YOGY Home YOGY Help

Search term: YNR050C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name LYS9
SGD link S000005333
Alternative ID YNR050C
Description Saccharopine dehydrogenase (NADP+, L-glutamate-forming); catalyzes the formation of saccharopine from alpha-aminoadipate 6-semialdehyde, the seventh step in lysine biosynthesis pathway; exhibits genetic and physical interactions with TRM112
Synonyms YNR050C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0172 ACDHYP-

KOGs classification KOGs description
METABOLISM Lysine-ketoglutarate reductase/saccharopine dehydrogenase

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At4g33150 GI:7488325
Caenorhabditis elegans (Cel) CE18095
(WBGene00019819)		 GI:17541738 O44503
Drosophila melanogaster (Dme) 7297296 GI:19920892
Homo sapiens (Hsa) Hs13027640
(AASS)		 GI:13027640 Q9UDR5
Saccharomyces cerevisiae (Sce) YIR034c
(S000001473)		 GI:6322225 P38998
Saccharomyces cerevisiae (Sce) YNR050c
(S000005333)		 GI:6324378 P38999
Schizosaccharomyces pombe (Spo) SPAC227.18 GI:19113884 Q09694
Schizosaccharomyces pombe (Spo) SPBC3B8.03 GI:19113203 O59711
Arabidopsis thaliana (Ath) At4g33150 GI:7488325
Caenorhabditis elegans (Cel) CE18095
(WBGene00019819)		 GI:17541738 O44503
Drosophila melanogaster (Dme) 7297296 GI:19920892
Homo sapiens (Hsa) Hs13027640
(AASS)		 GI:13027640 Q9UDR5
Saccharomyces cerevisiae (Sce) YIR034c
(S000001473)		 GI:6322225 P38998
Saccharomyces cerevisiae (Sce) YNR050c
(S000005333)		 GI:6324378 P38999
Schizosaccharomyces pombe (Spo) SPAC227.18 GI:19113884 Q09694
Schizosaccharomyces pombe (Spo) SPBC3B8.03 GI:19113203 O59711
Arabidopsis thaliana (Ath) At4g33150 GI:7488325
Caenorhabditis elegans (Cel) CE18095
(WBGene00019819)		 GI:17541738 O44503
Drosophila melanogaster (Dme) 7297296 GI:19920892
Homo sapiens (Hsa) Hs13027640
(AASS)		 GI:13027640 Q9UDR5
Saccharomyces cerevisiae (Sce) YIR034c
(S000001473)		 GI:6322225 P38998
Saccharomyces cerevisiae (Sce) YNR050c
(S000005333)		 GI:6324378 P38999
Schizosaccharomyces pombe (Spo) SPAC227.18 GI:19113884 Q09694
Schizosaccharomyces pombe (Spo) SPBC3B8.03 GI:19113203 O59711


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
AthAt4g33150
SceS000005333
S000001473
SpoSPAC227.18
ISS
SpoSPAC227.18
SPBC3B8.03
GO:0005739 mitochondrion C
TAS
HsaAASS
GO:0005829 cytosol C
IDA
SpoSPBC3B8.03
GO:0004753 saccharopine dehydrogenase activity F
IDA
AthAt4g33150
GO:0004754 saccharopine dehydrogenase (NAD+,
L-lysine-forming) activity		 F
IDA
SceS000001473
ISS
SpoSPAC227.18
GO:0004755 saccharopine dehydrogenase (NADP+,
L-glutamate-forming) activity		 F
IDA
SceS000005333
ISS
SpoSPBC3B8.03
GO:0047131 saccharopine dehydrogenase (NAD+,
L-glutamate-forming) activity		 F
NAS
HsaAASS
GO:0006082 organic acid metabolic process P
RCA
SceS000001473
GO:0006414 translational elongation P
RCA
SceS000001473
GO:0006519 cellular amino acid and derivative metabolic
process		 P
RCA
SceS000001473
GO:0006554 lysine catabolic process P
NAS
HsaAASS
GO:0006725 cellular aromatic compound metabolic
process		 P
RCA
SceS000001473
GO:0006807 nitrogen compound metabolic process P
RCA
SceS000001473
GO:0009085 lysine biosynthetic process P
IMP
SceS000001473
SpoSPBC3B8.03
GO:0019477 L-lysine catabolic process P
IDA
AthAt4g33150
GO:0019878 lysine biosynthetic process via aminoadipic
acid		 P
IMP
SceS000005333
SpoSPAC227.18
NAS
SceS000001473
TAS
SceS000001473
GO:0051262 protein tetramerization P
TAS
HsaAASS

Back to the top

HomoloGene results:

HomoloGene cluster Phylogenetic pattern
4212

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) AASS GI:13027640 Q9UDR5
Pan troglodytes (Ptr) AASS GI:114615673
Canis familiaris (Cfa) AASS GI:73976657
Mus musculus (Mmu) Aass
(MGI:1353573)		 GI:31980703 Q3UEQ9
Rattus norvegicus (Rno) Aass GI:109471811
Gallus gallus (Gga) AASS GI:118082239
Drosophila melanogaster (Dme) CG7144
(FBgn0025687)		 GI:23397395
Anopheles gambiae (Aga) AgaP_AGAP008632 GI:158293377
Caenorhabditis elegans (Cel) dehydrogenase GI:17541738 O44503
Schizosaccharomyces pombe (Spo) SPBC3B8.03 GI:19113203 O59711
Saccharomyces cerevisiae (Sce) LYS9
(S000005333)		 GI:6324378 P38999
Kluyveromyces lactis (Kla) KLLA0C18744g GI:50306147
Magnaporthe grisea (Mgr) MGG_08564 GI:39946672
Neurospora crassa (Ncr) NCU03748.1 GI:32404874


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000005333
ISS
SpoSPBC3B8.03
GO:0005739 mitochondrion C
TAS
HsaAASS
GO:0005829 cytosol C
IDA
SpoSPBC3B8.03
GO:0004754 saccharopine dehydrogenase (NAD+,
L-lysine-forming) activity		 F
ISS
DmeFBgn0025687
GO:0004755 saccharopine dehydrogenase (NADP+,
L-glutamate-forming) activity		 F
IDA
SceS000005333
ISS
SpoSPBC3B8.03
GO:0047131 saccharopine dehydrogenase (NAD+,
L-glutamate-forming) activity		 F
NAS
HsaAASS
GO:0006554 lysine catabolic process P
NAS
HsaAASS
GO:0009085 lysine biosynthetic process P
IMP
SpoSPBC3B8.03
GO:0019477 L-lysine catabolic process P
IDA
MmuMGI:1353573
GO:0019878 lysine biosynthetic process via aminoadipic
acid		 P
IMP
SceS000005333
GO:0031060 regulation of histone methylation P
IDA
DmeFBgn0025687
GO:0034969 histone arginine methylation P
IDA
DmeFBgn0025687
GO:0051262 protein tetramerization P
TAS
HsaAASS

Back to the top

OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_2450

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga10651 ENSANGP00000013147
Ashbya gossypii (Ago) ago708 ABR116C
Arabidopsis thaliana (Ath) ath21429 At4g33150.1
Arabidopsis thaliana (Ath) ath21430 At4g33150.2
Caenorhabditis elegans (Cel) cel13180 R02D3.1
(CE18095;
WBGene00019819)
Candida glabrata (Cgl) cgl566 CAGL0C03443g
Cryptococcus neoformans (Cne) cne2018 181.m07999
Dictyostelium discoideum (Ddi) ddi9933 DDB0186419
Dictyostelium discoideum (Ddi) ddi9898 DDB0218638
Debaryomyces hansenii (Dha) dha5230 DEHA0F18865g
Drosophila melanogaster (Dme) dme1303 CG7144-PA
(FBgn0025687)
Danio rerio (Dre) dre16465 ENSDARP00000031765
Danio rerio (Dre) dre27978 ENSDARP00000044175
Takifugu rubripes (Fru) fru22655 SINFRUP00000146943
Takifugu rubripes (Fru) fru22656 SINFRUP00000168547
Takifugu rubripes (Fru) fru22657 SINFRUP00000175064
Gallus gallus (Gga) gga269 ENSGALP00000014543
(AASS)
Gallus gallus (Gga) gga270 ENSGALP00000014544
Gallus gallus (Gga) gga271 ENSGALP00000014545
Homo sapiens (Hsa) hsa29339 ENSP00000222418
Homo sapiens (Hsa) hsa29340 ENSP00000351834
(AASS)		 C9JZ35
Kluyveromyces lactis (Kla) kla2034 KLLA0C18744g
Mus musculus (Mmu) mmu21489 ENSMUSP00000031707
(MGI:1353573)		 Q99K67
Mus musculus (Mmu) mmu21490 ENSMUSP00000074812
Neurospora crassa (Ncr) ncr3638 NCU03748.2
Oryza sativa (Osa) osa6838 2503.m00163
Oryza sativa (Osa) osa6840 2503.m00164
Oryza sativa (Osa) osa28542 4248.m00150
Saccharomyces cerevisiae (Sce) sce5519 YNR050C
(S000005333)
Schizosaccharomyces pombe (Spo) spo3789 SPBC3B8.03 O59711
Yarrowia lipolytica (Yli) yli3664 YALI0D22891g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
AthAt4g33150
SceS000005333
ISS
SpoSPBC3B8.03
GO:0005829 cytosol C
IDA
SpoSPBC3B8.03
GO:0004753 saccharopine dehydrogenase activity F
IDA
AthAt4g33150
GO:0004754 saccharopine dehydrogenase (NAD+,
L-lysine-forming) activity		 F
ISS
DmeFBgn0025687
GO:0004755 saccharopine dehydrogenase (NADP+,
L-glutamate-forming) activity		 F
IDA
SceS000005333
ISS
SpoSPBC3B8.03
GO:0009085 lysine biosynthetic process P
IMP
SpoSPBC3B8.03
GO:0019477 L-lysine catabolic process P
IDA
AthAt4g33150
MmuMGI:1353573
GO:0019878 lysine biosynthetic process via aminoadipic
acid		 P
IMP
SceS000005333
GO:0031060 regulation of histone methylation P
IDA
DmeFBgn0025687
GO:0034969 histone arginine methylation P
IDA
DmeFBgn0025687

Back to the top

Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC3B8.03
(O59711)		 YNR050C
(S000005333)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005737 cytoplasm C
IDA
SceS000005333
ISS
SpoSPBC3B8.03
GO:0005829 cytosol C
IDA
SpoSPBC3B8.03
GO:0004755 saccharopine dehydrogenase (NADP+,
L-glutamate-forming) activity		 F
IDA
SceS000005333
ISS
SpoSPBC3B8.03
GO:0009085 lysine biosynthetic process P
IMP
SpoSPBC3B8.03
GO:0019878 lysine biosynthetic process via aminoadipic
acid		 P
IMP
SceS000005333

Back to the top
YOGY Home YOGY Help

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk