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Search term: YNL224C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SQS1
SGD link S000005168
Alternative ID YNL224C
Description Stimulates the ATPase and helicase activities of Prp43p; acts with Prp43p to stimulate 18s rRNA maturation by Nob1p; overexpression antagonizes the suppression of splicing defects by spp382 mutants; component of pre-ribosomal particles
Synonyms YNL224C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0154 ACDHYP-

KOGs classification KOGs description
POORLY CHARACTERIZED RNA-binding protein RBM5 and related proteins, contain G-patch and RRM domains

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g52350 GI:15231192
Arabidopsis thaliana (Ath) At3g54230 GI:15232464
Arabidopsis thaliana (Ath) At5g08540 GI:9759348
Caenorhabditis elegans (Cel) CE25984
(WBGene00020346)		 GI:17508947 Q9GYS7
Caenorhabditis elegans (Cel) CE26949 GI:17508949 Q9GYS7
Caenorhabditis elegans (Cel) CE28712
(WBGene00013224)		 GI:17543634 Q95Q15
Caenorhabditis elegans (Cel) CE28713 GI:17543636 Q95Q15
Drosophila melanogaster (Dme) 7296104 GI:7296104
Drosophila melanogaster (Dme) 7296106 GI:7296106 Q9VPY4
Drosophila melanogaster (Dme) 7303092 GI:19922310 A1Z9Z1
Homo sapiens (Hsa) Hs11034829 GI:11034829
Homo sapiens (Hsa) Hs17488041 GI:17488041
Homo sapiens (Hsa) Hs20127479
(RBM10)		 GI:20127479 P98175
Homo sapiens (Hsa) Hs20562455_2 GI:20562455
Homo sapiens (Hsa) Hs22041759_2 GI:22041759
Homo sapiens (Hsa) Hs22053488 GI:22053488
Homo sapiens (Hsa) Hs5032031
(RBM5)		 GI:5032031 Q9UKY8
Homo sapiens (Hsa) Hs5032033
(RBM6)		 GI:5032033 P78332
Homo sapiens (Hsa) Hs8922313
(GPATCH2)		 GI:8922313 Q6PIX0
Homo sapiens (Hsa) Hs8922326 GI:8922326
Homo sapiens (Hsa) Hs8923619 GI:8923619
Saccharomyces cerevisiae (Sce) YNL224c
(S000005168)		 GI:6324105 P53866
Schizosaccharomyces pombe (Spo) SPAC2G11.04 GI:19113996 Q09806
Schizosaccharomyces pombe (Spo) SPAC57A7.13 GI:19114280 P87143
Schizosaccharomyces pombe (Spo) SPBC30B4.02c GI:19112319 O74363
Schizosaccharomyces pombe (Spo) SPCC1442.13c GI:19075827 O94585
Arabidopsis thaliana (Ath) At3g52350 GI:15231192
Arabidopsis thaliana (Ath) At3g54230 GI:15232464
Arabidopsis thaliana (Ath) At5g08540 GI:9759348
Caenorhabditis elegans (Cel) CE25984
(WBGene00020346)		 GI:17508947 Q9GYS7
Caenorhabditis elegans (Cel) CE26949 GI:17508949 Q9GYS7
Caenorhabditis elegans (Cel) CE28712
(WBGene00013224)		 GI:17543634 Q95Q15
Caenorhabditis elegans (Cel) CE28713 GI:17543636 Q95Q15
Drosophila melanogaster (Dme) 7296104 GI:7296104
Drosophila melanogaster (Dme) 7296106 GI:7296106 Q9VPY4
Drosophila melanogaster (Dme) 7303092 GI:19922310 A1Z9Z1
Homo sapiens (Hsa) Hs11034829 GI:11034829
Homo sapiens (Hsa) Hs17488041 GI:17488041
Homo sapiens (Hsa) Hs20127479
(RBM10)		 GI:20127479 P98175
Homo sapiens (Hsa) Hs20562455_2 GI:20562455
Homo sapiens (Hsa) Hs22041759_2 GI:22041759
Homo sapiens (Hsa) Hs22053488 GI:22053488
Homo sapiens (Hsa) Hs5032031
(RBM5)		 GI:5032031 Q9UKY8
Homo sapiens (Hsa) Hs5032033
(RBM6)		 GI:5032033 P78332
Homo sapiens (Hsa) Hs8922313
(GPATCH2)		 GI:8922313 Q6PIX0
Homo sapiens (Hsa) Hs8922326 GI:8922326
Homo sapiens (Hsa) Hs8923619 GI:8923619
Saccharomyces cerevisiae (Sce) YNL224c
(S000005168)		 GI:6324105 P53866
Schizosaccharomyces pombe (Spo) SPAC2G11.04 GI:19113996 Q09806
Schizosaccharomyces pombe (Spo) SPAC57A7.13 GI:19114280 P87143
Schizosaccharomyces pombe (Spo) SPBC30B4.02c GI:19112319 O74363
Schizosaccharomyces pombe (Spo) SPCC1442.13c GI:19075827 O94585
Arabidopsis thaliana (Ath) At3g52350 GI:15231192
Arabidopsis thaliana (Ath) At3g54230 GI:15232464
Arabidopsis thaliana (Ath) At5g08540 GI:9759348
Caenorhabditis elegans (Cel) CE25984
(WBGene00020346)		 GI:17508947 Q9GYS7
Caenorhabditis elegans (Cel) CE26949 GI:17508949 Q9GYS7
Caenorhabditis elegans (Cel) CE28712
(WBGene00013224)		 GI:17543634 Q95Q15
Caenorhabditis elegans (Cel) CE28713 GI:17543636 Q95Q15
Drosophila melanogaster (Dme) 7296104 GI:7296104
Drosophila melanogaster (Dme) 7296106 GI:7296106 Q9VPY4
Drosophila melanogaster (Dme) 7303092 GI:19922310 A1Z9Z1
Homo sapiens (Hsa) Hs11034829 GI:11034829
Homo sapiens (Hsa) Hs17488041 GI:17488041
Homo sapiens (Hsa) Hs20127479
(RBM10)		 GI:20127479 P98175
Homo sapiens (Hsa) Hs20562455_2 GI:20562455
Homo sapiens (Hsa) Hs22041759_2 GI:22041759
Homo sapiens (Hsa) Hs22053488 GI:22053488
Homo sapiens (Hsa) Hs5032031
(RBM5)		 GI:5032031 Q9UKY8
Homo sapiens (Hsa) Hs5032033
(RBM6)		 GI:5032033 P78332
Homo sapiens (Hsa) Hs8922313
(GPATCH2)		 GI:8922313 Q6PIX0
Homo sapiens (Hsa) Hs8922326 GI:8922326
Homo sapiens (Hsa) Hs8923619 GI:8923619
Saccharomyces cerevisiae (Sce) YNL224c
(S000005168)		 GI:6324105 P53866
Schizosaccharomyces pombe (Spo) SPAC2G11.04 GI:19113996 Q09806
Schizosaccharomyces pombe (Spo) SPAC57A7.13 GI:19114280 P87143
Schizosaccharomyces pombe (Spo) SPBC30B4.02c GI:19112319 O74363
Schizosaccharomyces pombe (Spo) SPCC1442.13c GI:19075827 O94585


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005622 intracellular C
ISS
AthAt3g52350
GO:0005634 nucleus C
IDA
AthAt3g54230
HsaRBM5
RBM10
SceS000005168
SpoSPAC2G11.04
SPAC57A7.13
SPCC1442.13c
NAS
HsaRBM10
GO:0005681 spliceosomal complex C
TAS
HsaRBM5
GO:0005737 cytoplasm C
IDA
SceS000005168
SpoSPBC30B4.02c
GO:0005816 spindle pole body C
IDA
SpoSPCC1442.13c
GO:0005819 spindle C
IDA
SpoSPCC1442.13c
GO:0005829 cytosol C
IDA
SpoSPAC2G11.04
SPBC30B4.02c
GO:0009507 chloroplast C
IDA
AthAt5g08540
GO:0009535 chloroplast thylakoid membrane C
IDA
AthAt5g08540
GO:0009941 chloroplast envelope C
IDA
AthAt5g08540
GO:0016585 chromatin remodeling complex C
IDA
HsaRBM10
GO:0030686 90S preribosome C
IDA
SceS000005168
GO:0030687 preribosome, large subunit precursor C
IDA
SceS000005168
GO:0030688 preribosome, small subunit precursor C
IDA
SceS000005168
ISS
SpoSPBC30B4.02c
GO:0003674 molecular_function F
ND
AthAt5g08540
SceS000005168
SpoSPCC1442.13c
SPAC2G11.04
SPBC30B4.02c
GO:0003676 nucleic acid binding F
ISS
AthAt3g54230
At3g52350
GO:0003677 DNA binding F
TAS
HsaRBM6
RBM5
GO:0003723 RNA binding F
ISS
SpoSPAC57A7.13
NAS
HsaRBM10
TAS
HsaRBM5
GO:0003729 mRNA binding F
IDA
HsaRBM5
GO:0005515 protein binding F
IPI
HsaRBM5
GO:0008270 zinc ion binding F
ISS
SpoSPAC57A7.13
GO:0000003 reproduction P
IMP
CelWBGene00020346
GO:0000245 spliceosome assembly P
IDA
HsaRBM5
GO:0000381 regulation of alternative nuclear mRNA splicing,
via spliceosome		 P
IDA
HsaRBM5
GO:0000398 nuclear mRNA splicing, via spliceosome P
IGI
SceS000005168
IMP
AthAt3g54230
ISS
SpoSPBC30B4.02c
NAS
SpoSPAC57A7.13
GO:0006364 rRNA processing P
IGI
SceS000005168
GO:0006396 RNA processing P
TAS
HsaRBM6
RBM5
GO:0007126 meiosis P
IEP
SpoSPCC1442.13c
IMP
SpoSPCC1442.13c
GO:0008150 biological_process P
ND
AthAt5g08540
At3g52350
HsaRBM10
SpoSPAC2G11.04
GO:0008285 negative regulation of cell proliferation P
TAS
HsaRBM5
GO:0008380 RNA splicing P
EXP
HsaRBM5
GO:0030490 maturation of SSU-rRNA P
IGI
SceS000005168
ISS
SpoSPBC30B4.02c
GO:0032781 positive regulation of ATPase activity P
IDA
SceS000005168
IMP
SceS000005168
GO:0043065 positive regulation of apoptosis P
IDA
HsaRBM5
TAS
HsaRBM5
GO:0051096 positive regulation of helicase
activity		 P
IDA
SceS000005168
IMP
SceS000005168

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
40073

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) SQS1
(S000005168)		 GI:6324105 P53866
Kluyveromyces lactis (Kla) KLLA0D19558g GI:50307873


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000005168
GO:0005737 cytoplasm C
IDA
SceS000005168
GO:0030686 90S preribosome C
IDA
SceS000005168
GO:0030687 preribosome, large subunit precursor C
IDA
SceS000005168
GO:0030688 preribosome, small subunit precursor C
IDA
SceS000005168
GO:0003674 molecular_function F
ND
SceS000005168
GO:0000398 nuclear mRNA splicing, via spliceosome P
IGI
SceS000005168
GO:0006364 rRNA processing P
IGI
SceS000005168
GO:0030490 maturation of SSU-rRNA P
IGI
SceS000005168
GO:0032781 positive regulation of ATPase activity P
IDA
SceS000005168
IMP
SceS000005168
GO:0051096 positive regulation of helicase
activity		 P
IDA
SceS000005168
IMP
SceS000005168

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_11601

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago400 ABL192C
Candida glabrata (Cgl) cgl3310 CAGL0J07326g
Cryptococcus neoformans (Cne) cne5809 179.m00684
Debaryomyces hansenii (Dha) dha355 DEHA0A08008g
Kluyveromyces lactis (Kla) kla2929 KLLA0D19558g
Neurospora crassa (Ncr) ncr2365 NCU02434.2
Saccharomyces cerevisiae (Sce) sce5345 YNL224C
(S000005168)
Schizosaccharomyces pombe (Spo) spo2294 SPBC30B4.02c O74363
Yarrowia lipolytica (Yli) yli5815 YALI0F11253g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000005168
GO:0005737 cytoplasm C
IDA
SceS000005168
SpoSPBC30B4.02c
GO:0005829 cytosol C
IDA
SpoSPBC30B4.02c
GO:0030686 90S preribosome C
IDA
SceS000005168
GO:0030687 preribosome, large subunit precursor C
IDA
SceS000005168
GO:0030688 preribosome, small subunit precursor C
IDA
SceS000005168
ISS
SpoSPBC30B4.02c
GO:0003674 molecular_function F
ND
SceS000005168
SpoSPBC30B4.02c
GO:0000398 nuclear mRNA splicing, via spliceosome P
IGI
SceS000005168
ISS
SpoSPBC30B4.02c
GO:0006364 rRNA processing P
IGI
SceS000005168
GO:0030490 maturation of SSU-rRNA P
IGI
SceS000005168
ISS
SpoSPBC30B4.02c
GO:0032781 positive regulation of ATPase activity P
IDA
SceS000005168
IMP
SceS000005168
GO:0051096 positive regulation of helicase
activity		 P
IDA
SceS000005168
IMP
SceS000005168

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC30B4.02c
(O74363)		 YNL224C
(S000005168)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000005168
GO:0005737 cytoplasm C
IDA
SceS000005168
SpoSPBC30B4.02c
GO:0005829 cytosol C
IDA
SpoSPBC30B4.02c
GO:0030686 90S preribosome C
IDA
SceS000005168
GO:0030687 preribosome, large subunit precursor C
IDA
SceS000005168
GO:0030688 preribosome, small subunit precursor C
IDA
SceS000005168
ISS
SpoSPBC30B4.02c
GO:0003674 molecular_function F
ND
SceS000005168
SpoSPBC30B4.02c
GO:0000398 nuclear mRNA splicing, via spliceosome P
IGI
SceS000005168
ISS
SpoSPBC30B4.02c
GO:0006364 rRNA processing P
IGI
SceS000005168
GO:0030490 maturation of SSU-rRNA P
IGI
SceS000005168
ISS
SpoSPBC30B4.02c
GO:0032781 positive regulation of ATPase activity P
IDA
SceS000005168
IMP
SceS000005168
GO:0051096 positive regulation of helicase
activity		 P
IDA
SceS000005168
IMP
SceS000005168

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