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Search term: YNL283C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name WSC2
SGD link S000005227
Alternative ID YNL283C
Description Partially redundant sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway involved in maintenance of cell wall integrity and recovery from heat shock; secretory pathway Wsc2p is required for the arrest of secretion response
Synonyms YNL283C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG4157 --DHYP-

KOGs classification KOGs description
METABOLISMCELLULAR PROCESSES AND SIGNALING beta-1,6-N-acetylglucosaminyltransferase, contains WSC domain

Species KOG link NCBI link UniProt link
Drosophila melanogaster (Dme) 7292215_2 GI:7292215
Drosophila melanogaster (Dme) 7293063 GI:18859981
Homo sapiens (Hsa) Hs13375642 GI:13375642 Q8NCW0
Homo sapiens (Hsa) Hs14755576 GI:14755576
Homo sapiens (Hsa) Hs21362020 GI:16551825 Q9UGU1
Homo sapiens (Hsa) Hs22064546 GI:22064546
Homo sapiens (Hsa) HsM14042982 GI:14042982
Saccharomyces cerevisiae (Sce) YHL028w
(S000001020)		 GI:6321759 P38739
Saccharomyces cerevisiae (Sce) YNL283c
(S000005227)		 GI:6324046 P53832
Saccharomyces cerevisiae (Sce) YOL105c_1 GI:6324467 Q12215
Saccharomyces cerevisiae (Sce) YOR008c
(S000005534)		 GI:6324581 P54867
Schizosaccharomyces pombe (Spo) SPBC3D6.14c GI:19112318


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005624 membrane fraction C
IDA
SceS000005534
ISS
SceS000005227
S000001020
GO:0005737 cytoplasm C
IDA
SceS000005227
GO:0005773 vacuole C
RCA
SceS000005534
GO:0005789 endoplasmic reticulum membrane C
IDA
SceS000001020
GO:0005886 plasma membrane C
IDA
SceS000005534
GO:0005933 cellular bud C
IDA
SceS000005227
GO:0005935 cellular bud neck C
IDA
SceS000005534
GO:0030427 site of polarized growth C
IDA
SceS000005227
GO:0030478 actin cap C
TAS
SceS000005534
GO:0043332 mating projection tip C
IDA
SceS000005534
S000005227
GO:0004888 transmembrane receptor activity F
IGI
SceS000005227
S000001020
S000005534
ISS
SceS000005227
S000001020
S000005534
GO:0000003 reproduction P
RCA
SceS000005534
GO:0001101 response to acid P
RCA
SceS000005534
GO:0006414 translational elongation P
RCA
SceS000001020
GO:0006616 SRP-dependent cotranslational protein targeting to
membrane, translocation		 P
ISS
SceS000001020
GO:0006950 response to stress P
IGI
SceS000001020
GO:0006970 response to osmotic stress P
IGI
SceS000005534
TAS
SceS000005534
GO:0006984 ER-nucleus signaling pathway P
RCA
SceS000005534
GO:0007047 cellular cell wall organization P
RCA
SceS000005534
GO:0007266 Rho protein signal transduction P
IGI
SceS000005227
S000005534
IMP
SceS000005534
ISS
SceS000005227
GO:0009408 response to heat P
IGI
SceS000005227
S000001020
IMP
SceS000005534
ISS
SceS000001020
S000005227
GO:0009966 regulation of signal transduction P
RCA
SceS000005534
GO:0030010 establishment of cell polarity P
IMP
SceS000005534
GO:0030036 actin cytoskeleton organization P
IMP
SceS000005534
TAS
SceS000005227
GO:0030242 peroxisome degradation P
IMP
SceS000005534
GO:0031505 fungal-type cell wall organization P
IGI
SceS000005227
IMP
SceS000005534
S000005227
GO:0045047 protein targeting to ER P
IMP
SceS000001020
GO:0045807 positive regulation of endocytosis P
IMP
SceS000005534
GO:0051049 regulation of transport P
RCA
SceS000005534
GO:0051098 regulation of binding P
RCA
SceS000005534
GO:0051301 cell division P
RCA
SceS000005534

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
117899

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) WSC2
(S000005227)		 GI:6324046 P53832
Saccharomyces cerevisiae (Sce) WSC3
(S000005465)		 GI:6324467 Q12215


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005624 membrane fraction C
ISS
SceS000005227
GO:0005737 cytoplasm C
IDA
SceS000005227
GO:0005933 cellular bud C
IDA
SceS000005227
GO:0030427 site of polarized growth C
IDA
SceS000005227
GO:0043332 mating projection tip C
IDA
SceS000005227
GO:0004888 transmembrane receptor activity F
IGI
SceS000005227
ISS
SceS000005227
GO:0007266 Rho protein signal transduction P
IGI
SceS000005227
ISS
SceS000005227
GO:0009408 response to heat P
IGI
SceS000005227
ISS
SceS000005227
GO:0030036 actin cytoskeleton organization P
TAS
SceS000005227
GO:0031505 fungal-type cell wall organization P
IGI
SceS000005227
IMP
SceS000005227

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_6374

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago3383 AFR191C
Ashbya gossypii (Ago) ago3541 AFR349W
Candida glabrata (Cgl) cgl782 CAGL0D02794g
Cryptococcus neoformans (Cne) cne969 163.m06440
Cryptococcus neoformans (Cne) cne4338 177.m03092
Debaryomyces hansenii (Dha) dha1677 DEHA0C05566g
Debaryomyces hansenii (Dha) dha2539 DEHA0D05423g
Debaryomyces hansenii (Dha) dha5032 DEHA0F14531g
Kluyveromyces lactis (Kla) kla1739 KLLA0C12177g
Kluyveromyces lactis (Kla) kla2980 KLLA0E00704g
Neurospora crassa (Ncr) ncr6793 NCU06981.2
Saccharomyces cerevisiae (Sce) sce2716 YHL028W
(S000001020)
Saccharomyces cerevisiae (Sce) sce5405 YNL283C
(S000005227)
Saccharomyces cerevisiae (Sce) sce5663 YOL105C
(S000005465)
Schizosaccharomyces pombe (Spo) spo2199 SPBC30B4.01c P87179
Yarrowia lipolytica (Yli) yli529 YALI0A16214g
Yarrowia lipolytica (Yli) yli5520 YALI0F04213g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005624 membrane fraction C
ISS
SceS000005227
S000001020
S000005465
GO:0005737 cytoplasm C
IDA
SceS000005227
GO:0005789 endoplasmic reticulum membrane C
IDA
SceS000001020
GO:0005886 plasma membrane C
NAS
SpoSPBC30B4.01c
GO:0005933 cellular bud C
IDA
SceS000005227
GO:0030427 site of polarized growth C
IDA
SceS000005227
GO:0043332 mating projection tip C
IDA
SceS000005465
S000005227
GO:0004888 transmembrane receptor activity F
IGI
SceS000005227
S000001020
S000005465
ISS
SceS000005227
S000005465
S000001020
SpoSPBC30B4.01c
GO:0030246 carbohydrate binding F
ISS
SpoSPBC30B4.01c
GO:0006414 translational elongation P
RCA
SceS000001020
GO:0006616 SRP-dependent cotranslational protein targeting to
membrane, translocation		 P
ISS
SceS000001020
GO:0006950 response to stress P
IGI
SceS000001020
GO:0007047 cellular cell wall organization P
ISS
SpoSPBC30B4.01c
GO:0007165 signal transduction P
ISS
SpoSPBC30B4.01c
GO:0007166 cell surface receptor linked signaling
pathway		 P
IC
SpoSPBC30B4.01c
GO:0007266 Rho protein signal transduction P
IGI
SceS000005227
S000005465
ISS
SceS000005465
S000005227
GO:0009408 response to heat P
IGI
SceS000005227
S000005465
S000001020
ISS
SceS000001020
S000005227
S000005465
GO:0023034 intracellular signaling pathway P
ISS
SpoSPBC30B4.01c
GO:0030036 actin cytoskeleton organization P
ISS
SpoSPBC30B4.01c
TAS
SceS000005465
S000005227
GO:0030242 peroxisome degradation P
IMP
SceS000005465
GO:0031505 fungal-type cell wall organization P
IGI
SceS000005227
IMP
SceS000005227
TAS
SceS000005465
GO:0033554 cellular response to stress P
ISS
SpoSPBC30B4.01c
GO:0045047 protein targeting to ER P
IMP
SceS000001020

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC30B4.01c
(P87179)		 YNL283C
(S000005227)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005624 membrane fraction C
ISS
SceS000005227
GO:0005737 cytoplasm C
IDA
SceS000005227
GO:0005886 plasma membrane C
NAS
SpoSPBC30B4.01c
GO:0005933 cellular bud C
IDA
SceS000005227
GO:0030427 site of polarized growth C
IDA
SceS000005227
GO:0043332 mating projection tip C
IDA
SceS000005227
GO:0004888 transmembrane receptor activity F
IGI
SceS000005227
ISS
SceS000005227
SpoSPBC30B4.01c
GO:0030246 carbohydrate binding F
ISS
SpoSPBC30B4.01c
GO:0007047 cellular cell wall organization P
ISS
SpoSPBC30B4.01c
GO:0007165 signal transduction P
ISS
SpoSPBC30B4.01c
GO:0007166 cell surface receptor linked signaling
pathway		 P
IC
SpoSPBC30B4.01c
GO:0007266 Rho protein signal transduction P
IGI
SceS000005227
ISS
SceS000005227
GO:0009408 response to heat P
IGI
SceS000005227
ISS
SceS000005227
GO:0023034 intracellular signaling pathway P
ISS
SpoSPBC30B4.01c
GO:0030036 actin cytoskeleton organization P
ISS
SpoSPBC30B4.01c
TAS
SceS000005227
GO:0031505 fungal-type cell wall organization P
IGI
SceS000005227
IMP
SceS000005227
GO:0033554 cellular response to stress P
ISS
SpoSPBC30B4.01c

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s.khadayate@ucl.ac.uk