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Search term: YNR017W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name TIM23
SGD link S000005300
Alternative ID YNR017W
Description Essential component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex); involved in protein import into mitochondrial matrix and inner membrane; with Tim17p, contributes to architecture and function of the import channel
Synonyms YNR017W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG3324 AC-HYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING Mitochondrial import inner membrane translocase, subunit TIM23

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At1g17530 GI:15220137
Arabidopsis thaliana (Ath) At1g72750 GI:15218593
Arabidopsis thaliana (Ath) At3g04800 GI:15229350
Caenorhabditis elegans (Cel) CE15854
(WBGene00008857)		 GI:17506651 Q9XVQ2
Homo sapiens (Hsa) Hs22053344 GI:22053344
Homo sapiens (Hsa) Hs5454122
(TIMM23)		 GI:5454122 Q9P1K1
Saccharomyces cerevisiae (Sce) YNR017w
(S000005300)		 GI:6324344 P32897
Schizosaccharomyces pombe (Spo) SPCC16A11.09c GI:19075496 Q9USM7


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
AthAt1g72750
SceS000005300
SpoSPCC16A11.09c
GO:0005743 mitochondrial inner membrane C
IDA
AthAt1g72750
At1g17530
GO:0005744 mitochondrial inner membrane presequence
translocase complex		 C
IPI
SceS000005300
ISS
AthAt1g72750
At3g04800
At1g17530
SpoSPCC16A11.09c
TAS
AthAt1g17530
GO:0005758 mitochondrial intermembrane space C
IDA
HsaTIMM23
GO:0016020 membrane C
IDA
AthAt1g72750
GO:0005515 protein binding F
IPI
HsaTIMM23
GO:0015266 protein channel activity F
IDA
SceS000005300
GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane
transporter activity		 F
ISS
AthAt3g04800
At1g72750
At1g17530
SpoSPCC16A11.09c
TAS
AthAt1g17530
GO:0030943 mitochondrion targeting sequence
binding		 F
IDA
SceS000005300
IMP
SceS000005300
GO:0000003 reproduction P
IMP
CelWBGene00008857
GO:0006626 protein targeting to mitochondrion P
TAS
AthAt1g17530
HsaTIMM23
GO:0006839 mitochondrial transport P
RCA
SceS000005300
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00008857
GO:0015031 protein transport P
ISS
AthAt1g72750
At3g04800
At1g17530
GO:0030150 protein import into mitochondrial
matrix		 P
IMP
SceS000005300
ISS
SpoSPCC16A11.09c
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00008857

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
40157

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) tim23
(SPCC16A11.09c)		 GI:19075496 Q9USM7
Saccharomyces cerevisiae (Sce) TIM23
(S000005300)		 GI:6324344 P32897
Kluyveromyces lactis (Kla) KLLA0F06050g GI:50310665
Eremothecium gossypii (Ego) AGOS_AAR070C GI:45184893
Magnaporthe grisea (Mgr) MGG_08885 GI:39954014
Neurospora crassa (Ncr) NCU00371.1 GI:32403688


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000005300
SpoSPCC16A11.09c
GO:0005744 mitochondrial inner membrane presequence
translocase complex		 C
IPI
SceS000005300
ISS
SpoSPCC16A11.09c
GO:0015266 protein channel activity F
IDA
SceS000005300
GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane
transporter activity		 F
ISS
SpoSPCC16A11.09c
GO:0030943 mitochondrion targeting sequence
binding		 F
IDA
SceS000005300
IMP
SceS000005300
GO:0006839 mitochondrial transport P
RCA
SceS000005300
GO:0030150 protein import into mitochondrial
matrix		 P
IMP
SceS000005300
ISS
SpoSPCC16A11.09c

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1459

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga12519 ENSANGP00000012211
Ashbya gossypii (Ago) ago256 AAR070C
Arabidopsis thaliana (Ath) ath1875 At1g17530.1
Arabidopsis thaliana (Ath) ath6566 At1g72750.1
Arabidopsis thaliana (Ath) ath12524 At3g04800.1
Caenorhabditis elegans (Cel) cel6426 F15D3.7
(CE15854;
WBGene00008857)
Candida glabrata (Cgl) cgl2762 CAGL0I05566g
Cryptococcus neoformans (Cne) cne500 163.m06136
Dictyostelium discoideum (Ddi) ddi9331 DDB0187006
Debaryomyces hansenii (Dha) dha934 DEHA0B05610g
Drosophila melanogaster (Dme) dme19156 CG40042-PA
Danio rerio (Dre) dre3728 ENSDARP00000022844
Takifugu rubripes (Fru) fru21633 SINFRUP00000155772
Gallus gallus (Gga) gga20154 ENSGALP00000003252
(TIMM23)
Homo sapiens (Hsa) hsa3898 ENSP00000260867
(TIMM23)		 O14925
Kluyveromyces lactis (Kla) kla4354 KLLA0F06050g
Mus musculus (Mmu) mmu7902 ENSMUSP00000013845
(MGI:1858317)		 Q8JZQ1
Mus musculus (Mmu) mmu8402 ENSMUSP00000071192
Mus musculus (Mmu) mmu2184 ENSMUSP00000075292
Mus musculus (Mmu) mmu1513 ENSMUSP00000079438
Neurospora crassa (Ncr) ncr357 NCU00371.2
Oryza sativa (Osa) osa7833 2526.m00075
Oryza sativa (Osa) osa8182 2539.m00121
Oryza sativa (Osa) osa294 37.m00058
Oryza sativa (Osa) osa64200 6794.m00077
Oryza sativa (Osa) osa70095 6977.m00170
Plasmodium falciparum (Pfa) pfa3816 PF13_0300
Rattus norvegicus (Rno) rno25167 ENSRNOP00000007325
Rattus norvegicus (Rno) rno12040 ENSRNOP00000026932
(RGD:3863)		 O35093
Rattus norvegicus (Rno) rno25102 ENSRNOP00000040401
(RGD:1559672)
Rattus norvegicus (Rno) rno19243 ENSRNOP00000051189
Saccharomyces cerevisiae (Sce) sce5484 YNR017W
(S000005300)
Schizosaccharomyces pombe (Spo) spo2857 SPCC16A11.09c Q9USM7
Yarrowia lipolytica (Yli) yli6550 YALI0F29183g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
AthAt1g72750
MmuMGI:1858317
SceS000005300
SpoSPCC16A11.09c
GO:0005743 mitochondrial inner membrane C
IDA
AthAt1g72750
At1g17530
MmuMGI:1858317
ISO
MmuMGI:1858317
GO:0005744 mitochondrial inner membrane presequence
translocase complex		 C
IPI
SceS000005300
ISO
MmuMGI:1858317
ISS
AthAt1g72750
At3g04800
At1g17530
PfaPF13_0300
SpoSPCC16A11.09c
TAS
AthAt1g17530
GO:0005758 mitochondrial intermembrane space C
ISO
MmuMGI:1858317
GO:0016020 membrane C
IDA
AthAt1g72750
GO:0015266 protein channel activity F
IDA
SceS000005300
GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane
transporter activity		 F
ISO
MmuMGI:1858317
ISS
AthAt3g04800
At1g72750
At1g17530
SpoSPCC16A11.09c
TAS
AthAt1g17530
GO:0030943 mitochondrion targeting sequence
binding		 F
IDA
SceS000005300
IMP
SceS000005300
GO:0000003 reproduction P
IMP
CelWBGene00008857
GO:0006626 protein targeting to mitochondrion P
ISS
PfaPF13_0300
TAS
AthAt1g17530
GO:0006839 mitochondrial transport P
RCA
SceS000005300
GO:0006886 intracellular protein transport P
ISO
MmuMGI:1858317
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00008857
GO:0015031 protein transport P
ISS
AthAt1g72750
At3g04800
At1g17530
GO:0030150 protein import into mitochondrial
matrix		 P
IMP
SceS000005300
ISS
SpoSPCC16A11.09c
GO:0040035 hermaphrodite genitalia development P
IMP
CelWBGene00008857

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPCC16A11.09c
(Q9USM7)		 YNR017W
(S000005300)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005739 mitochondrion C
IDA
SceS000005300
SpoSPCC16A11.09c
GO:0005744 mitochondrial inner membrane presequence
translocase complex		 C
IPI
SceS000005300
ISS
SpoSPCC16A11.09c
GO:0015266 protein channel activity F
IDA
SceS000005300
GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane
transporter activity		 F
ISS
SpoSPCC16A11.09c
GO:0030943 mitochondrion targeting sequence
binding		 F
IDA
SceS000005300
IMP
SceS000005300
GO:0006839 mitochondrial transport P
RCA
SceS000005300
GO:0030150 protein import into mitochondrial
matrix		 P
IMP
SceS000005300
ISS
SpoSPCC16A11.09c

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GO info in one table:

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