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Search term: YOL038W

Gene summary:

Species Saccharomyces cerevisiae (Sce)
Primary name PRE6
SGD link S000005398
Alternative ID YOL038W
Description Alpha 4 subunit of the 20S proteasome; may replace alpha 3 subunit (Pre9p) under stress conditions to create a more active proteasomal isoform; GFP-fusion protein relocates from cytosol to the mitochondrial surface upon oxidative stress
Synonyms YOL038W
Datasets
KOGs
Inparanoid
HomoloGene
OrthoMCL
Curated

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GO info in one table:

KOG results:

KOG name Phylogenetic pattern
(and link to KOGs with this pattern)
KOG0183 ACDHYPE

KOGs classification KOGs description
CELLULAR PROCESSES AND SIGNALING 20S proteasome, regulatory subunit alpha type PSMA7/PRE6

Species KOG link NCBI link UniProt link
Arabidopsis thaliana (Ath) At3g51260 GI:15230435
Arabidopsis thaliana (Ath) At5g66140 GI:15239271
Caenorhabditis elegans (Cel) CE05371
(WBGene00003925)		 GI:17508491 Q95005
Drosophila melanogaster (Dme) 7291795 GI:19922898
Drosophila melanogaster (Dme) 7293190
(FBgn0004066)		 GI:17933602
Drosophila melanogaster (Dme) 7300653 GI:12643241
Homo sapiens (Hsa) Hs18573596 GI:18573596
Homo sapiens (Hsa) Hs21389549 GI:19263962
Homo sapiens (Hsa) Hs4506189
(PSMA7)		 GI:4506189 O14818
Saccharomyces cerevisiae (Sce) YOL038w
(S000005398)		 GI:6324535 P40303
Schizosaccharomyces pombe (Spo) SPBC106.16 GI:19111957 Q10329
Encephalitozoon cuniculi (Ecu) ECU07g1040 GI:19074527 Q8SRJ0
Arabidopsis thaliana (Ath) At3g51260 GI:15230435
Arabidopsis thaliana (Ath) At5g66140 GI:15239271
Caenorhabditis elegans (Cel) CE05371
(WBGene00003925)		 GI:17508491 Q95005
Drosophila melanogaster (Dme) 7291795 GI:19922898
Drosophila melanogaster (Dme) 7293190
(FBgn0004066)		 GI:17933602
Drosophila melanogaster (Dme) 7300653 GI:12643241
Homo sapiens (Hsa) Hs18573596 GI:18573596
Homo sapiens (Hsa) Hs21389549 GI:19263962
Homo sapiens (Hsa) Hs4506189
(PSMA7)		 GI:4506189 O14818
Saccharomyces cerevisiae (Sce) YOL038w
(S000005398)		 GI:6324535 P40303
Schizosaccharomyces pombe (Spo) SPBC106.16 GI:19111957 Q10329
Encephalitozoon cuniculi (Ecu) ECU07g1040 GI:19074527 Q8SRJ0
Arabidopsis thaliana (Ath) At3g51260 GI:15230435
Arabidopsis thaliana (Ath) At5g66140 GI:15239271
Caenorhabditis elegans (Cel) CE05371
(WBGene00003925)		 GI:17508491 Q95005
Drosophila melanogaster (Dme) 7291795 GI:19922898
Drosophila melanogaster (Dme) 7293190
(FBgn0004066)		 GI:17933602
Drosophila melanogaster (Dme) 7300653 GI:12643241
Homo sapiens (Hsa) Hs18573596 GI:18573596
Homo sapiens (Hsa) Hs21389549 GI:19263962
Homo sapiens (Hsa) Hs4506189
(PSMA7)		 GI:4506189 O14818
Saccharomyces cerevisiae (Sce) YOL038w
(S000005398)		 GI:6324535 P40303
Schizosaccharomyces pombe (Spo) SPBC106.16 GI:19111957 Q10329
Encephalitozoon cuniculi (Ecu) ECU07g1040 GI:19074527 Q8SRJ0


GO terms for KOG results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000502 proteasome complex C
NAS
DmeFBgn0004066
TAS
HsaPSMA7
GO:0005634 nucleus C
IDA
AthAt3g51260
SceS000005398
SpoSPBC106.16
TAS
SpoSPBC106.16
GO:0005739 mitochondrion C
IDA
SceS000005398
GO:0005773 vacuole C
IDA
AthAt5g66140
At3g51260
GO:0005819 spindle C
IDA
AthAt3g51260
GO:0005829 cytosol C
IDA
SpoSPBC106.16
GO:0005839 proteasome core complex C
ISS
DmeFBgn0004066
TAS
AthAt5g66140
At3g51260
GO:0005875 microtubule associated complex C
IDA
DmeFBgn0004066
GO:0005886 plasma membrane C
IDA
AthAt3g51260
GO:0009507 chloroplast C
IDA
AthAt5g66140
At3g51260
GO:0009524 phragmoplast C
IDA
AthAt3g51260
GO:0019773 proteasome core complex, alpha-subunit
complex		 C
IDA
SceS000005398
SpoSPBC106.16
ISS
AthAt5g66140
NAS
AthAt3g51260
GO:0022626 cytosolic ribosome C
IDA
AthAt3g51260
GO:0034515 proteasome storage granule C
IDA
SceS000005398
GO:0042175 nuclear membrane-endoplasmic reticulum
network		 C
IDA
SceS000005398
GO:0003674 molecular_function F
ND
SceS000005398
GO:0004175 endopeptidase activity F
ISS
DmeFBgn0004066
SpoSPBC106.16
NAS
DmeFBgn0004066
GO:0005515 protein binding F
IPI
HsaPSMA7
GO:0008233 peptidase activity F
ISS
AthAt5g66140
At3g51260
GO:0042802 identical protein binding F
IPI
HsaPSMA7
GO:0000003 reproduction P
IMP
CelWBGene00003925
GO:0000278 mitotic cell cycle P
IC
SpoSPBC106.16
GO:0002119 nematode larval development P
IMP
CelWBGene00003925
GO:0006508 proteolysis P
RCA
SceS000005398
GO:0006511 ubiquitin-dependent protein catabolic
process		 P
NAS
DmeFBgn0004066
TAS
AthAt5g66140
At3g51260
GO:0006974 response to DNA damage stimulus P
IMP
DmeFBgn0004066
GO:0007346 regulation of mitotic cell cycle P
NAS
SpoSPBC106.16
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00003925
GO:0010499 proteasomal ubiquitin-independent protein
catabolic process		 P
IDA
SceS000005398
GO:0031145 anaphase-promoting complex-dependent proteasomal
ubiquitin-dependent protein catabolic
process		 P
EXP
HsaPSMA7
GO:0040007 growth P
IMP
CelWBGene00003925
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00003925
GO:0040011 locomotion P
IMP
CelWBGene00003925
GO:0043161 proteasomal ubiquitin-dependent protein catabolic
process		 P
IDA
SceS000005398
ISS
SpoSPBC106.16
GO:0051436 negative regulation of ubiquitin-protein ligase
activity involved in mitotic cell
cycle		 P
EXP
HsaPSMA7
GO:0051437 positive regulation of ubiquitin-protein ligase
activity involved in mitotic cell
cycle		 P
EXP
HsaPSMA7

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HomoloGene results:

HomoloGene cluster Phylogenetic pattern
2086

Species Gene ID NCBI link UniProt link
Homo sapiens (Hsa) PSMA8 GI:68303561
Pan troglodytes (Ptr) PSMA8 GI:114672629
Canis familiaris (Cfa) PSMA8 GI:73961787
Drosophila melanogaster (Dme) Pros28.1
(FBgn0004066)		 GI:17933602
Anopheles gambiae (Aga) AgaP_AGAP005423 GI:118786445
Caenorhabditis elegans (Cel) pas-4
(CE05371;
WBGene00003925)		 GI:17508491 Q95005
Schizosaccharomyces pombe (Spo) SPBC106.16 GI:19111957 Q10329
Saccharomyces cerevisiae (Sce) PRE6
(S000005398)		 GI:6324535 P40303
Kluyveromyces lactis (Kla) KLLA0B11836g GI:50304213
Eremothecium gossypii (Ego) AGOS_AAR012C GI:45184835
Magnaporthe grisea (Mgr) MGG_06472 GI:39977139
Neurospora crassa (Ncr) NCU06440.1 GI:32411629
Arabidopsis thaliana (Ath) PAD1 GI:15230435
Arabidopsis thaliana (Ath) PAD2 GI:15239271
Oryza sativa (Osa) Os08g0548900 GI:115477683
Oryza sativa (Osa) Os09g0538200 GI:115480403
Plasmodium falciparum (Pfa) MAL13P1.270 GI:124513790


GO terms for Homologene results:

GO ID GO term GO aspect Evidence codes and associations
GO:0000502 proteasome complex C
NAS
DmeFBgn0004066
GO:0005575 cellular_component C
ND
AthPAD1
GO:0005634 nucleus C
IDA
AthPAD1
SceS000005398
SpoSPBC106.16
TAS
SpoSPBC106.16
GO:0005739 mitochondrion C
IDA
SceS000005398
GO:0005773 vacuole C
IDA
AthPAD2
PAD1
GO:0005819 spindle C
IDA
AthPAD1
GO:0005829 cytosol C
IDA
SpoSPBC106.16
GO:0005839 proteasome core complex C
ISS
DmeFBgn0004066
TAS
AthPAD2
PAD1
GO:0005875 microtubule associated complex C
IDA
DmeFBgn0004066
GO:0005886 plasma membrane C
IDA
AthPAD1
GO:0009507 chloroplast C
IDA
AthPAD2
PAD1
GO:0009524 phragmoplast C
IDA
AthPAD1
GO:0019773 proteasome core complex, alpha-subunit
complex		 C
IDA
SceS000005398
SpoSPBC106.16
ISS
AthPAD2
NAS
AthPAD1
GO:0022626 cytosolic ribosome C
IDA
AthPAD1
GO:0034515 proteasome storage granule C
IDA
SceS000005398
GO:0042175 nuclear membrane-endoplasmic reticulum
network		 C
IDA
SceS000005398
GO:0003674 molecular_function F
ND
AthPAD1
SceS000005398
GO:0004175 endopeptidase activity F
ISS
DmeFBgn0004066
SpoSPBC106.16
NAS
DmeFBgn0004066
GO:0008233 peptidase activity F
ISS
AthPAD1
PAD2
GO:0000003 reproduction P
IMP
CelWBGene00003925
GO:0000278 mitotic cell cycle P
IC
SpoSPBC106.16
GO:0002119 nematode larval development P
IMP
CelWBGene00003925
GO:0006508 proteolysis P
RCA
SceS000005398
GO:0006511 ubiquitin-dependent protein catabolic
process		 P
NAS
DmeFBgn0004066
TAS
AthPAD1
PAD2
GO:0006974 response to DNA damage stimulus P
IMP
DmeFBgn0004066
GO:0007346 regulation of mitotic cell cycle P
NAS
SpoSPBC106.16
GO:0009700 indole phytoalexin biosynthetic
process		 P
IMP
AthPAD1
GO:0009792 embryo development ending in birth or egg
hatching		 P
IMP
CelWBGene00003925
GO:0009816 defense response to bacterium, incompatible
interaction		 P
IMP
AthPAD1
GO:0010499 proteasomal ubiquitin-independent protein
catabolic process		 P
IDA
SceS000005398
GO:0040007 growth P
IMP
CelWBGene00003925
GO:0040010 positive regulation of growth rate P
IMP
CelWBGene00003925
GO:0040011 locomotion P
IMP
CelWBGene00003925
GO:0043161 proteasomal ubiquitin-dependent protein catabolic
process		 P
IDA
SceS000005398
ISS
SpoSPBC106.16

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OrthoMCL results:

Selected databases only

OrthoMCL cluster Phylogenetic pattern
OG1_1693

Species OrthoMCL
sequence		 Model organism
protein page		 UniProt link
Anopheles gambiae (Aga) aga836 ENSANGP00000007022
Ashbya gossypii (Ago) ago198 AAR012C
Arabidopsis thaliana (Ath) ath16443 At3g51260.1
Arabidopsis thaliana (Ath) ath28783 At5g66140.1
Caenorhabditis elegans (Cel) cel3564 C36B1.4
(CE05371;
WBGene00003925)
Candida glabrata (Cgl) cgl1284 CAGL0F01199g
Cryptococcus neoformans (Cne) cne668 163.m03869
Dictyostelium discoideum (Ddi) ddi11808 DDB0185059
Debaryomyces hansenii (Dha) dha5055 DEHA0F15081g
Drosophila melanogaster (Dme) dme13560 CG17268-PA
(FBgn0017557)
Drosophila melanogaster (Dme) dme18125 CG3422-PA
(FBgn0004066)
Danio rerio (Dre) dre24865 ENSDARP00000006445
(zgc:77139)		 Q6P0I2
Takifugu rubripes (Fru) fru16950 SINFRUP00000130771
Gallus gallus (Gga) gga11950 ENSGALP00000008224
(PSMA7)		 O13268
Homo sapiens (Hsa) hsa20562 ENSP00000217153
Homo sapiens (Hsa) hsa14836 ENSP00000311121
(PSMA8)		 Q8TAA3-1
Kluyveromyces lactis (Kla) kla1054 KLLA0B11836g
Mus musculus (Mmu) mmu16236 ENSMUSP00000029082
(MGI:1347070)		 Q9Z2U0
Mus musculus (Mmu) mmu12343 ENSMUSP00000042590
(MGI:1920927)		 Q9CWH6
Neurospora crassa (Ncr) ncr6259 NCU06440.2
Oryza sativa (Osa) osa60426 6568.m00179
Oryza sativa (Osa) osa66066 6776.m00148
Oryza sativa (Osa) osa64105 6792.m00075
Plasmodium falciparum (Pfa) pfa4016 MAL13P1.270
Rattus norvegicus (Rno) rno20461 ENSRNOP00000011724
(RGD:61851)		 P48004-1
Saccharomyces cerevisiae (Sce) sce5589 YOL038W
(S000005398)
Schizosaccharomyces pombe (Spo) spo3546 SPBC106.16 Q10329
Yarrowia lipolytica (Yli) yli1329 YALI0B14267g