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Search term: YOL018C


Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name TLG2
SGD link S000005378
Alternative ID YOL018C
Description Syntaxin-like t-SNARE that forms a complex with Tlg1p and Vti1p and mediates fusion of endosome-derived vesicles with the late Golgi; binds Vps45p, which prevents Tlg2p degradation and also facilitates t-SNARE complex formation
Synonyms YOL018C
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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Query species:

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GO info in one table:


KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0809 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING SNARE protein TLG2/Syntaxin 16

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g05710 GI:6714439
Arabidopsis thaliana (Ath) At5g26980 GI:15240425
Caenorhabditis elegans (Cel) CE28155
(WBGene00022534)
GI:17556811 Q9TY08
Drosophila melanogaster (Dme) 7295604
(FBgn0031106)
GI:17647979 Q9VR90
Homo sapiens (Hsa) Hs4507289 GI:4507289
Saccharomyces cerevisiae (Sce) YOL018c
(S000005378)
GI:6324555 Q08144
Schizosaccharomyces pombe (Spo) SPAC823.05c GI:19114744 Q9P6P1
Encephalitozoon cuniculi (Ecu) ECU05g1220 GI:19173662 Q8SVH6
Arabidopsis thaliana (Ath) At3g05710 GI:6714439
Arabidopsis thaliana (Ath) At5g26980 GI:15240425
Caenorhabditis elegans (Cel) CE28155
(WBGene00022534)
GI:17556811 Q9TY08
Drosophila melanogaster (Dme) 7295604
(FBgn0031106)
GI:17647979 Q9VR90
Homo sapiens (Hsa) Hs4507289 GI:4507289
Saccharomyces cerevisiae (Sce) YOL018c
(S000005378)
GI:6324555 Q08144
Schizosaccharomyces pombe (Spo) SPAC823.05c GI:19114744 Q9P6P1
Encephalitozoon cuniculi (Ecu) ECU05g1220 GI:19173662 Q8SVH6


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000138 Golgi trans cisterna C
TAS
SceS000005378
GO:0000139 Golgi membrane C
IC
DmeFBgn0031106
GO:0005764 lysosome C
IDA
DmeFBgn0031106
GO:0005769 early endosome C
TAS
SceS000005378
GO:0005794 Golgi apparatus C
IDA
DmeFBgn0031106
SpoSPAC823.05c
GO:0005802 trans-Golgi network C
IDA
AthAt5g26980
TAS
AthAt5g26980
SceS000005378
GO:0005829 cytosol C
IDA
SpoSPAC823.05c
GO:0005886 plasma membrane C
ISS
DmeFBgn0031106
NAS
DmeFBgn0031106
GO:0016021 integral to membrane C
IDA
DmeFBgn0031106
GO:0030140 trans-Golgi network transport vesicle C
TAS
AthAt5g26980
GO:0031201 SNARE complex C
IPI
SceS000005378
GO:0005484 SNAP receptor activity F
ISS
DmeFBgn0031106
SpoSPAC823.05c
NAS
DmeFBgn0031106
TAS
AthAt5g26980
At3g05710
SceS000005378
GO:0005543 phospholipid binding F
RCA
SceS000005378
GO:0008289 lipid binding F
RCA
SceS000005378
GO:0006605 protein targeting P
RCA
SceS000005378
GO:0006674 inositol phosphorylceramide metabolic
process
P
IGI
SceS000005378
IMP
SceS000005378
GO:0006675 mannosyl-inositol phosphorylceramide metabolic
process
P
IGI
SceS000005378
IMP
SceS000005378
GO:0006886 intracellular protein transport P
NAS
SpoSPAC823.05c
TAS
AthAt3g05710
At5g26980
GO:0006896 Golgi to vacuole transport P
IGI
SceS000005378
GO:0006906 vesicle fusion P
TAS
SceS000005378
GO:0006944 cellular membrane fusion P
TAS
AthAt5g26980
At3g05710
GO:0007269 neurotransmitter secretion P
NAS
DmeFBgn0031106
GO:0010811 positive regulation of cell-substrate
adhesion
P
IMP
SpoSPAC823.05c
GO:0016081 synaptic vesicle docking involved in
exocytosis
P
ISS
DmeFBgn0031106
GO:0016192 vesicle-mediated transport P
IC
SpoSPAC823.05c
NAS
DmeFBgn0031106
GO:0032258 CVT pathway P
IMP
SceS000005378
GO:0032527 protein exit from endoplasmic reticulum P
IGI
SceS000005378
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00022534

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
2791

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) STX16 GI:198041688
Pan troglodytes (Ptr) STX16 GI:114682812
Canis familiaris (Cfa) STX16 GI:73992388
Mus musculus (Mmu) Stx16
(MGI:1923396)
GI:29789393 Q0VGN4
Rattus norvegicus (Rno) Stx16 GI:109469301
Gallus gallus (Gga) STX16 GI:57529381
Drosophila melanogaster (Dme) Syx16
(FBgn0031106)
GI:17647979 Q9VR90
Caenorhabditis elegans (Cel) syn-16
(CE28155;
WBGene00022534)
GI:17556811 Q9TY08
Schizosaccharomyces pombe (Spo) tlg2
(SPAC823.05c)
GI:19114744 Q9P6P1
Saccharomyces cerevisiae (Sce) TLG2
(S000005378)
GI:6324555 Q08144
Kluyveromyces lactis (Kla) KLLA0A10681g GI:50303059
Eremothecium gossypii (Ego) AGOS_AEL026C GI:45190581
Magnaporthe grisea (Mgr) MGG_06883 GI:39977997
Neurospora crassa (Ncr) NCU04119.1 GI:32405692
Arabidopsis thaliana (Ath) SYP42 GI:18411871
Plasmodium falciparum (Pfa) PFL2070w GI:124806741


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000138 Golgi trans cisterna C
TAS
SceS000005378
GO:0000139 Golgi membrane C
IC
DmeFBgn0031106
GO:0005575 cellular_component C
ND
MmuMGI:1923396
GO:0005764 lysosome C
IDA
DmeFBgn0031106
GO:0005769 early endosome C
TAS
SceS000005378
GO:0005792 microsome C
TAS
HsaSTX16
GO:0005794 Golgi apparatus C
IDA
DmeFBgn0031106
SpoSPAC823.05c
GO:0005802 trans-Golgi network C
IDA
AthSYP42
TAS
AthSYP42
SceS000005378
GO:0005829 cytosol C
IDA
SpoSPAC823.05c
GO:0005886 plasma membrane C
ISS
DmeFBgn0031106
NAS
DmeFBgn0031106
GO:0016021 integral to membrane C
IDA
DmeFBgn0031106
GO:0030140 trans-Golgi network transport vesicle C
TAS
AthSYP42
GO:0031201 SNARE complex C
IPI
SceS000005378
TAS
HsaSTX16
GO:0003674 molecular_function F
ND
MmuMGI:1923396
GO:0005484 SNAP receptor activity F
IDA
HsaSTX16
ISS
DmeFBgn0031106
PfaPFL2070w
SpoSPAC823.05c
NAS
DmeFBgn0031106
TAS
AthSYP42
SceS000005378
GO:0005543 phospholipid binding F
RCA
SceS000005378
GO:0008289 lipid binding F
RCA
SceS000005378
GO:0006605 protein targeting P
RCA
SceS000005378
GO:0006674 inositol phosphorylceramide metabolic
process
P
IGI
SceS000005378
IMP
SceS000005378
GO:0006675 mannosyl-inositol phosphorylceramide metabolic
process
P
IGI
SceS000005378
IMP
SceS000005378
GO:0006886 intracellular protein transport P
NAS
SpoSPAC823.05c
TAS
AthSYP42
GO:0006891 intra-Golgi vesicle-mediated transport P
TAS
HsaSTX16
GO:0006896 Golgi to vacuole transport P
IGI
SceS000005378
GO:0006906 vesicle fusion P
TAS
SceS000005378
GO:0006944 cellular membrane fusion P
TAS
AthSYP42
GO:0007269 neurotransmitter secretion P
NAS
DmeFBgn0031106
GO:0008150 biological_process P
ND
MmuMGI:1923396
GO:0010811 positive regulation of cell-substrate
adhesion
P
IMP
SpoSPAC823.05c
GO:0016081 synaptic vesicle docking involved in
exocytosis
P
ISS
DmeFBgn0031106
GO:0016192 vesicle-mediated transport P
IC
SpoSPAC823.05c
NAS
DmeFBgn0031106
GO:0032258 CVT pathway P
IMP
SceS000005378
GO:0032527 protein exit from endoplasmic reticulum P
IGI
SceS000005378
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00022534
GO:0042147 retrograde transport, endosome to
Golgi
P
IDA
HsaSTX16

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1543

Species OrthoMCL
sequence
Model organism
protein page
UniProt link
Anopheles gambiae (Aga) aga15532 ENSANGP00000029690
Ashbya gossypii (Ago) ago2480 AEL026C
Arabidopsis thaliana (Ath) ath12633 At3g05710.1
Arabidopsis thaliana (Ath) ath12634 At3g05710.2
Arabidopsis thaliana (Ath) ath18098 At4g02195.1
Arabidopsis thaliana (Ath) ath24974 At5g26980.1
Caenorhabditis elegans (Cel) cel21172 ZC155.7
(CE28155;
WBGene00022534)
Candida glabrata (Cgl) cgl2012 CAGL0G08932g
Dictyostelium discoideum (Ddi) ddi1670 DDB0167091
Dictyostelium discoideum (Ddi) ddi2453 DDB0217821
Debaryomyces hansenii (Dha) dha6133 DEHA0G09724g
Drosophila melanogaster (Dme) dme18777 CG1467-PA
(FBgn0031106)
Danio rerio (Dre) dre1174 ENSDARP00000012625
Takifugu rubripes (Fru) fru29894 SINFRUP00000144217
Takifugu rubripes (Fru) fru29893 SINFRUP00000144224
Gallus gallus (Gga) gga12186 ENSGALP00000012180
(STX16)
Q5ZK87
Gallus gallus (Gga) gga12187 ENSGALP00000012181
Homo sapiens (Hsa) hsa20509 ENSP00000344234
Homo sapiens (Hsa) hsa20504 ENSP00000348229
(STX16)
O14662-4
Homo sapiens (Hsa) hsa20508 ENSP00000350723
(STX16)
Q6GMS8
Homo sapiens (Hsa) hsa20506 ENSP00000352634
(STX16)
B7ZBM7
Homo sapiens (Hsa) hsa20507 ENSP00000354445
(STX16)
Kluyveromyces lactis (Kla) kla464 KLLA0A10681g
Mus musculus (Mmu) mmu16135 ENSMUSP00000039543
(MGI:1923396)
B7ZCB8
Neurospora crassa (Ncr) ncr3995 NCU04119.2
Oryza sativa (Osa) osa67930 6897.m00140
Plasmodium falciparum (Pfa) pfa5195 PFL2070w
Rattus norvegicus (Rno) rno20390 ENSRNOP00000007054
(RGD:1309423)
Saccharomyces cerevisiae (Sce) sce5567 YOL018C
(S000005378)
Schizosaccharomyces pombe (Spo) spo3250 SPAC823.05c Q9P6P1
Yarrowia lipolytica (Yli) yli5243 YALI0E33165g