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Search term: YNL227C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name JJJ1
SGD link S000005171
Alternative ID YNL227C
Description Co-chaperone that stimulates the ATPase activity of Ssa1p, required for a late step of ribosome biogenesis; associated with the cytosolic large ribosomal subunit; contains a J-domain; mutation causes defects in fluid-phase endocytosis
Synonyms YNL227C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0717 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Molecular chaperone (DnaJ superfamily)

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g74250 GI:15221189
Caenorhabditis elegans (Cel) CE16336
(WBGene00001035)		 GI:17554874 O62360
Drosophila melanogaster (Dme) 7291882 GI:7291882
Homo sapiens (Hsa) Hs22051523 GI:22051523
Saccharomyces cerevisiae (Sce) YNL227c
(S000005171)		 GI:6324103 P53863
Schizosaccharomyces pombe (Spo) SPAC6B12.08 GI:19114675 O14213
Arabidopsis thaliana (Ath) At1g74250 GI:15221189
Caenorhabditis elegans (Cel) CE16336
(WBGene00001035)		 GI:17554874 O62360
Drosophila melanogaster (Dme) 7291882 GI:7291882
Homo sapiens (Hsa) Hs22051523 GI:22051523
Saccharomyces cerevisiae (Sce) YNL227c
(S000005171)		 GI:6324103 P53863
Schizosaccharomyces pombe (Spo) SPAC6B12.08 GI:19114675 O14213


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000005171
GO:0005739 mitochondrion C
IDA
SceS000005171
GO:0005783 endoplasmic reticulum C
IDA
SpoSPAC6B12.08
GO:0005829 cytosol C
IDA
SceS000005171
GO:0022625 cytosolic large ribosomal subunit C
IDA
SceS000005171
GO:0001671 ATPase activator activity F
IDA
SceS000005171
GO:0030544 Hsp70 protein binding F
ISS
SpoSPAC6B12.08
GO:0043565 sequence-specific DNA binding F
RCA
SceS000005171
GO:0000003 reproduction P
IMP
CelWBGene00001035
GO:0006457 protein folding P
ISS
AthAt1g74250
GO:0006897 endocytosis P
IMP
SceS000005171
GO:0008361 regulation of cell size P
IMP
SceS000005171
GO:0042254 ribosome biogenesis P
ISS
SpoSPAC6B12.08
GO:0042273 ribosomal large subunit biogenesis P
IMP
SceS000005171
RCA
SceS000005171

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
6752

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) DNAJC21 GI:68077168
Pan troglodytes (Ptr) DNAJC21 GI:114600700
Canis familiaris (Cfa) DNAJC21 GI:73953860
Mus musculus (Mmu) Dnajc21
(MGI:1925371)		 GI:149266408 Q3URP7
Rattus norvegicus (Rno) Dnajc21 GI:109464496
Gallus gallus (Gga) DNAJC21 GI:118103712
Drosophila melanogaster (Dme) CG2790
(FBgn0027599)		 GI:24762799
Anopheles gambiae (Aga) AgaP_AGAP009943 GI:158298938
Caenorhabditis elegans (Cel) dnj-17
(CE16336;
WBGene00001035)		 GI:17554874 O62360
Saccharomyces cerevisiae (Sce) JJJ1
(S000005171)		 GI:6324103 P53863
Kluyveromyces lactis (Kla) KLLA0D19602g GI:50307877
Eremothecium gossypii (Ego) AGOS_ABL194C GI:45185036
Magnaporthe grisea (Mgr) MGG_03581 GI:39943002
Neurospora crassa (Ncr) NCU02432.1 GI:32421529
Arabidopsis thaliana (Ath) AT1G74250 GI:15221189
Oryza sativa (Osa) Os12g0502700 GI:115488688
Plasmodium falciparum (Pfa) PF10_0058 GI:124802036


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:1925371
GO:0005737 cytoplasm C
IDA
SceS000005171
GO:0005739 mitochondrion C
IDA
SceS000005171
GO:0005829 cytosol C
IDA
SceS000005171
GO:0005840 ribosome C
NAS
HsaDNAJC21
GO:0022625 cytosolic large ribosomal subunit C
IDA
SceS000005171
GO:0001671 ATPase activator activity F
IDA
SceS000005171
GO:0003674 molecular_function F
ND
HsaDNAJC21
MmuMGI:1925371
GO:0043565 sequence-specific DNA binding F
RCA
SceS000005171
GO:0000003 reproduction P
IMP
CelWBGene00001035
GO:0006457 protein folding P
ISS
AthAt1g74250
NAS
HsaDNAJC21
GO:0006897 endocytosis P
IMP
SceS000005171
GO:0008150 biological_process P
ND
MmuMGI:1925371
GO:0008361 regulation of cell size P
IMP
SceS000005171
GO:0042273 ribosomal large subunit biogenesis P
IMP
SceS000005171
RCA
SceS000005171

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1850

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga12232 ENSANGP00000013296
Ashbya gossypii (Ago) ago398 ABL194C
Arabidopsis thaliana (Ath) ath6734 At1g74250.1
Caenorhabditis elegans (Cel) cel14401 T03F6.2
(CE16336;
WBGene00001035)
Candida glabrata (Cgl) cgl3312 CAGL0J07370g
Dictyostelium discoideum (Ddi) ddi9343 DDB0187017
Debaryomyces hansenii (Dha) dha354 DEHA0A07986g
Drosophila melanogaster (Dme) dme7125 CG2790-PA
(FBgn0027599)
Danio rerio (Dre) dre2118 ENSDARP00000026006
Takifugu rubripes (Fru) fru18920 SINFRUP00000160487
Takifugu rubripes (Fru) fru18921 SINFRUP00000166076
Gallus gallus (Gga) gga28303 ENSGALP00000005341
Gallus gallus (Gga) gga28301 ENSGALP00000005342
(RYR3)
Gallus gallus (Gga) gga28302 ENSGALP00000005343
(DNAJC21)
Homo sapiens (Hsa) hsa25114 ENSP00000306289
(DNAJC21)		 Q5F1R6-3
Homo sapiens (Hsa) hsa25115 ENSP00000343728
(DNAJC21)		 Q5F1R6-1
Kluyveromyces lactis (Kla) kla2931 KLLA0D19602g
Mus musculus (Mmu) mmu8772 ENSMUSP00000055555
(MGI:1925371)		 Q3URP7
Mus musculus (Mmu) mmu8773 ENSMUSP00000079656
(MGI:1925371)		 Q3USP3
Neurospora crassa (Ncr) ncr2363 NCU02432.2
Oryza sativa (Osa) osa68792 6918.m00101
Oryza sativa (Osa) osa67795 7003.m00101
Plasmodium falciparum (Pfa) pfa280 PF10_0058
Rattus norvegicus (Rno) rno15642 ENSRNOP00000024218
(RGD:621729)		 Q5RJL8
Saccharomyces cerevisiae (Sce) sce5348 YNL227C
(S000005171)
Schizosaccharomyces pombe (Spo) spo3635 SPAC6B12.08 O14213
Yarrowia lipolytica (Yli) yli1378 YALI0B15312g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:1925371
GO:0005737 cytoplasm C
IDA
SceS000005171
GO:0005739 mitochondrion C
IDA
SceS000005171
GO:0005783 endoplasmic reticulum C
IDA
SpoSPAC6B12.08
GO:0005829 cytosol C
IDA
SceS000005171
GO:0022625 cytosolic large ribosomal subunit C
IDA
SceS000005171
GO:0001671 ATPase activator activity F
IDA
SceS000005171
GO:0003674 molecular_function F
ND
MmuMGI:1925371
GO:0030544 Hsp70 protein binding F
ISS
SpoSPAC6B12.08
GO:0043565 sequence-specific DNA binding F
RCA
SceS000005171
GO:0000003 reproduction P
IMP
CelWBGene00001035
GO:0006457 protein folding P
ISS
AthAt1g74250
GO:0006897 endocytosis P
IMP
SceS000005171
GO:0008150 biological_process P
ND
MmuMGI:1925371
GO:0008361 regulation of cell size P
IMP
SceS000005171
GO:0042254 ribosome biogenesis P
ISS
SpoSPAC6B12.08
GO:0042273 ribosomal large subunit biogenesis P
IMP
SceS000005171
RCA
SceS000005171

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC6B12.08
(O14213)		 YNL227C
(S000005171)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000005171
GO:0005739 mitochondrion C
IDA
SceS000005171
GO:0005783 endoplasmic reticulum C
IDA
SpoSPAC6B12.08
GO:0005829 cytosol C
IDA
SceS000005171
GO:0022625 cytosolic large ribosomal subunit C
IDA
SceS000005171
GO:0001671 ATPase activator activity F
IDA
SceS000005171
GO:0030544 Hsp70 protein binding F
ISS
SpoSPAC6B12.08
GO:0043565 sequence-specific DNA binding F
RCA
SceS000005171
GO:0006897 endocytosis P
IMP
SceS000005171
GO:0008361 regulation of cell size P
IMP
SceS000005171
GO:0042254 ribosome biogenesis P
ISS
SpoSPAC6B12.08
GO:0042273 ribosomal large subunit biogenesis P
IMP
SceS000005171
RCA
SceS000005171

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