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Search term: YNL293W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name MSB3
SGD link S000005237
Alternative ID YNL293W
Description GTPase-activating protein for Sec4p and several other Rab GTPases, regulates exocytosis via its action on Sec4p, also required for proper actin organization; similar to Msb4p; both Msb3p and Msb4p localize to sites of polarized growth
Synonyms YNL293W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2058 ACDHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Ypt/Rab GTPase activating protein

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g37290 GI:15228114
Arabidopsis thaliana (Ath) At2g39280 GI:15225062
Arabidopsis thaliana (Ath) At3g07890 GI:6648201
Arabidopsis thaliana (Ath) At3g55020 GI:11358030
Caenorhabditis elegans (Cel) CE08508 GI:17550744
Caenorhabditis elegans (Cel) CE29155
(WBGene00022880)		 GI:17538089 Q23419
Caenorhabditis elegans (Cel) CE29557 GI:17531475
Drosophila melanogaster (Dme) 7299317 GI:7299317
Drosophila melanogaster (Dme) 7300111 GI:7300111
Homo sapiens (Hsa) Hs13376023 GI:13376023
Homo sapiens (Hsa) Hs18580214 GI:18580214
Homo sapiens (Hsa) Hs22056446 GI:22056446
Homo sapiens (Hsa) Hs22058425 GI:22058425
Homo sapiens (Hsa) Hs8922167 GI:8922167
Saccharomyces cerevisiae (Sce) YMR055c
(S000004659)		 GI:6323700 P26448
Saccharomyces cerevisiae (Sce) YNL293w
(S000005237)		 GI:6324036 P48566
Saccharomyces cerevisiae (Sce) YOL112w
(S000005472)		 GI:6324460 Q12317
Schizosaccharomyces pombe (Spo) SPAC4G8.04 GI:19113976 Q09830
Schizosaccharomyces pombe (Spo) SPAC6F6.08c GI:19114813 P36618
Schizosaccharomyces pombe (Spo) SPCC4G3.09c GI:19075329 P87234


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000131 incipient cellular bud site C
IDA
SceS000005237
S000005472
GO:0000133 polarisome C
IPI
SceS000005237
S000005472
GO:0005575 cellular_component C
ND
SpoSPAC4G8.04
GO:0005634 nucleus C
IDA
SpoSPAC6F6.08c
GO:0005737 cytoplasm C
ISS
SpoSPCC4G3.09c
GO:0005770 late endosome C
IDA
CelWBGene00022880
GO:0005816 spindle pole body C
IDA
SceS000004659
SpoSPAC6F6.08c
GO:0005829 cytosol C
IDA
AthAt3g55020
SpoSPAC6F6.08c
SPCC4G3.09c
GO:0005934 cellular bud tip C
IDA
SceS000005237
S000005472
GO:0009507 chloroplast C
IDA
AthAt2g37290
GO:0005083 small GTPase regulator activity F
RCA
SceS000004659
GO:0005096 GTPase activator activity F
IGI
SpoSPAC6F6.08c
ISS
SpoSPAC4G8.04
TAS
SceS000004659
GO:0005097 Rab GTPase activator activity F
IDA
CelWBGene00022880
SceS000005237
S000005472
ISS
SceS000005237
SpoSPCC4G3.09c
GO:0005099 Ras GTPase activator activity F
RCA
SceS000004659
GO:0005515 protein binding F
IPI
SpoSPAC6F6.08c
GO:0000003 reproduction P
IMP
CelWBGene00022880
RCA
SceS000005472
GO:0000278 mitotic cell cycle P
RCA
SceS000004659
GO:0000279 M phase P
RCA
SceS000004659
GO:0000280 nuclear division P
RCA
SceS000004659
GO:0000917 barrier septum formation P
IMP
SpoSPAC6F6.08c
GO:0006887 exocytosis P
ISS
SpoSPCC4G3.09c
TAS
SceS000005237
GO:0007015 actin filament organization P
IGI
SceS000005472
S000005237
IPI
SceS000005237
S000005472
GO:0007059 chromosome segregation P
RCA
SceS000004659
GO:0007094 mitotic cell cycle spindle assembly
checkpoint		 P
IMP
SpoSPAC6F6.08c
GO:0007096 regulation of exit from mitosis P
TAS
SceS000004659
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00022880
GO:0009966 regulation of signal transduction P
RCA
SceS000005472
GO:0010687 site selection involved in cell cycle
cytokinesis		 P
ISS
SpoSPCC4G3.09c
GO:0016192 vesicle-mediated transport P
NAS
SpoSPAC4G8.04
GO:0019953 sexual reproduction P
RCA
SceS000005472
GO:0030447 filamentous growth P
RCA
SceS000005472
GO:0031030 negative regulation of septation initiation
signaling		 P
IGI
SpoSPAC6F6.08c
GO:0031578 mitotic cell cycle spindle orientation
checkpoint		 P
IGI
SceS000004659
IMP
SceS000004659
GO:0032313 regulation of Rab GTPase activity P
ISS
SpoSPCC4G3.09c
GO:0032851 positive regulation of Rab GTPase
activity		 P
IDA
CelWBGene00022880
GO:0048285 organelle fission P
RCA
SceS000004659
GO:0051129 negative regulation of cellular component
organization		 P
RCA
SceS000004659
GO:0051301 cell division P
RCA
SceS000004659
S000005472
GO:0051726 regulation of cell cycle P
RCA
SceS000004659

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
122171

Species Gene ID NCBI link UniProt link
Saccharomyces cerevisiae (Sce) MSB3
(S000005237)		 GI:6324036 P48566
Kluyveromyces lactis (Kla) KLLA0A07491g GI:50302793
Eremothecium gossypii (Ego) AGOS_AEL201W GI:45190406


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000131 incipient cellular bud site C
IDA
SceS000005237
GO:0000133 polarisome C
IPI
SceS000005237
GO:0005934 cellular bud tip C
IDA
SceS000005237
GO:0005097 Rab GTPase activator activity F
IDA
SceS000005237
ISS
SceS000005237
GO:0006887 exocytosis P
TAS
SceS000005237
GO:0007015 actin filament organization P
IGI
SceS000005237
IPI
SceS000005237

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_3766

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga6290 ENSANGP00000018856
Ashbya gossypii (Ago) ago2305 AEL201W
Caenorhabditis elegans (Cel) cel974 C04A2.1
(CE36523;
WBGene00015410)
Candida glabrata (Cgl) cgl4814 CAGL0M03641g
Debaryomyces hansenii (Dha) dha3773 DEHA0E12012g
Drosophila melanogaster (Dme) dme12884 CG5916-PA
(FBgn0038401)
Danio rerio (Dre) dre23762 ENSDARP00000045753
(LOC573452)
Danio rerio (Dre) dre23765 ENSDARP00000045883
(grtp1)		 Q6PBU5
Takifugu rubripes (Fru) fru3378 SINFRUP00000138432
Takifugu rubripes (Fru) fru27881 SINFRUP00000162940
Gallus gallus (Gga) gga2679 ENSGALP00000027118
(GRTP1)
Homo sapiens (Hsa) hsa9067 ENSP00000321850
(GRTP1)		 B4DV24
Kluyveromyces lactis (Kla) kla330 KLLA0A07491g
Mus musculus (Mmu) mmu25644 ENSMUSP00000079407
(MGI:1914040)		 Q9D3N8-1
Mus musculus (Mmu) mmu25645 ENSMUSP00000080588
(MGI:1914040)		 Q9D3N8-2
Neurospora crassa (Ncr) ncr4383 NCU04514.2
Plasmodium falciparum (Pfa) pfa1091 PF11_0151
Rattus norvegicus (Rno) rno12770 ENSRNOP00000026546
(RGD:1309210)
Saccharomyces cerevisiae (Sce) sce5417 YNL293W
(S000005237)
Saccharomyces cerevisiae (Sce) sce5670 YOL112W
(S000005472)
Schizosaccharomyces pombe (Spo) spo1331 SPCC4G3.09c P87234
Yarrowia lipolytica (Yli) yli1692 YALI0B22792g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000131 incipient cellular bud site C
IDA
SceS000005237
S000005472
GO:0000133 polarisome C
IPI
SceS000005237
S000005472
GO:0005737 cytoplasm C
ISS
SpoSPCC4G3.09c
GO:0005829 cytosol C
IDA
SpoSPCC4G3.09c
GO:0005934 cellular bud tip C
IDA
SceS000005237
S000005472
GO:0005097 Rab GTPase activator activity F
IDA
SceS000005237
S000005472
ISS
SceS000005237
SpoSPCC4G3.09c
GO:0000003 reproduction P
RCA
SceS000005472
GO:0006887 exocytosis P
ISS
SpoSPCC4G3.09c
TAS
SceS000005237
GO:0007015 actin filament organization P
IGI
SceS000005472
S000005237
IPI
SceS000005237
S000005472
GO:0009966 regulation of signal transduction P
RCA
SceS000005472
GO:0010687 site selection involved in cell cycle
cytokinesis		 P
ISS
SpoSPCC4G3.09c
GO:0019953 sexual reproduction P
RCA
SceS000005472
GO:0030447 filamentous growth P
RCA
SceS000005472
GO:0032313 regulation of Rab GTPase activity P
ISS
SpoSPCC4G3.09c
GO:0051301 cell division P
RCA
SceS000005472

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC4G3.09c
(P87234)		 YNL293W
(S000005237)