GI:31981384 Q91XU0
Rattus norvegicus (Rno) Wrnip1
(RGD:628836)		 GI:27229310
Gallus gallus (Gga) WRNIP1 GI:118086469
Schizosaccharomyces pombe (Spo) SPAC26H5.02c GI:19115361 O13984
Saccharomyces cerevisiae (Sce) MGS1
(S000005162)		 GI:6324111 P40151
Kluyveromyces lactis (Kla) KLLA0D19360g GI:50307855
Eremothecium gossypii (Ego) AGOS_ABL183W GI:45185047
Neurospora crassa (Ncr) NCU08706.1 GI:32420759
Arabidopsis thaliana (Ath) AT1G24290 GI:15221721


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
HsaWRNIP1
MmuMGI:1926153
SceS000005162
ISS
HsaWRNIP1
SpoSPAC26H5.02c
GO:0005737 cytoplasm C
IDA
SceS000005162
GO:0048471 perinuclear region of cytoplasm C
IDA
HsaWRNIP1
GO:0000739 DNA strand annealing activity F
IDA
SceS000005162
GO:0005515 protein binding F
IPI
HsaWRNIP1
MmuMGI:1926153
GO:0005524 ATP binding F
ISS
AthAt1g24290
GO:0008047 enzyme activator activity F
IDA
SceS000005162
GO:0016887 ATPase activity F
IMP
HsaWRNIP1
GO:0043130 ubiquitin binding F
ISS
SceS000005162
GO:0043142 single-stranded DNA-dependent ATPase
activity		 F
IDA
SceS000005162
ISS
SpoSPAC26H5.02c
GO:0000731 DNA synthesis involved in DNA repair P
IDA
HsaWRNIP1
ISS
SpoSPAC26H5.02c
GO:0006200 ATP catabolic process P
NAS
SpoSPAC26H5.02c
GO:0006282 regulation of DNA repair P
IGI
SceS000005162
GO:0008150 biological_process P
ND
MmuMGI:1926153
GO:0030174 regulation of DNA-dependent DNA replication
initiation		 P
IDA
HsaWRNIP1
GO:0033567 DNA replication, Okazaki fragment
processing		 P
IDA
SceS000005162
ISS
SpoSPAC26H5.02c

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1797

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga8788 ENSANGP00000017992
Ashbya gossypii (Ago) ago409 ABL183W
Arabidopsis thaliana (Ath) ath2621 At1g24290.1
Candida glabrata (Cgl) cgl3738 CAGL0K04983g
Dictyostelium discoideum (Ddi) ddi3586 DDB0168762
Debaryomyces hansenii (Dha) dha6479 DEHA0G17402g
Danio rerio (Dre) dre27916 ENSDARP00000010591
(zgc:85976)		 Q6NW46
Escherichia coli (Eco) eco862 16128859
Encephalitozoon cuniculi (Ecu) ecu67 19073988
Takifugu rubripes (Fru) fru27048 SINFRUP00000127060
Gallus gallus (Gga) gga10547 ENSGALP00000020937
(WRNIP1)		 Q800M2
Gallus gallus (Gga) gga10546 ENSGALP00000020938
(WRNIP1)
Homo sapiens (Hsa) hsa26356 ENSP00000244490
Homo sapiens (Hsa) hsa26357 ENSP00000339533
Kluyveromyces lactis (Kla) kla2920 KLLA0D19360g
Mus musculus (Mmu) mmu6786 ENSMUSP00000021832
(MGI:1926153)		 Q91XU0-1
Neurospora crassa (Ncr) ncr8485 NCU08706.2
Plasmodium falciparum (Pfa) pfa1075 PF11_0131
Rattus norvegicus (Rno) rno13252 ENSRNOP00000023332
(RGD:628836)		 Q8CG07
Saccharomyces cerevisiae (Sce) sce5339 YNL218W
(S000005162)
Schizosaccharomyces pombe (Spo) spo1161 SPAC26H5.02c O13984
Yarrowia lipolytica (Yli) yli1919 YALI0C05038g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
MmuMGI:1926153
SceS000005162
ISS
SpoSPAC26H5.02c
GO:0005737 cytoplasm C
IDA
SceS000005162
GO:0000739 DNA strand annealing activity F
IDA
SceS000005162
GO:0005515 protein binding F
IPI
MmuMGI:1926153
GO:0005524 ATP binding F
ISS
AthAt1g24290
GO:0008047 enzyme activator activity F
IDA
SceS000005162
GO:0043130 ubiquitin binding F
ISS
SceS000005162
GO:0043142 single-stranded DNA-dependent ATPase
activity		 F
IDA
SceS000005162
ISS
SpoSPAC26H5.02c
GO:0000731 DNA synthesis involved in DNA repair P
ISS
SpoSPAC26H5.02c
GO:0006200 ATP catabolic process P
NAS
SpoSPAC26H5.02c
GO:0006282 regulation of DNA repair P
IGI
SceS000005162
GO:0008150 biological_process P
ND
MmuMGI:1926153
GO:0033567 DNA replication, Okazaki fragment
processing		 P
IDA
SceS000005162
ISS
SpoSPAC26H5.02c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC26H5.02c
(O13984)		 YNL218W
(S000005162)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000005162
ISS
SpoSPAC26H5.02c
GO:0005737 cytoplasm C
IDA
SceS000005162
GO:0000739 DNA strand annealing activity F
IDA
SceS000005162
GO:0008047 enzyme activator activity F
IDA
SceS000005162
GO:0043130 ubiquitin binding F
ISS
SceS000005162
GO:0043142 single-stranded DNA-dependent ATPase
activity		 F
IDA
SceS000005162
ISS
SpoSPAC26H5.02c
GO:0000731 DNA synthesis involved in DNA repair P
ISS
SpoSPAC26H5.02c
GO:0006200 ATP catabolic process P
NAS
SpoSPAC26H5.02c
GO:0006282 regulation of DNA repair P
IGI
SceS000005162
GO:0033567 DNA replication, Okazaki fragment
processing		 P
IDA
SceS000005162
ISS
SpoSPAC26H5.02c

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s.khadayate@ucl.ac.uk