YOGY Home YOGY Help

Search term: YOL002C

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name IZH2
SGD link S000005362
Alternative ID YOL002C
Description Plasma membrane protein involved in zinc homeostasis and osmotin-induced apoptosis; transcription regulated by Zap1p, zinc and fatty acid levels; similar to mammalian adiponectins; deletion increases sensitivity to elevated zinc
Synonyms YOL002C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0748 ACDHYPE

KOGs classification KOGs description
POORLY CHARACTERIZEDCELLULAR PROCESSES AND SIGNALING Predicted membrane proteins, contain hemolysin III domain

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At2g24150 GI:15224096
Arabidopsis thaliana (Ath) At2g40710 GI:15226736
Arabidopsis thaliana (Ath) At4g30850 GI:15234912
Arabidopsis thaliana (Ath) At4g37680 GI:15235657
Arabidopsis thaliana (Ath) At4g38290 GI:15233780
Arabidopsis thaliana (Ath) At4g38320 GI:15233813
Arabidopsis thaliana (Ath) At5g20270 GI:15241302
Caenorhabditis elegans (Cel) CE12110 GI:17562502
Caenorhabditis elegans (Cel) CE24200 GI:17555616
Caenorhabditis elegans (Cel) CE24569 GI:17543938
Caenorhabditis elegans (Cel) CE27653
(WBGene00015476)		 GI:17550162
Caenorhabditis elegans (Cel) CE27848
(WBGene00016610)		 GI:17539162 Q94177
Drosophila melanogaster (Dme) 7299917 GI:7299917 Q9VFG7
Drosophila melanogaster (Dme) 7301711 GI:7301711
Drosophila melanogaster (Dme) 7301718 GI:7301718
Homo sapiens (Hsa) Hs13375715 GI:13375715
Homo sapiens (Hsa) Hs13376351 GI:13376351
Homo sapiens (Hsa) Hs17446780 GI:17446780
Homo sapiens (Hsa) Hs17487953 GI:17487953
Homo sapiens (Hsa) Hs18549110 GI:18549110
Homo sapiens (Hsa) Hs18556998 GI:18556998
Homo sapiens (Hsa) Hs19115960
(PAQR8)		 GI:19115960 Q8TEZ7
Homo sapiens (Hsa) Hs21361519 GI:16166606
Homo sapiens (Hsa) Hs22050062 GI:22050062
Homo sapiens (Hsa) Hs8923183 GI:8923183
Homo sapiens (Hsa) HsM7705761 GI:7705761
Saccharomyces cerevisiae (Sce) YDR492w
(S000002900)		 GI:6320699 Q03419
Saccharomyces cerevisiae (Sce) YLR023c
(S000004013)		 GI:6323051 Q07959
Saccharomyces cerevisiae (Sce) YOL002c
(S000005362)		 GI:6324572
Saccharomyces cerevisiae (Sce) YOL101c
(S000005461)		 GI:6324471 Q99393
Schizosaccharomyces pombe (Spo) SPAC30D11.11 GI:19114118 Q09910
Schizosaccharomyces pombe (Spo) SPBC12C2.09c GI:19112805 Q09749
Encephalitozoon cuniculi (Ecu) ECU06g1500 GI:19074401 Q8SV70
Arabidopsis thaliana (Ath) At2g24150 GI:15224096
Arabidopsis thaliana (Ath) At2g40710 GI:15226736
Arabidopsis thaliana (Ath) At4g30850 GI:15234912
Arabidopsis thaliana (Ath) At4g37680 GI:15235657
Arabidopsis thaliana (Ath) At4g38290 GI:15233780
Arabidopsis thaliana (Ath) At4g38320 GI:15233813
Arabidopsis thaliana (Ath) At5g20270 GI:15241302
Caenorhabditis elegans (Cel) CE12110 GI:17562502
Caenorhabditis elegans (Cel) CE24200 GI:17555616
Caenorhabditis elegans (Cel) CE24569 GI:17543938
Caenorhabditis elegans (Cel) CE27653
(WBGene00015476)		 GI:17550162
Caenorhabditis elegans (Cel) CE27848
(WBGene00016610)		 GI:17539162 Q94177
Drosophila melanogaster (Dme) 7299917 GI:7299917 Q9VFG7
Drosophila melanogaster (Dme) 7301711 GI:7301711
Drosophila melanogaster (Dme) 7301718 GI:7301718
Homo sapiens (Hsa) Hs13375715 GI:13375715
Homo sapiens (Hsa) Hs13376351 GI:13376351
Homo sapiens (Hsa) Hs17446780 GI:17446780
Homo sapiens (Hsa) Hs17487953 GI:17487953
Homo sapiens (Hsa) Hs18549110 GI:18549110
Homo sapiens (Hsa) Hs18556998 GI:18556998
Homo sapiens (Hsa) Hs19115960
(PAQR8)		 GI:19115960 Q8TEZ7
Homo sapiens (Hsa) Hs21361519 GI:16166606
Homo sapiens (Hsa) Hs22050062 GI:22050062
Homo sapiens (Hsa) Hs8923183 GI:8923183
Homo sapiens (Hsa) HsM7705761 GI:7705761
Saccharomyces cerevisiae (Sce) YDR492w
(S000002900)		 GI:6320699 Q03419
Saccharomyces cerevisiae (Sce) YLR023c
(S000004013)		 GI:6323051 Q07959
Saccharomyces cerevisiae (Sce) YOL002c
(S000005362)		 GI:6324572
Saccharomyces cerevisiae (Sce) YOL101c
(S000005461)		 GI:6324471 Q99393
Schizosaccharomyces pombe (Spo) SPAC30D11.11 GI:19114118 Q09910
Schizosaccharomyces pombe (Spo) SPBC12C2.09c GI:19112805 Q09749
Encephalitozoon cuniculi (Ecu) ECU06g1500 GI:19074401 Q8SV70


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
SceS000004013
S000002900
SpoSPAC30D11.11
ISS
SpoSPBC12C2.09c
SPAC30D11.11
GO:0005789 endoplasmic reticulum membrane C
IC
SpoSPBC12C2.09c
SPAC30D11.11
GO:0005794 Golgi apparatus C
IDA
SpoSPAC30D11.11
GO:0005886 plasma membrane C
IDA
SceS000005362
GO:0016020 membrane C
ISS
SceS000005461
S000005362
S000004013
S000002900
SpoSPAC30D11.11
SPBC12C2.09c
TAS
SceS000002900
S000004013
S000005461
GO:0016021 integral to membrane C
ISM
SceS000005461
ISS
SceS000005362
GO:0003674 molecular_function F
ND
AthAt2g40710
At4g38290
GO:0004872 receptor activity F
ISS
AthAt4g37680
At4g38320
At4g30850
At2g24150
At5g20270
GO:0005515 protein binding F
IPI
SceS000005362
GO:0046872 metal ion binding F
ISS
SceS000002900
S000004013
S000005362
S000005461
SpoSPAC30D11.11
SPBC12C2.09c
GO:0006414 translational elongation P
RCA
SceS000005461
S000005362
GO:0006629 lipid metabolic process P
ISS
SpoSPBC12C2.09c
GO:0006882 cellular zinc ion homeostasis P
IMP
SceS000002900
S000005461
S000004013
S000005362
ISS
SceS000005461
S000004013
S000002900
S000005362
SpoSPBC12C2.09c
SPAC30D11.11
GO:0006979 response to oxidative stress P
IMP
AthAt2g24150
GO:0008150 biological_process P
ND
AthAt4g38290
At2g40710
GO:0009636 response to toxin P
IMP
SceS000005362
GO:0009651 response to salt stress P
IEP
AthAt5g20270
GO:0009725 response to hormone stimulus P
IEP
AthAt5g20270
At2g24150
At4g38320
At4g30850
At4g37680
GO:0009744 response to sucrose stimulus P
IEP
AthAt4g30850
At5g20270
At4g37680
At4g38320
At2g24150
GO:0010043 response to zinc ion P
ISS
SceS000002900
S000005362
SpoSPBC12C2.09c
GO:0044255 cellular lipid metabolic process P
TAS
SceS000002900
S000005362
S000005461

Back to the top

HomoloGene results:

HomoloGene cluster Phylogenetic pattern
56119

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) ADIPOR2 GI:38261973
Pan troglodytes (Ptr) ADIPOR2 GI:114642805
Canis familiaris (Cfa) ADIPOR2 GI:73997564
Mus musculus (Mmu) Adipor2
(MGI:93830)		 GI:39841016 Q53YY3
Rattus norvegicus (Rno) Adipor2
(RGD:1307891)		 GI:83816891
Gallus gallus (Gga) ADIPOR2 GI:56119026
Schizosaccharomyces pombe (Spo) SPBC12C2.09c GI:19112805 Q09749
Saccharomyces cerevisiae (Sce) IZH2
(S000005362)		 GI:27808716
Kluyveromyces lactis (Kla) KLLA0D01331g GI:50306311
Eremothecium gossypii (Ego) AGOS_ACL002C GI:45185686
Magnaporthe grisea (Mgr) MGG_05072 GI:39940336
Neurospora crassa (Ncr) NCU04987.1 GI:32407672
Oryza sativa (Osa) Os12g0511200 GI:115488760


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
ISS
SpoSPBC12C2.09c
GO:0005789 endoplasmic reticulum membrane C
IC
SpoSPBC12C2.09c
GO:0005886 plasma membrane C
IDA
SceS000005362
GO:0016020 membrane C
ISS
SceS000005362
SpoSPBC12C2.09c
GO:0016021 integral to membrane C
ISS
SceS000005362
GO:0004872 receptor activity F
IDA
MmuMGI:93830
GO:0005515 protein binding F
IPI
MmuMGI:93830
SceS000005362
GO:0042562 hormone binding F
ISS
HsaADIPOR2
MmuMGI:93830
GO:0042802 identical protein binding F
IDA
MmuMGI:93830
GO:0046872 metal ion binding F
ISS
SceS000005362
SpoSPBC12C2.09c
GO:0046982 protein heterodimerization activity F
IPI
MmuMGI:93830
GO:0006414 translational elongation P
RCA
SceS000005362
GO:0006629 lipid metabolic process P
ISS
SpoSPBC12C2.09c
GO:0006882 cellular zinc ion homeostasis P
IMP
SceS000005362
ISS
SceS000005362
SpoSPBC12C2.09c
GO:0007165 signal transduction P
IDA
MmuMGI:93830
GO:0009636 response to toxin P
IMP
SceS000005362
GO:0009755 hormone-mediated signaling pathway P
ISS
HsaADIPOR2
MmuMGI:93830
GO:0010043 response to zinc ion P
ISS
SceS000005362
SpoSPBC12C2.09c
GO:0019395 fatty acid oxidation P
ISS
HsaADIPOR2
MmuMGI:93830
GO:0030308 negative regulation of cell growth P
ISO
MmuMGI:93830
GO:0044255 cellular lipid metabolic process P
TAS
SceS000005362
GO:0046326 positive regulation of glucose
import		 P
ISO
MmuMGI:93830

Back to the top

OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_887

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga7039 ENSANGP00000012224
Ashbya gossypii (Ago) ago1047 ACL002C
Ashbya gossypii (Ago) ago3529 AFR337W
Arabidopsis thaliana (Ath) ath9327 At2g24150.1
Arabidopsis thaliana (Ath) ath21145 At4g30850.1
Arabidopsis thaliana (Ath) ath21146 At4g30850.2
Arabidopsis thaliana (Ath) ath21951 At4g37680.1
Arabidopsis thaliana (Ath) ath22024 At4g38320.1
Arabidopsis thaliana (Ath) ath24310 At5g20270.1
Caenorhabditis elegans (Cel) cel3945 C43G2.1
(CE27848;
WBGene00016610)
Caenorhabditis elegans (Cel) cel18125 Y32H12A.5
(CE35070;
WBGene00021313)
Candida glabrata (Cgl) cgl1052 CAGL0E02519g
Candida glabrata (Cgl) cgl1822 CAGL0G04631g
Dictyostelium discoideum (Ddi) ddi11051 DDB0191761
Debaryomyces hansenii (Dha) dha211 DEHA0A04752g
Drosophila melanogaster (Dme) dme13871 CG5315-PA
(FBgn0038984)
Drosophila melanogaster (Dme) dme13873 CG5315-PB
(FBgn0038984)
Drosophila melanogaster (Dme) dme13872 CG5315-PC
(FBgn0038984)
Danio rerio (Dre) dre18029 ENSDARP00000005569
Danio rerio (Dre) dre12886 ENSDARP00000017631
Danio rerio (Dre) dre18036 ENSDARP00000020891
Danio rerio (Dre) dre18035 ENSDARP00000045955
Takifugu rubripes (Fru) fru16196 SINFRUP00000135111
Takifugu rubripes (Fru) fru13742 SINFRUP00000165160
Gallus gallus (Gga) gga16298 ENSGALP00000000131
(ADIPOR1)		 Q4PKP2
Gallus gallus (Gga) gga1249 ENSGALP00000021199
(ADIPOR2)		 Q4PKP1
Homo sapiens (Hsa) hsa6891 ENSP00000005924
Homo sapiens (Hsa) hsa2874 ENSP00000341785
(ADIPOR1)		 Q96A54
Homo sapiens (Hsa) hsa6890 ENSP00000349616
(ADIPOR2)		 Q86V24
Kluyveromyces lactis (Kla) kla1752 KLLA0C12441g
Kluyveromyces lactis (Kla) kla2127 KLLA0D01331g
Mus musculus (Mmu) mmu1097 ENSMUSP00000027727
(MGI:1919924)		 Q91VH1
Mus musculus (Mmu) mmu22591 ENSMUSP00000032272
(MGI:93830)		 Q8BQS5-1
Neurospora crassa (Ncr) ncr4843 NCU04987.2
Oryza sativa (Osa) osa2378 1909.m00150
Oryza sativa (Osa) osa1441 1925.m00107
Oryza sativa (Osa) osa1477 1926.m00119
Oryza sativa (Osa) osa8350 2543.m00062
Oryza sativa (Osa) osa28017 4222.m00135
Oryza sativa (Osa) osa28184 4226.m00158
Oryza sativa (Osa) osa72406 7221.m00120
Oryza sativa (Osa) osa77836 7476.m00136
Rattus norvegicus (Rno) rno9113 ENSRNOP00000005551
(RGD:1303151)		 Q3YAF8
Rattus norvegicus (Rno) rno22093 ENSRNOP00000010556
(RGD:1307891)		 Q3YAF7
Saccharomyces cerevisiae (Sce) sce1558 YDR492W
(S000002900)
Saccharomyces cerevisiae (Sce) sce5549 YOL002C
(S000005362)
Schizosaccharomyces pombe (Spo) spo4868 SPBC12C2.09c Q09749
Yarrowia lipolytica (Yli) yli4588 YALI0E17677g


GO terms for OrthoMCL results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
IDA
SceS000002900
ISS
SpoSPBC12C2.09c
GO:0005789 endoplasmic reticulum membrane C
IC
SpoSPBC12C2.09c
GO:0005886 plasma membrane C
IDA
SceS000005362
GO:0016020 membrane C
ISS
SceS000005362
S000002900
SpoSPBC12C2.09c
TAS
SceS000002900
GO:0016021 integral to membrane C
ISS
DmeFBgn0038984
SceS000005362
GO:0044459 plasma membrane part C
ISO
MmuMGI:1919924
GO:0004872 receptor activity F
IDA
MmuMGI:93830
MGI:1919924
ISS
AthAt4g37680
At4g38320
At4g30850
At2g24150
At5g20270
GO:0005515 protein binding F
IPI
MmuMGI:93830
MGI:1919924
SceS000005362
GO:0042562 hormone binding F
ISS
DmeFBgn0038984
MmuMGI:93830
GO:0042802 identical protein binding F
IDA
MmuMGI:93830
MGI:1919924
GO:0046872 metal ion binding F
ISS
SceS000002900
S000005362
SpoSPBC12C2.09c
GO:0046982 protein heterodimerization activity F
IPI
MmuMGI:93830
MGI:1919924
GO:0000003 reproduction P
IMP
CelWBGene00021313
GO:0006414 translational elongation P
RCA
SceS000005362
GO:0006629 lipid metabolic process P
ISS
SpoSPBC12C2.09c
GO:0006882 cellular zinc ion homeostasis P
IMP
SceS000002900
S000005362
ISS
SceS000002900
S000005362
SpoSPBC12C2.09c
GO:0006979 response to oxidative stress P
IMP
AthAt2g24150
GO:0007165 signal transduction P
IDA
MmuMGI:93830
MGI:1919924
GO:0009636 response to toxin P
IMP
SceS000005362
GO:0009651 response to salt stress P
IEP
AthAt5g20270
GO:0009725 response to hormone stimulus P
IEP
AthAt5g20270
At2g24150
At4g38320
At4g30850
At4g37680
GO:0009744 response to sucrose stimulus P
IEP
AthAt4g30850
At5g20270
At4g37680
At4g38320
At2g24150
GO:0009755 hormone-mediated signaling pathway P
ISS
DmeFBgn0038984
MmuMGI:93830
GO:0010043 response to zinc ion P
ISS
SceS000002900
S000005362
SpoSPBC12C2.09c
GO:0019395 fatty acid oxidation P
ISS
DmeFBgn0038984
MmuMGI:93830
GO:0030308 negative regulation of cell growth P
ISO
MmuMGI:93830
MGI:1919924
GO:0033210 leptin-mediated signaling pathway P
ISO
MmuMGI:1919924
GO:0033211 adiponectin-mediated signaling
pathway		 P
ISO
MmuMGI:1919924
GO:0044255 cellular lipid metabolic process P
TAS
SceS000002900
S000005362
GO:0046326 positive regulation of glucose
import		 P
ISO
MmuMGI:93830
GO:0046427 positive regulation of JAK-STAT
cascade		 P
ISO
MmuMGI:1919924
GO:0046628 positive regulation of insulin receptor signaling
pathway		 P
ISO
MmuMGI:1919924

Back to the top

Curated yeast ortholog results:

S. pombe
systematic ID		 S. cerevisiae
systematic ID
SPBC12C2.09c
(Q09749)		 YOL002C
(S000005362)


GO terms for curated homolog results:

GO ID GO term GO aspect Evidence codes and associations
GO:0005783 endoplasmic reticulum C
ISS
SpoSPBC12C2.09c
GO:0005789 endoplasmic reticulum membrane C
IC
SpoSPBC12C2.09c
GO:0005886 plasma membrane C
IDA
SceS000005362
GO:0016020 membrane C
ISS
SceS000005362
SpoSPBC12C2.09c
GO:0016021 integral to membrane C
ISS
SceS000005362
GO:0005515 protein binding F
IPI
SceS000005362
GO:0046872 metal ion binding F
ISS
SceS000005362
SpoSPBC12C2.09c
GO:0006414 translational elongation P
RCA
SceS000005362
GO:0006629 lipid metabolic process P
ISS
SpoSPBC12C2.09c
GO:0006882 cellular zinc ion homeostasis P
IMP
SceS000005362
ISS
SceS000005362
SpoSPBC12C2.09c
GO:0009636 response to toxin P
IMP
SceS000005362
GO:0010043 response to zinc ion P
ISS
SceS000005362
SpoSPBC12C2.09c
GO:0044255 cellular lipid metabolic process P
TAS
SceS000005362

Back to the top
YOGY Home YOGY Help

Search for gene by ID or name:

Query species:

Include wild-cards:   

Search for GO info:  

GO info in one table:

s.khadayate@ucl.ac.uk