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Search term: YNR031C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name SSK2
SGD link S000005314
Alternative ID YNR031C
Description MAP kinase kinase kinase of the HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress
Synonyms YNR031C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG4645 --DHYP-

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING MAPKKK (MAP kinase kinase kinase) SSK2 and related serine/threonine protein kinases

Species KOG link NCBI link UniProt link
Drosophila melanogaster (Dme) 7300435 GI:7300435
Homo sapiens (Hsa) Hs5803088 GI:5803088
Homo sapiens (Hsa) Hs6031180 GI:6031180
Saccharomyces cerevisiae (Sce) YCR073c
(S000000669)		 GI:10383805 P25390
Saccharomyces cerevisiae (Sce) YNR031c
(S000005314)		 GI:6324358 P53599
Schizosaccharomyces pombe (Spo) SPAC1006.09 GI:19115768 O74304
Schizosaccharomyces pombe (Spo) SPAC9G1.02 GI:19114469 O14299


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
SceS000000669
SpoSPAC1006.09
GO:0005737 cytoplasm C
IDA
SpoSPAC9G1.02
GO:0005829 cytosol C
IDA
SceS000005314
SpoSPAC9G1.02
GO:0005934 cellular bud tip C
IDA
SceS000005314
GO:0005935 cellular bud neck C
IDA
SceS000005314
GO:0004709 MAP kinase kinase kinase activity F
IGI
SpoSPAC1006.09
TAS
SceS000005314
S000000669
SpoSPAC9G1.02
GO:0005515 protein binding F
IGI
SpoSPAC1006.09
GO:0005524 ATP binding F
ISS
SpoSPAC1006.09
SPAC9G1.02
GO:0000165 MAPKKK cascade P
IC
SpoSPAC9G1.02
GO:0000168 activation of MAPKK activity involved in
osmosensory signaling pathway		 P
TAS
SceS000000669
S000005314
GO:0000186 activation of MAPKK activity P
IGI
SpoSPAC1006.09
GO:0006468 protein amino acid phosphorylation P
IC
SpoSPAC1006.09
IGI
SpoSPAC9G1.02
TAS
SceS000000669
S000005314
GO:0006970 response to osmotic stress P
IGI
SceS000005314
IMP
SceS000005314
GO:0007231 osmosensory signaling pathway P
TAS
SceS000000669
S000005314
GO:0007243 intracellular protein kinase cascade P
RCA
SceS000000669
GO:0007346 regulation of mitotic cell cycle P
IMP
SpoSPAC1006.09
SPAC9G1.02
GO:0030036 actin cytoskeleton organization P
IDA
SceS000005314
GO:0031098 stress-activated protein kinase signaling
cascade		 P
IGI
SpoSPAC9G1.02
SPAC1006.09
GO:0051403 stress-activated MAPK cascade P
NAS
SpoSPAC9G1.02
GO:0061161 positive regulation of establishment of bipolar
cell polarity resulting in cell
shape		 P
IMP
SpoSPAC1006.09
SPAC9G1.02

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
81791

Species Gene ID NCBI link UniProt link
Schizosaccharomyces pombe (Spo) SPAPJ730.01 GI:63054663
Saccharomyces cerevisiae (Sce) SSK2
(S000005314)		 GI:6324358 P53599
Kluyveromyces lactis (Kla) KLLA0C08525g GI:50305241
Eremothecium gossypii (Ego) AGOS_AER264C GI:45190867


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005829 cytosol C
IDA
SceS000005314
GO:0005934 cellular bud tip C
IDA
SceS000005314
GO:0005935 cellular bud neck C
IDA
SceS000005314
GO:0004709 MAP kinase kinase kinase activity F
TAS
SceS000005314
GO:0000168 activation of MAPKK activity involved in
osmosensory signaling pathway		 P
TAS
SceS000005314
GO:0006468 protein amino acid phosphorylation P
TAS
SceS000005314
GO:0006970 response to osmotic stress P
IGI
SceS000005314
IMP
SceS000005314
GO:0007231 osmosensory signaling pathway P
TAS
SceS000005314
GO:0030036 actin cytoskeleton organization P
IDA
SceS000005314

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_3404

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga4538 ENSANGP00000014818
Ashbya gossypii (Ago) ago2766 AER264C
Caenorhabditis elegans (Cel) cel467 B0414.7a
(CE07737;
WBGene00003472)
Caenorhabditis elegans (Cel) cel468 B0414.7b
(CE27573)
Candida glabrata (Cgl) cgl5128 CAGL0M10791g
Debaryomyces hansenii (Dha) dha1864 DEHA0C09823g
Drosophila melanogaster (Dme) dme13291 CG7717-PA
(FBgn0024329)
Drosophila melanogaster (Dme) dme13292 CG7717-PB
(FBgn0024329)
Danio rerio (Dre) dre4565 ENSDARP00000028066
Takifugu rubripes (Fru) fru27584 SINFRUP00000148229
Takifugu rubripes (Fru) fru27583 SINFRUP00000148230
Gallus gallus (Gga) gga15129 ENSGALP00000018870
(MAP3K4)
Gallus gallus (Gga) gga15130 ENSGALP00000018873
Homo sapiens (Hsa) hsa28018 ENSP00000265125
Homo sapiens (Hsa) hsa28017 ENSP00000297332
(MAP3K4)		 Q9Y6R4-1
Kluyveromyces lactis (Kla) kla1579 KLLA0C08525g
Mus musculus (Mmu) mmu10821 ENSMUSP00000014570
Mus musculus (Mmu) mmu10822 ENSMUSP00000074170
(MGI:1346875)		 Q3UZV9
Neurospora crassa (Ncr) ncr2975 NCU03071.2
Rattus norvegicus (Rno) rno467 ENSRNOP00000023496
(RGD:1311192)
Rattus norvegicus (Rno) rno468 ENSRNOP00000023503
(RGD:1311192)
Saccharomyces cerevisiae (Sce) sce729 YCR073C
(S000000669)
Saccharomyces cerevisiae (Sce) sce5498 YNR031C
(S000005314)
Schizosaccharomyces pombe (Spo) spo872 SPAC1006.09 O74304
Schizosaccharomyces pombe (Spo) spo1589 SPAC9G1.02 O14299
Yarrowia lipolytica (Yli) yli182 YALI0A05247g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
SceS000000669
SpoSPAC1006.09
GO:0005737 cytoplasm C
IDA
MmuMGI:1346875
SpoSPAC9G1.02
GO:0005829 cytosol C
IDA
SceS000005314
SpoSPAC9G1.02
GO:0005934 cellular bud tip C
IDA
SceS000005314
GO:0005935 cellular bud neck C
IDA
SceS000005314
GO:0004672 protein kinase activity F
IDA
MmuMGI:1346875
GO:0004702 receptor signaling protein serine/threonine kinase
activity		 F
NAS
DmeFBgn0024329
GO:0004709 MAP kinase kinase kinase activity F
IDA
DmeFBgn0024329
IGI
SpoSPAC1006.09
NAS
DmeFBgn0024329
TAS
DmeFBgn0024329
SceS000005314
S000000669
SpoSPAC9G1.02
GO:0005515 protein binding F
IGI
SpoSPAC1006.09
IPI
MmuMGI:1346875
GO:0005524 ATP binding F
ISS
SpoSPAC1006.09
SPAC9G1.02
GO:0000165 MAPKKK cascade P
IC
SpoSPAC9G1.02
IDA
DmeFBgn0024329
GO:0000168 activation of MAPKK activity involved in
osmosensory signaling pathway		 P
TAS
SceS000000669
S000005314
GO:0000186 activation of MAPKK activity P
IGI
SpoSPAC1006.09
GO:0002385 mucosal immune response P
IMP
DmeFBgn0024329
GO:0006468 protein amino acid phosphorylation P
IC
SpoSPAC1006.09
IDA
DmeFBgn0024329
IGI
SpoSPAC9G1.02
NAS
DmeFBgn0024329
TAS
DmeFBgn0024329
SceS000000669
S000005314
GO:0006950 response to stress P
IDA
DmeFBgn0024329
IMP
DmeFBgn0024329
GO:0006970 response to osmotic stress P
IGI
SceS000005314
IMP
SceS000005314
GO:0006979 response to oxidative stress P
IMP
DmeFBgn0024329
GO:0007231 osmosensory signaling pathway P
TAS
SceS000000669
S000005314
GO:0007243 intracellular protein kinase cascade P
IDA
MmuMGI:1346875
RCA
SceS000000669
GO:0007346 regulation of mitotic cell cycle P
IMP
SpoSPAC1006.09
SPAC9G1.02
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00003472
GO:0016246 RNA interference P
IMP
CelWBGene00003472
GO:0030036 actin cytoskeleton organization P
IDA
SceS000005314
GO:0031098 stress-activated protein kinase signaling
cascade		 P
IGI
SpoSPAC9G1.02
SPAC1006.09
GO:0043507 positive regulation of JUN kinase
activity		 P
IDA
MmuMGI:1346875
IMP
MmuMGI:1346875
GO:0051403 stress-activated MAPK cascade P
NAS
SpoSPAC9G1.02
GO:0061161 positive regulation of establishment of bipolar
cell polarity resulting in cell
shape		 P
IMP
SpoSPAC1006.09
SPAC9G1.02

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Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPAC9G1.02
(O14299)		 YNR031C
(S000005314)
SPAC1006.09
(O74304)		 YNR031C
(S000005314)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005575 cellular_component C
ND
SpoSPAC1006.09
GO:0005737 cytoplasm C
IDA
SpoSPAC9G1.02
GO:0005829 cytosol C
IDA
SceS000005314
SpoSPAC9G1.02
GO:0005934 cellular bud tip C
IDA
SceS000005314
GO:0005935 cellular bud neck C
IDA
SceS000005314
GO:0004709 MAP kinase kinase kinase activity F
IGI
SpoSPAC1006.09
TAS
SceS000005314
SpoSPAC9G1.02
GO:0005515 protein binding F
IGI
SpoSPAC1006.09
GO:0005524 ATP binding F
ISS
SpoSPAC1006.09
SPAC9G1.02
GO:0000165 MAPKKK cascade P
IC
SpoSPAC9G1.02
GO:0000168 activation of MAPKK activity involved in
osmosensory signaling pathway		 P
TAS
SceS000005314
GO:0000186 activation of MAPKK activity P
IGI
SpoSPAC1006.09
GO:0006468 protein amino acid phosphorylation P
IC
SpoSPAC1006.09
IGI
SpoSPAC9G1.02
TAS
SceS000005314
GO:0006970 response to osmotic stress P
IGI
SceS000005314
IMP
SceS000005314
GO:0007231 osmosensory signaling pathway P
TAS
SceS000005314
GO:0007346 regulation of mitotic cell cycle P
IMP
SpoSPAC1006.09
SPAC9G1.02
GO:0030036 actin cytoskeleton organization P
IDA
SceS000005314
GO:0031098 stress-activated protein kinase signaling
cascade		 P
IGI
SpoSPAC9G1.02
SPAC1006.09
GO:0051403 stress-activated MAPK cascade P
NAS
SpoSPAC9G1.02
GO:0061161 positive regulation of establishment of bipolar
cell polarity resulting in cell
shape		 P
IMP
SpoSPAC1006.09
SPAC9G1.02

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Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk