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Search term: YNL239W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name LAP3
SGD link S000005183
Alternative ID YNL239W
Description Cysteine aminopeptidase with homocysteine-thiolactonase activity; protects cells against homocysteine toxicity; has bleomycin hydrolase activity in vitro; transcription is regulated by galactose via Gal4p; orthologous to human BLMH
Synonyms YNL239W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG4128 --DHY--

KOGs classification KOGs description
METABOLISM Bleomycin hydrolases and aminopeptidases of cysteine protease family

Species KOG link NCBI link UniProt link
Drosophila melanogaster (Dme) 7290931 GI:7290931
Homo sapiens (Hsa) Hs4557367
(BLMH)		 GI:4557367 Q13867
Saccharomyces cerevisiae (Sce) YNL239w
(S000005183)		 GI:6324090
Drosophila melanogaster (Dme) 7302374 GI:20130175 A1ZBU9


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
TAS
HsaBLMH
GO:0005737 cytoplasm C
IDA
SceS000005183
GO:0005739 mitochondrion C
IDA
SceS000005183
GO:0003676 nucleic acid binding F
TAS
SceS000005183
GO:0004177 aminopeptidase activity F
TAS
HsaBLMH
GO:0004180 carboxypeptidase activity F
TAS
HsaBLMH
GO:0005515 protein binding F
IPI
HsaBLMH
GO:0008234 cysteine-type peptidase activity F
IDA
SceS000005183
TAS
HsaBLMH
GO:0030528 transcription regulator activity F
IDA
SceS000005183
GO:0006082 organic acid metabolic process P
RCA
SceS000005183
GO:0043418 homocysteine catabolic process P
IDA
SceS000005183
IMP
SceS000005183
GO:0046677 response to antibiotic P
IDA
SceS000005183
GO:0055114 oxidation reduction P
RCA
SceS000005183

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
330

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) BLMH GI:4557367 Q13867
Pan troglodytes (Ptr) BLMH GI:114668296
Canis familiaris (Cfa) BLMH GI:73967297
Mus musculus (Mmu) Blmh
(MGI:1345186)		 GI:30519997 Q8R016
Rattus norvegicus (Rno) Blmh
(RGD:1304668)		 GI:77681960
Gallus gallus (Gga) BLMH GI:45384138
Drosophila melanogaster (Dme) CG1440
(FBgn0030038)		 GI:161077632
Anopheles gambiae (Aga) AgaP_AGAP001341 GI:118794899
Saccharomyces cerevisiae (Sce) LAP3
(S000005183)		 GI:27808714
Eremothecium gossypii (Ego) AGOS_ABL204W GI:45185026
Magnaporthe grisea (Mgr) MGG_02695 GI:39970457
Neurospora crassa (Ncr) NCU08333.1 GI:32417802


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005625 soluble fraction C
IDA
MmuMGI:1345186
GO:0005634 nucleus C
TAS
HsaBLMH
GO:0005737 cytoplasm C
IDA
SceS000005183
GO:0005739 mitochondrion C
IDA
SceS000005183
GO:0003676 nucleic acid binding F
TAS
SceS000005183
GO:0004177 aminopeptidase activity F
TAS
HsaBLMH
GO:0004180 carboxypeptidase activity F
TAS
HsaBLMH
GO:0004197 cysteine-type endopeptidase activity F
ISS
DmeFBgn0030038
GO:0005515 protein binding F
IPI
HsaBLMH
GO:0008233 peptidase activity F
IMP
MmuMGI:1345186
GO:0008234 cysteine-type peptidase activity F
IDA
SceS000005183
TAS
HsaBLMH
GO:0030528 transcription regulator activity F
IDA
SceS000005183
GO:0006082 organic acid metabolic process P
RCA
SceS000005183
GO:0008152 metabolic process P
IMP
MmuMGI:1345186
GO:0009636 response to toxin P
IMP
MmuMGI:1345186
GO:0042493 response to drug P
IMP
MmuMGI:1345186
GO:0043418 homocysteine catabolic process P
IDA
SceS000005183
IMP
SceS000005183
GO:0046677 response to antibiotic P
IDA
SceS000005183
GO:0055114 oxidation reduction P
RCA
SceS000005183

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_6459

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga3417 ENSANGP00000016829
Anopheles gambiae (Aga) aga3418 ENSANGP00000022498
Ashbya gossypii (Ago) ago388 ABL204W
Candida glabrata (Cgl) cgl3321 CAGL0J07568g
Drosophila melanogaster (Dme) dme16990 CG1440-PA
(FBgn0030038)
Danio rerio (Dre) dre6535 ENSDARP00000035781
Takifugu rubripes (Fru) fru28712 SINFRUP00000146030
Gallus gallus (Gga) gga8921 ENSGALP00000006762
(BLMH)		 P87362
Homo sapiens (Hsa) hsa13385 ENSP00000261714
(BLMH)		 Q13867
Mus musculus (Mmu) mmu4277 ENSMUSP00000021197
(MGI:1345186)		 Q8R016
Neurospora crassa (Ncr) ncr8122 NCU08333.2
Rattus norvegicus (Rno) rno5674 ENSRNOP00000005125
(RGD:1304668)		 P70645
Saccharomyces cerevisiae (Sce) sce5360 YNL239W
(S000005183)
Yarrowia lipolytica (Yli) yli5592 YALI0F05940g
Yarrowia lipolytica (Yli) yli6096 YALI0F17974g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005625 soluble fraction C
IDA
MmuMGI:1345186
GO:0005737 cytoplasm C
IDA
SceS000005183
GO:0005739 mitochondrion C
IDA
SceS000005183
GO:0003676 nucleic acid binding F
TAS
SceS000005183
GO:0004197 cysteine-type endopeptidase activity F
ISS
DmeFBgn0030038
GO:0008233 peptidase activity F
IMP
MmuMGI:1345186
GO:0008234 cysteine-type peptidase activity F
IDA
SceS000005183
GO:0030528 transcription regulator activity F
IDA
SceS000005183
GO:0006082 organic acid metabolic process P
RCA
SceS000005183
GO:0008152 metabolic process P
IMP
MmuMGI:1345186
GO:0009636 response to toxin P
IMP
MmuMGI:1345186
GO:0042493 response to drug P
IMP
MmuMGI:1345186
GO:0043418 homocysteine catabolic process P
IDA
SceS000005183
IMP
SceS000005183
GO:0046677 response to antibiotic P
IDA
SceS000005183
GO:0055114 oxidation reduction P
RCA
SceS000005183

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GO info in one table:

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