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Search term: YNL241C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name ZWF1
SGD link S000005185
Alternative ID YNL241C
Description Glucose-6-phosphate dehydrogenase (G6PD), catalyzes the first step of the pentose phosphate pathway; involved in adapting to oxidatve stress; homolog of the human G6PD which is deficient in patients with hemolytic anemia
Synonyms YNL241C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0563 ACDHYPE

KOGs classification KOGs description
METABOLISM Glucose-6-phosphate 1-dehydrogenase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g09420 GI:3482917
Arabidopsis thaliana (Ath) At1g24280 GI:15221719
Arabidopsis thaliana (Ath) At3g27300 GI:15232132
Arabidopsis thaliana (Ath) At5g13110 GI:15240007
Arabidopsis thaliana (Ath) At5g35790 GI:15238612
Arabidopsis thaliana (Ath) At5g40760 GI:15237485
Caenorhabditis elegans (Cel) CE05163
(WBGene00007108)		 GI:17538218 Q27464
Drosophila melanogaster (Dme) 7293627 GI:539442
Drosophila melanogaster (Dme) 7296516 GI:7296516
Homo sapiens (Hsa) Hs21614520 GI:21614520
Homo sapiens (Hsa) Hs4758498_1 GI:4758498
Homo sapiens (Hsa) HsM4503845 GI:4503845
Saccharomyces cerevisiae (Sce) YNL241c
(S000005185)		 GI:6324088 P11412
Schizosaccharomyces pombe (Spo) SPAC3A12.18 GI:19114256 O00091
Schizosaccharomyces pombe (Spo) SPAC3C7.13c GI:19114526 O14137
Schizosaccharomyces pombe (Spo) SPCC794.01c GI:19075249 O59812
Encephalitozoon cuniculi (Ecu) ECU08g1850 GI:19173509 Q8SR89
Arabidopsis thaliana (Ath) At1g09420 GI:3482917
Arabidopsis thaliana (Ath) At1g24280 GI:15221719
Arabidopsis thaliana (Ath) At3g27300 GI:15232132
Arabidopsis thaliana (Ath) At5g13110 GI:15240007
Arabidopsis thaliana (Ath) At5g35790 GI:15238612
Arabidopsis thaliana (Ath) At5g40760 GI:15237485
Caenorhabditis elegans (Cel) CE05163
(WBGene00007108)		 GI:17538218 Q27464
Drosophila melanogaster (Dme) 7293627 GI:539442
Drosophila melanogaster (Dme) 7296516 GI:7296516
Homo sapiens (Hsa) Hs21614520 GI:21614520
Homo sapiens (Hsa) Hs4758498_1 GI:4758498
Homo sapiens (Hsa) HsM4503845 GI:4503845
Saccharomyces cerevisiae (Sce) YNL241c
(S000005185)		 GI:6324088 P11412
Schizosaccharomyces pombe (Spo) SPAC3A12.18 GI:19114256 O00091
Schizosaccharomyces pombe (Spo) SPAC3C7.13c GI:19114526 O14137
Schizosaccharomyces pombe (Spo) SPCC794.01c GI:19075249 O59812
Encephalitozoon cuniculi (Ecu) ECU08g1850 GI:19173509 Q8SR89


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000005185
ISS
SpoSPAC3A12.18
SPAC3C7.13c
SPCC794.01c
GO:0005829 cytosol C
IDA
SpoSPAC3A12.18
SPCC794.01c
ISS
AthAt5g40760
At3g27300
GO:0009507 chloroplast C
IDA
AthAt3g27300
At5g35790
ISS
AthAt5g13110
At5g35790
At1g24280
At1g09420
GO:0004345 glucose-6-phosphate dehydrogenase
activity		 F
IDA
AthAt3g27300
At5g35790
At5g40760
At1g24280
At5g13110
IMP
SceS000005185
ISS
AthAt3g27300
At5g40760
At1g24280
At1g09420
At5g35790
At5g13110
SceS000005185
SpoSPAC3A12.18
SPAC3C7.13c
SPCC794.01c
GO:0005515 protein binding F
IPI
AthAt5g35790
At1g24280
GO:0000003 reproduction P
IMP
CelWBGene00007108
GO:0006006 glucose metabolic process P
IDA
AthAt3g27300
At5g40760
At1g24280
At5g35790
At5g13110
ISS
AthAt1g09420
At3g27300
At5g40760
At5g35790
At5g13110
At1g24280
GO:0006740 NADPH regeneration P
IMP
SceS000005185
GO:0009051 pentose-phosphate shunt, oxidative
branch		 P
IC
SpoSPAC3C7.13c
SPCC794.01c
IDA
AthAt5g35790
At1g24280
At3g27300
At5g13110
At5g40760
IMP
SceS000005185
ISS
SceS000005185
SpoSPAC3A12.18
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00007108
GO:0033554 cellular response to stress P
IEP
SpoSPAC3A12.18
SPAC3C7.13c
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00007108
GO:0042542 response to hydrogen peroxide P
IMP
SceS000005185
GO:0046686 response to cadmium ion P
IEP
AthAt3g27300
GO:0051156 glucose 6-phosphate metabolic process P
IC
SpoSPAC3A12.18
SPAC3C7.13c
SPCC794.01c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
37906

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) G6PD GI:109389365
Canis familiaris (Cfa) G6PD GI:74009187
Mus musculus (Mmu) G6pdx
(MGI:105979)		 GI:6996917 Q00612
Rattus norvegicus (Rno) G6pd GI:8393381
Drosophila melanogaster (Dme) Zw
(FBgn0004057)		 GI:24643350
Anopheles gambiae (Aga) AgaP_AGAP010739 GI:158289817
Anopheles gambiae (Aga) AgaP_AGAP012678 GI:158284463
Caenorhabditis elegans (Cel) glucose-6-phosphate-1-dehydrogen GI:17538218 Q27464
Schizosaccharomyces pombe (Spo) zwf1
(SPAC3A12.18)		 GI:63054535 O00091
Saccharomyces cerevisiae (Sce) ZWF1
(S000005185)		 GI:6324088 P11412
Kluyveromyces lactis (Kla) G6PD_KLULA GI:50307901
Eremothecium gossypii (Ego) AGOS_ABL206C GI:45185024
Magnaporthe grisea (Mgr) MGG_09926 GI:145605357
Neurospora crassa (Ncr) NCU09111.1 GI:32422119
Arabidopsis thaliana (Ath) G6PD5 GI:145332697
Arabidopsis thaliana (Ath) G6PD6 GI:15237485
Oryza sativa (Osa) Os04g0485300 GI:115459064
Oryza sativa (Osa) Os02g0600400 GI:115447131
Plasmodium falciparum (Pfa) PF14_0511 GI:124809803


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
PfaPF14_0511
GO:0005625 soluble fraction C
ISO
MmuMGI:105979
GO:0005634 nucleus C
ISO
MmuMGI:105979
GO:0005737 cytoplasm C
IDA
HsaG6PD
SceS000005185
ISS
SpoSPAC3A12.18
GO:0005792 microsome C
ISO
MmuMGI:105979
GO:0005813 centrosome C
IDA
HsaG6PD
GO:0005829 cytosol C
IDA
HsaG6PD
SpoSPAC3A12.18
ISO
MmuMGI:105979
ISS
AthG6PD5
G6PD6
GO:0009507 chloroplast C
IDA
AthG6PD5
GO:0009898 internal side of plasma membrane C
IDA
HsaG6PD
GO:0043231 intracellular membrane-bounded
organelle		 C
IDA
HsaG6PD
GO:0004345 glucose-6-phosphate dehydrogenase
activity		 F
IDA
AthG6PD5
G6PD6
MmuMGI:105979
IMP
DmeFBgn0004057
HsaG6PD
MmuMGI:105979
SceS000005185
ISO
MmuMGI:105979
ISS
AthG6PD5
G6PD6
DmeFBgn0004057
SceS000005185
SpoSPAC3A12.18
TAS
DmeFBgn0004057
GO:0005529 sugar binding F
ISO
MmuMGI:105979
GO:0005536 glucose binding F
IDA
HsaG6PD
IMP
HsaG6PD
ISO
MmuMGI:105979
GO:0017057 6-phosphogluconolactonase activity F
ISS
PfaPF14_0511
GO:0042803 protein homodimerization activity F
IPI
HsaG6PD
MmuMGI:105979
GO:0050661 NADP or NADPH binding F
IDA
HsaG6PD
ISO
MmuMGI:105979
GO:0001816 cytokine production P
IMP
HsaG6PD
MmuMGI:105979
GO:0001998 angiotensin mediated vasoconstriction involved in
regulation of systemic arterial blood
pressure		 P
IMP
MmuMGI:105979
GO:0002033 vasodilation by angiotensin involved in regulation
of systemic arterial blood pressure		 P
IMP
MmuMGI:105979
GO:0006006 glucose metabolic process P
IDA
AthG6PD5
G6PD6
ISS
AthG6PD5
G6PD6
GO:0006098 pentose-phosphate shunt P
IDA
HsaG6PD
ISO
MmuMGI:105979
NAS
DmeFBgn0004057
TAS
PfaPF14_0511
GO:0006629 lipid metabolic process P
TAS
HsaG6PD
GO:0006695 cholesterol biosynthetic process P
IMP
HsaG6PD
GO:0006740 NADPH regeneration P
IMP
HsaG6PD
SceS000005185
GO:0006741 NADP biosynthetic process P
IDA
MmuMGI:105979
IMP
MmuMGI:105979
GO:0006749 glutathione metabolic process P
IMP
HsaG6PD
MmuMGI:105979
GO:0006979 response to oxidative stress P
IMP
MmuMGI:105979
GO:0009051 pentose-phosphate shunt, oxidative
branch		 P
IDA
AthG6PD5
G6PD6
IMP
HsaG6PD
SceS000005185
ISO
MmuMGI:105979
ISS
SceS000005185
SpoSPAC3A12.18
GO:0010734 negative regulation of protein amino acid
glutathionylation		 P
IMP
HsaG6PD
GO:0019322 pentose biosynthetic process P
IDA
HsaG6PD
MmuMGI:105979
IMP
MmuMGI:105979
GO:0032613 interleukin-10 production P
IMP
MmuMGI:105979
GO:0032615 interleukin-12 production P
IMP
MmuMGI:105979
GO:0033554 cellular response to stress P
IEP
SpoSPAC3A12.18
GO:0034599 cellular response to oxidative
stress		 P
IMP
HsaG6PD
GO:0040014 regulation of multicellular organism
growth		 P
IMP
MmuMGI:105979
GO:0042542 response to hydrogen peroxide P
IMP
SceS000005185
GO:0043249 erythrocyte maturation P
IMP
HsaG6PD
GO:0045471 response to ethanol P
ISO
MmuMGI:105979
GO:0045767 regulation of anti-apoptosis P
ISO
MmuMGI:105979
GO:0046390 ribose phosphate biosynthetic process P
IMP
HsaG6PD
GO:0046686 response to cadmium ion P
IEP
AthG6PD5
GO:0048821 erythrocyte development P
IMP
MmuMGI:105979
GO:0051156 glucose 6-phosphate metabolic process P
IC
SpoSPAC3A12.18
IMP
HsaG6PD
ISO
MmuMGI:105979
GO:0055114 oxidation reduction P
IMP
HsaG6PD

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_473

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga14011 ENSANGP00000012074
Anopheles gambiae (Aga) aga7709 ENSANGP00000018551
Anopheles gambiae (Aga) aga7710 ENSANGP00000028421
Ashbya gossypii (Ago) ago386 ABL206C
Arabidopsis thaliana (Ath) ath2620 At1g24280.1
Arabidopsis thaliana (Ath) ath15083 At3g27300.1
Arabidopsis thaliana (Ath) ath23498 At5g13110.1
Arabidopsis thaliana (Ath) ath25357 At5g35790.1
Arabidopsis thaliana (Ath) ath25852 At5g40760.1
Caenorhabditis elegans (Cel) cel105 B0035.5
(CE05163;
WBGene00007108)
Candida glabrata (Cgl) cgl3323 CAGL0J07612g
Cryptococcus neoformans (Cne) cne4414 177.m03167
Dictyostelium discoideum (Ddi) ddi1469 DDB0217233
Dictyostelium discoideum (Ddi) ddi11599 DDB0231285
Debaryomyces hansenii (Dha) dha1929 DEHA0C11286g
Drosophila melanogaster (Dme) dme18681 CG12529-PA
(FBgn0004057)
Drosophila melanogaster (Dme) dme18682 CG12529-PB
(FBgn0004057)
Danio rerio (Dre) dre30360 ENSDARP00000001421
(LOC570579)
Danio rerio (Dre) dre20801 ENSDARP00000015257
Escherichia coli (Eco) eco1808 16129805
Encephalitozoon cuniculi (Ecu) ecu340 19173509
Takifugu rubripes (Fru) fru9264 SINFRUP00000143893
Takifugu rubripes (Fru) fru17001 SINFRUP00000147275
Takifugu rubripes (Fru) fru18421 SINFRUP00000161861
Gallus gallus (Gga) gga12478 ENSGALP00000003916
Gallus gallus (Gga) gga12477 ENSGALP00000003917
(H6PD)
Homo sapiens (Hsa) hsa223 ENSP00000054661
Homo sapiens (Hsa) hsa33658 ENSP00000291567
(G6PD)		 P11413-1
Homo sapiens (Hsa) hsa33657 ENSP00000342362
Kluyveromyces lactis (Kla) kla2943 KLLA0D19855g
Mus musculus (Mmu) mmu29172 ENSMUSP00000004327
(MGI:105979)		 Q00612
Mus musculus (Mmu) mmu19465 ENSMUSP00000030830
(MGI:2140356)		 A2A7A7
Mus musculus (Mmu) mmu20120 ENSMUSP00000051649
Neurospora crassa (Ncr) ncr8879 NCU09111.2
Oryza sativa (Osa) osa26806 4142.m00160
Oryza sativa (Osa) osa37317 4978.m00183
Oryza sativa (Osa) osa68129 6901.m00162
Oryza sativa (Osa) osa85434 8377.m00132
Plasmodium falciparum (Pfa) pfa1193 PF14_0511
Rattus norvegicus (Rno) rno24455 ENSRNOP00000023543
(RGD:1306562)
Saccharomyces cerevisiae (Sce) sce5362 YNL241C
(S000005185)
Schizosaccharomyces pombe (Spo) spo1041 SPAC3A12.18 O00091
Schizosaccharomyces pombe (Spo) spo1723 SPAC3C7.13c O14137
Yarrowia lipolytica (Yli) yli4795 YALI0E22649g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
PfaPF14_0511
GO:0005625 soluble fraction C
ISO
MmuMGI:105979
GO:0005634 nucleus C
ISO
MmuMGI:105979
GO:0005737 cytoplasm C
IDA
SceS000005185
ISS
SpoSPAC3A12.18
SPAC3C7.13c
GO:0005792 microsome C
IDA
MmuMGI:2140356
ISO
MmuMGI:105979
MGI:2140356
GO:0005829 cytosol C
IDA
SpoSPAC3A12.18
ISO
MmuMGI:105979
ISS
AthAt5g40760
At3g27300
GO:0009507 chloroplast C
IDA
AthAt3g27300
At5g35790
ISS
AthAt5g13110
At5g35790
At1g24280
GO:0004345 glucose-6-phosphate dehydrogenase
activity		 F
IDA
AthAt3g27300
At5g35790
At5g40760
At1g24280
At5g13110
MmuMGI:105979
MGI:2140356
IMP
DmeFBgn0004057
MmuMGI:105979
SceS000005185
ISO
MmuMGI:105979
MGI:2140356
ISS
AthAt3g27300
At5g40760
At1g24280
At5g35790
At5g13110
DmeFBgn0004057
SceS000005185
SpoSPAC3A12.18
SPAC3C7.13c
TAS
DmeFBgn0004057
GO:0005515 protein binding F
IPI
AthAt5g35790
At1g24280
GO:0005529 sugar binding F
ISO
MmuMGI:105979
MGI:2140356
GO:0005536 glucose binding F
ISO
MmuMGI:105979
GO:0017057 6-phosphogluconolactonase activity F
IDA
MmuMGI:2140356
ISS
PfaPF14_0511
GO:0042803 protein homodimerization activity F
IPI
MmuMGI:105979
GO:0050661 NADP or NADPH binding F
ISO
MmuMGI:105979
MGI:2140356
GO:0000003 reproduction P
IMP
CelWBGene00007108
GO:0001816 cytokine production P
IMP
MmuMGI:105979
GO:0001998 angiotensin mediated vasoconstriction involved in
regulation of systemic arterial blood
pressure		 P
IMP
MmuMGI:105979
GO:0002033 vasodilation by angiotensin involved in regulation
of systemic arterial blood pressure		 P
IMP
MmuMGI:105979
GO:0005975 carbohydrate metabolic process P
ISO
MmuMGI:2140356
GO:0006006 glucose metabolic process P
IDA
AthAt3g27300
At5g40760
At1g24280
At5g35790
At5g13110
ISS
AthAt3g27300
At5g40760
At5g35790
At5g13110
At1g24280
GO:0006098 pentose-phosphate shunt P
IDA
MmuMGI:2140356
ISO
MmuMGI:105979
NAS
DmeFBgn0004057
TAS
PfaPF14_0511
GO:0006739 NADP metabolic process P
ISO
MmuMGI:2140356
GO:0006740 NADPH regeneration P
IMP
SceS000005185
GO:0006741 NADP biosynthetic process P
IDA
MmuMGI:105979
IMP
MmuMGI:105979
GO:0006749 glutathione metabolic process P
IMP
MmuMGI:105979
GO:0006979 response to oxidative stress P
IMP
MmuMGI:105979
GO:0009051 pentose-phosphate shunt, oxidative
branch		 P
IC
SpoSPAC3C7.13c
IDA
AthAt5g35790
At1g24280
At3g27300
At5g13110
At5g40760
IMP
SceS000005185
ISO
MmuMGI:105979
ISS
SceS000005185
SpoSPAC3A12.18
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00007108
GO:0019322 pentose biosynthetic process P
IDA
MmuMGI:105979
IMP
MmuMGI:105979
GO:0032613 interleukin-10 production P
IMP
MmuMGI:105979
GO:0032615 interleukin-12 production P
IMP
MmuMGI:105979
GO:0033554 cellular response to stress P
IEP
SpoSPAC3A12.18
SPAC3C7.13c
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00007108
GO:0040014 regulation of multicellular organism
growth		 P
IMP
MmuMGI:105979
GO:0042542 response to hydrogen peroxide P
IMP
SceS000005185
GO:0045471 response to ethanol P
ISO
MmuMGI:105979
GO:0045767 regulation of anti-apoptosis P
ISO
MmuMGI:105979
GO:0046686 response to cadmium ion P
IEP
AthAt3g27300
GO:0048821 erythrocyte development P
IMP
MmuMGI:105979
GO:0051156 glucose 6-phosphate metabolic process P
IC
SpoSPAC3A12.18
SPAC3C7.13c
ISO
MmuMGI:105979

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC3A12.18
(O00091)		 YNL241C
(S000005185)
SPCC794.01c
(O59812)		 YNL241C
(S000005185)
SPAC3C7.13c
(O14137)		 YNL241C
(S000005185)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000005185
ISS
SpoSPAC3A12.18
SPAC3C7.13c
SPCC794.01c
GO:0005829 cytosol C
IDA
SpoSPAC3A12.18
SPCC794.01c
GO:0004345 glucose-6-phosphate dehydrogenase
activity		 F
IMP
SceS000005185
ISS
SceS000005185
SpoSPAC3A12.18
SPAC3C7.13c
SPCC794.01c
GO:0006740 NADPH regeneration P
IMP
SceS000005185
GO:0009051 pentose-phosphate shunt, oxidative
branch		 P
IC
SpoSPAC3C7.13c
SPCC794.01c
IMP
SceS000005185
ISS
SceS000005185
SpoSPAC3A12.18
GO:0033554 cellular response to stress P
IEP
SpoSPAC3A12.18
SPAC3C7.13c
GO:0042542 response to hydrogen peroxide P
IMP
SceS000005185
GO:0051156 glucose 6-phosphate metabolic process P
IC
SpoSPAC3A12.18
SPAC3C7.13c
SPCC794.01c

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Query species:

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GO info in one table:

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