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Search term: YNL281W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name HCH1
SGD link S000005225
Alternative ID YNL281W
Description Heat shock protein regulator that binds to Hsp90p and may stimulate ATPase activity; originally identified as a high-copy number suppressor of a HSP90 loss-of-function mutation; GFP-fusion protein localizes to the cytoplasm and nucleus
Synonyms YNL281W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2936 ACDHYPE

KOGs classification KOGs description
POORLY CHARACTERIZED Uncharacterized conserved protein

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g12050 GI:18399461
Arabidopsis thaliana (Ath) At5g58110 GI:15242951
Caenorhabditis elegans (Cel) CE07817
(WBGene00007235)		 GI:17557460 Q93168
Drosophila melanogaster (Dme) 7302133 GI:20129691
Homo sapiens (Hsa) Hs6912280
(AHSA1)		 GI:6912280 O95433
Homo sapiens (Hsa) Hs17441336 GI:17441336
Homo sapiens (Hsa) Hs22045341 GI:22045341
Saccharomyces cerevisiae (Sce) YDR214w
(S000002622)		 GI:6320420 Q12449
Saccharomyces cerevisiae (Sce) YNL281w
(S000005225)		 GI:6324048 P53834
Schizosaccharomyces pombe (Spo) SPBC1711.08 GI:19112673 Q9P782
Encephalitozoon cuniculi (Ecu) ECU07g1300 GI:19074553 Q8SUX3


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000005225
GO:0005737 cytoplasm C
IDA
HsaAHSA1
SceS000005225
IPI
SceS000002622
ISS
HsaAHSA1
SpoSPBC1711.08
GO:0005829 cytosol C
IDA
SpoSPBC1711.08
GO:0001671 ATPase activator activity F
IDA
HsaAHSA1
SceS000002622
S000005225
ISS
HsaAHSA1
SpoSPBC1711.08
GO:0005515 protein binding F
IPI
HsaAHSA1
GO:0031072 heat shock protein binding F
ISS
SpoSPBC1711.08
GO:0051087 chaperone binding F
IDA
HsaAHSA1
SceS000005225
S000002622
GO:0006457 protein folding P
IGI
SceS000005225
IMP
SceS000002622
S000005225
IPI
SceS000005225
S000002622
ISS
HsaAHSA1
SpoSPBC1711.08
RCA
SceS000002622
GO:0006950 response to stress P
IMP
SceS000005225
S000002622
IPI
SceS000005225
S000002622
ISS
HsaAHSA1
GO:0008150 biological_process P
ND
AthAt5g58110
GO:0033554 cellular response to stress P
ISS
SpoSPBC1711.08

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
40048

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) HCH1
(S000005225)		 GI:6324048 P53834
Kluyveromyces lactis (Kla) KLLA0C12221g GI:50305565
Eremothecium gossypii (Ego) AGOS_AFR347C GI:45198865


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000005225
GO:0005737 cytoplasm C
IDA
SceS000005225
GO:0001671 ATPase activator activity F
IDA
SceS000005225
GO:0051087 chaperone binding F
IDA
SceS000005225
GO:0006457 protein folding P
IGI
SceS000005225
IMP
SceS000005225
IPI
SceS000005225
GO:0006950 response to stress P
IMP
SceS000005225
IPI
SceS000005225

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_8561

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago3539 AFR347C
Candida glabrata (Cgl) cgl2652 CAGL0I02992g
Debaryomyces hansenii (Dha) dha4971 DEHA0F13233g
Danio rerio (Dre) dre12463 ENSDARP00000032736
(ahsa1)		 Q5RIK4
Kluyveromyces lactis (Kla) kla1741 KLLA0C12221g
Plasmodium falciparum (Pfa) pfa2716 PFC0270w
Saccharomyces cerevisiae (Sce) sce5403 YNL281W
(S000005225)


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SceS000005225
GO:0005737 cytoplasm C
IDA
SceS000005225
GO:0001671 ATPase activator activity F
IDA
SceS000005225
GO:0051087 chaperone binding F
IDA
SceS000005225
GO:0006457 protein folding P
IGI
SceS000005225
IMP
SceS000005225
IPI
SceS000005225
GO:0006950 response to stress P
IMP
SceS000005225
IPI
SceS000005225

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