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Search term: YNL321W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name VNX1
SGD link S000005265
Alternative ID YNL321W
Description Low affinity vacuolar membrane localized monovalent cation/H+ antiporter; member of the calcium exchanger (CAX) family; potential Cdc28p substrate
Synonyms YNL321W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG1397 A---YP-

KOGs classification KOGs description
METABOLISM Ca2+/H+ antiporter VCX1 and related proteins

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g55720 GI:15222762
Arabidopsis thaliana (Ath) At1g55730 GI:15222766
Arabidopsis thaliana (Ath) At2g38170 GI:15224460
Arabidopsis thaliana (Ath) At3g13320 GI:9294538
Arabidopsis thaliana (Ath) At3g51860 GI:15231061
Arabidopsis thaliana (Ath) At5g01490 GI:11279543
Saccharomyces cerevisiae (Sce) YDL128w
(S000002286)		 GI:6320075 Q99385
Saccharomyces cerevisiae (Sce) YNL321w
(S000005265)		 GI:6324008 P42839
Schizosaccharomyces pombe (Spo) SPAC521.04c GI:19114011 Q9P7B3
Schizosaccharomyces pombe (Spo) SPCC1795.02c GI:19075542 O59768


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000324 fungal-type vacuole C
IDA
SceS000005265
S000002286
ISS
SpoSPCC1795.02c
GO:0005773 vacuole C
IDA
AthAt2g38170
At3g51860
At3g13320
GO:0005774 vacuolar membrane C
IDA
AthAt3g51860
At5g01490
TAS
AthAt2g38170
GO:0005783 endoplasmic reticulum C
IDA
SpoSPAC521.04c
SPCC1795.02c
GO:0005789 endoplasmic reticulum membrane C
IDA
SceS000005265
GO:0009705 plant-type vacuole membrane C
IDA
AthAt3g51860
At2g38170
At3g13320
At5g01490
GO:0012505 endomembrane system C
TAS
AthAt3g13320
GO:0016020 membrane C
IDA
AthAt2g38170
GO:0016021 integral to membrane C
ISS
SpoSPAC521.04c
GO:0008324 cation transmembrane transporter
activity		 F
ISS
SpoSPAC521.04c
GO:0015085 calcium ion transmembrane transporter
activity		 F
IDA
SceS000002286
IGI
AthAt2g38170
IMP
SceS000002286
ISS
SpoSPCC1795.02c
GO:0015368 calcium:cation antiporter activity F
IDA
AthAt5g01490
ISS
AthAt1g55730
At1g55720
At2g38170
At3g51860
At3g13320
At5g01490
GO:0015369 calcium:hydrogen antiporter activity F
IDA
AthAt3g13320
At3g51860
At2g38170
IGI
AthAt2g38170
At3g13320
IMP
AthAt5g01490
SceS000005265
ISS
AthAt3g51860
At5g01490
GO:0015385 sodium:hydrogen antiporter activity F
IMP
SceS000005265
GO:0015386 potassium:hydrogen antiporter activity F
IMP
SceS000005265
GO:0015491 cation:cation antiporter activity F
ISS
AthAt3g51860
At5g01490
At1g55730
At1g55720
NAS
AthAt3g51860
At1g55730
At5g01490
At1g55720
TAS
AthAt5g01490
GO:0006793 phosphorus metabolic process P
IGI
AthAt3g51860
GO:0006812 cation transport P
ISS
AthAt3g51860
At1g55730
At1g55720
SpoSPAC521.04c
GO:0006813 potassium ion transport P
IMP
SceS000005265
GO:0006814 sodium ion transport P
IGI
AthAt3g51860
IMP
SceS000005265
GO:0006816 calcium ion transport P
IDA
AthAt3g13320
At2g38170
SceS000002286
IGI
AthAt2g38170
At3g13320
At5g01490
IMP
SceS000002286
ISS
SpoSPCC1795.02c
GO:0006818 hydrogen transport P
IMP
SceS000005265
GO:0006828 manganese ion transport P
IGI
AthAt3g13320
GO:0006874 cellular calcium ion homeostasis P
IGI
AthAt3g51860
IMP
SceS000002286
SpoSPCC1795.02c
GO:0006882 cellular zinc ion homeostasis P
IGI
AthAt3g51860
IMP
AthAt2g38170
GO:0009624 response to nematode P
IEP
AthAt3g51860
GO:0009631 cold acclimation P
IMP
AthAt2g38170
GO:0009651 response to salt stress P
IMP
AthAt2g38170
GO:0009733 response to auxin stimulus P
IMP
AthAt5g01490
GO:0010351 lithium ion transport P
IGI
AthAt3g51860
GO:0015691 cadmium ion transport P
IGI
AthAt3g13320
GO:0030001 metal ion transport P
IMP
AthAt3g13320
TAS
AthAt3g13320
GO:0030026 cellular manganese ion homeostasis P
IGI
AthAt3g51860
IMP
AthAt2g38170
GO:0034220 ion transmembrane transport P
ISS
SpoSPAC521.04c
GO:0048364 root development P
IMP
AthAt5g01490
GO:0051592 response to calcium ion P
IMP
AthAt3g51860
GO:0055085 transmembrane transport P
IDA
SceS000002286
IMP
SceS000002286
GO:0070588 calcium ion transmembrane transport P
IC
SpoSPCC1795.02c

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
22208

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) SPAC521.04c GI:19114011 Q9P7B3
Saccharomyces cerevisiae (Sce) VNX1
(S000005265)		 GI:6324008 P42839
Kluyveromyces lactis (Kla) KLLA0E21109g GI:50309777
Eremothecium gossypii (Ego) AGOS_ADL189W GI:45187684
Magnaporthe grisea (Mgr) MGG_01381 GI:39951477
Neurospora crassa (Ncr) NCU05360.1 GI:32409469


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000324 fungal-type vacuole C
IDA
SceS000005265
GO:0005783 endoplasmic reticulum C
IDA
SpoSPAC521.04c
GO:0005789 endoplasmic reticulum membrane C
IDA
SceS000005265
GO:0016021 integral to membrane C
ISS
SpoSPAC521.04c
GO:0008324 cation transmembrane transporter
activity		 F
ISS
SpoSPAC521.04c
GO:0015369 calcium:hydrogen antiporter activity F
IMP
SceS000005265
GO:0015385 sodium:hydrogen antiporter activity F
IMP
SceS000005265
GO:0015386 potassium:hydrogen antiporter activity F
IMP
SceS000005265
GO:0006812 cation transport P
ISS
SpoSPAC521.04c
GO:0006813 potassium ion transport P
IMP
SceS000005265
GO:0006814 sodium ion transport P
IMP
SceS000005265
GO:0006818 hydrogen transport P
IMP
SceS000005265
GO:0034220 ion transmembrane transport P
ISS
SpoSPAC521.04c

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_7296

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago1552 ADL189W
Candida glabrata (Cgl) cgl4837 CAGL0M04147g
Cryptococcus neoformans (Cne) cne5616 179.m00478
Dictyostelium discoideum (Ddi) ddi6425 DDB0205708
Debaryomyces hansenii (Dha) dha641 DEHA0A14322g
Danio rerio (Dre) dre16655 ENSDARP00000021545
(LOC558151)
Danio rerio (Dre) dre16658 ENSDARP00000025270
(zgc:110622)		 Q503G3
Takifugu rubripes (Fru) fru26490 SINFRUP00000151279
Kluyveromyces lactis (Kla) kla3900 KLLA0E21109g
Neurospora crassa (Ncr) ncr5205 NCU05360.2
Saccharomyces cerevisiae (Sce) sce5445 YNL321W
(S000005265)
Schizosaccharomyces pombe (Spo) spo1221 SPAC521.04c Q9P7B3
Yarrowia lipolytica (Yli) yli3720 YALI0D24233g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000324 fungal-type vacuole C
IDA
SceS000005265
GO:0005783 endoplasmic reticulum C
IDA
SpoSPAC521.04c
GO:0005789 endoplasmic reticulum membrane C
IDA
SceS000005265
GO:0016021 integral to membrane C
ISS
SpoSPAC521.04c
GO:0008324 cation transmembrane transporter
activity		 F
ISS
SpoSPAC521.04c
GO:0015369 calcium:hydrogen antiporter activity F
IMP
SceS000005265
GO:0015385 sodium:hydrogen antiporter activity F
IMP
SceS000005265
GO:0015386 potassium:hydrogen antiporter activity F
IMP
SceS000005265
GO:0006812 cation transport P
ISS
SpoSPAC521.04c
GO:0006813 potassium ion transport P
IMP
SceS000005265
GO:0006814 sodium ion transport P
IMP
SceS000005265
GO:0006818 hydrogen transport P
IMP
SceS000005265
GO:0034220 ion transmembrane transport P
ISS
SpoSPAC521.04c

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC521.04c
(Q9P7B3)		 YNL321W
(S000005265)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000324 fungal-type vacuole C
IDA
SceS000005265
GO:0005783 endoplasmic reticulum C
IDA
SpoSPAC521.04c
GO:0005789 endoplasmic reticulum membrane C
IDA
SceS000005265
GO:0016021 integral to membrane C
ISS
SpoSPAC521.04c
GO:0008324 cation transmembrane transporter
activity		 F
ISS
SpoSPAC521.04c
GO:0015369 calcium:hydrogen antiporter activity F
IMP
SceS000005265
GO:0015385 sodium:hydrogen antiporter activity F
IMP
SceS000005265
GO:0015386 potassium:hydrogen antiporter activity F
IMP
SceS000005265
GO:0006812 cation transport P
ISS
SpoSPAC521.04c
GO:0006813 potassium ion transport P
IMP
SceS000005265
GO:0006814 sodium ion transport P
IMP
SceS000005265
GO:0006818 hydrogen transport P
IMP
SceS000005265
GO:0034220 ion transmembrane transport P
ISS
SpoSPAC521.04c

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