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Search term: YNR008W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name LRO1
SGD link S000005291
Alternative ID YNR008W
Description Acyltransferase that catalyzes diacylglycerol esterification; one of several acyltransferases that contribute to triglyceride synthesis; putative homolog of human lecithin cholesterol acyltransferase
Synonyms YNR008W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG2369 AC-HYP-

KOGs classification KOGs description
METABOLISM Lecithin:cholesterol acyltransferase (LCAT)/Acyl-ceramide synthase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g04010 GI:15219616
Arabidopsis thaliana (Ath) At1g27480 GI:15223526
Arabidopsis thaliana (Ath) At3g03310 GI:6017116
Arabidopsis thaliana (Ath) At3g44830 GI:15230521
Arabidopsis thaliana (Ath) At4g19860 GI:15235214
Arabidopsis thaliana (Ath) At5g13640 GI:15240676
Caenorhabditis elegans (Cel) CE06190
(WBGene00010872)		 GI:17508407 Q21515
Homo sapiens (Hsa) Hs4557892
(LCAT)		 GI:4557892 P04180
Homo sapiens (Hsa) Hs6912484
(PLA2G15)		 GI:6912484 Q8NCC3
Saccharomyces cerevisiae (Sce) YNR008w
(S000005291)		 GI:6324335 P40345
Schizosaccharomyces pombe (Spo) SPBC776.14 GI:19113122 O94680


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt3g03310
At3g44830
At4g19860
GO:0005576 extracellular region C
EXP
HsaLCAT
GO:0005615 extracellular space C
IDA
HsaLCAT
GO:0005764 lysosome C
NAS
HsaPLA2G15
GO:0005773 vacuole C
IDA
AthAt5g13640
At1g27480
GO:0005783 endoplasmic reticulum C
IDA
AthAt5g13640
SpoSPBC776.14
ISS
SpoSPBC776.14
TAS
SceS000005291
GO:0005792 microsome C
IDA
AthAt1g04010
GO:0005886 plasma membrane C
IDA
AthAt1g27480
GO:0030176 integral to endoplasmic reticulum
membrane		 C
IC
SpoSPBC776.14
GO:0034364 high-density lipoprotein particle C
IDA
HsaLCAT
GO:0004607 phosphatidylcholine-sterol O-acyltransferase
activity		 F
IDA
AthAt1g04010
HsaLCAT
ISS
AthAt1g27480
At5g13640
At3g44830
At1g04010
At4g19860
At3g03310
NAS
HsaLCAT
GO:0004622 lysophospholipase activity F
TAS
HsaPLA2G15
GO:0005515 protein binding F
IPI
HsaLCAT
GO:0005543 phospholipid binding F
TAS
HsaPLA2G15
GO:0034186 apolipoprotein A-I binding F
IPI
HsaLCAT
GO:0046027 phospholipid:diacylglycerol acyltransferase
activity		 F
IDA
AthAt5g13640
SceS000005291
SpoSPBC776.14
GO:0080095 phosphatidylethanolamine-sterol O-acyltransferase
activity		 F
IDA
AthAt1g04010
GO:0080096 phosphatidate-sterol O-acyltransferase
activity		 F
IDA
AthAt1g04010
GO:0006629 lipid metabolic process P
ISS
AthAt1g27480
At1g04010
At3g44830
At3g03310
At5g13640
At4g19860
GO:0006644 phospholipid metabolic process P
IDA
HsaLCAT
GO:0006656 phosphatidylcholine biosynthetic
process		 P
IDA
HsaLCAT
GO:0008203 cholesterol metabolic process P
IDA
HsaLCAT
GO:0009062 fatty acid catabolic process P
TAS
HsaPLA2G15
GO:0010150 leaf senescence P
IMP
AthAt1g04010
GO:0016127 sterol catabolic process P
IMP
AthAt1g04010
GO:0019432 triglyceride biosynthetic process P
IDA
SceS000005291
SpoSPBC776.14
IMP
SceS000005291
GO:0019915 lipid storage P
IC
SpoSPBC776.14
IDA
SceS000005291
IMP
CelWBGene00010872
SceS000005291
GO:0030301 cholesterol transport P
IDA
HsaLCAT
GO:0034372 very-low-density lipoprotein particle
remodeling		 P
IDA
HsaLCAT
GO:0034375 high-density lipoprotein particle
remodeling		 P
IDA
HsaLCAT
GO:0034434 sterol esterification P
IDA
AthAt1g04010
IMP
AthAt1g04010
GO:0034435 cholesterol esterification P
IDA
HsaLCAT
GO:0042632 cholesterol homeostasis P
IDA
HsaLCAT
GO:0043691 reverse cholesterol transport P
IDA
HsaLCAT
GO:0046339 diacylglycerol metabolic process P
IC
SpoSPBC776.14

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
40156

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) plh1
(SPBC776.14)		 GI:19113122 O94680
Saccharomyces cerevisiae (Sce) LRO1
(S000005291)		 GI:6324335 P40345
Kluyveromyces lactis (Kla) KLLA0F06380g GI:50310695
Eremothecium gossypii (Ego) AGOS_AFL179C GI:45198342
Magnaporthe grisea (Mgr) MGG_03560 GI:39942960
Neurospora crassa (Ncr) NCU02416.1 GI:32421497
Arabidopsis thaliana (Ath) ATPDAT GI:15240676
Oryza sativa (Osa) Os09g0444200 GI:115479409


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005773 vacuole C
IDA
AthATPDAT
GO:0005783 endoplasmic reticulum C
IDA
AthATPDAT
SpoSPBC776.14
ISS
SpoSPBC776.14
TAS
SceS000005291
GO:0030176 integral to endoplasmic reticulum
membrane		 C
IC
SpoSPBC776.14
GO:0004607 phosphatidylcholine-sterol O-acyltransferase
activity		 F
ISS
AthATPDAT
GO:0046027 phospholipid:diacylglycerol acyltransferase
activity		 F
IDA
AthATPDAT
SceS000005291
SpoSPBC776.14
GO:0006629 lipid metabolic process P
ISS
AthATPDAT
GO:0019432 triglyceride biosynthetic process P
IDA
SceS000005291
SpoSPBC776.14
IMP
SceS000005291
GO:0019915 lipid storage P
IC
SpoSPBC776.14
IDA
SceS000005291
IMP
SceS000005291
GO:0046339 diacylglycerol metabolic process P
IC
SpoSPBC776.14

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_5604

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Ashbya gossypii (Ago) ago3016 AFL179C
Arabidopsis thaliana (Ath) ath15756 At3g44830.1
Arabidopsis thaliana (Ath) ath23557 At5g13640.1
Candida glabrata (Cgl) cgl2772 CAGL0I05786g
Debaryomyces hansenii (Dha) dha2779 DEHA0D10868g
Takifugu rubripes (Fru) fru3228 SINFRUP00000159166
Gallus gallus (Gga) gga4414 ENSGALP00000002743
Homo sapiens (Hsa) hsa12379 ENSP00000264005
(LCAT)		 P04180
Kluyveromyces lactis (Kla) kla4369 KLLA0F06380g
Mus musculus (Mmu) mmu26616 ENSMUSP00000038232
(MGI:96755)		 Q8K139
Neurospora crassa (Ncr) ncr2349 NCU02416.2
Oryza sativa (Osa) osa40415 5014.m00080
Oryza sativa (Osa) osa52026 5994.m00155
Rattus norvegicus (Rno) rno14927 ENSRNOP00000026583
(RGD:2993)		 O35849
Saccharomyces cerevisiae (Sce) sce5475 YNR008W
(S000005291)
Schizosaccharomyces pombe (Spo) spo1594 SPBC776.14 O94680
Yarrowia lipolytica (Yli) yli4554 YALI0E16797g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
AthAt3g44830
GO:0005615 extracellular space C
IDA
MmuMGI:96755
ISO
MmuMGI:96755
GO:0005773 vacuole C
IDA
AthAt5g13640
GO:0005783 endoplasmic reticulum C
IDA
AthAt5g13640
SpoSPBC776.14
ISS
SpoSPBC776.14
TAS
SceS000005291
GO:0030176 integral to endoplasmic reticulum
membrane		 C
IC
SpoSPBC776.14
GO:0004607 phosphatidylcholine-sterol O-acyltransferase
activity		 F
IDA
MmuMGI:96755
ISO
MmuMGI:96755
ISS
AthAt5g13640
At3g44830
GO:0004623 phospholipase A2 activity F
ISO
MmuMGI:96755
GO:0046027 phospholipid:diacylglycerol acyltransferase
activity		 F
IDA
AthAt5g13640
SceS000005291
SpoSPBC776.14
GO:0006629 lipid metabolic process P
ISS
AthAt3g44830
At5g13640
GO:0008203 cholesterol metabolic process P
IDA
MmuMGI:96755
ISO
MmuMGI:96755
GO:0019432 triglyceride biosynthetic process P
IDA
SceS000005291
SpoSPBC776.14
IMP
SceS000005291
GO:0019915 lipid storage P
IC
SpoSPBC776.14
IDA
SceS000005291
IMP
SceS000005291
GO:0030301 cholesterol transport P
ISO
MmuMGI:96755
GO:0042157 lipoprotein metabolic process P
ISO
MmuMGI:96755
GO:0042158 lipoprotein biosynthetic process P
IDA
MmuMGI:96755
GO:0046339 diacylglycerol metabolic process P
IC
SpoSPBC776.14
GO:0046688 response to copper ion P
ISO
MmuMGI:96755
GO:0051384 response to glucocorticoid stimulus P
ISO
MmuMGI:96755

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC776.14
(O94680)		 YNR008W
(S000005291)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
SpoSPBC776.14
ISS
SpoSPBC776.14
TAS
SceS000005291
GO:0030176 integral to endoplasmic reticulum
membrane		 C
IC
SpoSPBC776.14
GO:0046027 phospholipid:diacylglycerol acyltransferase
activity		 F
IDA
SceS000005291
SpoSPBC776.14
GO:0019432 triglyceride biosynthetic process P
IDA
SceS000005291
SpoSPBC776.14
IMP
SceS000005291
GO:0019915 lipid storage P
IC
SpoSPBC776.14
IDA
SceS000005291
IMP
SceS000005291
GO:0046339 diacylglycerol metabolic process P
IC
SpoSPBC776.14

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GO info in one table:

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