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Search term: YNL292W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PUS4
SGD link S000005236
Alternative ID YNL292W
Description Pseudouridine synthase, catalyzes only the formation of pseudouridine-55 (Psi55), a highly conserved tRNA modification, in mitochondrial and cytoplasmic tRNAs; PUS4 overexpression leads to translational derepression of GCN4 (Gcd- phenotype)
Synonyms YNL292W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2529 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Pseudouridine synthase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g57150 GI:15230232
Arabidopsis thaliana (Ath) At5g14460 GI:15241405
Caenorhabditis elegans (Cel) CE16195
(WBGene00010478)		 GI:17553978 O17919
Drosophila melanogaster (Dme) 7291757 GI:17975520
Homo sapiens (Hsa) Hs4503337
(DKC1)		 GI:4503337 O60832
Homo sapiens (Hsa) Hs21040257 GI:18575011
Saccharomyces cerevisiae (Sce) YLR175w
(S000004165)		 GI:6323204 P33322
Saccharomyces cerevisiae (Sce) YNL292w
(S000005236)		 GI:6324037 P48567
Schizosaccharomyces pombe (Spo) SPAC29A4.04c GI:19115790 O14007
Schizosaccharomyces pombe (Spo) SPBC11C11.10 GI:19113192 O59721
Encephalitozoon cuniculi (Ecu) ECU05g1020 GI:19173642 Q8SRW0


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
HsaDKC1
SpoSPBC11C11.10
IMP
SceS000005236
ISS
SpoSPBC11C11.10
GO:0005654 nucleoplasm C
EXP
HsaDKC1
GO:0005697 telomerase holoenzyme complex C
IDA
HsaDKC1
GO:0005730 nucleolus C
IC
SceS000004165
IDA
AthAt3g57150
HsaDKC1
GO:0005732 small nucleolar ribonucleoprotein
complex		 C
ISS
SpoSPAC29A4.04c
GO:0005739 mitochondrion C
IMP
SceS000005236
ISS
SpoSPBC11C11.10
GO:0005829 cytosol C
IDA
AthAt3g57150
SpoSPAC29A4.04c
GO:0030686 90S preribosome C
IDA
SceS000004165
GO:0031429 box H/ACA snoRNP complex C
IPI
SceS000004165
GO:0003720 telomerase activity F
IDA
HsaDKC1
GO:0004730 pseudouridylate synthase activity F
IMP
SceS000004165
ISS
SceS000004165
SpoSPAC29A4.04c
GO:0005215 transporter activity F
ISS
AthAt5g14460
GO:0005515 protein binding F
IPI
HsaDKC1
GO:0009982 pseudouridine synthase activity F
IDA
SceS000005236
S000004165
IGI
SceS000005236
ISS
AthAt3g57150
SpoSPBC11C11.10
TAS
AthAt5g14460
At3g57150
GO:0000003 reproduction P
IMP
CelWBGene00010478
GO:0000154 rRNA modification P
ISS
SpoSPAC29A4.04c
GO:0000495 box H/ACA snoRNA 3'-end processing P
IMP
SceS000004165
GO:0002119 nematode larval development P
IMP
CelWBGene00010478
GO:0006364 rRNA processing P
IMP
SceS000004165
ISS
SpoSPAC29A4.04c
GO:0006399 tRNA metabolic process P
NAS
SpoSPAC29A4.04c
GO:0006400 tRNA modification P
IDA
SceS000005236
GO:0007004 telomere maintenance via telomerase P
TAS
HsaDKC1
GO:0008283 cell proliferation P
TAS
HsaDKC1
GO:0009451 RNA modification P
ISS
AthAt5g14460
GO:0031118 rRNA pseudouridine synthesis P
IMP
SceS000004165
GO:0031119 tRNA pseudouridine synthesis P
IC
SpoSPBC11C11.10
GO:0031120 snRNA pseudouridine synthesis P
IDA
SceS000004165
IMP
SceS000004165
GO:0040007 growth P
IMP
CelWBGene00010478
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00010478

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
31858

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) SPBC11C11.10 GI:19113192 O59721
Saccharomyces cerevisiae (Sce) PUS4
(S000005236)		 GI:6324037 P48567
Kluyveromyces lactis (Kla) KLLA0E13189g GI:50309075
Eremothecium gossypii (Ego) AGOS_AEL198W GI:45190409
Magnaporthe grisea (Mgr) MGG_08626 GI:39947759
Neurospora crassa (Ncr) NCU04153.1 GI:32405760


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPBC11C11.10
IMP
SceS000005236
ISS
SpoSPBC11C11.10
GO:0005739 mitochondrion C
IMP
SceS000005236
ISS
SpoSPBC11C11.10
GO:0009982 pseudouridine synthase activity F
IDA
SceS000005236
IGI
SceS000005236
ISS
SpoSPBC11C11.10
GO:0006400 tRNA modification P
IDA
SceS000005236
GO:0031119 tRNA pseudouridine synthesis P
IC
SpoSPBC11C11.10

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1666

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago2308 AEL198W
Arabidopsis thaliana (Ath) ath23653 At5g14460.1
Candida glabrata (Cgl) cgl4813 CAGL0M03619g
Cryptococcus neoformans (Cne) cne5275 179.m00124
Debaryomyces hansenii (Dha) dha3802 DEHA0E12716g
Danio rerio (Dre) dre3665 ENSDARP00000018787
Escherichia coli (Eco) eco3059 16131058
Gallus gallus (Gga) gga20897 ENSGALP00000014785
(TRUB1)
Homo sapiens (Hsa) hsa4641 ENSP00000298746
(TRUB1)		 Q8WWH5
Kluyveromyces lactis (Kla) kla3542 KLLA0E13189g
Mus musculus (Mmu) mmu13962 ENSMUSP00000026072
(MGI:1919383)		 Q8C0D0-2
Mus musculus (Mmu) mmu13961 ENSMUSP00000026073
(MGI:1919383)		 Q8C0D0-1
Neurospora crassa (Ncr) ncr4029 NCU04153.2
Oryza sativa (Osa) osa15572 2996.m00153
Oryza sativa (Osa) osa48915 5723.m00202
Plasmodium falciparum (Pfa) pfa396 PF10_0175
Rattus norvegicus (Rno) rno4315 ENSRNOP00000023309
(RGD:1308502)		 Q5M934
Rattus norvegicus (Rno) rno4316 ENSRNOP00000041469
Saccharomyces cerevisiae (Sce) sce5416 YNL292W
(S000005236)
Schizosaccharomyces pombe (Spo) spo2246 SPBC11C11.10 O59721
Yarrowia lipolytica (Yli) yli3766 YALI0D25234g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
MmuMGI:1919383
GO:0005634 nucleus C
IDA
SpoSPBC11C11.10
IMP
SceS000005236
ISS
SpoSPBC11C11.10
GO:0005739 mitochondrion C
IMP
SceS000005236
ISS
SpoSPBC11C11.10
GO:0020011 apicoplast C
ISS
PfaPF10_0175
GO:0003674 molecular_function F
ND
MmuMGI:1919383
GO:0005215 transporter activity F
ISS
AthAt5g14460
GO:0009982 pseudouridine synthase activity F
IDA
SceS000005236
IGI
SceS000005236
ISS
SpoSPBC11C11.10
TAS
AthAt5g14460
GO:0006400 tRNA modification P
IDA
SceS000005236
GO:0008150 biological_process P
ND
MmuMGI:1919383
GO:0009451 RNA modification P
ISS
AthAt5g14460
GO:0031119 tRNA pseudouridine synthesis P
IC
SpoSPBC11C11.10

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC11C11.10
(O59721)		 YNL292W
(S000005236)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPBC11C11.10
IMP
SceS000005236
ISS
SpoSPBC11C11.10
GO:0005739 mitochondrion C
IMP
SceS000005236
ISS
SpoSPBC11C11.10
GO:0009982 pseudouridine synthase activity F
IDA
SceS000005236
IGI
SceS000005236
ISS
SpoSPBC11C11.10
GO:0006400 tRNA modification P
IDA
SceS000005236
GO:0031119 tRNA pseudouridine synthesis P
IC
SpoSPBC11C11.10

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