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Search term: YNL317W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PFS2
SGD link S000005261
Alternative ID YNL317W
Description Integral subunit of the pre-mRNA cleavage and polyadenylation factor (CPF) complex; plays an essential role in mRNA 3'-end formation by bridging different processing factors and thereby promoting the assembly of the processing complex
Synonyms YNL317W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0284 ACDHYPE

KOGs classification KOGs description
INFORMATION STORAGE AND PROCESSING Polyadenylation factor I complex, subunit PFS2

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At5g13480 GI:15240638
Caenorhabditis elegans (Cel) CE21113
(WBGene00011051)		 GI:17535491 Q9NAN8
Drosophila melanogaster (Dme) 7296695 GI:7296695
Homo sapiens (Hsa) Hs13129110
(WDR77)		 GI:13129110 Q9BQA1
Homo sapiens (Hsa) Hs19923529 GI:19923529
Saccharomyces cerevisiae (Sce) YNL317w
(S000005261)		 GI:6324012 P42841
Schizosaccharomyces pombe (Spo) SPAC12G12.14c GI:19113796 Q9UTN4
Encephalitozoon cuniculi (Ecu) ECU02g1400 GI:19074059 Q8SW96
Arabidopsis thaliana (Ath) At5g13480 GI:15240638
Caenorhabditis elegans (Cel) CE21113
(WBGene00011051)		 GI:17535491 Q9NAN8
Drosophila melanogaster (Dme) 7296695 GI:7296695
Homo sapiens (Hsa) Hs13129110
(WDR77)		 GI:13129110 Q9BQA1
Homo sapiens (Hsa) Hs19923529 GI:19923529
Saccharomyces cerevisiae (Sce) YNL317w
(S000005261)		 GI:6324012 P42841
Schizosaccharomyces pombe (Spo) SPAC12G12.14c GI:19113796 Q9UTN4
Encephalitozoon cuniculi (Ecu) ECU02g1400 GI:19074059 Q8SW96
Arabidopsis thaliana (Ath) At5g13480 GI:15240638
Caenorhabditis elegans (Cel) CE21113
(WBGene00011051)		 GI:17535491 Q9NAN8
Drosophila melanogaster (Dme) 7296695 GI:7296695
Homo sapiens (Hsa) Hs13129110
(WDR77)		 GI:13129110 Q9BQA1
Homo sapiens (Hsa) Hs19923529 GI:19923529
Saccharomyces cerevisiae (Sce) YNL317w
(S000005261)		 GI:6324012 P42841
Schizosaccharomyces pombe (Spo) SPAC12G12.14c GI:19113796 Q9UTN4
Encephalitozoon cuniculi (Ecu) ECU02g1400 GI:19074059 Q8SW96


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC12G12.14c
IGI
HsaWDR77
GO:0005737 cytoplasm C
IGI
HsaWDR77
GO:0005829 cytosol C
IDA
SpoSPAC12G12.14c
GO:0005847 mRNA cleavage and polyadenylation specificity
factor complex		 C
IDA
SpoSPAC12G12.14c
IPI
SceS000005261
TAS
SceS000005261
GO:0044428 nuclear part C
IDA
CelWBGene00011051
GO:0080008 CUL4 RING ubiquitin ligase complex C
IPI
AthAt5g13480
GO:0003674 molecular_function F
ND
SpoSPAC12G12.14c
GO:0003723 RNA binding F
IC
SceS000005261
GO:0005515 protein binding F
IPI
AthAt5g13480
HsaWDR77
GO:0030374 ligand-dependent nuclear receptor transcription
coactivator activity		 F
IGI
HsaWDR77
GO:0000003 reproduction P
IMP
CelWBGene00011051
GO:0000070 mitotic sister chromatid segregation P
IMP
SpoSPAC12G12.14c
GO:0000387 spliceosomal snRNP assembly P
EXP
HsaWDR77
GO:0002119 nematode larval development P
IMP
CelWBGene00011051
GO:0006353 transcription termination P
RCA
SceS000005261
GO:0006378 mRNA polyadenylation P
IDA
SceS000005261
IMP
SceS000005261
ISS
SpoSPAC12G12.14c
TAS
SceS000005261
GO:0006379 mRNA cleavage P
IDA
SceS000005261
IMP
SceS000005261
ISS
SpoSPAC12G12.14c
TAS
SceS000005261
GO:0006397 mRNA processing P
IGI
AthAt5g13480
GO:0009793 embryo development ending in seed
dormancy		 P
IMP
AthAt5g13480
GO:0009909 regulation of flower development P
IMP
AthAt5g13480
GO:0018996 molting cycle, collagen and cuticulin-based
cuticle		 P
IMP
CelWBGene00011051
GO:0031123 RNA 3'-end processing P
RCA
SceS000005261
GO:0031124 mRNA 3'-end processing P
IMP
SpoSPAC12G12.14c
GO:0040007 growth P
IMP
CelWBGene00011051
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00011051
GO:0040011 locomotion P
IMP
CelWBGene00011051
GO:2000045 regulation of G1/S transition of mitotic cell
cycle		 P
IMP
SpoSPAC12G12.14c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
56807

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) WDR33 GI:56243590
Pan troglodytes (Ptr) WDR33 GI:114580746
Canis familiaris (Cfa) WDR33 GI:73983997
Mus musculus (Mmu) Wdr33
(MGI:1921570)		 GI:21362285 Q3TSL0
Rattus norvegicus (Rno) Wdr33 GI:34878620
Gallus gallus (Gga) WDR33 GI:118094828
Caenorhabditis elegans (Cel) R06A4.9
(CE21113;
WBGene00011051)		 GI:17535491 Q9NAN8
Schizosaccharomyces pombe (Spo) pfs2
(SPAC12G12.14c)		 GI:19113796 Q9UTN4
Saccharomyces cerevisiae (Sce) PFS2
(S000005261)		 GI:6324012 P42841
Kluyveromyces lactis (Kla) KLLA0E07073g GI:50308531
Eremothecium gossypii (Ego) AGOS_ADL184W GI:45187689
Magnaporthe grisea (Mgr) MGG_05325 GI:145601923
Neurospora crassa (Ncr) NCU00037.1 GI:32403020
Arabidopsis thaliana (Ath) FY GI:79512802
Oryza sativa (Osa) Os01g0951000 GI:115442261


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000159 protein phosphatase type 2A complex C
TAS
AthFY
GO:0005575 cellular_component C
ND
AthFY
GO:0005634 nucleus C
IDA
AthFY
HsaWDR33
MmuMGI:1921570
SpoSPAC12G12.14c
TAS
AthFY
GO:0005737 cytoplasm C
IDA
AthFY
GO:0005829 cytosol C
IDA
SpoSPAC12G12.14c
GO:0005847 mRNA cleavage and polyadenylation specificity
factor complex		 C
IDA
SpoSPAC12G12.14c
IPI
SceS000005261
TAS
SceS000005261
GO:0016602 CCAAT-binding factor complex C
ISS
AthFY
GO:0044428 nuclear part C
IDA
CelWBGene00011051
GO:0080008 CUL4 RING ubiquitin ligase complex C
IPI
AthFY
GO:0003674 molecular_function F
ND
MmuMGI:1921570
SpoSPAC12G12.14c
GO:0003700 transcription factor activity F
IDA
AthFY
ISS
AthFY
TAS
AthFY
GO:0003723 RNA binding F
IC
SceS000005261
GO:0004674 protein serine/threonine kinase
activity		 F
ISS
AthFY
GO:0004722 protein serine/threonine phosphatase
activity		 F
ISS
AthFY
GO:0005515 protein binding F
IPI
AthFY
HsaWDR33
GO:0016566 specific transcriptional repressor
activity		 F
IDA
AthFY
GO:0031490 chromatin DNA binding F
IDA
AthFY
GO:0043565 sequence-specific DNA binding F
IDA
AthFY
GO:0000003 reproduction P
IMP
CelWBGene00011051
GO:0000070 mitotic sister chromatid segregation P
IMP
SpoSPAC12G12.14c
GO:0002119 nematode larval development P
IMP
CelWBGene00011051
GO:0006301 postreplication repair P
NAS
HsaWDR33
GO:0006353 transcription termination P
RCA
SceS000005261
GO:0006355 regulation of transcription, DNA-dependent P
ISS
AthFY
GO:0006378 mRNA polyadenylation P
IDA
SceS000005261
IMP
SceS000005261
ISS
SpoSPAC12G12.14c
TAS
SceS000005261
GO:0006379 mRNA cleavage P
IDA
SceS000005261
IMP
SceS000005261
ISS
SpoSPAC12G12.14c
TAS
SceS000005261
GO:0006397 mRNA processing P
IGI
AthFY
GO:0007283 spermatogenesis P
NAS
HsaWDR33
GO:0008150 biological_process P
ND
AthFY
MmuMGI:1921570
GO:0009414 response to water deprivation P
IMP
AthFY
GO:0009611 response to wounding P
IMP
AthFY
GO:0009740 gibberellic acid mediated signaling
pathway		 P
TAS
AthFY
GO:0009753 response to jasmonic acid stimulus P
IMP
AthFY
GO:0009793 embryo development ending in seed
dormancy		 P
IMP
AthFY
NAS
AthFY
GO:0009908 flower development P
IMP
AthFY
GO:0009909 regulation of flower development P
IMP
AthFY
GO:0009910 negative regulation of flower development P
IMP
AthFY
GO:0010077 maintenance of inflorescence meristem
identity		 P
IGI
AthFY
GO:0010582 floral meristem determinacy P
IGI
AthFY
GO:0018996 molting cycle, collagen and cuticulin-based
cuticle		 P
IMP
CelWBGene00011051
GO:0031123 RNA 3'-end processing P
RCA
SceS000005261
GO:0031124 mRNA 3'-end processing P
IMP
SpoSPAC12G12.14c
GO:0032582 negative regulation of gene-specific
transcription		 P
IDA
AthFY
GO:0040007 growth P
IMP
CelWBGene00011051
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00011051
GO:0040011 locomotion P
IMP
CelWBGene00011051
GO:2000045 regulation of G1/S transition of mitotic cell
cycle		 P
IMP
SpoSPAC12G12.14c

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2142

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga3440 ENSANGP00000016766
Ashbya gossypii (Ago) ago1557 ADL184W
Arabidopsis thaliana (Ath) ath23538 At5g13480.1
Caenorhabditis elegans (Cel) cel13417 R06A4.9
(CE21113;
WBGene00011051)
Candida glabrata (Cgl) cgl4834 CAGL0M04081g
Cryptococcus neoformans (Cne) cne5282 179.m00131
Debaryomyces hansenii (Dha) dha1369 DEHA0B15719g
Drosophila melanogaster (Dme) dme11089 CG1109-PA
(FBgn0046222)
Drosophila melanogaster (Dme) dme11090 CG1109-PB
(FBgn0046222)
Danio rerio (Dre) dre27280 ENSDARP00000027484
(wdr33)		 Q6DRI9
Danio rerio (Dre) dre27279 ENSDARP00000041259
Encephalitozoon cuniculi (Ecu) ecu138 19074059
Takifugu rubripes (Fru) fru22333 SINFRUP00000161556
Gallus gallus (Gga) gga23087 ENSGALP00000003172
(WDR33)
Homo sapiens (Hsa) hsa18569 ENSP00000325377
(WDR33)		 Q9C0J8
Kluyveromyces lactis (Kla) kla3267 KLLA0E07073g
Mus musculus (Mmu) mmu12449 ENSMUSP00000025264
(MGI:1921570)		 Q8C4Z4
Neurospora crassa (Ncr) ncr36 NCU00037.2
Oryza sativa (Osa) osa28795 4208.m00162
Plasmodium falciparum (Pfa) pfa5176 PFL1975c
Rattus norvegicus (Rno) rno13893 ENSRNOP00000017075
(RGD:1309230)
Saccharomyces cerevisiae (Sce) sce5441 YNL317W
(S000005261)
Schizosaccharomyces pombe (Spo) spo272 SPAC12G12.14c Q9UTN4
Yarrowia lipolytica (Yli) yli573 YALI0A17424g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
PfaPFL1975c
GO:0005634 nucleus C
IDA
MmuMGI:1921570
SpoSPAC12G12.14c
GO:0005829 cytosol C
IDA
SpoSPAC12G12.14c
GO:0005847 mRNA cleavage and polyadenylation specificity
factor complex		 C
IDA
SpoSPAC12G12.14c
IPI
SceS000005261
TAS
SceS000005261
GO:0044428 nuclear part C
IDA
CelWBGene00011051
GO:0080008 CUL4 RING ubiquitin ligase complex C
IPI
AthAt5g13480
GO:0003674 molecular_function F
ND
MmuMGI:1921570
PfaPFL1975c
SpoSPAC12G12.14c
GO:0003723 RNA binding F
IC
SceS000005261
GO:0005515 protein binding F
IPI
AthAt5g13480
GO:0000003 reproduction P
IMP
CelWBGene00011051
GO:0000070 mitotic sister chromatid segregation P
IMP
SpoSPAC12G12.14c
GO:0002119 nematode larval development P
IMP
CelWBGene00011051
GO:0006353 transcription termination P
RCA
SceS000005261
GO:0006378 mRNA polyadenylation P
IDA
SceS000005261
IMP
SceS000005261
ISS
SpoSPAC12G12.14c
TAS
SceS000005261
GO:0006379 mRNA cleavage P
IDA
SceS000005261
IMP
SceS000005261
ISS
SpoSPAC12G12.14c
TAS
SceS000005261
GO:0006397 mRNA processing P
IGI
AthAt5g13480
GO:0008150 biological_process P
ND
MmuMGI:1921570
PfaPFL1975c
GO:0009793 embryo development ending in seed
dormancy		 P
IMP
AthAt5g13480
GO:0009909 regulation of flower development P
IMP
AthAt5g13480
GO:0018996 molting cycle, collagen and cuticulin-based
cuticle		 P
IMP
CelWBGene00011051
GO:0031123 RNA 3'-end processing P
RCA
SceS000005261
GO:0031124 mRNA 3'-end processing P
IMP
SpoSPAC12G12.14c
GO:0040007 growth P
IMP
CelWBGene00011051
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00011051
GO:0040011 locomotion P
IMP
CelWBGene00011051
GO:2000045 regulation of G1/S transition of mitotic cell
cycle		 P
IMP
SpoSPAC12G12.14c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC12G12.14c
(Q9UTN4)		 YNL317W
(S000005261)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005634 nucleus C
IDA
SpoSPAC12G12.14c
GO:0005829 cytosol C
IDA
SpoSPAC12G12.14c
GO:0005847 mRNA cleavage and polyadenylation specificity
factor complex		 C
IDA
SpoSPAC12G12.14c
IPI
SceS000005261
TAS
SceS000005261
GO:0003674 molecular_function F
ND
SpoSPAC12G12.14c
GO:0003723 RNA binding F
IC
SceS000005261
GO:0000070 mitotic sister chromatid segregation P
IMP
SpoSPAC12G12.14c
GO:0006353 transcription termination P
RCA
SceS000005261
GO:0006378 mRNA polyadenylation P
IDA
SceS000005261
IMP
SceS000005261
ISS
SpoSPAC12G12.14c
TAS
SceS000005261
GO:0006379 mRNA cleavage P
IDA
SceS000005261
IMP
SceS000005261
ISS
SpoSPAC12G12.14c
TAS
SceS000005261
GO:0031123 RNA 3'-end processing P
RCA
SceS000005261
GO:0031124 mRNA 3'-end processing P
IMP
SpoSPAC12G12.14c
GO:2000045 regulation of G1/S transition of mitotic cell
cycle		 P
IMP
SpoSPAC12G12.14c

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